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FMO4 FMO4 MSMO1 MSMO1 MICAL3 MICAL3 CYP4V2 CYP4V2 LOC105599024 LOC105599024 FMO1 FMO1 LOC105579288 LOC105579288 LOC105598000 LOC105598000 ENSCATP00000013840 ENSCATP00000013840 TTI2 TTI2 CYP21A2 CYP21A2 COQ7 COQ7 LOC105575617 LOC105575617 LOC105597997 LOC105597997 LOC105575618 LOC105575618 CYP4F22 CYP4F22 DOHH DOHH MICAL2 MICAL2 TYRP1 TYRP1 HMOX1 HMOX1 LOC105601614 LOC105601614 ENSCATP00000042502 ENSCATP00000042502 CYP24A1 CYP24A1 LOC105572634 LOC105572634 YWHAH YWHAH LOC105601618 LOC105601618 CYP27B1 CYP27B1 CCNDBP1 CCNDBP1 CYP2W1 CYP2W1 FOXRED2 FOXRED2 CYP4F8 CYP4F8 LOC105597444 LOC105597444 CYP17A1 CYP17A1 CYP11A1 CYP11A1 FMO5 FMO5 ENSCATP00000036069 ENSCATP00000036069 PAH PAH NOS3 NOS3 CYP2J2 CYP2J2 CYP2B6 CYP2B6 CYP2C18 CYP2C18 TPH1 TPH1 AKR1D1 AKR1D1 CYP2R1 CYP2R1 LOC105598006 LOC105598006 LOC105597447 LOC105597447 CYP26C1 CYP26C1 CYP2S1 CYP2S1 NOS1 NOS1 MOXD1 MOXD1 LOC105597998 LOC105597998 LOC105601617 LOC105601617 CYP4X1 CYP4X1 KMO KMO LOC105571706 LOC105571706 HMOX2 HMOX2 CYP7B1 CYP7B1 TPH2 TPH2 LOC105601619 LOC105601619 LOC105573227 LOC105573227 LOC105584398 LOC105584398 CYP1A1 CYP1A1 CYP8B1 CYP8B1 CYP7A1 CYP7A1 LOC105586938 LOC105586938 CYP4B1 CYP4B1 KLKB1 KLKB1 CYP2U1 CYP2U1 CYP2F1 CYP2F1 LOC105581754 LOC105581754 NOS2 NOS2 CYP1A2 CYP1A2 CYP39A1 CYP39A1 CYP26B1 CYP26B1 CYP20A1 CYP20A1 FMO2 FMO2 PCBD1 PCBD1 AGMO AGMO TH TH JMJD7 JMJD7 SQLE SQLE LOC105581138 LOC105581138 LOC105601616 LOC105601616 CYP4Z1 CYP4Z1 CYP3A43 CYP3A43 ENSCATP00000018702 ENSCATP00000018702 LOC105576140 LOC105576140 MICAL1 MICAL1 CYP11B1 CYP11B1 FMO3 FMO3 ENSCATP00000000248 ENSCATP00000000248 FMO3-2 FMO3-2 NLRP11 NLRP11 TYR TYR LOC105598973 LOC105598973 LOC105572143 LOC105572143 LOC105598002 LOC105598002 TBXAS1 TBXAS1 LOC105587688 LOC105587688 CYP46A1 CYP46A1 LOC105587685 LOC105587685 PTGIS PTGIS PAM PAM CYP1B1 CYP1B1 DBH DBH LOC105581294 LOC105581294 COQ6 COQ6 LOC105584179 LOC105584179 CYP4F11 CYP4F11 CYP27A1 CYP27A1 LOC105576141 LOC105576141 CYP51A1 CYP51A1 CYP19A1 CYP19A1 SAAL1 SAAL1 MIOX MIOX AKR1C3 AKR1C3 PCBD2 PCBD2 CYP27C1 CYP27C1
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
FMO4Dimethylaniline monooxygenase [N-oxide-forming]. (558 aa)
MSMO1Methylsterol monooxygenase 1; Belongs to the sterol desaturase family. (293 aa)
MICAL3Microtubule associated monooxygenase, calponin and LIM domain containing 3. (2001 aa)
CYP4V2Cytochrome P450 family 4 subfamily V member 2; Belongs to the cytochrome P450 family. (525 aa)
LOC105599024Uncharacterized protein. (268 aa)
FMO1Dimethylaniline monooxygenase [N-oxide-forming]. (532 aa)
LOC105579288Uncharacterized protein; Belongs to the cytochrome P450 family. (217 aa)
LOC105598000Uncharacterized protein; Belongs to the cytochrome P450 family. (494 aa)
ENSCATP00000013840Aldo_ket_red domain-containing protein. (256 aa)
TTI2TELO2 interacting protein 2. (483 aa)
CYP21A2Cytochrome P450 family 21 subfamily A member 2; Belongs to the cytochrome P450 family. (399 aa)
COQ75-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone- independent manner. (217 aa)
LOC105575617Uncharacterized protein. (164 aa)
LOC105597997Uncharacterized protein; Belongs to the cytochrome P450 family. (494 aa)
LOC105575618Uncharacterized protein; Belongs to the cytochrome P450 family. (490 aa)
CYP4F22Cytochrome P450 family 4 subfamily F member 22; Belongs to the cytochrome P450 family. (531 aa)
DOHHDeoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor; Belongs to the deoxyhypusine hydroxylase family. (315 aa)
MICAL2Microtubule associated monooxygenase, calponin and LIM domain containing 2. (1124 aa)
TYRP1Tyrosinase related protein 1. (537 aa)
HMOX1Heme oxygenase 1. (311 aa)
LOC105601614Uncharacterized protein; Belongs to the cytochrome P450 family. (520 aa)
ENSCATP00000042502Uncharacterized protein; Belongs to the cytochrome P450 family. (480 aa)
CYP24A1Cytochrome P450 family 24 subfamily A member 1; Belongs to the cytochrome P450 family. (514 aa)
LOC105572634Rieske domain-containing protein. (613 aa)
YWHAHTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; Belongs to the 14-3-3 family. (246 aa)
LOC105601618Uncharacterized protein; Belongs to the cytochrome P450 family. (524 aa)
CYP27B1Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (508 aa)
CCNDBP1Cyclin D1 binding protein 1. (360 aa)
CYP2W1Cytochrome P450 family 2 subfamily W member 1; Belongs to the cytochrome P450 family. (512 aa)
FOXRED2FAD dependent oxidoreductase domain containing 2. (684 aa)
CYP4F8Cytochrome P450 family 4 subfamily F member 8; Belongs to the cytochrome P450 family. (520 aa)
LOC105597444Aldo_ket_red domain-containing protein. (267 aa)
CYP17A1Cytochrome P450 family 17 subfamily A member 1; Belongs to the cytochrome P450 family. (508 aa)
CYP11A1Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (521 aa)
FMO5Dimethylaniline monooxygenase [N-oxide-forming]. (533 aa)
ENSCATP00000036069Uncharacterized protein. (416 aa)
PAHPhenylalanine hydroxylase. (452 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa)
CYP2J2Cytochrome P450 family 2 subfamily J member 2; Belongs to the cytochrome P450 family. (502 aa)
CYP2B6Cytochrome P450 family 2 subfamily B member 6; Belongs to the cytochrome P450 family. (491 aa)
CYP2C18Cytochrome P450 family 2 subfamily C member 18; Belongs to the cytochrome P450 family. (490 aa)
TPH1Tryptophan hydroxylase 1. (444 aa)
AKR1D1Aldo-keto reductase family 1 member D1. (326 aa)
CYP2R1Cytochrome P450 family 2 subfamily R member 1; Belongs to the cytochrome P450 family. (533 aa)
LOC105598006Uncharacterized protein; Belongs to the cytochrome P450 family. (494 aa)
LOC105597447Aldo_ket_red domain-containing protein. (323 aa)
CYP26C1Cytochrome P450 family 26 subfamily C member 1; Belongs to the cytochrome P450 family. (522 aa)
CYP2S1Cytochrome P450 family 2 subfamily S member 1; Belongs to the cytochrome P450 family. (504 aa)
NOS1Nitric oxide synthase 1. (1461 aa)
MOXD1Monooxygenase DBH like 1. (613 aa)
LOC105597998Uncharacterized protein; Belongs to the cytochrome P450 family. (494 aa)
LOC105601617Uncharacterized protein; Belongs to the cytochrome P450 family. (524 aa)
CYP4X1Cytochrome P450 family 4 subfamily X member 1; Belongs to the cytochrome P450 family. (509 aa)
KMOKynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract. (470 aa)
LOC105571706Uncharacterized protein. (455 aa)
HMOX2Heme oxygenase 2. (377 aa)
CYP7B1Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family. (505 aa)
TPH2Tryptophan hydroxylase 2. (490 aa)
LOC105601619Uncharacterized protein; Belongs to the cytochrome P450 family. (524 aa)
LOC105573227Uncharacterized protein; Belongs to the cytochrome P450 family. (508 aa)
LOC105584398Uncharacterized protein. (503 aa)
CYP1A1Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. (512 aa)
CYP8B1Cytochrome P450 family 8 subfamily B member 1; Belongs to the cytochrome P450 family. (495 aa)
CYP7A1Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (504 aa)
LOC105586938Uncharacterized protein; Belongs to the cytochrome P450 family. (490 aa)
CYP4B1Cytochrome P450 family 4 subfamily B member 1; Belongs to the cytochrome P450 family. (511 aa)
KLKB1Kallikrein B1; Belongs to the peptidase S1 family. (638 aa)
CYP2U1Cytochrome P450 family 2 subfamily U member 1. (517 aa)
CYP2F1Cytochrome P450 family 2 subfamily F member 1; Belongs to the cytochrome P450 family. (491 aa)
LOC105581754Uncharacterized protein; Belongs to the cytochrome P450 family. (489 aa)
NOS2Nitric oxide synthase; Produces nitric oxide (NO). (1152 aa)
CYP1A2Cytochrome P450 family 1 subfamily A member 2; Belongs to the cytochrome P450 family. (516 aa)
CYP39A1Cytochrome P450 family 39 subfamily A member 1; Belongs to the cytochrome P450 family. (506 aa)
CYP26B1Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (512 aa)
CYP20A1Cytochrome P450 family 20 subfamily A member 1. (462 aa)
FMO2Dimethylaniline monooxygenase [N-oxide-forming]. (535 aa)
PCBD1Pterin-4 alpha-carbinolamine dehydratase 1. (104 aa)
AGMOAlkylglycerol monooxygenase; Belongs to the sterol desaturase family. (456 aa)
THTyrosine hydroxylase. (549 aa)
JMJD7Jumonji domain containing 7. (316 aa)
SQLESqualene epoxidase. (574 aa)
LOC105581138Uncharacterized protein. (457 aa)
LOC105601616Uncharacterized protein; Belongs to the cytochrome P450 family. (530 aa)
CYP4Z1Cytochrome P450 family 4 subfamily Z member 1. (334 aa)
CYP3A43Cytochrome P450 family 3 subfamily A member 43. (503 aa)
ENSCATP00000018702Uncharacterized protein. (425 aa)
LOC105576140Uncharacterized protein; Belongs to the cytochrome P450 family. (490 aa)
MICAL1Microtubule associated monooxygenase, calponin and LIM domain containing 1. (1080 aa)
CYP11B1Cytochrome P450 family 11 subfamily B member 1; Belongs to the cytochrome P450 family. (573 aa)
FMO3Flavin-containing monooxygenase. (419 aa)
ENSCATP00000000248BMERB domain-containing protein. (688 aa)
FMO3-2Flavin-containing monooxygenase. (414 aa)
NLRP11NLR family pyrin domain containing 11. (1034 aa)
TYRTyrosinase. (530 aa)
LOC105598973Uncharacterized protein; Belongs to the cytochrome P450 family. (518 aa)
LOC105572143Uncharacterized protein; Belongs to the cytochrome P450 family. (501 aa)
LOC105598002Uncharacterized protein; Belongs to the cytochrome P450 family. (494 aa)
TBXAS1Thromboxane A synthase 1; Belongs to the cytochrome P450 family. (580 aa)
LOC105587688Aldo_ket_red domain-containing protein. (323 aa)
CYP46A1Cytochrome P450 family 46 subfamily A member 1; Belongs to the cytochrome P450 family. (500 aa)
LOC105587685Aldo-keto reductase family 1 member C1. (275 aa)
PTGISProstacyclin synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2); Belongs to the cytochrome P450 family. (500 aa)
PAMPeptidylglycine alpha-amidating monooxygenase. (975 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (547 aa)
DBHDopamine beta-hydroxylase. (620 aa)
LOC105581294Uncharacterized protein; Belongs to the cytochrome P450 family. (443 aa)
COQ6Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (468 aa)
LOC105584179Uncharacterized protein; Belongs to the cytochrome P450 family. (514 aa)
CYP4F11Cytochrome P450 family 4 subfamily F member 11; Belongs to the cytochrome P450 family. (524 aa)
CYP27A1Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family. (531 aa)
LOC105576141Uncharacterized protein. (393 aa)
CYP51A1Cytochrome P450 family 51 subfamily A member 1; Belongs to the cytochrome P450 family. (509 aa)
CYP19A1Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family. (503 aa)
SAAL1Serum amyloid A like 1. (473 aa)
MIOXMyo-inositol oxygenase. (282 aa)
AKR1C3Aldo-keto reductase family 1 member C3. (274 aa)
PCBD2Pterin-4 alpha-carbinolamine dehydratase 2. (130 aa)
CYP27C1Cytochrome P450 family 27 subfamily C member 1; Belongs to the cytochrome P450 family. (372 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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