STRINGSTRING
BOD1 BOD1 CEP63 CEP63 SMC6 SMC6 NEK2 NEK2 NDE1 NDE1 KATNBL1 KATNBL1 GOLGA2 GOLGA2 PPP2CB PPP2CB RSKR RSKR NPM1 NPM1 ABRAXAS2 ABRAXAS2 ENSCATP00000003984 ENSCATP00000003984 VPS4A VPS4A RMDN1 RMDN1 CNTRL CNTRL BEX4 BEX4 CETN1 CETN1 LATS1 LATS1 PRC1 PRC1 DCTN1 DCTN1 AUNIP AUNIP ODF2 ODF2 UXT UXT HAUS8 HAUS8 BRCC3 BRCC3 POC1A POC1A FAM110A FAM110A BCCIP BCCIP RASSF10 RASSF10 NEK7 NEK7 ANKRD53 ANKRD53 MAPKBP1 MAPKBP1 HAUS1 HAUS1 CDC20 CDC20 ENSCATP00000009362 ENSCATP00000009362 CDK5RAP2 CDK5RAP2 TACC3 TACC3 RAE1 RAE1 STAG2 STAG2 MISP MISP NEDD9 NEDD9 DDX11 DDX11 ZW10 ZW10 NIN NIN IKBKG IKBKG GIT1 GIT1 CDC6 CDC6 TMEM201 TMEM201 WDR73 WDR73 CCDC155 CCDC155 PLK5 PLK5 SGO1 SGO1 CDC14A CDC14A CDC14C CDC14C CEP44 CEP44 CTDP1 CTDP1 DNAAF1 DNAAF1 NUBP2 NUBP2 CEP89 CEP89 TUBGCP4 TUBGCP4 KATNB1 KATNB1 UNC119 UNC119 ENSCATP00000018692 ENSCATP00000018692 AURKA AURKA TPX2 TPX2 SPDL1 SPDL1 ENSCATP00000019755 ENSCATP00000019755 CDC25B CDC25B CEP85 CEP85 CALM2 CALM2 EML1 EML1 FRY FRY UMOD UMOD CTNNB1 CTNNB1 CEP128 CEP128 ENSCATP00000022222 ENSCATP00000022222 EFCAB3 EFCAB3 ARHGEF7 ARHGEF7 YPEL5 YPEL5 RAD21 RAD21 HNRNPU HNRNPU CEP95 CEP95 KLHL22 KLHL22 SPAG5 SPAG5 HSF1 HSF1 TUBGCP5 TUBGCP5 STAG1 STAG1 CSPP1 CSPP1 KATNAL1 KATNAL1 WDR62 WDR62 POC1B POC1B KNSTRN KNSTRN PLEKHG6 PLEKHG6 BOD1L2 BOD1L2 KIF20B KIF20B UBXN2B UBXN2B CALM3 CALM3 ENSCATP00000026830 ENSCATP00000026830 RMDN2 RMDN2 TUBGCP2 TUBGCP2 ENSCATP00000027022 ENSCATP00000027022 KATNAL2 KATNAL2 MAD1L1 MAD1L1 CDC14B CDC14B PSRC1 PSRC1 KATNA1 KATNA1 TNKS TNKS CKAP5 CKAP5 DYNC1I1 DYNC1I1 ENSCATP00000029460 ENSCATP00000029460 NUDCD2 NUDCD2 KNTC1 KNTC1 EFHC1 EFHC1 KAT5 KAT5 GPSM2 GPSM2 SMC1A SMC1A ALPK1 ALPK1 ENSCATP00000031513 ENSCATP00000031513 MTCL1 MTCL1 SBDS SBDS CUL3 CUL3 ENSCATP00000032242 ENSCATP00000032242 RALBP1 RALBP1 LOC105573813 LOC105573813 CALM1 CALM1 PPP2CA PPP2CA TUBGCP3 TUBGCP3 LATS2 LATS2 ENSCATP00000045875 ENSCATP00000045875 DLGAP5 DLGAP5 KIF11 KIF11 CENPF CENPF FBF1 FBF1 BOD1L1 BOD1L1 NEDD1 NEDD1 MAD2L1 MAD2L1 ENSCATP00000035826 ENSCATP00000035826 ENSCATP00000035908 ENSCATP00000035908 AURKC AURKC TOPORS TOPORS CEP19 CEP19 PLK3 PLK3 KLHL21 KLHL21 DYNC1LI1 DYNC1LI1 LOC105575645 LOC105575645 MAPRE1 MAPRE1 MAPK14 MAPK14 ENSCATP00000038940 ENSCATP00000038940 ENSCATP00000039241 ENSCATP00000039241 ENSCATP00000039328 ENSCATP00000039328 FAM110C FAM110C ENSCATP00000040020 ENSCATP00000040020 RASSF1 RASSF1 SPOUT1 SPOUT1 CCNB1 CCNB1 LOC105600316 LOC105600316 ENSCATP00000040578 ENSCATP00000040578 PKP4 PKP4 ALMS1 ALMS1 PLK1 PLK1 RGS14 RGS14 ASPM ASPM AAAS AAAS NUP62 NUP62 FAM161A FAM161A AURKB AURKB SMC3 SMC3 IK IK ENSCATP00000043586 ENSCATP00000043586 NEK6 NEK6 RMDN3 RMDN3 BIRC6 BIRC6 TBCCD1 TBCCD1 NUMA1 NUMA1 CEP104 CEP104 ENSCATP00000045213 ENSCATP00000045213 EFCAB13 EFCAB13 TOPBP1 TOPBP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BOD1Uncharacterized protein. (185 aa)
CEP63Centrosomal protein 63. (703 aa)
SMC6Structural maintenance of chromosomes 6. (1092 aa)
NEK2NIMA related kinase 2. (445 aa)
NDE1NudE neurodevelopment protein 1. (368 aa)
KATNBL1Katanin regulatory subunit B1 like 1. (304 aa)
GOLGA2Golgin A2. (1005 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
RSKRRibosomal protein S6 kinase related. (402 aa)
NPM1Nucleophosmin 1. (294 aa)
ABRAXAS2Abraxas 2, BRISC complex subunit. (404 aa)
ENSCATP00000003984Uncharacterized protein. (276 aa)
VPS4AUncharacterized protein; Belongs to the AAA ATPase family. (501 aa)
RMDN1Regulator of microtubule dynamics 1. (314 aa)
CNTRLCentriolin. (2325 aa)
BEX4Brain expressed X-linked 4. (120 aa)
CETN1Centrin 1. (172 aa)
LATS1Large tumor suppressor kinase 1. (1179 aa)
PRC1Protein regulator of cytokinesis 1. (620 aa)
DCTN1CAP-Gly domain-containing protein. (1278 aa)
AUNIPAurora kinase A and ninein interacting protein. (351 aa)
ODF2Outer dense fiber of sperm tails 2. (829 aa)
UXTUbiquitously expressed prefoldin like chaperone. (157 aa)
HAUS8HAUS augmin like complex subunit 8. (381 aa)
BRCC3MPN domain-containing protein. (293 aa)
POC1APOC1 centriolar protein A. (407 aa)
FAM110AFamily with sequence similarity 110 member A. (295 aa)
BCCIPBRCA2 and CDKN1A interacting protein. (324 aa)
RASSF10Ras association domain family member 10. (508 aa)
NEK7NIMA related kinase 7; Belongs to the protein kinase superfamily. (302 aa)
ANKRD53Ankyrin repeat domain 53. (530 aa)
MAPKBP1Mitogen-activated protein kinase binding protein 1. (1514 aa)
HAUS1HAUS augmin like complex subunit 1. (278 aa)
CDC20Cell division cycle 20. (499 aa)
ENSCATP00000009362BRCA2 and CDKN1A-interacting protein; May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ); Belongs to the BCP1 family. (293 aa)
CDK5RAP2CDK5 regulatory subunit associated protein 2. (1924 aa)
TACC3Transforming acidic coiled-coil containing protein 3. (817 aa)
RAE1Ribonucleic acid export 1. (368 aa)
STAG2Stromal antigen 2. (1268 aa)
MISPMitotic spindle positioning. (679 aa)
NEDD9Neural precursor cell expressed, developmentally down-regulated 9. (839 aa)
DDX11DEAD/H-box helicase 11. (918 aa)
ZW10Zw10 kinetochore protein. (778 aa)
NINNinein. (2133 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (419 aa)
GIT1GIT ArfGAP 1. (770 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (599 aa)
TMEM201Transmembrane protein 201. (667 aa)
WDR73WD repeat domain 73. (372 aa)
CCDC155Coiled-coil domain containing 155. (562 aa)
PLK5Polo like kinase 5. (336 aa)
SGO1Shugoshin 1. (527 aa)
CDC14ACell division cycle 14A. (595 aa)
CDC14CCell division cycle 14C. (586 aa)
CEP44Centrosomal protein 44. (399 aa)
CTDP1RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (964 aa)
DNAAF1Dynein assembly factor 1, axonemal. (612 aa)
NUBP2Cytosolic Fe-S cluster assembly factor NUBP2; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily. (271 aa)
CEP89Centrosomal protein 89. (753 aa)
TUBGCP4Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (667 aa)
KATNB1Katanin p80 WD40 repeat-containing subunit B1; Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Micr [...] (655 aa)
UNC119Unc-119 lipid binding chaperone. (240 aa)
ENSCATP00000018692MPN domain-containing protein. (273 aa)
AURKAProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (403 aa)
TPX2TPX2 microtubule nucleation factor. (747 aa)
SPDL1Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. (605 aa)
ENSCATP00000019755Rad21_Rec8 domain-containing protein. (141 aa)
CDC25BCell division cycle 25B. (580 aa)
CEP85Centrosomal protein 85. (762 aa)
CALM2Calmodulin 1; Belongs to the calmodulin family. (149 aa)
EML1EMAP like 1. (853 aa)
FRYFRY microtubule binding protein. (2990 aa)
UMODUromodulin. (674 aa)
CTNNB1Catenin beta 1. (781 aa)
CEP128Centrosomal protein 128. (1095 aa)
ENSCATP00000022222Uncharacterized protein. (164 aa)
EFCAB3EF-hand calcium binding domain 3. (470 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7. (804 aa)
YPEL5Protein yippee-like; Belongs to the yippee family. (121 aa)
RAD21RAD21 cohesin complex component. (631 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U. (825 aa)
CEP95Centrosomal protein 95. (821 aa)
KLHL22Kelch like family member 22. (634 aa)
SPAG5Sperm associated antigen 5. (1194 aa)
HSF1Heat shock transcription factor 1. (532 aa)
TUBGCP5Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (1024 aa)
STAG1Stromal antigen 1. (1291 aa)
CSPP1Centrosome and spindle pole associated protein 1. (1212 aa)
KATNAL1Katanin p60 ATPase-containing subunit A-like 1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neur [...] (490 aa)
WDR62WD repeat domain 62. (1523 aa)
POC1BPOC1 centriolar protein B. (480 aa)
KNSTRNKinetochore localized astrin (SPAG5) binding protein. (316 aa)
PLEKHG6Pleckstrin homology and RhoGEF domain containing G6. (790 aa)
BOD1L2Biorientation of chromosomes in cell division 1 like 2. (171 aa)
KIF20BKinesin family member 20B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1823 aa)
UBXN2BUBX domain protein 2B. (331 aa)
CALM3Calmodulin 3. (149 aa)
ENSCATP00000026830Uncharacterized protein. (233 aa)
RMDN2Regulator of microtubule dynamics 2. (573 aa)
TUBGCP2Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (902 aa)
ENSCATP00000027022HORMA domain-containing protein. (162 aa)
KATNAL2Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. (538 aa)
MAD1L1Mitotic arrest deficient 1 like 1. (718 aa)
CDC14BCell division cycle 14B. (498 aa)
PSRC1Proline and serine rich coiled-coil 1. (362 aa)
KATNA1Katanin catalytic subunit A1; Belongs to the AAA ATPase family. (322 aa)
TNKSPoly [ADP-ribose] polymerase. (1327 aa)
CKAP5Cytoskeleton associated protein 5. (2032 aa)
DYNC1I1Dynein cytoplasmic 1 intermediate chain 1. (628 aa)
ENSCATP00000029460Uncharacterized protein. (124 aa)
NUDCD2NudC domain containing 2. (155 aa)
KNTC1Kinetochore associated 1. (2199 aa)
EFHC1EF-hand domain containing 1. (641 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (537 aa)
GPSM2G protein signaling modulator 2. (685 aa)
SMC1AStructural maintenance of chromosomes protein. (1233 aa)
ALPK1Alpha kinase 1. (1244 aa)
ENSCATP00000031513Uncharacterized protein. (295 aa)
MTCL1Microtubule crosslinking factor 1. (1906 aa)
SBDSSBDS ribosome maturation factor. (250 aa)
CUL3Cullin 3; Belongs to the cullin family. (768 aa)
ENSCATP00000032242Uncharacterized protein; Belongs to the calmodulin family. (128 aa)
RALBP1RalA binding protein 1. (655 aa)
LOC105573813Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (394 aa)
CALM1Calmodulin 1. (149 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
TUBGCP3Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (887 aa)
LATS2Non-specific serine/threonine protein kinase. (1086 aa)
ENSCATP00000045875Rho-GAP domain-containing protein. (525 aa)
DLGAP5DLG associated protein 5. (851 aa)
KIF11Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1056 aa)
CENPFCentromere protein F. (3113 aa)
FBF1Fas binding factor 1. (1132 aa)
BOD1L1Biorientation of chromosomes in cell division 1 like 1. (2979 aa)
NEDD1NEDD1 gamma-tubulin ring complex targeting factor. (661 aa)
MAD2L1HORMA domain-containing protein. (206 aa)
ENSCATP00000035826Uncharacterized protein. (286 aa)
ENSCATP00000035908Uncharacterized protein. (247 aa)
AURKCAurora kinase C; Belongs to the protein kinase superfamily. (309 aa)
TOPORSTOP1 binding arginine/serine rich protein. (1085 aa)
CEP19Centrosomal protein 19. (167 aa)
PLK3Serine/threonine-protein kinase PLK. (673 aa)
KLHL21Kelch like family member 21. (597 aa)
DYNC1LI1Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (523 aa)
LOC105575645Nucleoplasmin domain-containing protein. (210 aa)
MAPRE1Microtubule associated protein RP/EB family member 1. (268 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
ENSCATP00000038940Uncharacterized protein. (566 aa)
ENSCATP00000039241Uncharacterized protein. (287 aa)
ENSCATP00000039328Nucleoplasmin domain-containing protein. (209 aa)
FAM110CFamily with sequence similarity 110 member C. (320 aa)
ENSCATP00000040020Uncharacterized protein; Belongs to the calmodulin family. (91 aa)
RASSF1Ras association domain family member 1. (340 aa)
SPOUT1SPOUT domain containing methyltransferase 1. (376 aa)
CCNB1Cyclin B1; Belongs to the cyclin family. (433 aa)
LOC105600316Uncharacterized protein. (702 aa)
ENSCATP00000040578Nucleoplasmin domain-containing protein. (217 aa)
PKP4Plakophilin 4. (1190 aa)
ALMS1ALMS1 centrosome and basal body associated protein. (4262 aa)
PLK1Serine/threonine-protein kinase PLK. (603 aa)
RGS14Regulator of G protein signaling 14. (592 aa)
ASPMAbnormal spindle microtubule assembly. (3476 aa)
AAASAladin WD repeat nucleoporin. (546 aa)
NUP62Nucleoporin 62. (338 aa)
FAM161AFAM161 centrosomal protein A. (714 aa)
AURKBAurora kinase B; Belongs to the protein kinase superfamily. (344 aa)
SMC3Structural maintenance of chromosomes 3. (1007 aa)
IKIK cytokine. (557 aa)
ENSCATP00000043586Uncharacterized protein; Belongs to the calmodulin family. (128 aa)
NEK6NIMA related kinase 6; Belongs to the protein kinase superfamily. (347 aa)
RMDN3Regulator of microtubule dynamics 3. (471 aa)
BIRC6Baculoviral IAP repeat containing 6. (4890 aa)
TBCCD1TBCC domain containing 1. (557 aa)
NUMA1Nuclear mitotic apparatus protein 1. (2098 aa)
CEP104Centrosomal protein 104. (925 aa)
ENSCATP00000045213Uncharacterized protein. (170 aa)
EFCAB13EF-hand calcium binding domain 13. (972 aa)
TOPBP1DNA topoisomerase II binding protein 1. (1527 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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