STRINGSTRING
PARP4 PARP4 TNKS TNKS PARP1 PARP1 PARP15 PARP15 SIRT6 SIRT6 ZC3HAV1 ZC3HAV1 VWA5A VWA5A VWA5B2 VWA5B2 ANKRD39 ANKRD39 SIRT3 SIRT3 PARP6 PARP6 ART5 ART5 ART3 ART3 PARP2 PARP2 ART1 ART1 PARP10 PARP10 PARP3 PARP3 PARP12 PARP12 PARP8 PARP8 VWA5B1 VWA5B1 PARP16 PARP16 TIPARP TIPARP ART4 ART4 FAM162B FAM162B FAM162A FAM162A PARP9 PARP9 PARP14 PARP14 SIRT4 SIRT4 TNKS2 TNKS2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PARP4Poly [ADP-ribose] polymerase. (1677 aa)
TNKSPoly [ADP-ribose] polymerase. (1327 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa)
PARP15Poly [ADP-ribose] polymerase. (663 aa)
SIRT6Sirtuin 6. (355 aa)
ZC3HAV1Zinc finger CCCH-type containing, antiviral 1. (1027 aa)
VWA5AVon Willebrand factor A domain containing 5A. (786 aa)
VWA5B2Von Willebrand factor A domain containing 5B2. (1243 aa)
ANKRD39Ankyrin repeat domain 39. (183 aa)
SIRT3NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (399 aa)
PARP6Poly [ADP-ribose] polymerase. (631 aa)
ART5NAD(P)(+)--arginine ADP-ribosyltransferase. (291 aa)
ART3NAD(P)(+)--arginine ADP-ribosyltransferase. (390 aa)
PARP2Poly [ADP-ribose] polymerase. (581 aa)
ART1NAD(P)(+)--arginine ADP-ribosyltransferase. (327 aa)
PARP10Poly [ADP-ribose] polymerase. (1025 aa)
PARP3Poly [ADP-ribose] polymerase. (539 aa)
PARP12Poly(ADP-ribose) polymerase family member 12. (701 aa)
PARP8Poly [ADP-ribose] polymerase. (894 aa)
VWA5B1Von Willebrand factor A domain containing 5B1. (1215 aa)
PARP16Poly [ADP-ribose] polymerase. (322 aa)
TIPARPTCDD inducible poly(ADP-ribose) polymerase. (657 aa)
ART4NAD(P)(+)--arginine ADP-ribosyltransferase. (337 aa)
FAM162BFamily with sequence similarity 162 member B. (162 aa)
FAM162AFamily with sequence similarity 162 member A. (155 aa)
PARP9Poly(ADP-ribose) polymerase family member 9. (823 aa)
PARP14Poly [ADP-ribose] polymerase. (1800 aa)
SIRT4NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] (314 aa)
TNKS2Poly [ADP-ribose] polymerase. (1315 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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