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| | MCM9 | Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1142 aa) |
| | FANCM | FA complementation group M. (2050 aa) |
| | PRIM1 | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (420 aa) |
| | ENSCATP00000014533 | Protein kinase domain-containing protein. (155 aa) |
| | LRWD1 | Leucine rich repeats and WD repeat domain containing 1. (647 aa) |
| | ENSCATP00000013584 | DNA_pol_B domain-containing protein. (383 aa) |
| | CDC6 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (599 aa) |
| | PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) |
| | RECQL4 | RecQ like helicase 4. (1208 aa) |
| | RFWD3 | Ring finger and WD repeat domain 3. (774 aa) |
| | EXD2 | Exonuclease 3'-5' domain containing 2. (620 aa) |
| | SETMAR | SET domain and mariner transposase fusion gene. (684 aa) |
| | RFC2 | Replication factor C subunit 2. (352 aa) |
| | ZGRF1 | Zinc finger GRF-type containing 1. (2075 aa) |
| | RFC4 | Replication factor C subunit 4. (349 aa) |
| | POLD1 | DNA polymerase. (1107 aa) |
| | RECQL5 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (991 aa) |
| | DDX11 | DEAD/H-box helicase 11. (918 aa) |
| | MCM2 | DNA helicase; Belongs to the MCM family. (904 aa) |
| | ENSCATP00000010534 | Sld5 domain-containing protein. (165 aa) |
| | MCM6 | DNA helicase; Belongs to the MCM family. (821 aa) |
| | TRAIP | TRAF interacting protein. (469 aa) |
| | POLG2 | DNA polymerase gamma 2, accessory subunit. (485 aa) |
| | THOC1 | THO complex 1. (651 aa) |
| | RRM2B | Ribonucleotide reductase regulatory TP53 inducible subunit M2B. (352 aa) |
| | POLB | DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (350 aa) |
| | SAMHD1 | SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1. (637 aa) |
| | ENSCATP00000005896 | TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (292 aa) |
| | ORC2 | Origin recognition complex subunit 2. (577 aa) |
| | POLA2 | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (598 aa) |
| | RFC1 | Replication factor C subunit 1. (1113 aa) |
| | POLQ | DNA polymerase theta. (2703 aa) |
| | RFC5 | Replication factor C subunit 5. (343 aa) |
| | RFC3 | Replication factor C subunit 3. (356 aa) |
| | POLE | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2286 aa) |
| | BAZ1A | Bromodomain adjacent to zinc finger domain 1A. (1556 aa) |
| | PNKP | Polynucleotide kinase 3'-phosphatase. (521 aa) |
| | RBBP8 | RB binding protein 8, endonuclease. (905 aa) |
| | ZNF830 | Zinc finger protein 830. (388 aa) |
| | GEN1 | GEN1 Holliday junction 5' flap endonuclease. (910 aa) |
| | MCM3 | DNA helicase; Belongs to the MCM family. (853 aa) |
| | MGME1 | Mitochondrial genome maintenance exonuclease 1; Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity but is also capable of endoduclease activity on linear substrates. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair, possibly via the processing of displaced DNA containing Okazaki fragments during RNA- primed DNA synthesis on the lagging strand or via processing of DNA flaps during long-patch base excision repair; Belongs to the MGME1 family. (342 aa) |
| | BRCA2 | BRCA2 DNA repair associated. (3419 aa) |
| | TWNK | Twinkle mtDNA helicase. (684 aa) |
| | CDC34 | Cell division cycle 34; Belongs to the ubiquitin-conjugating enzyme family. (236 aa) |
| | ORC5 | Origin recognition complex subunit 5. (435 aa) |
| | LOC105580479 | Uncharacterized protein; Belongs to the DEAD box helicase family. (764 aa) |
| | DDX50 | DExD-box helicase 50. (728 aa) |
| | CDC45 | Cell division cycle 45. (598 aa) |
| | MCM10 | Minichromosome maintenance 10 replication initiation factor. (877 aa) |
| | POLE2 | DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa) |
| | ALYREF | Aly/REF export factor. (290 aa) |
| | KHDC3L | KH domain containing 3 like, subcortical maternal complex member. (217 aa) |
| | POLE4 | DNA polymerase epsilon 4, accessory subunit. (117 aa) |
| | RAD51 | RAD51 recombinase; Belongs to the RecA family. (309 aa) |
| | DNA2 | DNA replication helicase/nuclease 2. (1056 aa) |
| | ENSCATP00000020493 | Uncharacterized protein. (150 aa) |
| | RPAIN | RPA interacting protein. (226 aa) |
| | ATR | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2573 aa) |
| | EME2 | Essential meiotic structure-specific endonuclease subunit 2. (379 aa) |
| | CDK2AP1 | Cyclin dependent kinase 2 associated protein 1. (132 aa) |
| | ENSCATP00000023183 | Helicase C-terminal domain-containing protein. (612 aa) |
| | RRM1 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (792 aa) |
| | WDHD1 | WD repeat and HMG-box DNA binding protein 1. (1126 aa) |
| | MCMBP | Minichromosome maintenance complex binding protein. (642 aa) |
| | FBH1 | F-box DNA helicase 1. (998 aa) |
| | GMNN | Geminin DNA replication inhibitor. (211 aa) |
| | GINS1 | GINS complex subunit 1. (196 aa) |
| | NOC3L | Nucleolar complex protein 3 homolog. (799 aa) |
| | TIMELESS | Timeless circadian regulator. (1208 aa) |
| | POLG | DNA polymerase gamma, catalytic subunit. (1228 aa) |
| | GMNC | Geminin coiled-coil domain containing. (334 aa) |
| | NRM | Nurim. (262 aa) |
| | ETAA1 | ETAA1 activator of ATR kinase. (898 aa) |
| | TONSL | Tonsoku like, DNA repair protein. (1390 aa) |
| | ENSCATP00000026110 | Uncharacterized protein. (222 aa) |
| | CENPS-CORT | CENPS-CORT readthrough. (143 aa) |
| | CCNE1 | Cyclin E1; Belongs to the cyclin family. (410 aa) |
| | CENPX | Centromere protein X. (133 aa) |
| | DNAJA3 | DnaJ heat shock protein family (Hsp40) member A3. (480 aa) |
| | WDR18 | WD repeat domain 18. (428 aa) |
| | DONSON | Downstream neighbor of SON. (564 aa) |
| | POLN | DNA polymerase nu. (869 aa) |
| | MUS81 | MUS81 structure-specific endonuclease subunit. (559 aa) |
| | FAM111A | Family with sequence similarity 111 member A. (611 aa) |
| | PRIMPOL | Primase and DNA directed polymerase. (427 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa) |
| | ENSCATP00000032441 | Uncharacterized protein. (630 aa) |
| | RTF2 | Replication termination factor 2. (329 aa) |
| | POLA1 | DNA polymerase. (1469 aa) |
| | MCM4 | DNA helicase; Belongs to the MCM family. (863 aa) |
| | DDX23 | DEAD-box helicase 23. (820 aa) |
| | SRPK2 | SRSF protein kinase 2. (698 aa) |
| | ENSCATP00000034029 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (581 aa) |
| | OOEP | Oocyte expressed protein. (149 aa) |
| | UPF1 | UPF1 RNA helicase and ATPase. (1073 aa) |
| | TIPIN | TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (307 aa) |
| | BOD1L1 | Biorientation of chromosomes in cell division 1 like 1. (2979 aa) |
| | WRN | WRN RecQ like helicase. (1418 aa) |
| | BLM | BLM RecQ like helicase. (1416 aa) |
| | POLD2 | DNA polymerase delta 2, accessory subunit. (504 aa) |
| | SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (944 aa) |
| | MMS22L | MMS22 like, DNA repair protein. (1243 aa) |
| | MRE11 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (708 aa) |
| | ENSCATP00000036401 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (262 aa) |
| | GINS3 | GINS complex subunit 3. (255 aa) |
| | CDK9 | Cyclin dependent kinase 9; Belongs to the protein kinase superfamily. (372 aa) |
| | SIRT7 | Sirtuin 7. (400 aa) |
| | ZRANB3 | Zinc finger RANBP2-type containing 3. (1049 aa) |
| | WRNIP1 | WRN helicase interacting protein 1. (665 aa) |
| | HMGA1 | Uncharacterized protein. (201 aa) |
| | ORC6 | Origin recognition complex subunit 6. (229 aa) |
| | GINS4 | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (223 aa) |
| | LIG1 | DNA ligase. (918 aa) |
| | ORC1 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (858 aa) |
| | BARD1 | BRCA1 associated RING domain 1. (777 aa) |
| | HELB | DNA helicase B. (1087 aa) |
| | ORC3 | Origin recognition complex subunit 3. (716 aa) |
| | ZPR1 | ZPR1 zinc finger. (459 aa) |
| | POLD3 | Uncharacterized protein. (466 aa) |
| | POLE3 | DNA polymerase epsilon 3, accessory subunit. (147 aa) |
| | DDX21 | DExD-box helicase 21. (783 aa) |
| | GINS2 | DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (185 aa) |
| | MCM5 | DNA helicase; Belongs to the MCM family. (734 aa) |
| | CDT1 | Chromatin licensing and DNA replication factor 1. (545 aa) |
| | NUCKS1 | Nuclear casein kinase and cyclin dependent kinase substrate 1. (243 aa) |
| | LIG3 | DNA ligase. (1009 aa) |
| | ATAD5 | ATPase family AAA domain containing 5. (1832 aa) |
| | ENSCATP00000045189 | Uncharacterized protein. (684 aa) |
| | ORC4 | Origin recognition complex subunit 4. (339 aa) |
| | CCNE2 | Cyclin E2; Belongs to the cyclin family. (404 aa) |
| | TOPBP1 | DNA topoisomerase II binding protein 1. (1527 aa) |
