STRINGSTRING
THBS1 THBS1 EPHA8 EPHA8 ENSCATP00000016746 ENSCATP00000016746 NRP2 NRP2 LTBP1 LTBP1 ENSCATP00000016559 ENSCATP00000016559 ENSCATP00000016475 ENSCATP00000016475 SEC61B SEC61B IL2RG IL2RG COL1A2 COL1A2 ENSCATP00000016044 ENSCATP00000016044 ENSCATP00000015598 ENSCATP00000015598 ENSCATP00000015286 ENSCATP00000015286 GPC1 GPC1 LTBP3 LTBP3 COL3A1 COL3A1 COL4A1 COL4A1 KLB KLB TGFB3 TGFB3 IL36RN IL36RN INSR INSR ENSCATP00000007407 ENSCATP00000007407 IL2RA IL2RA LTBP4 LTBP4 TSKU TSKU EPHA7 EPHA7 IGFBP3 IGFBP3 ENSCATP00000005001 ENSCATP00000005001 NRROS NRROS NLRP7 NLRP7 ENSCATP00000004068 ENSCATP00000004068 FLT3 FLT3 ENSCATP00000003774 ENSCATP00000003774 ENSCATP00000003424 ENSCATP00000003424 TRIM16 TRIM16 HAP1 HAP1 KAZALD1 KAZALD1 PCSK6 PCSK6 WFIKKN1 WFIKKN1 ENSCATP00000001876 ENSCATP00000001876 CD36 CD36 ACVR1C ACVR1C VASN VASN PDGFA PDGFA SCN5A SCN5A IGFBP6 IGFBP6 SRPX2 SRPX2 IGFBP7 IGFBP7 NGFR NGFR EPHA2 EPHA2 API5 API5 AXL AXL RHBDF2 RHBDF2 SDCBP SDCBP TGFBR1 TGFBR1 ERBB3 ERBB3 IL9R IL9R HYAL2 HYAL2 IGF1R IGF1R PXDN PXDN COL1A1 COL1A1 IL1R2 IL1R2 ENSCATP00000044984 ENSCATP00000044984 PDGFRB PDGFRB KL KL ENSCATP00000044149 ENSCATP00000044149 IL10RA IL10RA IGFBP5 IGFBP5 FSTL4 FSTL4 FURIN FURIN IL1R1 IL1R1 IL6R IL6R ENG ENG NTRK1 NTRK1 CHRDL1 CHRDL1 COL2A1 COL2A1 ACVR1 ACVR1 FGFR1 FGFR1 SPINT3 SPINT3 COL5A1 COL5A1 RHBDF1 RHBDF1 PDGFB PDGFB KDR KDR GHRHR GHRHR CXCL13 CXCL13 CD109 CD109 LRP2 LRP2 OSMR OSMR RPS2 RPS2 IL1RN IL1RN NTRK2 NTRK2 COL6A1 COL6A1 IGF2R IGF2R TGFBR2 TGFBR2 NRP1 NRP1 IGFBP2 IGFBP2 LRRC32 LRRC32 EGFR EGFR ACVRL1 ACVRL1 IL2RB IL2RB GLG1 GLG1 IGFALS IGFALS FIBP FIBP HTRA1 HTRA1 ENSCATP00000029864 ENSCATP00000029864 FGFR4 FGFR4 ITGAV ITGAV ENSCATP00000028759 ENSCATP00000028759 FGFR2 FGFR2 ACVR2B ACVR2B ENSCATP00000028594 ENSCATP00000028594 ITGA6 ITGA6 LIFR LIFR LTBP2 LTBP2 HAX1 HAX1 ENSCATP00000027189 ENSCATP00000027189 SHC1 SHC1 S100A13 S100A13 ENSCATP00000026979 ENSCATP00000026979 ENSCATP00000026642 ENSCATP00000026642 IGFBP1 IGFBP1 TGFBR3 TGFBR3 ENSCATP00000025839 ENSCATP00000025839 CRIM1 CRIM1 FGFRL1 FGFRL1 WFIKKN2 WFIKKN2 CCN2 CCN2 LOC105585293 LOC105585293 ENSCATP00000024147 ENSCATP00000024147 FLT4 FLT4 IL6ST IL6ST TWSG1 TWSG1 IGFBP4 IGFBP4 FLT1 FLT1 ENSCATP00000021584 ENSCATP00000021584 NKD2 NKD2 CEP57 CEP57 IGFBPL1 IGFBPL1 FGFR3 FGFR3 ACVR2A ACVR2A SORT1 SORT1 CCN1 CCN1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
THBS1Thrombospondin 1. (1170 aa)
EPHA8EPH receptor A8. (1000 aa)
ENSCATP00000016746Ribosomal_S5_C domain-containing protein. (218 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (926 aa)
LTBP1Latent transforming growth factor beta binding protein 1. (1520 aa)
ENSCATP00000016559PDZ domain-containing protein. (294 aa)
ENSCATP00000016475S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (275 aa)
SEC61BProtein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (96 aa)
IL2RGFibronectin type-III domain-containing protein. (369 aa)
COL1A2Collagen type I alpha 2 chain. (1366 aa)
ENSCATP00000016044Protein kinase domain-containing protein. (357 aa)
ENSCATP00000015598Uncharacterized protein. (223 aa)
ENSCATP00000015286PDZ domain-containing protein. (251 aa)
GPC1Glypican 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (558 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1298 aa)
COL3A1Collagen type III alpha 1 chain. (1466 aa)
COL4A1Collagen type IV alpha 1 chain. (1669 aa)
KLBKlotho beta. (1044 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
IL36RNInterleukin-1. (155 aa)
INSRTyrosine-protein kinase receptor. (1339 aa)
ENSCATP00000007407PID domain-containing protein. (502 aa)
IL2RAInterleukin 2 receptor subunit alpha. (272 aa)
LTBP4Latent transforming growth factor beta binding protein 4. (1617 aa)
TSKUTsukushi, small leucine rich proteoglycan. (353 aa)
EPHA7EPH receptor A7. (998 aa)
IGFBP3Insulin like growth factor binding protein 3. (291 aa)
ENSCATP00000005001S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (233 aa)
NRROSNegative regulator of reactive oxygen species. (692 aa)
NLRP7NLR family pyrin domain containing 7. (935 aa)
ENSCATP00000004068S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (266 aa)
FLT3Fms related tyrosine kinase 3. (741 aa)
ENSCATP00000003774Uncharacterized protein. (291 aa)
ENSCATP00000003424HCLS1-associated protein X-1; Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools. (279 aa)
TRIM16Uncharacterized protein. (557 aa)
HAP1Huntingtin associated protein 1. (507 aa)
KAZALD1Kazal type serine peptidase inhibitor domain 1. (302 aa)
PCSK6Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. (934 aa)
WFIKKN1WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1. (548 aa)
ENSCATP00000001876Uncharacterized protein. (420 aa)
CD36CD36 molecule; Belongs to the CD36 family. (472 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (445 aa)
VASNVasorin. (673 aa)
PDGFAPlatelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (211 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2017 aa)
IGFBP6Insulin like growth factor binding protein 6. (239 aa)
SRPX2Sushi repeat containing protein X-linked 2. (465 aa)
IGFBP7Insulin like growth factor binding protein 7. (282 aa)
NGFRNerve growth factor receptor. (427 aa)
EPHA2EPH receptor A2. (1033 aa)
API5Apoptosis inhibitor 5. (524 aa)
AXLAXL receptor tyrosine kinase. (894 aa)
RHBDF2Rhomboid 5 homolog 2. (850 aa)
SDCBPSyndecan binding protein. (318 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
ERBB3Erb-b2 receptor tyrosine kinase 3. (1349 aa)
IL9RInterleukin 9 receptor. (514 aa)
HYAL2Hyaluronidase. (473 aa)
IGF1RTyrosine-protein kinase receptor. (1366 aa)
PXDNBeta-microseminoprotein. (1488 aa)
COL1A1Collagen type I alpha 1 chain. (1464 aa)
IL1R2Interleukin 1 receptor type 2. (398 aa)
ENSCATP00000044984S5 DRBM domain-containing protein. (230 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
KLKlotho. (1001 aa)
ENSCATP00000044149S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (202 aa)
IL10RAInterleukin 10 receptor subunit alpha. (576 aa)
IGFBP5Insulin like growth factor binding protein 5. (272 aa)
FSTL4Follistatin like 4. (842 aa)
FURINFurin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (794 aa)
IL1R1Interleukin 1 receptor type 1. (569 aa)
IL6RInterleukin 6 receptor. (452 aa)
ENGEndoglin. (658 aa)
NTRK1Tyrosine-protein kinase receptor. (796 aa)
CHRDL1Chordin like 1. (458 aa)
COL2A1Collagen type II alpha 1 chain. (1487 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
FGFR1Fibroblast growth factor receptor. (820 aa)
SPINT3Serine peptidase inhibitor, Kunitz type 3. (89 aa)
COL5A1Collagen type V alpha 1 chain. (1841 aa)
RHBDF1Rhomboid 5 homolog 1. (859 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
GHRHRGrowth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (436 aa)
CXCL13C-X-C motif chemokine. (109 aa)
CD109CD109 molecule. (1446 aa)
LRP2LDL receptor related protein 2. (4655 aa)
OSMROncostatin M receptor. (977 aa)
RPS2S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (293 aa)
IL1RNInterleukin-1. (178 aa)
NTRK2Tyrosine-protein kinase receptor. (838 aa)
COL6A1Collagen type VI alpha 1 chain. (1028 aa)
IGF2RInsulin like growth factor 2 receptor. (2445 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (926 aa)
IGFBP2Insulin like growth factor binding protein 2. (325 aa)
LRRC32Leucine rich repeat containing 32. (662 aa)
EGFRReceptor protein-tyrosine kinase. (1210 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (528 aa)
IL2RBInterleukin 2 receptor subunit beta. (551 aa)
GLG1Golgi glycoprotein 1. (1211 aa)
IGFALSInsulin like growth factor binding protein acid labile subunit. (605 aa)
FIBPFGF1 intracellular binding protein. (357 aa)
HTRA1HtrA serine peptidase 1. (481 aa)
ENSCATP00000029864S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (252 aa)
FGFR4Fibroblast growth factor receptor. (802 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1048 aa)
ENSCATP00000028759S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (271 aa)
FGFR2Fibroblast growth factor receptor. (840 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (512 aa)
ENSCATP00000028594S5 DRBM domain-containing protein. (178 aa)
ITGA6Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (1130 aa)
LIFRLIF receptor subunit alpha. (1097 aa)
LTBP2Latent transforming growth factor beta binding protein 2. (1821 aa)
HAX1HCLS1-associated protein X-1; Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools. (279 aa)
ENSCATP00000027189S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (191 aa)
SHC1SHC adaptor protein 1. (584 aa)
S100A13S100 calcium binding protein A13; Belongs to the S-100 family. (98 aa)
ENSCATP00000026979S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (218 aa)
ENSCATP00000026642S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (250 aa)
IGFBP1Insulin like growth factor binding protein 1. (281 aa)
TGFBR3Transforming growth factor beta receptor 3. (860 aa)
ENSCATP00000025839S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (227 aa)
CRIM1Cysteine rich transmembrane BMP regulator 1. (878 aa)
FGFRL1Fibroblast growth factor receptor like 1. (474 aa)
WFIKKN2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2. (576 aa)
CCN2Cellular communication network factor 2. (349 aa)
LOC105585293Uncharacterized protein. (290 aa)
ENSCATP00000024147S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (280 aa)
FLT4Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1362 aa)
IL6STInterleukin 6 signal transducer. (918 aa)
TWSG1Twisted gastrulation BMP signaling modulator 1. (223 aa)
IGFBP4Insulin like growth factor binding protein 4. (258 aa)
FLT1Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1338 aa)
ENSCATP00000021584Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (96 aa)
NKD2NKD inhibitor of WNT signaling pathway 2. (577 aa)
CEP57Centrosomal protein 57. (504 aa)
IGFBPL1Insulin like growth factor binding protein like 1. (273 aa)
FGFR3Fibroblast growth factor receptor. (809 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (514 aa)
SORT1Sortilin. (814 aa)
CCN1Cellular communication network factor 1. (381 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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