(82 nodes) Myosin phosphatase activity network (Cercocebus atys)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SSH1	Slingshot protein phosphatase 1. (1122 aa)
	PDXP	Pyridoxal phosphatase; Belongs to the HAD-like hydrolase superfamily. (300 aa)
	SSU72	SSU72 homolog, RNA polymerase II CTD phosphatase. (194 aa)
	PGAM5	PGAM family member 5, mitochondrial serine/threonine protein phosphatase. (289 aa)
	TMEM240	Transmembrane protein 240. (173 aa)
	ENSCATP00000026358	Coilin_N domain-containing protein. (484 aa)
	CDC14B	Cell division cycle 14B. (498 aa)
	PPP1CB	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
	PPM1E	Protein phosphatase, Mg2+/Mn2+ dependent 1E. (761 aa)
	ENSCATP00000029353	Uncharacterized protein. (77 aa)
	DUSP10	Dual specificity phosphatase 10. (505 aa)
	PPEF2	Serine/threonine-protein phosphatase with EF-hands. (753 aa)
	PPM1A	Protein phosphatase, Mg2+/Mn2+ dependent 1A. (455 aa)
	DUSP23	Dual specificity phosphatase 23. (150 aa)
	PPM1N	Protein phosphatase, Mg2+/Mn2+ dependent 1N (putative). (430 aa)
	DUSP5	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (384 aa)
	PPM1G	Protein phosphatase, Mg2+/Mn2+ dependent 1G. (547 aa)
	PPM1L	Protein phosphatase, Mg2+/Mn2+ dependent 1L. (360 aa)
	SSH3	Slingshot protein phosphatase 3. (657 aa)
	PPP3CC	Serine/threonine-protein phosphatase. (438 aa)
	PPP2CA	Serine/threonine-protein phosphatase. (309 aa)
	MYH3	Myosin heavy chain 3; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1940 aa)
	PPP1CC	Serine/threonine-protein phosphatase. (293 aa)
	DUSP3	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (185 aa)
	PHLPP2	PH domain and leucine rich repeat protein phosphatase 2. (1363 aa)
	DUSP15	Dual specificity phosphatase 15; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (255 aa)
	PPM1D	Protein phosphatase, Mg2+/Mn2+ dependent 1D. (605 aa)
	PPM1K	Protein phosphatase, Mg2+/Mn2+ dependent 1K. (372 aa)
	DUPD1	Dual specificity phosphatase and pro isomerase domain containing 1; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (247 aa)
	DUSP13	Dual specificity phosphatase 13; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (333 aa)
	CPPED1	Calcineurin like phosphoesterase domain containing 1. (314 aa)
	DUSP6	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa)
	IQUB	IQ motif and ubiquitin domain containing. (790 aa)
	ILKAP	ILK associated serine/threonine phosphatase. (392 aa)
	DUSP2	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (315 aa)
	PPEF1	Serine/threonine-protein phosphatase with EF-hands. (653 aa)
	CTDNEP1	CTD nuclear envelope phosphatase 1. (244 aa)
	DUSP14	Dual specificity phosphatase 14; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (195 aa)
	CTDSPL	CTD small phosphatase like. (302 aa)
	ENSCATP00000044345	FCP1 homology domain-containing protein. (206 aa)
	DUSP26	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (211 aa)
	DUSP8	Dual specificity phosphatase 8. (632 aa)
	PPP4C	Serine/threonine-protein phosphatase. (307 aa)
	CDKN3	Cyclin-dependent kinase inhibitor 3; May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues. (212 aa)
	DUSP28	Dual specificity phosphatase 28. (176 aa)
	PPM1M	Protein phosphatase, Mg2+/Mn2+ dependent 1M. (474 aa)
	DUSP9	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (384 aa)
	PPP2CB	Serine/threonine-protein phosphatase. (309 aa)
	PPP3CA	Serine/threonine-protein phosphatase. (521 aa)
	PPM1J	Protein phosphatase, Mg2+/Mn2+ dependent 1J. (505 aa)
	PPTC7	Protein phosphatase; Belongs to the PP2C family. (304 aa)
	EPM2A	EPM2A glucan phosphatase, laforin. (331 aa)
	ENSCATP00000008457	Coilin_N domain-containing protein. (468 aa)
	DUSP1	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (367 aa)
	CTDSP2	CTD small phosphatase 2. (271 aa)
	EYA1	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (621 aa)
	MYH8	Myosin heavy chain 8; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1937 aa)
	DUSP16	Dual specificity phosphatase 16. (665 aa)
	DUSP22	Dual specificity phosphatase 22; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (184 aa)
	PTEN	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
	PPP1CA	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
	PPP6C	Serine/threonine-protein phosphatase. (338 aa)
	PHLPP1	PH domain and leucine rich repeat protein phosphatase 1. (1716 aa)
	PPP5C	Serine/threonine-protein phosphatase. (501 aa)
	DUSP4	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (382 aa)
	CDC14A	Cell division cycle 14A. (595 aa)
	SSH2	Slingshot protein phosphatase 2. (1450 aa)
	CDC14C	Cell division cycle 14C. (586 aa)
	PPP3CB	Serine/threonine-protein phosphatase. (525 aa)
	UBLCP1	Ubiquitin like domain containing CTD phosphatase 1. (318 aa)
	CTDP1	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (964 aa)
	PPM1B	Protein phosphatase, Mg2+/Mn2+ dependent 1B. (479 aa)
	PPM1H	Protein phosphatase, Mg2+/Mn2+ dependent 1H. (514 aa)
	RPAP2	RNA polymerase II associated protein 2. (653 aa)
	PTPMT1	Protein tyrosine phosphatase mitochondrial 1. (201 aa)
	DUSP12	Dual specificity phosphatase 12. (340 aa)
	PPM1F	Protein phosphatase, Mg2+/Mn2+ dependent 1F. (386 aa)
	ENSCATP00000020542	Uncharacterized protein. (217 aa)
	DUSP19	Dual specificity phosphatase 19; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (217 aa)
	ENSCATP00000021984	PPM-type phosphatase domain-containing protein. (358 aa)
	CTDSP1	CTD small phosphatase 1. (261 aa)
	DUSP7	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (419 aa)

Your Current Organism:

Cercocebus atys

NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC14A	CDC14B	ENSCATP00000015846	ENSCATP00000027851	Cell division cycle 14A.	Cell division cycle 14B.	0.895
CDC14A	CDC14C	ENSCATP00000015846	ENSCATP00000016645	Cell division cycle 14A.	Cell division cycle 14C.	0.896
CDC14B	CDC14A	ENSCATP00000027851	ENSCATP00000015846	Cell division cycle 14B.	Cell division cycle 14A.	0.895
CDC14B	CDC14C	ENSCATP00000027851	ENSCATP00000016645	Cell division cycle 14B.	Cell division cycle 14C.	0.894
CDC14C	CDC14A	ENSCATP00000016645	ENSCATP00000015846	Cell division cycle 14C.	Cell division cycle 14A.	0.896
CDC14C	CDC14B	ENSCATP00000016645	ENSCATP00000027851	Cell division cycle 14C.	Cell division cycle 14B.	0.894
CTDP1	CTDSP1	ENSCATP00000017103	ENSCATP00000022752	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	CTD small phosphatase 1.	0.424
CTDP1	RPAP2	ENSCATP00000017103	ENSCATP00000018142	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	RNA polymerase II associated protein 2.	0.555
CTDP1	SSU72	ENSCATP00000017103	ENSCATP00000025236	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	SSU72 homolog, RNA polymerase II CTD phosphatase.	0.508
CTDP1	TMEM240	ENSCATP00000017103	ENSCATP00000026234	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	Transmembrane protein 240.	0.508
CTDP1	UBLCP1	ENSCATP00000017103	ENSCATP00000017022	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	Ubiquitin like domain containing CTD phosphatase 1.	0.563
CTDSP1	CTDP1	ENSCATP00000022752	ENSCATP00000017103	CTD small phosphatase 1.	RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.	0.424
CTDSP1	CTDSPL	ENSCATP00000022752	ENSCATP00000044348	CTD small phosphatase 1.	CTD small phosphatase like.	0.726
CTDSPL	CTDSP1	ENSCATP00000044348	ENSCATP00000022752	CTD small phosphatase like.	CTD small phosphatase 1.	0.726
DUSP10	DUSP16	ENSCATP00000030163	ENSCATP00000011889	Dual specificity phosphatase 10.	Dual specificity phosphatase 16.	0.673
DUSP10	DUSP8	ENSCATP00000030163	ENSCATP00000043370	Dual specificity phosphatase 10.	Dual specificity phosphatase 8.	0.474
DUSP16	DUSP10	ENSCATP00000011889	ENSCATP00000030163	Dual specificity phosphatase 16.	Dual specificity phosphatase 10.	0.673
DUSP16	DUSP6	ENSCATP00000011889	ENSCATP00000037371	Dual specificity phosphatase 16.	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.439
DUSP16	DUSP7	ENSCATP00000011889	ENSCATP00000023343	Dual specificity phosphatase 16.	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.482
DUSP6	DUSP16	ENSCATP00000037371	ENSCATP00000011889	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Dual specificity phosphatase 16.	0.439