STRINGSTRING
PTPN12 PTPN12 NCF1 NCF1 PTTG1 PTTG1 SH3BGRL2 SH3BGRL2 CBL CBL CBLB CBLB TP53BP2 TP53BP2 PLSCR1 PLSCR1 DTX1 DTX1 ABI1 ABI1 WAS WAS REPS1 REPS1 INPP5J INPP5J ABI3 ABI3 PLSCR3 PLSCR3 SKAP1 SKAP1 KHDRBS1 KHDRBS1 ADAM12 ADAM12 SIRPA SIRPA GRB2 GRB2 ARHGAP1 ARHGAP1 OSTF1 OSTF1 CD3E CD3E CTTNBP2 CTTNBP2 USP8 USP8 TOM1L1 TOM1L1 VASP VASP KHDRBS2 KHDRBS2 SYNJ2 SYNJ2 RAD9B RAD9B CNTNAP1 CNTNAP1 ITGB1BP2 ITGB1BP2 LOC105573172 LOC105573172 ENSCATP00000038701 ENSCATP00000038701 ARHGAP6 ARHGAP6 MAPK15 MAPK15 CRK CRK CBLC CBLC NOXA1 NOXA1 SIRPB1 SIRPB1 LRP2 LRP2 HCLS1 HCLS1 ADAM10 ADAM10 PTTG2 PTTG2 SH3BGR SH3BGR RUFY2 RUFY2 ENSCATP00000035156 ENSCATP00000035156 WIPF3 WIPF3 ELMO1 ELMO1 SIRPG SIRPG EPS15 EPS15 UVRAG UVRAG ESPN ESPN PTPN22 PTPN22 DPYSL3 DPYSL3 DNM2 DNM2 LANCL1 LANCL1 INPPL1 INPPL1 SGIP1 SGIP1 ABI2 ABI2 BCAR1 BCAR1 ADAM15 ADAM15 SHANK2 SHANK2 SOCS7 SOCS7 AFAP1 AFAP1 SYNGAP1 SYNGAP1 PLSCR4 PLSCR4 QKI QKI ADAM17 ADAM17 ENKUR ENKUR PAK3 PAK3 EVL EVL ARHGAP17 ARHGAP17 SHANK1 SHANK1 ERRFI1 ERRFI1 CRB3 CRB3 DOCK1 DOCK1 DRD4 DRD4 DNAJC6 DNAJC6 KHDRBS3 KHDRBS3 CYBA CYBA ELMO3 ELMO3 DENND1A DENND1A SH3KBP1 SH3KBP1 SYNJ1 SYNJ1 DOCK4 DOCK4 DAB2IP DAB2IP SH3BP5 SH3BP5 CCDC6 CCDC6 ADAM9 ADAM9 ZNF106 ZNF106 PRKN PRKN MICAL1 MICAL1 SIRPD SIRPD SH3BP2 SH3BP2 ABL1 ABL1 ADAM19 ADAM19 ARHGAP31 ARHGAP31 SH3BGRL SH3BGRL ARHGAP27 ARHGAP27 DOCK3 DOCK3 ENSCATP00000013592 ENSCATP00000013592 HIP1R HIP1R MYPN MYPN GRIK5 GRIK5 LYN LYN ENSCATP00000011902 ENSCATP00000011902 MVB12A MVB12A ENSCATP00000011388 ENSCATP00000011388 AFAP1L1 AFAP1L1 WASF2 WASF2 RAPGEF1 RAPGEF1 CD2AP CD2AP ELMO2 ELMO2 WIPF1 WIPF1 SH2D2A SH2D2A SHANK3 SHANK3 RAD9A RAD9A FMN1 FMN1 NCKIPSD NCKIPSD CASP9 CASP9 AFAP1L2 AFAP1L2 FUT8 FUT8 INPP5D INPP5D SOS1 SOS1 GPX1 GPX1 RUFY1 RUFY1 EFS EFS PTPN6 PTPN6 ENAH ENAH ENSCATP00000001512 ENSCATP00000001512
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PTPN12Tyrosine-protein phosphatase non-receptor type 12; Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades. (780 aa)
NCF1Neutrophil cytosolic factor 1. (423 aa)
PTTG1PTTG1 regulator of sister chromatid separation, securin. (202 aa)
SH3BGRL2SH3 domain-binding glutamic acid-rich-like protein; Belongs to the SH3BGR family. (107 aa)
CBLCbl proto-oncogene. (907 aa)
CBLBCbl proto-oncogene B. (1027 aa)
TP53BP2Tumor protein p53 binding protein 2. (1134 aa)
PLSCR1Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (313 aa)
DTX1Deltex E3 ubiquitin ligase 1. (622 aa)
ABI1Abl interactor 1. (508 aa)
WASWASP actin nucleation promoting factor. (503 aa)
REPS1RALBP1 associated Eps domain containing 1. (796 aa)
INPP5JInositol polyphosphate-5-phosphatase J. (1001 aa)
ABI3ABI family member 3. (366 aa)
PLSCR3Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (295 aa)
SKAP1Src kinase associated phosphoprotein 1. (359 aa)
KHDRBS1KH RNA binding domain containing, signal transduction associated 1. (443 aa)
ADAM12ADAM metallopeptidase domain 12. (909 aa)
SIRPAUncharacterized protein. (507 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
ARHGAP1Rho GTPase activating protein 1. (462 aa)
OSTF1Osteoclast stimulating factor 1. (214 aa)
CD3ECD3e molecule. (198 aa)
CTTNBP2Cortactin binding protein 2. (1637 aa)
USP8Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1118 aa)
TOM1L1Target of myb1 like 1 membrane trafficking protein; Belongs to the TOM1 family. (461 aa)
VASPVasodilator stimulated phosphoprotein. (431 aa)
KHDRBS2KH RNA binding domain containing, signal transduction associated 2. (349 aa)
SYNJ2Synaptojanin 2. (1496 aa)
RAD9BCell cycle checkpoint control protein; Belongs to the rad9 family. (417 aa)
CNTNAP1Contactin associated protein 1. (1366 aa)
ITGB1BP2Integrin subunit beta 1 binding protein 2. (348 aa)
LOC105573172Uncharacterized protein. (906 aa)
ENSCATP00000038701Uncharacterized protein. (788 aa)
ARHGAP6Rho GTPase activating protein 6. (977 aa)
MAPK15Mitogen-activated protein kinase. (544 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
CBLCCbl proto-oncogene C. (571 aa)
NOXA1NADPH oxidase activator 1. (483 aa)
SIRPB1Uncharacterized protein. (397 aa)
LRP2LDL receptor related protein 2. (4655 aa)
HCLS1Hematopoietic cell-specific Lyn substrate 1. (476 aa)
ADAM10ADAM metallopeptidase domain 10. (748 aa)
PTTG2Pituitary tumor-transforming 2. (174 aa)
SH3BGRSH3 domain binding glutamate rich protein. (240 aa)
RUFY2RUN and FYVE domain containing 2. (641 aa)
ENSCATP00000035156IGc1 domain-containing protein. (178 aa)
WIPF3WAS/WASL interacting protein family member 3. (486 aa)
ELMO1Engulfment and cell motility 1. (727 aa)
SIRPGSignal regulatory protein gamma. (394 aa)
EPS15Epidermal growth factor receptor pathway substrate 15. (887 aa)
UVRAGUV radiation resistance associated. (699 aa)
ESPNEspin. (1295 aa)
PTPN22Protein tyrosine phosphatase non-receptor type 22. (812 aa)
DPYSL3Dihydropyrimidinase like 3. (684 aa)
DNM2Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (870 aa)
LANCL1LanC like 1. (399 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (1258 aa)
SGIP1SH3 domain GRB2 like endophilin interacting protein 1. (859 aa)
ABI2Abl interactor 2. (513 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (916 aa)
ADAM15ADAM metallopeptidase domain 15. (861 aa)
SHANK2SH3 and multiple ankyrin repeat domains 2. (1849 aa)
SOCS7Suppressor of cytokine signaling 7. (644 aa)
AFAP1Actin filament associated protein 1. (814 aa)
SYNGAP1Synaptic Ras GTPase activating protein 1. (1303 aa)
PLSCR4Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (329 aa)
QKIQKI, KH domain containing RNA binding. (342 aa)
ADAM17ADAM metallopeptidase domain 17. (824 aa)
ENKUREnkurin, TRPC channel interacting protein. (256 aa)
PAK3P21 (RAC1) activated kinase 3. (580 aa)
EVLEnah/Vasp-like; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (418 aa)
ARHGAP17Rho GTPase activating protein 17. (881 aa)
SHANK1SH3 and multiple ankyrin repeat domains 1. (2170 aa)
ERRFI1ERBB receptor feedback inhibitor 1. (462 aa)
CRB3Crumbs cell polarity complex component 3. (125 aa)
DOCK1Dedicator of cytokinesis 1; Belongs to the DOCK family. (1886 aa)
DRD4Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family. (415 aa)
DNAJC6DnaJ heat shock protein family (Hsp40) member C6. (970 aa)
KHDRBS3KH RNA binding domain containing, signal transduction associated 3. (346 aa)
CYBACytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. (195 aa)
ELMO3Engulfment and cell motility 3. (763 aa)
DENND1ADENN domain containing 1A. (1009 aa)
SH3KBP1SH3 domain containing kinase binding protein 1. (665 aa)
SYNJ1Synaptojanin 1. (1614 aa)
DOCK4Dedicator of cytokinesis 4; Belongs to the DOCK family. (2003 aa)
DAB2IPDAB2 interacting protein. (1189 aa)
SH3BP5SH3 domain binding protein 5. (455 aa)
CCDC6Coiled-coil domain containing 6. (474 aa)
ADAM9ADAM metallopeptidase domain 9. (743 aa)
ZNF106Zinc finger protein 106. (1883 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa)
MICAL1Microtubule associated monooxygenase, calponin and LIM domain containing 1. (1080 aa)
SIRPDSignal regulatory protein delta. (198 aa)
SH3BP2SH3 domain binding protein 2. (605 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
ADAM19ADAM metallopeptidase domain 19. (918 aa)
ARHGAP31Rho GTPase activating protein 31. (1442 aa)
SH3BGRLSH3 domain-binding glutamic acid-rich-like protein; Belongs to the SH3BGR family. (114 aa)
ARHGAP27Rho GTPase activating protein 27. (887 aa)
DOCK3Dedicator of cytokinesis 3; Belongs to the DOCK family. (1302 aa)
ENSCATP00000013592Non-specific serine/threonine protein kinase. (480 aa)
HIP1RHuntingtin interacting protein 1 related. (1068 aa)
MYPNMyopalladin. (1320 aa)
GRIK5Glutamate ionotropic receptor kainate type subunit 5. (980 aa)
LYNTyrosine-protein kinase. (507 aa)
ENSCATP00000011902Uncharacterized protein. (314 aa)
MVB12AMultivesicular body subunit 12A. (273 aa)
ENSCATP00000011388Uncharacterized protein. (232 aa)
AFAP1L1Actin filament associated protein 1 like 1. (768 aa)
WASF2WASP family member 2. (498 aa)
RAPGEF1Rap guanine nucleotide exchange factor 1. (1303 aa)
CD2APCD2 associated protein. (639 aa)
ELMO2Engulfment and cell motility 2. (720 aa)
WIPF1WAS/WASL interacting protein family member 1. (510 aa)
SH2D2ASH2 domain containing 2A. (371 aa)
SHANK3SH3 and multiple ankyrin repeat domains 3. (1739 aa)
RAD9ACell cycle checkpoint control protein; Belongs to the rad9 family. (390 aa)
FMN1Formin 1. (1425 aa)
NCKIPSDNCK interacting protein with SH3 domain. (719 aa)
CASP9Caspase 9; Belongs to the peptidase C14A family. (416 aa)
AFAP1L2Actin filament associated protein 1 like 2. (864 aa)
FUT8Alpha-(1,6)-fucosyltransferase; Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans. Belongs to the glycosyltransferase 23 family. (575 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1184 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa)
GPX1Glutathione peroxidase; Belongs to the glutathione peroxidase family. (197 aa)
RUFY1RUN and FYVE domain containing 1. (600 aa)
EFSEmbryonal Fyn-associated substrate. (561 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (623 aa)
ENAHENAH actin regulator. (790 aa)
ENSCATP00000001512Uncharacterized protein. (182 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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