STRINGSTRING
ENSCATP00000004066 ENSCATP00000004066 DCUN1D3 DCUN1D3 BRCA2 BRCA2 C9orf116 C9orf116 MAP3K4 MAP3K4 IMPACT IMPACT BAK1 BAK1 TP53 TP53 WRN WRN POLH POLH BCL3 BCL3 HMGN1 HMGN1 ENSCATP00000008552 ENSCATP00000008552
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSCATP00000004066Uncharacterized protein. (189 aa)
DCUN1D3DCN1-like protein. (304 aa)
BRCA2BRCA2 DNA repair associated. (3419 aa)
C9orf116Chromosome 9 open reading frame 116. (136 aa)
MAP3K4Mitogen-activated protein kinase kinase kinase 4. (1771 aa)
IMPACTImpact RWD domain protein. (320 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (402 aa)
WRNWRN RecQ like helicase. (1418 aa)
POLHDNA polymerase eta. (712 aa)
BCL3BCL3 transcription coactivator. (454 aa)
HMGN1Uncharacterized protein. (116 aa)
ENSCATP00000008552DCN1-like protein. (293 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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