11 items (Cercocebus atys) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PAX5	Paired box 5. (313 aa)
	TBX21	T-box transcription factor 21. (535 aa)
	IRF4	Interferon regulatory factor 4. (451 aa)
	RUNX3	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (428 aa)
	ZFHX3	Zinc finger homeobox 3. (3693 aa)
	ETS1	ETS proto-oncogene 1, transcription factor. (548 aa)
	RUNX2	RUNX family transcription factor 2. (635 aa)
	RUNX1	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa)
	PPM1D	Protein phosphatase, Mg2+/Mn2+ dependent 1D. (605 aa)
	CBFB	Core-binding factor subunit beta. (182 aa)
	ERG	ETS transcription factor ERG. (486 aa)

Your Current Organism:

Cercocebus atys

NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBFB	ERG	ENSCATP00000040224	ENSCATP00000045619	Core-binding factor subunit beta.	ETS transcription factor ERG.	0.692
CBFB	ETS1	ENSCATP00000040224	ENSCATP00000024082	Core-binding factor subunit beta.	ETS proto-oncogene 1, transcription factor.	0.756
CBFB	PAX5	ENSCATP00000040224	ENSCATP00000000778	Core-binding factor subunit beta.	Paired box 5.	0.545
CBFB	PPM1D	ENSCATP00000040224	ENSCATP00000036256	Core-binding factor subunit beta.	Protein phosphatase, Mg2+/Mn2+ dependent 1D.	0.867
CBFB	RUNX1	ENSCATP00000040224	ENSCATP00000035566	Core-binding factor subunit beta.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.979
CBFB	RUNX2	ENSCATP00000040224	ENSCATP00000027316	Core-binding factor subunit beta.	RUNX family transcription factor 2.	0.973
CBFB	RUNX3	ENSCATP00000040224	ENSCATP00000005015	Core-binding factor subunit beta.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.958
ERG	CBFB	ENSCATP00000045619	ENSCATP00000040224	ETS transcription factor ERG.	Core-binding factor subunit beta.	0.692
ERG	RUNX1	ENSCATP00000045619	ENSCATP00000035566	ETS transcription factor ERG.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.600
ERG	RUNX2	ENSCATP00000045619	ENSCATP00000027316	ETS transcription factor ERG.	RUNX family transcription factor 2.	0.778
ERG	RUNX3	ENSCATP00000045619	ENSCATP00000005015	ETS transcription factor ERG.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.506
ETS1	CBFB	ENSCATP00000024082	ENSCATP00000040224	ETS proto-oncogene 1, transcription factor.	Core-binding factor subunit beta.	0.756
ETS1	PAX5	ENSCATP00000024082	ENSCATP00000000778	ETS proto-oncogene 1, transcription factor.	Paired box 5.	0.918
ETS1	RUNX1	ENSCATP00000024082	ENSCATP00000035566	ETS proto-oncogene 1, transcription factor.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.925
ETS1	RUNX2	ENSCATP00000024082	ENSCATP00000027316	ETS proto-oncogene 1, transcription factor.	RUNX family transcription factor 2.	0.858
ETS1	RUNX3	ENSCATP00000024082	ENSCATP00000005015	ETS proto-oncogene 1, transcription factor.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.838
ETS1	TBX21	ENSCATP00000024082	ENSCATP00000002426	ETS proto-oncogene 1, transcription factor.	T-box transcription factor 21.	0.515
IRF4	PAX5	ENSCATP00000004452	ENSCATP00000000778	Interferon regulatory factor 4.	Paired box 5.	0.761
IRF4	RUNX1	ENSCATP00000004452	ENSCATP00000035566	Interferon regulatory factor 4.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.487
PAX5	CBFB	ENSCATP00000000778	ENSCATP00000040224	Paired box 5.	Core-binding factor subunit beta.	0.545