13 items (Cercocebus atys) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	XRCC3	DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (381 aa)
	SMC6	Structural maintenance of chromosomes 6. (1092 aa)
	ERCC1	ERCC excision repair 1, endonuclease non-catalytic subunit. (323 aa)
	SMC5	SMC_N domain-containing protein. (1201 aa)
	XRCC4	X-ray repair cross complementing 4. (334 aa)
	BRCA2	BRCA2 DNA repair associated. (3419 aa)
	RAD51	RAD51 recombinase; Belongs to the RecA family. (309 aa)
	ERCC4	ERCC excision repair 4, endonuclease catalytic subunit. (916 aa)
	ENSCATP00000020360	SP-RING-type domain-containing protein. (201 aa)
	TPRKB	TP53RK binding protein; Belongs to the CGI121/TPRKB family. (213 aa)
	TEP1	Telomerase associated protein 1. (2622 aa)
	RAD51C	RAD51 paralog C. (367 aa)
	NSMCE2	SP-RING-type domain-containing protein. (246 aa)

Your Current Organism:

Cercocebus atys

NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BRCA2	ERCC1	ENSCATP00000015406	ENSCATP00000004329	BRCA2 DNA repair associated.	ERCC excision repair 1, endonuclease non-catalytic subunit.	0.656
BRCA2	ERCC4	ENSCATP00000015406	ENSCATP00000020198	BRCA2 DNA repair associated.	ERCC excision repair 4, endonuclease catalytic subunit.	0.727
BRCA2	RAD51	ENSCATP00000015406	ENSCATP00000019738	BRCA2 DNA repair associated.	RAD51 recombinase; Belongs to the RecA family.	0.998
BRCA2	RAD51C	ENSCATP00000015406	ENSCATP00000034335	BRCA2 DNA repair associated.	RAD51 paralog C.	0.988
BRCA2	SMC5	ENSCATP00000015406	ENSCATP00000013599	BRCA2 DNA repair associated.	SMC_N domain-containing protein.	0.411
BRCA2	SMC6	ENSCATP00000015406	ENSCATP00000001620	BRCA2 DNA repair associated.	Structural maintenance of chromosomes 6.	0.401
BRCA2	XRCC3	ENSCATP00000015406	ENSCATP00000041441	BRCA2 DNA repair associated.	DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily.	0.941
BRCA2	XRCC4	ENSCATP00000015406	ENSCATP00000014934	BRCA2 DNA repair associated.	X-ray repair cross complementing 4.	0.484
ENSCATP00000020360	RAD51	ENSCATP00000020360	ENSCATP00000019738	SP-RING-type domain-containing protein.	RAD51 recombinase; Belongs to the RecA family.	0.532
ENSCATP00000020360	SMC5	ENSCATP00000020360	ENSCATP00000013599	SP-RING-type domain-containing protein.	SMC_N domain-containing protein.	0.978
ENSCATP00000020360	SMC6	ENSCATP00000020360	ENSCATP00000001620	SP-RING-type domain-containing protein.	Structural maintenance of chromosomes 6.	0.978
ERCC1	BRCA2	ENSCATP00000004329	ENSCATP00000015406	ERCC excision repair 1, endonuclease non-catalytic subunit.	BRCA2 DNA repair associated.	0.656
ERCC1	ERCC4	ENSCATP00000004329	ENSCATP00000020198	ERCC excision repair 1, endonuclease non-catalytic subunit.	ERCC excision repair 4, endonuclease catalytic subunit.	0.999
ERCC1	RAD51	ENSCATP00000004329	ENSCATP00000019738	ERCC excision repair 1, endonuclease non-catalytic subunit.	RAD51 recombinase; Belongs to the RecA family.	0.664
ERCC1	RAD51C	ENSCATP00000004329	ENSCATP00000034335	ERCC excision repair 1, endonuclease non-catalytic subunit.	RAD51 paralog C.	0.507
ERCC1	XRCC3	ENSCATP00000004329	ENSCATP00000041441	ERCC excision repair 1, endonuclease non-catalytic subunit.	DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily.	0.554
ERCC4	BRCA2	ENSCATP00000020198	ENSCATP00000015406	ERCC excision repair 4, endonuclease catalytic subunit.	BRCA2 DNA repair associated.	0.727
ERCC4	ERCC1	ENSCATP00000020198	ENSCATP00000004329	ERCC excision repair 4, endonuclease catalytic subunit.	ERCC excision repair 1, endonuclease non-catalytic subunit.	0.999
ERCC4	RAD51	ENSCATP00000020198	ENSCATP00000019738	ERCC excision repair 4, endonuclease catalytic subunit.	RAD51 recombinase; Belongs to the RecA family.	0.918
ERCC4	RAD51C	ENSCATP00000020198	ENSCATP00000034335	ERCC excision repair 4, endonuclease catalytic subunit.	RAD51 paralog C.	0.679