STRINGSTRING
SMC1A SMC1A KNL1 KNL1 PSEN1 PSEN1 DCTN6 DCTN6 NUP43 NUP43 CLASP1 CLASP1 SKA1 SKA1 PPP1CC PPP1CC ENSCATP00000034500 ENSCATP00000034500 ARID2 ARID2 CENPF CENPF BOD1L1 BOD1L1 TPR TPR MTBP MTBP MAD2L1 MAD2L1 NUP107 NUP107 SEPTIN7 SEPTIN7 ITGB3BP ITGB3BP ZNF276 ZNF276 DYNC1LI1 DYNC1LI1 ACTL6B ACTL6B PHF10 PHF10 GPATCH11 GPATCH11 DCTN2 DCTN2 CENPU CENPU NUP37 NUP37 SUGT1 SUGT1 SPOUT1 SPOUT1 CCNB1 CCNB1 NUP133 NUP133 SMARCD2 SMARCD2 ENSCATP00000040930 ENSCATP00000040930 PLK1 PLK1 KAT8 KAT8 ENSCATP00000042056 ENSCATP00000042056 PINX1 PINX1 CHMP2B CHMP2B ENSCATP00000042480 ENSCATP00000042480 CHMP4C CHMP4C ENSCATP00000042680 ENSCATP00000042680 CHMP1A CHMP1A CHMP5 CHMP5 AURKB AURKB CDT1 CDT1 CHMP4B CHMP4B PAFAH1B1 PAFAH1B1 ZWINT ZWINT NDEL1 NDEL1 AHCTF1 AHCTF1 DYNLL1 DYNLL1 BUB3 BUB3 NSL1 NSL1 CHMP3 CHMP3 CENPO CENPO MDP1 MDP1 HSF1 HSF1 FBXO28 FBXO28 SPAG5 SPAG5 KANSL1 KANSL1 CHAMP1 CHAMP1 HNRNPU HNRNPU TRAPPC12 TRAPPC12 ENSCATP00000022222 ENSCATP00000022222 SMARCE1 SMARCE1 PHF2 PHF2 DSN1 DSN1 CENPC CENPC TEX14 TEX14 SIN3A SIN3A HJURP HJURP ENSCATP00000020255 ENSCATP00000020255 SEH1L SEH1L SPDL1 SPDL1 CHMP2A CHMP2A CENPV CENPV NUP85 NUP85 SEPTIN6 SEPTIN6 RASSF2 RASSF2 ENSCATP00000025472 ENSCATP00000025472 SMARCC1 SMARCC1 KNSTRN KNSTRN BOD1L2 BOD1L2 ZWILCH ZWILCH SKA3 SKA3 ENSCATP00000027022 ENSCATP00000027022 CBX5 CBX5 INCENP INCENP MEAF6 MEAF6 MAD1L1 MAD1L1 CENPX CENPX CENPA CENPA MEIKIN MEIKIN ENSCATP00000028419 ENSCATP00000028419 CKAP5 CKAP5 PHF6 PHF6 DYNC1I1 DYNC1I1 LOC105575288 LOC105575288 ERCC6L ERCC6L CLIP1 CLIP1 ENSCATP00000029662 ENSCATP00000029662 SGO2 SGO2 PBRM1 PBRM1 MIS18BP1 MIS18BP1 MIS12 MIS12 ENSCATP00000007583 ENSCATP00000007583 CENPH CENPH DCTN1 DCTN1 CENPW CENPW CENPI CENPI ORC2 ORC2 CHMP7 CHMP7 CFDP1 CFDP1 LOC105576959 LOC105576959 CHMP6 CHMP6 ENSCATP00000003319 ENSCATP00000003319 SMARCD1 SMARCD1 RSKR RSKR ENSCATP00000002218 ENSCATP00000002218 NDE1 NDE1 NUF2 NUF2 NEK2 NEK2 CENPK CENPK BOD1 BOD1 ENSCATP00000001118 ENSCATP00000001118 RANGAP1 RANGAP1 BUB1 BUB1 FBXW11 FBXW11 NUDCD2 NUDCD2 ANAPC16 ANAPC16 SPC25 SPC25 CENPM CENPM ZW10 ZW10 DYNLT3 DYNLT3 SMARCB1 SMARCB1 PMF1 PMF1 DCTN5 DCTN5 ENSCATP00000009181 ENSCATP00000009181 BUB1B BUB1B CENPN CENPN KAT2B KAT2B TP53BP1 TP53BP1 SMARCC2 SMARCC2 XPO1 XPO1 ENSCATP00000016773 ENSCATP00000016773 BIRC5 BIRC5 ZNF207 ZNF207 SGO1 SGO1 RASSF4 RASSF4 SKA2 SKA2 KIF2C KIF2C CENPT CENPT LRWD1 LRWD1 KIF18A KIF18A ENSCATP00000014343 ENSCATP00000014343 APC APC SMARCA4 SMARCA4 NDC80 NDC80 TTK TTK SS18L1 SS18L1 SPC24 SPC24 REC8 REC8 DCTN3 DCTN3 KNTC1 KNTC1 PPP1R12A PPP1R12A KAT5 KAT5 CENPE CENPE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SMC1AStructural maintenance of chromosomes protein. (1233 aa)
KNL1Kinetochore scaffold 1. (2303 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
DCTN6Dynactin subunit 6. (192 aa)
NUP43WD_REPEATS_REGION domain-containing protein. (380 aa)
CLASP1Cytoplasmic linker associated protein 1. (1533 aa)
SKA1Spindle and kinetochore associated complex subunit 1. (255 aa)
PPP1CCSerine/threonine-protein phosphatase. (293 aa)
ENSCATP00000034500Uncharacterized protein. (464 aa)
ARID2AT-rich interaction domain 2. (1836 aa)
CENPFCentromere protein F. (3113 aa)
BOD1L1Biorientation of chromosomes in cell division 1 like 1. (2979 aa)
TPRTranslocated promoter region, nuclear basket protein. (2439 aa)
MTBPMDM2 binding protein. (904 aa)
MAD2L1HORMA domain-containing protein. (206 aa)
NUP107Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (925 aa)
SEPTIN7Septin 7; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (429 aa)
ITGB3BPIntegrin subunit beta 3 binding protein. (216 aa)
ZNF276Zinc finger protein 276. (613 aa)
DYNC1LI1Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (523 aa)
ACTL6BActin like 6B; Belongs to the actin family. (426 aa)
PHF10PHD finger protein 10. (410 aa)
GPATCH11G-patch domain containing 11. (263 aa)
DCTN2Dynactin subunit 2. (427 aa)
CENPUCentromere protein U. (419 aa)
NUP37Nucleoporin 37. (326 aa)
SUGT1SGT1 homolog, MIS12 kinetochore complex assembly cochaperone. (363 aa)
SPOUT1SPOUT domain containing methyltransferase 1. (376 aa)
CCNB1Cyclin B1; Belongs to the cyclin family. (433 aa)
NUP133Nucleoporin 133. (1156 aa)
SMARCD2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2. (531 aa)
ENSCATP00000040930GFA domain-containing protein. (287 aa)
PLK1Serine/threonine-protein kinase PLK. (603 aa)
KAT8Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (467 aa)
ENSCATP00000042056Dynein light chain. (74 aa)
PINX1PIN2 (TERF1) interacting telomerase inhibitor 1. (322 aa)
CHMP2BCharged multivesicular body protein 2B. (213 aa)
ENSCATP00000042480Uncharacterized protein. (159 aa)
CHMP4CCharged multivesicular body protein 4C. (233 aa)
ENSCATP00000042680Uncharacterized protein. (400 aa)
CHMP1ACharged multivesicular body protein 1A. (196 aa)
CHMP5Charged multivesicular body protein 5. (219 aa)
AURKBAurora kinase B; Belongs to the protein kinase superfamily. (344 aa)
CDT1Chromatin licensing and DNA replication factor 1. (545 aa)
CHMP4BCharged multivesicular body protein 4B. (224 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (410 aa)
ZWINTZW10 interacting kinetochore protein. (277 aa)
NDEL1NudE neurodevelopment protein 1 like 1. (345 aa)
AHCTF1AT-hook containing transcription factor 1. (2299 aa)
DYNLL1Dynein light chain. (89 aa)
BUB3WD_REPEATS_REGION domain-containing protein. (328 aa)
NSL1NSL1 component of MIS12 kinetochore complex. (281 aa)
CHMP3Charged multivesicular body protein 3. (221 aa)
CENPOCentromere protein O. (299 aa)
MDP1Magnesium dependent phosphatase 1. (164 aa)
HSF1Heat shock transcription factor 1. (532 aa)
FBXO28F-box protein 28. (368 aa)
SPAG5Sperm associated antigen 5. (1194 aa)
KANSL1KAT8 regulatory NSL complex subunit 1. (744 aa)
CHAMP1Chromosome alignment maintaining phosphoprotein 1. (688 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U. (825 aa)
TRAPPC12Trafficking protein particle complex 12. (741 aa)
ENSCATP00000022222Uncharacterized protein. (164 aa)
SMARCE1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1. (411 aa)
PHF2PHD finger protein 2. (1083 aa)
DSN1DSN1 component of MIS12 kinetochore complex. (354 aa)
CENPCCentromere protein C. (945 aa)
TEX14Testis expressed 14, intercellular bridge forming factor. (1497 aa)
SIN3ASIN3 transcription regulator family member A. (1273 aa)
HJURPHolliday junction recognition protein. (728 aa)
ENSCATP00000020255Dynein light chain. (83 aa)
SEH1LSEH1 like nucleoporin; Belongs to the WD repeat SEC13 family. (367 aa)
SPDL1Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. (605 aa)
CHMP2ACharged multivesicular body protein 2A. (222 aa)
CENPVCentromere protein V. (274 aa)
NUP85Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (656 aa)
SEPTIN6Septin 6; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (434 aa)
RASSF2Ras association domain family member 2. (326 aa)
ENSCATP00000025472Uncharacterized protein. (122 aa)
SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1. (1105 aa)
KNSTRNKinetochore localized astrin (SPAG5) binding protein. (316 aa)
BOD1L2Biorientation of chromosomes in cell division 1 like 2. (171 aa)
ZWILCHZwilch kinetochore protein. (591 aa)
SKA3Spindle and kinetochore associated complex subunit 3. (397 aa)
ENSCATP00000027022HORMA domain-containing protein. (162 aa)
CBX5Chromobox 5. (191 aa)
INCENPInner centromere protein. (768 aa)
MEAF6Uncharacterized protein. (201 aa)
MAD1L1Mitotic arrest deficient 1 like 1. (718 aa)
CENPXCentromere protein X. (133 aa)
CENPACentromere protein A. (138 aa)
MEIKINMeiotic kinetochore factor. (374 aa)
ENSCATP00000028419Uncharacterized protein. (270 aa)
CKAP5Cytoskeleton associated protein 5. (2032 aa)
PHF6PHD finger protein 6. (366 aa)
DYNC1I1Dynein cytoplasmic 1 intermediate chain 1. (628 aa)
LOC105575288Uncharacterized protein. (1383 aa)
ERCC6LERCC excision repair 6 like, spindle assembly checkpoint helicase. (1252 aa)
CLIP1CAP-Gly domain containing linker protein 1. (1438 aa)
ENSCATP00000029662Uncharacterized protein. (305 aa)
SGO2Shugoshin 2. (1260 aa)
PBRM1Polybromo 1. (1725 aa)
MIS18BP1MIS18 binding protein 1. (1131 aa)
MIS12Uncharacterized protein. (205 aa)
ENSCATP00000007583Uncharacterized protein. (188 aa)
CENPHCentromere protein H. (247 aa)
DCTN1CAP-Gly domain-containing protein. (1278 aa)
CENPWCentromere protein W. (103 aa)
CENPICentromere protein I. (755 aa)
ORC2Origin recognition complex subunit 2. (577 aa)
CHMP7Charged multivesicular body protein 7. (453 aa)
CFDP1Craniofacial development protein 1; May play a role during embryogenesis. (299 aa)
LOC105576959Uncharacterized protein. (200 aa)
CHMP6Charged multivesicular body protein 6. (214 aa)
ENSCATP00000003319Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (419 aa)
SMARCD1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1. (515 aa)
RSKRRibosomal protein S6 kinase related. (402 aa)
ENSCATP00000002218Uncharacterized protein. (228 aa)
NDE1NudE neurodevelopment protein 1. (368 aa)
NUF2NUF2 component of NDC80 kinetochore complex. (450 aa)
NEK2NIMA related kinase 2. (445 aa)
CENPKCentromere protein K. (269 aa)
BOD1Uncharacterized protein. (185 aa)
ENSCATP00000001118WD_REPEATS_REGION domain-containing protein. (357 aa)
RANGAP1Ran GTPase activating protein 1. (627 aa)
BUB1BUB1 mitotic checkpoint serine/threonine kinase. (1096 aa)
FBXW11F-box and WD repeat domain containing 11. (563 aa)
NUDCD2NudC domain containing 2. (155 aa)
ANAPC16Anaphase promoting complex subunit 16. (110 aa)
SPC25SPC25 component of NDC80 kinetochore complex. (235 aa)
CENPMCentromere protein M. (180 aa)
ZW10Zw10 kinetochore protein. (778 aa)
DYNLT3Uncharacterized protein. (151 aa)
SMARCB1SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (385 aa)
PMF1Polyamine modulated factor 1. (205 aa)
DCTN5Dynactin subunit 5. (182 aa)
ENSCATP00000009181HMG box domain-containing protein. (177 aa)
BUB1BBUB1 N-terminal domain-containing protein. (1073 aa)
CENPNCentromere protein N. (293 aa)
KAT2BHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (832 aa)
TP53BP1Tumor protein p53 binding protein 1. (1979 aa)
SMARCC2SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2. (1271 aa)
XPO1Exportin 1. (1070 aa)
ENSCATP00000016773Uncharacterized protein. (304 aa)
BIRC5Uncharacterized protein. (147 aa)
ZNF207Zinc finger protein 207. (496 aa)
SGO1Shugoshin 1. (527 aa)
RASSF4Ras association domain family member 4. (321 aa)
SKA2SKA2 domain-containing protein. (121 aa)
KIF2CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (729 aa)
CENPTCentromere protein T. (561 aa)
LRWD1Leucine rich repeats and WD repeat domain containing 1. (647 aa)
KIF18AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (897 aa)
ENSCATP00000014343SKA2 domain-containing protein. (111 aa)
APCAPC regulator of WNT signaling pathway. (2861 aa)
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1679 aa)
NDC80NDC80 kinetochore complex component. (580 aa)
TTKTTK protein kinase. (857 aa)
SS18L1SS18L1 subunit of BAF chromatin remodeling complex. (314 aa)
SPC24Uncharacterized protein. (133 aa)
REC8REC8 meiotic recombination protein. (549 aa)
DCTN3Dynactin subunit 3. (186 aa)
KNTC1Kinetochore associated 1. (2199 aa)
PPP1R12AProtein phosphatase 1 regulatory subunit. (1029 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (537 aa)
CENPECentromere protein E; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2701 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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