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| | RUVBL1 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa) |
| | TRIM24 | Tripartite motif containing 24. (1050 aa) |
| | PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) |
| | HDAC8 | Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (415 aa) |
| | PHF12 | PHD finger protein 12. (1004 aa) |
| | LRWD1 | Leucine rich repeats and WD repeat domain containing 1. (647 aa) |
| | ACTR8 | Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. (624 aa) |
| | MCM4 | DNA helicase; Belongs to the MCM family. (863 aa) |
| | CCDC155 | Coiled-coil domain containing 155. (562 aa) |
| | INO80E | INO80 complex subunit E. (244 aa) |
| | MCM3 | DNA helicase; Belongs to the MCM family. (853 aa) |
| | BRCA2 | BRCA2 DNA repair associated. (3419 aa) |
| | NOL6 | Nucleolar protein 6. (1157 aa) |
| | SMC2 | Structural maintenance of chromosomes protein. (1197 aa) |
| | SMARCE1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1. (411 aa) |
| | ENSCATP00000009181 | HMG box domain-containing protein. (177 aa) |
| | BRD8 | Bromodomain containing 8. (1243 aa) |
| | PBRM1 | Polybromo 1. (1725 aa) |
| | SMC4 | Structural maintenance of chromosomes protein. (1287 aa) |
| | SYN1 | Synapsin I. (705 aa) |
| | CHEK1 | Checkpoint kinase 1. (493 aa) |
| | RAD9A | Cell cycle checkpoint control protein; Belongs to the rad9 family. (390 aa) |
| | ENSCATP00000005896 | TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (292 aa) |
| | MACROH2A2 | Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa) |
| | P3H4 | Prolyl 3-hydroxylase family member 4 (non-enzymatic). (437 aa) |
| | ORC5 | Origin recognition complex subunit 5. (435 aa) |
| | CHD1 | Chromodomain helicase DNA binding protein 1. (1712 aa) |
| | BIRC5 | Uncharacterized protein. (147 aa) |
| | ACTR5 | Uncharacterized protein; Belongs to the actin family. (403 aa) |
| | TRRAP | Transformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. (3895 aa) |
| | CDC45 | Cell division cycle 45. (598 aa) |
| | ZNHIT1 | Zinc finger HIT-type containing 1. (154 aa) |
| | NCAPG | Non-SMC condensin I complex subunit G. (1044 aa) |
| | MCM10 | Minichromosome maintenance 10 replication initiation factor. (877 aa) |
| | INO80C | YL1_C domain-containing protein. (228 aa) |
| | INO80B | PAPA-1 domain-containing protein. (373 aa) |
| | ANP32E | Uncharacterized protein. (226 aa) |
| | POLE2 | DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa) |
| | BRMS1 | BRMS1 transcriptional repressor and anoikis regulator. (246 aa) |
| | SAP130 | Sin3A associated protein 130. (1089 aa) |
| | LRIF1 | Ligand dependent nuclear receptor interacting factor 1. (760 aa) |
| | ORC2 | Origin recognition complex subunit 2. (577 aa) |
| | ACTL6A | Actin like 6A; Belongs to the actin family. (429 aa) |
| | POLA2 | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (598 aa) |
| | FAM9A | Family with sequence similarity 9 member A. (286 aa) |
| | ENSCATP00000005102 | annotation not available (136 aa) |
| | RRS1 | Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (365 aa) |
| | LOC105593169 | Histone H3.1. (136 aa) |
| | ENSCATP00000004608 | annotation not available (136 aa) |
| | ENSCATP00000004425 | annotation not available (136 aa) |
| | NIFK | Nucleolar protein interacting with the FHA domain of MKI67. (293 aa) |
| | CFDP1 | Craniofacial development protein 1; May play a role during embryogenesis. (299 aa) |
| | SPIDR | Scaffold protein involved in DNA repair. (924 aa) |
| | SYCP2L | Synaptonemal complex protein 2 like. (787 aa) |
| | LRPPRC | PPR_long domain-containing protein. (1461 aa) |
| | LOC105572650 | Histone H3.1. (136 aa) |
| | SHOC1 | Shortage in chiasmata 1. (1444 aa) |
| | ENSCATP00000002663 | annotation not available (136 aa) |
| | HORMAD2 | HORMA domain containing 2. (307 aa) |
| | POLE | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2286 aa) |
| | BAZ1A | Bromodomain adjacent to zinc finger domain 1A. (1556 aa) |
| | H3C6 | Histone H3.1. (136 aa) |
| | NEK2 | NIMA related kinase 2. (445 aa) |
| | HUS1B | Checkpoint protein; Belongs to the HUS1 family. (277 aa) |
| | CDX2 | Caudal type homeobox 2. (264 aa) |
| | SYCP2 | Synaptonemal complex protein 2. (1530 aa) |
| | BRD4 | Bromodomain containing 4. (1217 aa) |
| | NUFIP1 | Nuclear FMR1 interacting protein 1. (496 aa) |
| | ENSCATP00000000344 | Histone H3; Belongs to the histone H3 family. (136 aa) |
| | WAPL | WAPL cohesin release factor. (1189 aa) |
| | RPA3 | Replication protein A3. (121 aa) |
| | DHX9 | DExH-box helicase 9. (1275 aa) |
| | STAG2 | Stromal antigen 2. (1268 aa) |
| | MCM6 | DNA helicase; Belongs to the MCM family. (821 aa) |
| | ENSCATP00000010534 | Sld5 domain-containing protein. (165 aa) |
| | SMARCB1 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (385 aa) |
| | MCM2 | DNA helicase; Belongs to the MCM family. (904 aa) |
| | AGO3 | Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (860 aa) |
| | POLD1 | DNA polymerase. (1107 aa) |
| | CCDC36 | Coiled-coil domain containing 36. (599 aa) |
| | TOPBP1 | DNA topoisomerase II binding protein 1. (1527 aa) |
| | ORC4 | Origin recognition complex subunit 4. (339 aa) |
| | ADD3 | Adducin 3. (706 aa) |
| | RNF212 | Uncharacterized protein. (273 aa) |
| | MEI4 | Meiotic double-stranded break formation protein 4. (384 aa) |
| | INO80D | INO80 complex subunit D. (1027 aa) |
| | ING1 | Inhibitor of growth protein. (397 aa) |
| | RPA2 | Replication protein A2. (270 aa) |
| | BRCA1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1871 aa) |
| | SLX4 | SLX4 structure-specific endonuclease subunit. (1813 aa) |
| | SINHCAF | SIN3-HDAC complex associated factor. (221 aa) |
| | EXOSC9 | Exosome component 9. (456 aa) |
| | PSMC3IP | PSMC3 interacting protein. (217 aa) |
| | HDAC1 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa) |
| | SMC3 | Structural maintenance of chromosomes 3. (1007 aa) |
| | MCM5 | DNA helicase; Belongs to the MCM family. (734 aa) |
| | SIN3B | SIN3 transcription regulator family member B. (1159 aa) |
| | GINS2 | DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (185 aa) |
| | PINX1 | PIN2 (TERF1) interacting telomerase inhibitor 1. (322 aa) |
| | OGT | O-linked N-acetylglucosamine (GlcNAc) transferase. (1046 aa) |
| | POLE3 | DNA polymerase epsilon 3, accessory subunit. (147 aa) |
| | POLD3 | Uncharacterized protein. (466 aa) |
| | ORC3 | Origin recognition complex subunit 3. (716 aa) |
| | CCNB1IP1 | Cyclin B1 interacting protein 1. (277 aa) |
| | SETX | Senataxin. (2653 aa) |
| | PLK1 | Serine/threonine-protein kinase PLK. (603 aa) |
| | EP400 | E1A binding protein p400. (3065 aa) |
| | RAD9B | Cell cycle checkpoint control protein; Belongs to the rad9 family. (417 aa) |
| | FAM9C | Family with sequence similarity 9 member C. (166 aa) |
| | ORC1 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (858 aa) |
| | HDAC2 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa) |
| | GINS4 | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (223 aa) |
| | ENSCATP00000039473 | EP400_N domain-containing protein. (420 aa) |
| | TTN | Titin. (32000 aa) |
| | NFRKB | Nuclear factor related to kappaB binding protein. (1287 aa) |
| | ORC6 | Origin recognition complex subunit 6. (229 aa) |
| | ARID4B | AT-rich interaction domain 4B. (1314 aa) |
| | ENSCATP00000039008 | Uncharacterized protein. (112 aa) |
| | ENSCATP00000038940 | Uncharacterized protein. (566 aa) |
| | SMCHD1 | Structural maintenance of chromosomes flexible hinge domain containing 1. (2005 aa) |
| | ZRANB3 | Zinc finger RANBP2-type containing 3. (1049 aa) |
| | SIRT7 | Sirtuin 7. (400 aa) |
| | SPO11 | SPO11 initiator of meiotic double stranded breaks. (396 aa) |
| | SUN2 | Sad1 and UNC84 domain containing 2. (728 aa) |
| | C17orf64 | Chromosome 17 open reading frame 64. (236 aa) |
| | C14orf39 | Chromosome 14 open reading frame 39. (588 aa) |
| | SYCE2 | Synaptonemal complex central element protein 2. (218 aa) |
| | TEX11 | Testis expressed 11. (925 aa) |
| | NCAPH | Condensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. (740 aa) |
| | RAD21L1 | RAD21 cohesin complex component like 1. (556 aa) |
| | GINS3 | GINS complex subunit 3. (255 aa) |
| | TEX12 | Testis expressed 12. (123 aa) |
| | SYCP3 | Cor1 domain-containing protein. (236 aa) |
| | KIFAP3 | Kinesin associated protein 3. (734 aa) |
| | ENSCATP00000036401 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (262 aa) |
| | MMS22L | MMS22 like, DNA repair protein. (1243 aa) |
| | MLH1 | MutL homolog 1. (756 aa) |
| | SLX1A | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products. (304 aa) |
| | SMC1B | Structural maintenance of chromosomes protein. (1235 aa) |
| | SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (944 aa) |
| | INO80 | INO80 complex ATPase subunit. (1556 aa) |
| | POLD2 | DNA polymerase delta 2, accessory subunit. (504 aa) |
| | BLM | BLM RecQ like helicase. (1416 aa) |
| | SYCE1L | Synaptonemal complex central element protein 1 like. (242 aa) |
| | BRMS1L | BRMS1 like transcriptional repressor. (323 aa) |
| | TIPIN | TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (307 aa) |
| | SPEGNB | SPEG neighbor. (238 aa) |
| | HORMAD1 | HORMA domain containing 1. (394 aa) |
| | FKBP6 | Peptidylprolyl isomerase. (327 aa) |
| | RNF212B | Ring finger protein 212B. (300 aa) |
| | POLA1 | DNA polymerase. (1469 aa) |
| | E2F1 | E2F transcription factor 1. (437 aa) |
| | DMAP1 | DNA methyltransferase 1 associated protein 1. (467 aa) |
| | CPSF6 | Cleavage and polyadenylation specific factor 6. (588 aa) |
| | SYCP1 | Synaptonemal complex protein 1. (976 aa) |
| | MCRS1 | Microspherule protein 1. (505 aa) |
| | SETD5 | SET domain containing 5. (1461 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa) |
| | ING2 | Inhibitor of growth protein. (280 aa) |
| | SMC1A | Structural maintenance of chromosomes protein. (1233 aa) |
| | KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (537 aa) |
| | SRCAP | Uncharacterized protein. (3229 aa) |
| | MUS81 | MUS81 structure-specific endonuclease subunit. (559 aa) |
| | SYCE3 | Synaptonemal complex central element protein 3. (88 aa) |
| | REC8 | REC8 meiotic recombination protein. (549 aa) |
| | HMGA2 | High mobility group AT-hook 2. (147 aa) |
| | UBE2I | Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family. (237 aa) |
| | RSPH1 | Radial spoke head component 1. (292 aa) |
| | ING3 | Inhibitor of growth protein. (418 aa) |
| | MLH3 | MutL homolog 3. (1436 aa) |
| | HSPA2 | Heat shock protein family A (Hsp70) member 2; Belongs to the heat shock protein 70 family. (602 aa) |
| | ENSCATP00000028490 | Uncharacterized protein. (166 aa) |
| | SWI5 | SWI5 homologous recombination repair protein. (205 aa) |
| | RUVBL2 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (465 aa) |
| | FAM9B | Family with sequence similarity 9 member B. (226 aa) |
| | ENSCATP00000027507 | Uncharacterized protein. (128 aa) |
| | INCENP | Inner centromere protein. (768 aa) |
| | SAP30L | SAP30 like. (191 aa) |
| | DMC1 | Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily. (319 aa) |
| | MACROH2A1 | Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (371 aa) |
| | ENSCATP00000026110 | Uncharacterized protein. (222 aa) |
| | ZMIZ2 | Zinc finger MIZ-type containing 2. (920 aa) |
| | TONSL | Tonsoku like, DNA repair protein. (1390 aa) |
| | LOC105575333 | Uncharacterized protein; Belongs to the actin family. (488 aa) |
| | CHRAC1 | Chromatin accessibility complex subunit 1. (131 aa) |
| | ETAA1 | ETAA1 activator of ATR kinase. (898 aa) |
| | TIMELESS | Timeless circadian regulator. (1208 aa) |
| | STAG3 | Stromal antigen 3. (1268 aa) |
| | TET1 | Tet methylcytosine dioxygenase 1. (2132 aa) |
| | MSH4 | MutS homolog 4. (935 aa) |
| | SMARCAD1 | Uncharacterized protein. (1026 aa) |
| | GINS1 | GINS complex subunit 1. (196 aa) |
| | NCAPG2 | Non-SMC condensin II complex subunit G2. (1143 aa) |
| | SAP30 | Sin3A associated protein 30. (220 aa) |
| | REPIN1 | Replication initiator 1. (624 aa) |
| | UCHL5 | Ubiquitin carboxyl-terminal hydrolase. (368 aa) |
| | HNRNPU | Heterogeneous nuclear ribonucleoprotein U. (825 aa) |
| | POLD4 | Uncharacterized protein. (107 aa) |
| | WDHD1 | WD repeat and HMG-box DNA binding protein 1. (1126 aa) |
| | ACTR6 | Actin related protein 6; Belongs to the actin family. (428 aa) |
| | RAD21 | RAD21 cohesin complex component. (631 aa) |
| | NCAPH2 | Non-SMC condensin II complex subunit H2. (611 aa) |
| | HUS1 | Checkpoint protein; Belongs to the HUS1 family. (280 aa) |
| | TFPT | TCF3 fusion partner. (253 aa) |
| | EME2 | Essential meiotic structure-specific endonuclease subunit 2. (379 aa) |
| | LOC105571810 | Cor1 domain-containing protein. (221 aa) |
| | RGS12 | Regulator of G protein signaling 12. (1447 aa) |
| | SYCE1 | Synaptonemal complex central element protein 1. (328 aa) |
| | ENSCATP00000020493 | Uncharacterized protein. (150 aa) |
| | SIN3A | SIN3 transcription regulator family member A. (1273 aa) |
| | ENSCATP00000020093 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (433 aa) |
| | ENSCATP00000020084 | Uncharacterized protein. (191 aa) |
| | ENSCATP00000019755 | Rad21_Rec8 domain-containing protein. (141 aa) |
| | RAD51 | RAD51 recombinase; Belongs to the RecA family. (309 aa) |
| | RCC1 | Regulator of chromosome condensation 1. (461 aa) |
| | POLE4 | DNA polymerase epsilon 4, accessory subunit. (117 aa) |
| | ENSCATP00000019356 | RPA_C domain-containing protein. (276 aa) |
| | KMT2E | Lysine methyltransferase 2E. (1860 aa) |
