STRINGSTRING
CAMK1D CAMK1D MAPK1 MAPK1 SBK1 SBK1 RPS6KA4 RPS6KA4 CDC7 CDC7 ENSCATP00000016805 ENSCATP00000016805 RPS6KA1 RPS6KA1 STK32B STK32B ULK2 ULK2 PKD1 PKD1 RIPK1 RIPK1 TDGF1 TDGF1 PRKCI PRKCI PDPK1 PDPK1 PKN2 PKN2 IKBKB IKBKB VRK2 VRK2 AURKA AURKA MAPKAPK3 MAPKAPK3 PIKFYVE PIKFYVE AKT3 AKT3 IKBKE IKBKE MAPK9 MAPK9 MAPK7 MAPK7 TSSK4 TSSK4 PRKCZ PRKCZ HIPK2 HIPK2 RPS6KA3 RPS6KA3 ULK3 ULK3 CSNK1A1L CSNK1A1L CHEK2 CHEK2 PRKDC PRKDC PRKCD PRKCD MAST1 MAST1 DCLK2 DCLK2 PRKCQ PRKCQ GSK3B GSK3B CDK5 CDK5 GAS6 GAS6 ATR ATR STK32C STK32C CSNK1A1 CSNK1A1 MAPK12 MAPK12 CAMK4 CAMK4 DCLK3 DCLK3 MAPKAPK5 MAPKAPK5 PRKX PRKX TGFBR2 TGFBR2 STK38L STK38L LATS2 LATS2 SRPK2 SRPK2 MYO3B MYO3B PRKAA1 PRKAA1 TAF1 TAF1 MAPKAPK2 MAPKAPK2 PAK2 PAK2 ATM ATM LOC105573813 LOC105573813 CAMK1G CAMK1G AKT2 AKT2 SLC1A1 SLC1A1 CAMKV CAMKV MAP3K20 MAP3K20 DGKQ DGKQ BAK1 BAK1 SMG1 SMG1 TTBK1 TTBK1 DYRK1B DYRK1B RPS6KA5 RPS6KA5 TLK2 TLK2 CDK1 CDK1 EPO EPO MAP3K12 MAP3K12 MAP3K13 MAP3K13 PDK3 PDK3 HIPK3 HIPK3 HIPK4 HIPK4 MAST3 MAST3 TNKS TNKS UHMK1 UHMK1 VRK1 VRK1 SGK2 SGK2 LMTK2 LMTK2 PKN3 PKN3 PRKG2 PRKG2 BRSK1 BRSK1 CAMK2D CAMK2D MAPK3 MAPK3 VRK3 VRK3 ROCK1 ROCK1 PRKD1 PRKD1 SMTNL1 SMTNL1 SYK SYK MAPK8 MAPK8 DCLK1 DCLK1 PDGFB PDGFB WNK1 WNK1 MKNK2 MKNK2 MARK3 MARK3 MAPK14 MAPK14 PNCK PNCK TBK1 TBK1 MAST2 MAST2 MKNK1 MKNK1 BRSK2 BRSK2 MAP3K10 MAP3K10 PRKAA2 PRKAA2 PRKCE PRKCE AURKC AURKC ERN1 ERN1 CDK2 CDK2 PLK1 PLK1 MARK1 MARK1 RICTOR RICTOR CSNK1G1 CSNK1G1 ROCK2 ROCK2 MAPK10 MAPK10 CSNK2A1 CSNK2A1 CHUK CHUK BCL2 BCL2 CAB39 CAB39 NLK NLK PRKD2 PRKD2 HIPK1 HIPK1 ENSCATP00000004066 ENSCATP00000004066 SRC SRC DYRK4 DYRK4 RPS6KA6 RPS6KA6 LATS1 LATS1 MAST4 MAST4 CDK5R1 CDK5R1 RPS6KA2 RPS6KA2 ENSCATP00000044566 ENSCATP00000044566 MAP4K1 MAP4K1 STK32A STK32A STK39 STK39 GSK3A GSK3A TLK1 TLK1 CLK1 CLK1 ENSCATP00000006421 ENSCATP00000006421 LRRK2 LRRK2 GRK2 GRK2 AKT1 AKT1 MAPK13 MAPK13 PCK1 PCK1 ENSCATP00000001548 ENSCATP00000001548 MYO3A MYO3A CSNK2A2 CSNK2A2 PLK2 PLK2 RPS6KB2 RPS6KB2 MORC3 MORC3 PBK PBK NEK7 NEK7 ULK1 ULK1 CLSPN CLSPN AURKB AURKB DMPK DMPK TOP1 TOP1 DYRK1A DYRK1A NEK6 NEK6 IL24 IL24 DYRK2 DYRK2 ENSCATP00000008398 ENSCATP00000008398 PRKCB PRKCB TTBK2 TTBK2 CAMK1 CAMK1 MARK2 MARK2 PRKCA PRKCA PKN1 PKN1 ENSCATP00000014533 ENSCATP00000014533 RPS6KB1 RPS6KB1 PINK1 PINK1 ENSCATP00000010464 ENSCATP00000010464 MST1 MST1 TGFBR1 TGFBR1 EIF2AK3 EIF2AK3 TSSK6 TSSK6 MTOR MTOR MASTL MASTL NTRK2 NTRK2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CAMK1DCalcium/calmodulin dependent protein kinase ID; Belongs to the protein kinase superfamily. (385 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
SBK1Serine/threonine-protein kinase SBK1; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (424 aa)
RPS6KA4Ribosomal protein S6 kinase. (763 aa)
CDC7Protein kinase domain-containing protein. (574 aa)
ENSCATP00000016805Protein kinase domain-containing protein. (324 aa)
RPS6KA1Ribosomal protein S6 kinase. (744 aa)
STK32BSerine/threonine kinase 32B; Belongs to the protein kinase superfamily. (369 aa)
ULK2Unc-51 like autophagy activating kinase 2. (931 aa)
PKD1Polycystin 1, transient receptor potential channel interacting. (4298 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (671 aa)
TDGF1Growth factor; Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family. (182 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (690 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (534 aa)
PKN2Protein kinase N2. (983 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
VRK2VRK serine/threonine kinase 2. (507 aa)
AURKAProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (403 aa)
MAPKAPK3MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (411 aa)
PIKFYVEPhosphoinositide kinase, FYVE-type zinc finger containing. (2098 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (693 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (814 aa)
TSSK4Testis specific serine kinase 4. (338 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa)
HIPK2Homeodomain interacting protein kinase 2. (1198 aa)
RPS6KA3Ribosomal protein S6 kinase. (732 aa)
ULK3Unc-51 like kinase 3. (539 aa)
CSNK1A1LCasein kinase 1 alpha 1 like. (243 aa)
CHEK2Checkpoint kinase 2. (589 aa)
PRKDCProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4128 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
MAST1Microtubule associated serine/threonine kinase 1. (1570 aa)
DCLK2Doublecortin like kinase 2. (783 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (440 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
GAS6Growth arrest specific 6. (683 aa)
ATRATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2573 aa)
STK32CSerine/threonine kinase 32C; Belongs to the protein kinase superfamily. (485 aa)
CSNK1A1Casein kinase 1 alpha 1; Belongs to the protein kinase superfamily. (353 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
CAMK4Calcium/calmodulin dependent protein kinase IV; Belongs to the protein kinase superfamily. (473 aa)
DCLK3Doublecortin like kinase 3. (817 aa)
MAPKAPK5MAPK activated protein kinase 5. (474 aa)
PRKXProtein kinase X-linked; Belongs to the protein kinase superfamily. (358 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
STK38LNon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (470 aa)
LATS2Non-specific serine/threonine protein kinase. (1086 aa)
SRPK2SRSF protein kinase 2. (698 aa)
MYO3BMyosin IIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1329 aa)
PRKAA1Non-specific serine/threonine protein kinase. (574 aa)
TAF1Transcription initiation factor TFIID subunit. (1927 aa)
MAPKAPK2MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (400 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3073 aa)
LOC105573813Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (394 aa)
CAMK1GCalcium/calmodulin dependent protein kinase IG; Belongs to the protein kinase superfamily. (476 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
SLC1A1Solute carrier family 1 member 1. (524 aa)
CAMKVCaM kinase like vesicle associated. (501 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase 20. (788 aa)
DGKQDiacylglycerol kinase. (955 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
SMG1SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family. (3660 aa)
TTBK1Tau tubulin kinase 1. (1324 aa)
DYRK1BDual specificity tyrosine phosphorylation regulated kinase 1B. (629 aa)
RPS6KA5Non-specific serine/threonine protein kinase. (896 aa)
TLK2Tousled like kinase 2. (750 aa)
CDK1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (297 aa)
EPOErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (193 aa)
MAP3K12Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (890 aa)
MAP3K13Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (966 aa)
PDK3Protein-serine/threonine kinase. (431 aa)
HIPK3Homeodomain interacting protein kinase 3. (1215 aa)
HIPK4Homeodomain interacting protein kinase 4. (616 aa)
MAST3Microtubule associated serine/threonine kinase 3. (1311 aa)
TNKSPoly [ADP-ribose] polymerase. (1327 aa)
UHMK1U2AF homology motif kinase 1. (419 aa)
VRK1VRK serine/threonine kinase 1; Belongs to the protein kinase superfamily. (396 aa)
SGK2Serum/glucocorticoid regulated kinase 2. (413 aa)
LMTK2Lemur tyrosine kinase 2. (1501 aa)
PKN3Protein kinase N3. (889 aa)
PRKG2cGMP-dependent protein kinase. (762 aa)
BRSK1BR serine/threonine kinase 1. (794 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (533 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (364 aa)
VRK3VRK serine/threonine kinase 3. (451 aa)
ROCK1Rho associated coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1337 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (920 aa)
SMTNL1Smoothelin like 1. (496 aa)
SYKNon-specific protein-tyrosine kinase. (637 aa)
MAPK8Mitogen-activated protein kinase. (384 aa)
DCLK1Doublecortin like kinase 1. (751 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
WNK1WNK lysine deficient protein kinase 1. (2836 aa)
MKNK2MAPK interacting serine/threonine kinase 2; Belongs to the protein kinase superfamily. (465 aa)
MARK3Non-specific serine/threonine protein kinase. (846 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
PNCKPregnancy up-regulated nonubiquitous CaM kinase; Belongs to the protein kinase superfamily. (360 aa)
TBK1TANK binding kinase 1. (729 aa)
MAST2Microtubule associated serine/threonine kinase 2. (1695 aa)
MKNK1MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. (476 aa)
BRSK2BR serine/threonine kinase 2. (760 aa)
MAP3K10Mitogen-activated protein kinase kinase kinase. (952 aa)
PRKAA2Non-specific serine/threonine protein kinase. (552 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (736 aa)
AURKCAurora kinase C; Belongs to the protein kinase superfamily. (309 aa)
ERN1Endoplasmic reticulum to nucleus signaling 1. (977 aa)
CDK2Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (346 aa)
PLK1Serine/threonine-protein kinase PLK. (603 aa)
MARK1Non-specific serine/threonine protein kinase. (795 aa)
RICTORRPTOR independent companion of MTOR complex 2. (1732 aa)
CSNK1G1Casein kinase 1 gamma 1; Belongs to the protein kinase superfamily. (475 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1388 aa)
MAPK10Mitogen-activated protein kinase. (474 aa)
CSNK2A1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
CAB39Calcium binding protein 39. (341 aa)
NLKMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (527 aa)
PRKD2Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (881 aa)
HIPK1Homeodomain interacting protein kinase 1. (1210 aa)
ENSCATP00000004066Uncharacterized protein. (189 aa)
SRCTyrosine-protein kinase. (644 aa)
DYRK4Dual specificity tyrosine phosphorylation regulated kinase 4. (516 aa)
RPS6KA6Ribosomal protein S6 kinase. (745 aa)
LATS1Large tumor suppressor kinase 1. (1179 aa)
MAST4Microtubule associated serine/threonine kinase family member 4. (2655 aa)
CDK5R1Cyclin-dependent kinase 5 activator. (307 aa)
RPS6KA2Ribosomal protein S6 kinase. (758 aa)
ENSCATP00000044566Protein kinase domain-containing protein. (546 aa)
MAP4K1Mitogen-activated protein kinase kinase kinase kinase 1; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (836 aa)
STK32ASerine/threonine kinase 32A; Belongs to the protein kinase superfamily. (396 aa)
STK39Serine/threonine kinase 39. (546 aa)
GSK3AGlycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily. (483 aa)
TLK1Protein kinase domain-containing protein. (787 aa)
CLK1CDC like kinase 1. (526 aa)
ENSCATP00000006421Protein kinase domain-containing protein. (297 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (689 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
ENSCATP00000001548Protein kinase domain-containing protein. (250 aa)
MYO3AMyosin IIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1604 aa)
CSNK2A2Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (350 aa)
PLK2Serine/threonine-protein kinase PLK. (685 aa)
RPS6KB2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (497 aa)
MORC3MORC family CW-type zinc finger 3. (935 aa)
PBKPDZ binding kinase. (323 aa)
NEK7NIMA related kinase 7; Belongs to the protein kinase superfamily. (302 aa)
ULK1Unc-51 like autophagy activating kinase 1. (1038 aa)
CLSPNClaspin. (1342 aa)
AURKBAurora kinase B; Belongs to the protein kinase superfamily. (344 aa)
DMPKDM1 protein kinase. (630 aa)
TOP1DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (767 aa)
DYRK1ADual specificity tyrosine phosphorylation regulated kinase 1A. (763 aa)
NEK6NIMA related kinase 6; Belongs to the protein kinase superfamily. (347 aa)
IL24Interleukin 24. (207 aa)
DYRK2Dual specificity tyrosine phosphorylation regulated kinase 2. (601 aa)
ENSCATP00000008398CFC domain-containing protein. (170 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
TTBK2Tau tubulin kinase 2; Belongs to the intermediate filament family. (1595 aa)
CAMK1Calcium/calmodulin dependent protein kinase I; Belongs to the protein kinase superfamily. (370 aa)
MARK2Non-specific serine/threonine protein kinase. (778 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
PKN1Protein kinase N1. (949 aa)
ENSCATP00000014533Protein kinase domain-containing protein. (155 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
PINK1PTEN induced kinase 1. (581 aa)
ENSCATP00000010464Protein kinase domain-containing protein. (438 aa)
MST1Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily. (711 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (964 aa)
TSSK6Testis specific serine kinase 6; Belongs to the protein kinase superfamily. (273 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
MASTLMicrotubule associated serine/threonine kinase like. (858 aa)
NTRK2Tyrosine-protein kinase receptor. (838 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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