STRINGSTRING
HDAC3 HDAC3 ENSCATP00000005937 ENSCATP00000005937 LRRK2 LRRK2 ENSCATP00000006726 ENSCATP00000006726 ENSCATP00000008011 ENSCATP00000008011 BIRC3 BIRC3 CDC20 CDC20 UBE2S UBE2S UBE2N UBE2N BRCA1 BRCA1 ENSCATP00000044149 ENSCATP00000044149 SKP1 SKP1 ENSCATP00000039241 ENSCATP00000039241 ARRDC4 ARRDC4 ENSCATP00000039328 ENSCATP00000039328 ENSCATP00000040037 ENSCATP00000040037 HSPA5 HSPA5 ENSCATP00000044984 ENSCATP00000044984 FZR1 FZR1 ENSCATP00000045408 ENSCATP00000045408 ENSCATP00000013712 ENSCATP00000013712 FANCM FANCM NPM1 NPM1 ARRDC3 ARRDC3 AMER1 AMER1 COMMD1 COMMD1 GABARAP GABARAP DDX3X DDX3X CBLB CBLB CDK5RAP3 CDK5RAP3 UBE2D1 UBE2D1 KLHL40 KLHL40 WFS1 WFS1 ENSCATP00000026642 ENSCATP00000026642 ENSCATP00000026830 ENSCATP00000026830 ENSCATP00000026979 ENSCATP00000026979 CRY1 CRY1 ENSCATP00000027189 ENSCATP00000027189 SPRTN SPRTN UBE3A UBE3A CDC14B CDC14B DNAJA3 DNAJA3 FANCI FANCI ENSCATP00000028594 ENSCATP00000028594 ENSCATP00000028759 ENSCATP00000028759 PELI1 PELI1 BMI1 BMI1 AIMP2 AIMP2 ENSCATP00000015598 ENSCATP00000015598 ANGPT1 ANGPT1 ENSCATP00000016475 ENSCATP00000016475 ENSCATP00000016746 ENSCATP00000016746 DCUN1D1 DCUN1D1 RASSF5 RASSF5 NOD2 NOD2 SEPTIN4 SEPTIN4 NDFIP1 NDFIP1 PRKN PRKN PHF23 PHF23 BCL10 BCL10 PSMD10 PSMD10 MAPK9 MAPK9 ENSCATP00000020004 ENSCATP00000020004 PTTG1IP PTTG1IP SKP2 SKP2 DCUN1D4 DCUN1D4 ENSCATP00000022492 ENSCATP00000022492 KDM1A KDM1A CDC20B CDC20B HUWE1 HUWE1 ENSCATP00000024147 ENSCATP00000024147 HSPBP1 HSPBP1 TRIB3 TRIB3 INAVA INAVA MARCHF7 MARCHF7 NMI NMI GSK3A GSK3A DNAJB2 DNAJB2 RASSF1 RASSF1 ENSCATP00000040310 ENSCATP00000040310 LOC105600316 LOC105600316 ENSCATP00000040578 ENSCATP00000040578 RIPK2 RIPK2 LOC105596130 LOC105596130 RBX1 RBX1 FBXW9 FBXW9 ENSCATP00000025839 ENSCATP00000025839 MTA1 MTA1 SMAD7 SMAD7 NDFIP2 NDFIP2 DERL1 DERL1 TICAM1 TICAM1 ENSCATP00000029864 ENSCATP00000029864 SPSB4 SPSB4 ENSCATP00000031513 ENSCATP00000031513 FBXO4 FBXO4 AXIN1 AXIN1 CUL3 CUL3 PTPN22 PTPN22 BIRC2 BIRC2 SPHK1 SPHK1 MALT1 MALT1 FBXW7 FBXW7 MASTL MASTL NHLRC1 NHLRC1 ENSCATP00000000117 ENSCATP00000000117 LOC105598099 LOC105598099 PLK1 PLK1 ENSCATP00000041083 ENSCATP00000041083 PEF1 PEF1 ENSCATP00000041990 ENSCATP00000041990 PDCD6 PDCD6 RCHY1 RCHY1 TSPYL5 TSPYL5 PIN1 PIN1 FBXO33 FBXO33 MYCBP2 MYCBP2 ENSCATP00000035826 ENSCATP00000035826 RPS2 RPS2 ENSCATP00000035908 ENSCATP00000035908 WBP1L WBP1L TOPORS TOPORS LOC105575645 LOC105575645 BTRC BTRC PINK1 PINK1 XIAP XIAP ENSCATP00000011488 ENSCATP00000011488 PAXIP1 PAXIP1 RNF180 RNF180 STUB1 STUB1 DCUN1D2 DCUN1D2 LOC105583935 LOC105583935 PTEN PTEN CAV1 CAV1 TBC1D7 TBC1D7 ENSCATP00000003984 ENSCATP00000003984 ENSCATP00000004068 ENSCATP00000004068 ENSCATP00000005001 ENSCATP00000005001 PRICKLE1 PRICKLE1 ENSCATP00000003644 ENSCATP00000003644
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HDAC3Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
ENSCATP00000005937UBIQUITIN_CONJUGAT_2 domain-containing protein. (145 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
ENSCATP00000006726UBIQUITIN_CONJUGAT_2 domain-containing protein. (145 aa)
ENSCATP00000008011HECT domain-containing protein. (748 aa)
BIRC3Baculoviral IAP repeat containing 3. (604 aa)
CDC20Cell division cycle 20. (499 aa)
UBE2SUbiquitin conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (222 aa)
UBE2NUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
BRCA1Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1871 aa)
ENSCATP00000044149S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (202 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (165 aa)
ENSCATP00000039241Uncharacterized protein. (287 aa)
ARRDC4Arrestin domain containing 4. (418 aa)
ENSCATP00000039328Nucleoplasmin domain-containing protein. (209 aa)
ENSCATP00000040037HECT domain-containing protein. (694 aa)
HSPA5Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (654 aa)
ENSCATP00000044984S5 DRBM domain-containing protein. (230 aa)
FZR1Fizzy and cell division cycle 20 related 1. (587 aa)
ENSCATP00000045408DCN1-like protein. (254 aa)
ENSCATP00000013712UBIQUITIN_CONJUGAT_2 domain-containing protein. (140 aa)
FANCMFA complementation group M. (2050 aa)
NPM1Nucleophosmin 1. (294 aa)
ARRDC3Arrestin domain containing 3. (414 aa)
AMER1APC membrane recruitment protein 1. (1185 aa)
COMMD1Copper metabolism domain containing 1. (190 aa)
GABARAPUncharacterized protein. (117 aa)
DDX3XDEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family. (711 aa)
CBLBCbl proto-oncogene B. (1027 aa)
CDK5RAP3CDK5 regulatory subunit associated protein 3. (531 aa)
UBE2D1Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (148 aa)
KLHL40Kelch like family member 40. (621 aa)
WFS1Wolframin ER transmembrane glycoprotein. (891 aa)
ENSCATP00000026642S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (250 aa)
ENSCATP00000026830Uncharacterized protein. (233 aa)
ENSCATP00000026979S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (218 aa)
CRY1Cryptochrome circadian regulator 1. (586 aa)
ENSCATP00000027189S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (191 aa)
SPRTNSprT-like N-terminal domain. (488 aa)
UBE3AUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (877 aa)
CDC14BCell division cycle 14B. (498 aa)
DNAJA3DnaJ heat shock protein family (Hsp40) member A3. (480 aa)
FANCIFA complementation group I. (1328 aa)
ENSCATP00000028594S5 DRBM domain-containing protein. (178 aa)
ENSCATP00000028759S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (271 aa)
PELI1E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa)
BMI1RING-type domain-containing protein. (326 aa)
AIMP2Aminoacyl tRNA synthetase complex interacting multifunctional protein 2. (320 aa)
ENSCATP00000015598Uncharacterized protein. (223 aa)
ANGPT1Angiopoietin 1. (498 aa)
ENSCATP00000016475S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (275 aa)
ENSCATP00000016746Ribosomal_S5_C domain-containing protein. (218 aa)
DCUN1D1DCN1-like protein. (288 aa)
RASSF5Ras association domain family member 5. (418 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1044 aa)
SEPTIN4Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (985 aa)
NDFIP1Nedd4 family interacting protein 1. (221 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa)
PHF23PHD finger protein 23. (403 aa)
BCL10BCL10 immune signaling adaptor. (311 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (226 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
ENSCATP00000020004Uncharacterized protein; Belongs to the SKP1 family. (198 aa)
PTTG1IPPTTG1 interacting protein. (180 aa)
SKP2S-phase kinase associated protein 2. (437 aa)
DCUN1D4DCN1-like protein. (331 aa)
ENSCATP00000022492Uncharacterized protein. (65 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (876 aa)
CDC20BCell division cycle 20B. (519 aa)
HUWE1HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1. (4391 aa)
ENSCATP00000024147S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (280 aa)
HSPBP1HSPA (Hsp70) binding protein 1. (363 aa)
TRIB3Tribbles pseudokinase 3. (385 aa)
INAVAInnate immunity activator. (699 aa)
MARCHF7Membrane associated ring-CH-type finger 7. (704 aa)
NMIN-myc and STAT interactor. (307 aa)
GSK3AGlycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily. (483 aa)
DNAJB2DnaJ heat shock protein family (Hsp40) member B2. (277 aa)
RASSF1Ras association domain family member 1. (340 aa)
ENSCATP00000040310ANK_REP_REGION domain-containing protein. (159 aa)
LOC105600316Uncharacterized protein. (702 aa)
ENSCATP00000040578Nucleoplasmin domain-containing protein. (217 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa)
LOC105596130EF-hand domain-containing protein. (231 aa)
RBX1Ring-box 1. (108 aa)
FBXW9F-box and WD repeat domain containing 9. (458 aa)
ENSCATP00000025839S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (227 aa)
MTA1Metastasis associated 1. (775 aa)
SMAD7Mothers against decapentaplegic homolog. (483 aa)
NDFIP2Nedd4 family interacting protein 2. (336 aa)
DERL1Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (251 aa)
TICAM1Toll like receptor adaptor molecule 1. (519 aa)
ENSCATP00000029864S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (252 aa)
SPSB4SplA/ryanodine receptor domain and SOCS box containing 4. (273 aa)
ENSCATP00000031513Uncharacterized protein. (295 aa)
FBXO4F-box protein 4. (387 aa)
AXIN1Axin 1. (867 aa)
CUL3Cullin 3; Belongs to the cullin family. (768 aa)
PTPN22Protein tyrosine phosphatase non-receptor type 22. (812 aa)
BIRC2Baculoviral IAP repeat containing 2. (618 aa)
SPHK1Sphingosine kinase 1. (470 aa)
MALT1MALT1 paracaspase. (824 aa)
FBXW7F-box and WD repeat domain containing 7. (707 aa)
MASTLMicrotubule associated serine/threonine kinase like. (858 aa)
NHLRC1NHL repeat containing E3 ubiquitin protein ligase 1. (395 aa)
ENSCATP00000000117Uncharacterized protein. (93 aa)
LOC105598099UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
PLK1Serine/threonine-protein kinase PLK. (603 aa)
ENSCATP00000041083Uncharacterized protein; Belongs to the heat shock protein 70 family. (625 aa)
PEF1Penta-EF-hand domain containing 1. (283 aa)
ENSCATP00000041990Uncharacterized protein. (114 aa)
PDCD6Programmed cell death 6. (175 aa)
RCHY1Ring finger and CHY zinc finger domain containing 1. (261 aa)
TSPYL5TSPY like 5; Belongs to the nucleosome assembly protein (NAP) family. (286 aa)
PIN1Peptidyl-prolyl cis-trans isomerase. (163 aa)
FBXO33F-box protein 33. (555 aa)
MYCBP2MYC binding protein 2. (4751 aa)
ENSCATP00000035826Uncharacterized protein. (286 aa)
RPS2S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (293 aa)
ENSCATP00000035908Uncharacterized protein. (247 aa)
WBP1LWW domain binding protein 1 like. (363 aa)
TOPORSTOP1 binding arginine/serine rich protein. (1085 aa)
LOC105575645Nucleoplasmin domain-containing protein. (210 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
PINK1PTEN induced kinase 1. (581 aa)
XIAPX-linked inhibitor of apoptosis. (497 aa)
ENSCATP00000011488Uncharacterized protein. (91 aa)
PAXIP1PAX interacting protein 1. (1079 aa)
RNF180Ring finger protein 180. (592 aa)
STUB1STIP1 homology and U-box containing protein 1. (303 aa)
DCUN1D2DCN1-like protein. (259 aa)
LOC105583935UBIQUITIN_CONJUGAT_2 domain-containing protein. (87 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
TBC1D7TBC1 domain family member 7. (293 aa)
ENSCATP00000003984Uncharacterized protein. (276 aa)
ENSCATP00000004068S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (266 aa)
ENSCATP00000005001S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (233 aa)
PRICKLE1Prickle planar cell polarity protein 1. (848 aa)
ENSCATP00000003644ANK_REP_REGION domain-containing protein. (116 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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