STRINGSTRING
ENSCATP00000012999 ENSCATP00000012999 MED28 MED28 TAF3 TAF3 ENSCATP00000012244 ENSCATP00000012244 ENSCATP00000012198 ENSCATP00000012198 E2F3 E2F3 TAF1 TAF1 GTF2F2 GTF2F2 ENSCATP00000033319 ENSCATP00000033319 MED30 MED30 TBP TBP MED11 MED11 ENSCATP00000030828 ENSCATP00000030828 TAF5 TAF5 E2F2 E2F2 MED7 MED7 ENSCATP00000007311 ENSCATP00000007311 LOC105594328 LOC105594328 TAF7L TAF7L MED8 MED8 POLR2D POLR2D TAF2 TAF2 MED9 MED9 MED24 MED24 TAF11 TAF11 MED19 MED19 CDK7 CDK7 ELOC ELOC POLR2G POLR2G MED31 MED31 GTF2F1 GTF2F1 LOC105584562 LOC105584562 ELOA ELOA POLR2I POLR2I MED14 MED14 GTF2E1 GTF2E1 MED23 MED23 ENSCATP00000030465 ENSCATP00000030465 MED25 MED25 TAF10 TAF10 TAF6 TAF6 MED29 MED29 ENSCATP00000001579 ENSCATP00000001579 TAF4 TAF4 STON1 STON1 MED27 MED27 GTF2B GTF2B GTF2H5 GTF2H5 GTF2A1 GTF2A1 TAF12 TAF12 MED22 MED22 ENSCATP00000041238 ENSCATP00000041238 MED15 MED15 TAF8 TAF8 ENSCATP00000038535 ENSCATP00000038535 LOC105576107 LOC105576107 MED26 MED26 CCNH CCNH CDK9 CDK9 MED4 MED4 MED21 MED21 GTF2A2 GTF2A2 LOC105594398 LOC105594398 GTF2E2 GTF2E2 LOC105576377 LOC105576377 MED18 MED18 TAF4B TAF4B MAZ MAZ DR1 DR1 ELOB ELOB PPARGC1A PPARGC1A ERCC3 ERCC3 LOC105592524 LOC105592524 ENSCATP00000016162 ENSCATP00000016162 TAF6L TAF6L MED16 MED16
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSCATP00000012999Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (115 aa)
MED28Mediator complex subunit 28. (178 aa)
TAF3TATA-box binding protein associated factor 3. (931 aa)
ENSCATP00000012244Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (417 aa)
ENSCATP00000012198TAFII28 domain-containing protein. (196 aa)
E2F3E2F transcription factor 3. (467 aa)
TAF1Transcription initiation factor TFIID subunit. (1927 aa)
GTF2F2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa)
ENSCATP00000033319Uncharacterized protein. (66 aa)
MED30Mediator complex subunit 30. (178 aa)
TBPTATA-box binding protein. (327 aa)
MED11Mediator of RNA polymerase II transcription subunit 11; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (117 aa)
ENSCATP00000030828TFIIA_gamma_C domain-containing protein. (74 aa)
TAF5TATA-box binding protein associated factor 5. (800 aa)
E2F2E2F transcription factor 2. (437 aa)
MED7Mediator of RNA polymerase II transcription subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. (232 aa)
ENSCATP00000007311Uncharacterized protein. (297 aa)
LOC105594328Uncharacterized protein. (86 aa)
TAF7LTATA-box binding protein associated factor 7 like. (464 aa)
MED8Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (337 aa)
POLR2DRNA polymerase II subunit D. (142 aa)
TAF2TATA-box binding protein associated factor 2. (1199 aa)
MED9Mediator of RNA polymerase II transcription subunit 9; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (146 aa)
MED24Mediator complex subunit 24. (1008 aa)
TAF11TATA-box binding protein associated factor 11. (211 aa)
MED19Mediator of RNA polymerase II transcription subunit 19; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (261 aa)
CDK7Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa)
ELOCElongin C. (112 aa)
POLR2GRNA polymerase II subunit G. (244 aa)
MED31Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (131 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (517 aa)
LOC105584562Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (112 aa)
ELOAElongin A. (800 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
MED14Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1454 aa)
GTF2E1General transcription factor IIE subunit 1. (439 aa)
MED23Mediator complex subunit 23. (1374 aa)
ENSCATP00000030465Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (199 aa)
MED25Mediator complex subunit 25. (733 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa)
TAF6TATA-box binding protein associated factor 6. (738 aa)
MED29Mediator complex subunit 29. (221 aa)
ENSCATP00000001579Uncharacterized protein. (97 aa)
TAF4TATA-box binding protein associated factor 4. (994 aa)
STON1Stonin-1; May be involved in the endocytic machinery. (1182 aa)
MED27Mediator complex subunit 27. (311 aa)
GTF2BGeneral transcription factor IIB. (373 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
GTF2A1General transcription factor IIA subunit 1. (376 aa)
TAF12TATA-box binding protein associated factor 12. (213 aa)
MED22Mediator complex subunit 22. (200 aa)
ENSCATP00000041238TFIIA_gamma_N domain-containing protein. (91 aa)
MED15Mediator of RNA polymerase II transcription subunit 15; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (789 aa)
TAF8TATA-box binding protein associated factor 8. (338 aa)
ENSCATP00000038535E2F_CC-MB domain-containing protein. (193 aa)
LOC105576107Protein kinase domain-containing protein. (322 aa)
MED26TFIIS N-terminal domain-containing protein. (600 aa)
CCNHCyclin H; Belongs to the cyclin family. (325 aa)
CDK9Cyclin dependent kinase 9; Belongs to the protein kinase superfamily. (372 aa)
MED4Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (300 aa)
MED21Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (152 aa)
GTF2A2Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (109 aa)
LOC105594398TATA-box binding protein associated factor 13. (92 aa)
GTF2E2Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (291 aa)
LOC105576377Uncharacterized protein. (261 aa)
MED18Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (208 aa)
TAF4BTATA-box binding protein associated factor 4b. (862 aa)
MAZMYC associated zinc finger protein. (493 aa)
DR1Down-regulator of transcription 1. (176 aa)
ELOBElongin B. (167 aa)
PPARGC1APPARG coactivator 1 alpha. (798 aa)
ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit. (782 aa)
LOC105592524TFIIS N-terminal domain-containing protein. (543 aa)
ENSCATP00000016162TAFII28 domain-containing protein. (167 aa)
TAF6LTATA-box binding protein associated factor 6 like. (622 aa)
MED16Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (959 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
Server load: low (16%) [HD]