STRINGSTRING
SMAD4 SMAD4 LTK LTK BNIP3 BNIP3 GATA6 GATA6 MAP3K5 MAP3K5 TIGAR TIGAR POU4F2 POU4F2 CAMK2D CAMK2D TP53 TP53 FNDC1 FNDC1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SMAD4Mothers against decapentaplegic homolog. (552 aa)
LTKTyrosine-protein kinase receptor. (864 aa)
BNIP3BCL2 interacting protein 3. (194 aa)
GATA6GATA binding protein 6. (595 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1374 aa)
TIGARTP53 induced glycolysis regulatory phosphatase. (270 aa)
POU4F2POU domain protein. (408 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (533 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (402 aa)
FNDC1Fibronectin type III domain containing 1. (1854 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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