(6 nodes) Myogenic factor, and beta-catenin-TCF7L2 complex network (Cercocebus atys)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MYOG	Myogenin. (249 aa)
	LOC105578089	BHLH domain-containing protein. (589 aa)
	TCF12	Transcription factor 12. (706 aa)
	MYOD1	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (319 aa)
	MYF5	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
	TCF4	Transcription factor 4. (773 aa)

Your Current Organism:

Cercocebus atys

NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC105578089	MYF5	ENSCATP00000003982	ENSCATP00000039009	BHLH domain-containing protein.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.811
LOC105578089	MYOD1	ENSCATP00000003982	ENSCATP00000015302	BHLH domain-containing protein.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.866
LOC105578089	MYOG	ENSCATP00000003982	ENSCATP00000000493	BHLH domain-containing protein.	Myogenin.	0.817
LOC105578089	TCF12	ENSCATP00000003982	ENSCATP00000004629	BHLH domain-containing protein.	Transcription factor 12.	0.402
LOC105578089	TCF4	ENSCATP00000003982	ENSCATP00000039804	BHLH domain-containing protein.	Transcription factor 4.	0.402
MYF5	LOC105578089	ENSCATP00000039009	ENSCATP00000003982	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	BHLH domain-containing protein.	0.811
MYF5	MYOG	ENSCATP00000039009	ENSCATP00000000493	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	Myogenin.	0.628
MYF5	TCF12	ENSCATP00000039009	ENSCATP00000004629	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	Transcription factor 12.	0.795
MYF5	TCF4	ENSCATP00000039009	ENSCATP00000039804	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	Transcription factor 4.	0.780
MYOD1	LOC105578089	ENSCATP00000015302	ENSCATP00000003982	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	BHLH domain-containing protein.	0.866
MYOD1	MYOG	ENSCATP00000015302	ENSCATP00000000493	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	Myogenin.	0.818
MYOD1	TCF12	ENSCATP00000015302	ENSCATP00000004629	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	Transcription factor 12.	0.926
MYOD1	TCF4	ENSCATP00000015302	ENSCATP00000039804	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	Transcription factor 4.	0.896
MYOG	LOC105578089	ENSCATP00000000493	ENSCATP00000003982	Myogenin.	BHLH domain-containing protein.	0.817
MYOG	MYF5	ENSCATP00000000493	ENSCATP00000039009	Myogenin.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.628
MYOG	MYOD1	ENSCATP00000000493	ENSCATP00000015302	Myogenin.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.818
MYOG	TCF12	ENSCATP00000000493	ENSCATP00000004629	Myogenin.	Transcription factor 12.	0.845
MYOG	TCF4	ENSCATP00000000493	ENSCATP00000039804	Myogenin.	Transcription factor 4.	0.850
TCF12	LOC105578089	ENSCATP00000004629	ENSCATP00000003982	Transcription factor 12.	BHLH domain-containing protein.	0.402
TCF12	MYF5	ENSCATP00000004629	ENSCATP00000039009	Transcription factor 12.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.795