38 items (Cercocebus atys) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	P2RY6	Pyrimidinergic receptor P2Y6. (328 aa)
	LPAR1	Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (364 aa)
	GNAQ	Uncharacterized protein. (359 aa)
	KIT	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa)
	HTR2B	5-hydroxytryptamine receptor 2B. (481 aa)
	ENSCATP00000006523	Prohibitin. (286 aa)
	SELE	Selectin E. (610 aa)
	ENSCATP00000009925	Prohibitin. (197 aa)
	ESR1	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
	ENSCATP00000013280	Prohibitin. (191 aa)
	HRAS	HRas proto-oncogene, GTPase. (189 aa)
	ITK	Tyrosine-protein kinase. (620 aa)
	ENSCATP00000016044	Protein kinase domain-containing protein. (357 aa)
	ENSCATP00000016893	Prohibitin. (146 aa)
	ENSCATP00000017128	Prohibitin. (87 aa)
	LOC105580425	Prohibitin. (264 aa)
	ENSCATP00000017574	Uncharacterized protein. (96 aa)
	ADCYAP1R1	ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. (523 aa)
	CD86	CD86 molecule. (329 aa)
	FLT1	Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1338 aa)
	ABL2	Tyrosine-protein kinase. (1172 aa)
	RASGRP4	RAS guanyl releasing protein 4. (673 aa)
	LOC105573207	Prohibitin. (238 aa)
	NMUR1	Neuromedin U receptor 1; Belongs to the G-protein coupled receptor 1 family. (426 aa)
	HTR2A	5-hydroxytryptamine receptor 2A. (471 aa)
	PLCB2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1161 aa)
	LOC105583051	Prohibitin. (299 aa)
	ENSCATP00000034176	Prohibitin. (252 aa)
	TXK	Tyrosine-protein kinase. (527 aa)
	EDNRA	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
	ARHGAP6	Rho GTPase activating protein 6. (977 aa)
	AVPR1A	Vasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (421 aa)
	AVPR1B	Vasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (424 aa)
	FGFR1	Fibroblast growth factor receptor. (820 aa)
	PHB	Prohibitin. (272 aa)
	PDGFRB	Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
	GNA15	G protein subunit alpha 15. (374 aa)
	ADRA1A	Adrenoceptor alpha 1A. (463 aa)

Your Current Organism:

Cercocebus atys

NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCYAP1R1	GNAQ	ENSCATP00000019606	ENSCATP00000000601	ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family.	Uncharacterized protein.	0.911
ADRA1A	GNA15	ENSCATP00000045473	ENSCATP00000044999	Adrenoceptor alpha 1A.	G protein subunit alpha 15.	0.787
ADRA1A	GNAQ	ENSCATP00000045473	ENSCATP00000000601	Adrenoceptor alpha 1A.	Uncharacterized protein.	0.940
ADRA1A	PLCB2	ENSCATP00000045473	ENSCATP00000027782	Adrenoceptor alpha 1A.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.456
AVPR1A	AVPR1B	ENSCATP00000040607	ENSCATP00000041101	Vasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.	Vasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.	0.904
AVPR1A	ESR1	ENSCATP00000040607	ENSCATP00000012127	Vasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.412
AVPR1A	GNA15	ENSCATP00000040607	ENSCATP00000044999	Vasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.	G protein subunit alpha 15.	0.781
AVPR1A	GNAQ	ENSCATP00000040607	ENSCATP00000000601	Vasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.	Uncharacterized protein.	0.907
AVPR1A	PLCB2	ENSCATP00000040607	ENSCATP00000027782	Vasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.433
AVPR1B	AVPR1A	ENSCATP00000041101	ENSCATP00000040607	Vasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.	Vasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.	0.904
AVPR1B	GNA15	ENSCATP00000041101	ENSCATP00000044999	Vasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.	G protein subunit alpha 15.	0.781
AVPR1B	GNAQ	ENSCATP00000041101	ENSCATP00000000601	Vasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.	Uncharacterized protein.	0.900
AVPR1B	PLCB2	ENSCATP00000041101	ENSCATP00000027782	Vasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.433
EDNRA	GNA15	ENSCATP00000038523	ENSCATP00000044999	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	G protein subunit alpha 15.	0.781
EDNRA	GNAQ	ENSCATP00000038523	ENSCATP00000000601	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	Uncharacterized protein.	0.926
EDNRA	PLCB2	ENSCATP00000038523	ENSCATP00000027782	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.449
ENSCATP00000006523	ENSCATP00000009925	ENSCATP00000006523	ENSCATP00000009925	Prohibitin.	Prohibitin.	0.892
ENSCATP00000006523	ENSCATP00000013280	ENSCATP00000006523	ENSCATP00000013280	Prohibitin.	Prohibitin.	0.891
ENSCATP00000006523	ENSCATP00000016893	ENSCATP00000006523	ENSCATP00000016893	Prohibitin.	Prohibitin.	0.880
ENSCATP00000006523	ENSCATP00000034176	ENSCATP00000006523	ENSCATP00000034176	Prohibitin.	Prohibitin.	0.892