STRINGSTRING
EME1 EME1 ENSCATP00000000544 ENSCATP00000000544 FAAP100 FAAP100 FANCA FANCA FANCG FANCG FANCC FANCC ENSCATP00000014233 ENSCATP00000014233 FANCM FANCM FAN1 FAN1 FANCE FANCE EME2 EME2 FANCB FANCB CENPS-CORT CENPS-CORT CENPX CENPX FAAP24 FAAP24 FANCI FANCI ENSCATP00000029234 ENSCATP00000029234 MUS81 MUS81 FANCD2 FANCD2 UBE2T UBE2T FANCL FANCL FAAP20 FAAP20 SLX1A SLX1A ENSCATP00000041476 ENSCATP00000041476 SLX4 SLX4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EME1Essential meiotic structure-specific endonuclease 1. (584 aa)
ENSCATP00000000544NTF2 domain-containing protein. (120 aa)
FAAP100FA core complex associated protein 100. (881 aa)
FANCAFA complementation group A. (1430 aa)
FANCGFA complementation group G. (622 aa)
FANCCFanconi anemia group C protein homolog; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1. (558 aa)
ENSCATP00000014233Uncharacterized protein. (276 aa)
FANCMFA complementation group M. (2050 aa)
FAN1Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (1016 aa)
FANCEFA complementation group E. (536 aa)
EME2Essential meiotic structure-specific endonuclease subunit 2. (379 aa)
FANCBFA complementation group B. (858 aa)
CENPS-CORTCENPS-CORT readthrough. (143 aa)
CENPXCentromere protein X. (133 aa)
FAAP24FA core complex associated protein 24. (215 aa)
FANCIFA complementation group I. (1328 aa)
ENSCATP00000029234NTF2 domain-containing protein. (113 aa)
MUS81MUS81 structure-specific endonuclease subunit. (559 aa)
FANCD2Uncharacterized protein. (1382 aa)
UBE2TUbiquitin conjugating enzyme E2 T; Belongs to the ubiquitin-conjugating enzyme family. (197 aa)
FANCLFA complementation group L. (380 aa)
FAAP20Uncharacterized protein. (184 aa)
SLX1AStructure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products. (304 aa)
ENSCATP00000041476NTF2 domain-containing protein. (119 aa)
SLX4SLX4 structure-specific endonuclease subunit. (1813 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.