STRINGSTRING
MEI4 MEI4 BRCA1 BRCA1 SMC3 SMC3 SYCP3 SYCP3 SMC1B SMC1B BLM BLM REC8 REC8 INCENP INCENP STAG3 STAG3 LOC105571810 LOC105571810 RAD51 RAD51 BRCA2 BRCA2 CCDC155 CCDC155 SYCP2L SYCP2L SYCP2 SYCP2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MEI4Meiotic double-stranded break formation protein 4. (384 aa)
BRCA1Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1871 aa)
SMC3Structural maintenance of chromosomes 3. (1007 aa)
SYCP3Cor1 domain-containing protein. (236 aa)
SMC1BStructural maintenance of chromosomes protein. (1235 aa)
BLMBLM RecQ like helicase. (1416 aa)
REC8REC8 meiotic recombination protein. (549 aa)
INCENPInner centromere protein. (768 aa)
STAG3Stromal antigen 3. (1268 aa)
LOC105571810Cor1 domain-containing protein. (221 aa)
RAD51RAD51 recombinase; Belongs to the RecA family. (309 aa)
BRCA2BRCA2 DNA repair associated. (3419 aa)
CCDC155Coiled-coil domain containing 155. (562 aa)
SYCP2LSynaptonemal complex protein 2 like. (787 aa)
SYCP2Synaptonemal complex protein 2. (1530 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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