(36 nodes) Post-transcriptional gene silencing by RNA network (Cercocebus atys)

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proteins of unknown 3D structure

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Your Input:
	ENSCATP00000012892	Uncharacterized protein. (226 aa)
	WTIP	WT1 interacting protein. (419 aa)
	AGO3	Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (860 aa)
	TNRC6B	Trinucleotide repeat containing adaptor 6B. (1823 aa)
	EIF4ENIF1	Eukaryotic translation initiation factor 4E nuclear import factor 1. (985 aa)
	TNRC6A	Trinucleotide repeat containing adaptor 6A. (1974 aa)
	NCBP1	Nuclear cap binding protein subunit 1. (790 aa)
	EIF4G1	Eukaryotic translation initiation factor 4 gamma 1. (1604 aa)
	ENSCATP00000002114	Uncharacterized protein. (431 aa)
	NRDE2	Uncharacterized protein. (1164 aa)
	DDX6	DEAD-box helicase 6; Belongs to the DEAD box helicase family. (483 aa)
	LIMD1	LIM domains containing 1. (676 aa)
	AGO4	Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (861 aa)
	MARF1	Meiosis regulator and mRNA stability factor 1. (1741 aa)
	CNOT6	CCR4-NOT transcription complex subunit 6. (557 aa)
	TRIM71	Tripartite motif containing 71. (868 aa)
	ZFP36	ZFP36 ring finger protein. (332 aa)
	ZAR1L	Zygote arrest 1 like. (321 aa)
	AGO2	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (859 aa)
	MOV10L1	Mov10 like RISC complex RNA helicase 1. (1211 aa)
	CNOT8	CCR4-NOT transcription complex subunit 8. (292 aa)
	CNOT7	CCR4-NOT transcription complex subunit 7. (285 aa)
	HELZ	Helicase with zinc finger. (1943 aa)
	MOV10	Mov10 RISC complex RNA helicase. (1003 aa)
	XPO5	Exportin 5. (1204 aa)
	EIF4E2	Eukaryotic translation initiation factor 4E family member 2; Belongs to the eukaryotic initiation factor 4E family. (249 aa)
	RBM4B	RNA binding motif protein 4B. (359 aa)
	ZAR1	Zygote arrest 1. (423 aa)
	ENSCATP00000020084	Uncharacterized protein. (191 aa)
	TNRC6C	Trinucleotide repeat containing adaptor 6C. (1943 aa)
	CT55	Cancer/testis antigen 55. (264 aa)
	CNOT1	CCR4-NOT transcription complex subunit 1. (2376 aa)
	AJUBA	Ajuba LIM protein. (538 aa)
	EIF6	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] (269 aa)
	AGO1	Argonaute RISC component 1; Belongs to the argonaute family. (858 aa)
	DICER1	Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. (1920 aa)

Your Current Organism:

Cercocebus atys

NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGO1	AGO2	ENSCATP00000015086	ENSCATP00000031524	Argonaute RISC component 1; Belongs to the argonaute family.	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	0.972
AGO1	AGO3	ENSCATP00000015086	ENSCATP00000011254	Argonaute RISC component 1; Belongs to the argonaute family.	Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs.	0.834
AGO1	AGO4	ENSCATP00000015086	ENSCATP00000041561	Argonaute RISC component 1; Belongs to the argonaute family.	Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs.	0.734
AGO1	DDX6	ENSCATP00000015086	ENSCATP00000045209	Argonaute RISC component 1; Belongs to the argonaute family.	DEAD-box helicase 6; Belongs to the DEAD box helicase family.	0.734
AGO1	DICER1	ENSCATP00000015086	ENSCATP00000014802	Argonaute RISC component 1; Belongs to the argonaute family.	Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily.	0.960
AGO1	ENSCATP00000002114	ENSCATP00000015086	ENSCATP00000002114	Argonaute RISC component 1; Belongs to the argonaute family.	Uncharacterized protein.	0.602
AGO1	ENSCATP00000020084	ENSCATP00000015086	ENSCATP00000020084	Argonaute RISC component 1; Belongs to the argonaute family.	Uncharacterized protein.	0.616
AGO1	MOV10	ENSCATP00000015086	ENSCATP00000026645	Argonaute RISC component 1; Belongs to the argonaute family.	Mov10 RISC complex RNA helicase.	0.633
AGO1	TNRC6A	ENSCATP00000015086	ENSCATP00000006373	Argonaute RISC component 1; Belongs to the argonaute family.	Trinucleotide repeat containing adaptor 6A.	0.587
AGO1	TNRC6B	ENSCATP00000015086	ENSCATP00000010208	Argonaute RISC component 1; Belongs to the argonaute family.	Trinucleotide repeat containing adaptor 6B.	0.877
AGO1	XPO5	ENSCATP00000015086	ENSCATP00000025745	Argonaute RISC component 1; Belongs to the argonaute family.	Exportin 5.	0.731
AGO1	ZFP36	ENSCATP00000015086	ENSCATP00000032123	Argonaute RISC component 1; Belongs to the argonaute family.	ZFP36 ring finger protein.	0.546
AGO2	AGO1	ENSCATP00000031524	ENSCATP00000015086	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Argonaute RISC component 1; Belongs to the argonaute family.	0.972
AGO2	AGO3	ENSCATP00000031524	ENSCATP00000011254	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs.	0.951
AGO2	AGO4	ENSCATP00000031524	ENSCATP00000041561	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs.	0.909
AGO2	CNOT1	ENSCATP00000031524	ENSCATP00000017786	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	CCR4-NOT transcription complex subunit 1.	0.493
AGO2	CT55	ENSCATP00000031524	ENSCATP00000018129	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Cancer/testis antigen 55.	0.400
AGO2	DDX6	ENSCATP00000031524	ENSCATP00000045209	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	DEAD-box helicase 6; Belongs to the DEAD box helicase family.	0.863
AGO2	DICER1	ENSCATP00000031524	ENSCATP00000014802	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily.	0.983
AGO2	ENSCATP00000002114	ENSCATP00000031524	ENSCATP00000002114	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Uncharacterized protein.	0.795