STRINGSTRING
SCAF8 SCAF8 BRD4 BRD4 NCBP1 NCBP1 MED29 MED29 CCNT1 CCNT1 MED23 MED23 BTBD18 BTBD18 MED14 MED14 ELL ELL MED7 MED7 ENSCATP00000008199 ENSCATP00000008199 CCNT2 CCNT2 THOC1 THOC1 KAT7 KAT7 ENSCATP00000012244 ENSCATP00000012244 ENSCATP00000012690 ENSCATP00000012690 MED28 MED28 ERCC6 ERCC6 MED16 MED16 ELL2 ELL2 THOC5 THOC5 ALYREF ALYREF MED18 MED18 PWWP2B PWWP2B GTF2F1 GTF2F1 MED31 MED31 CTNNB1 CTNNB1 SUPT5H SUPT5H MED19 MED19 CDK12 CDK12 MED24 MED24 MED9 MED9 CDK13 CDK13 SUPT16H SUPT16H MED8 MED8 MED25 MED25 MED11 MED11 MED30 MED30 CCNK CCNK CBX7 CBX7 TCERG1 TCERG1 MED21 MED21 MED4 MED4 CDC73 CDC73 SUPT6H SUPT6H CDK9 CDK9 MED26 MED26 MED15 MED15 SUPT4H1 SUPT4H1 ELL3 ELL3 HMGN1 HMGN1 DDX39B DDX39B MED22 MED22 EAPP EAPP MED27 MED27
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SCAF8SR-related CTD associated factor 8. (1337 aa)
BRD4Bromodomain containing 4. (1217 aa)
NCBP1Nuclear cap binding protein subunit 1. (790 aa)
MED29Mediator complex subunit 29. (221 aa)
CCNT1Cyclin T1; Belongs to the cyclin family. (728 aa)
MED23Mediator complex subunit 23. (1374 aa)
BTBD18BTB domain containing 18. (712 aa)
MED14Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1454 aa)
ELLElongation factor for RNA polymerase II. (621 aa)
MED7Mediator of RNA polymerase II transcription subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. (232 aa)
ENSCATP00000008199Spt4 domain-containing protein. (98 aa)
CCNT2Cyclin T2; Belongs to the cyclin family. (730 aa)
THOC1THO complex 1. (651 aa)
KAT7Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (613 aa)
ENSCATP00000012244Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (417 aa)
ENSCATP00000012690Uncharacterized protein. (616 aa)
MED28Mediator complex subunit 28. (178 aa)
ERCC6ERCC excision repair 6, chromatin remodeling factor. (1495 aa)
MED16Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (959 aa)
ELL2Elongation factor for RNA polymerase II 2. (640 aa)
THOC5THO complex 5. (686 aa)
ALYREFAly/REF export factor. (290 aa)
MED18Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (208 aa)
PWWP2BPWWP domain containing 2B. (590 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (517 aa)
MED31Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (131 aa)
CTNNB1Catenin beta 1. (781 aa)
SUPT5HTranscription elongation factor SPT5. (1087 aa)
MED19Mediator of RNA polymerase II transcription subunit 19; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (261 aa)
CDK12Cyclin dependent kinase 12. (1481 aa)
MED24Mediator complex subunit 24. (1008 aa)
MED9Mediator of RNA polymerase II transcription subunit 9; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (146 aa)
CDK13Cyclin dependent kinase 13. (1511 aa)
SUPT16HSPT16 homolog, facilitates chromatin remodeling subunit. (1047 aa)
MED8Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (337 aa)
MED25Mediator complex subunit 25. (733 aa)
MED11Mediator of RNA polymerase II transcription subunit 11; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (117 aa)
MED30Mediator complex subunit 30. (178 aa)
CCNKCyclin K; Belongs to the cyclin family. (580 aa)
CBX7Chromobox 7. (251 aa)
TCERG1Transcription elongation regulator 1. (1096 aa)
MED21Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (152 aa)
MED4Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (300 aa)
CDC73Cell division cycle 73. (531 aa)
SUPT6HTranscription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1726 aa)
CDK9Cyclin dependent kinase 9; Belongs to the protein kinase superfamily. (372 aa)
MED26TFIIS N-terminal domain-containing protein. (600 aa)
MED15Mediator of RNA polymerase II transcription subunit 15; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (789 aa)
SUPT4H1Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family. (117 aa)
ELL3Elongation factor for RNA polymerase II 3. (377 aa)
HMGN1Uncharacterized protein. (116 aa)
DDX39BDExD-box helicase 39B. (425 aa)
MED22Mediator complex subunit 22. (200 aa)
EAPPE2F associated phosphoprotein. (285 aa)
MED27Mediator complex subunit 27. (311 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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