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CCND1 CCND1 ATXN3 ATXN3 CREBZF CREBZF NFE2L2 NFE2L2 DAXX DAXX HSPB8 HSPB8 EIF2AK2 EIF2AK2 DERL2 DERL2 PACRG PACRG DERL3 DERL3 CREB3L1 CREB3L1 DNAJC18 DNAJC18 DNAJB12 DNAJB12 UFD1 UFD1 AMFR AMFR ENSCATP00000041083 ENSCATP00000041083 AUP1 AUP1 DDIT3 DDIT3 RNF5 RNF5 UGGT2 UGGT2 PARP16 PARP16 EIF2AK3 EIF2AK3 WFS1 WFS1 CDK5RAP3 CDK5RAP3 ENSCATP00000002949 ENSCATP00000002949 ATF4 ATF4 QRICH1 QRICH1 YOD1 YOD1 ATF6B ATF6B STUB1 STUB1 ENSCATP00000013881 ENSCATP00000013881 HSPA6 HSPA6 TBL2 TBL2 SELENOS SELENOS ERO1A ERO1A SERP1 SERP1 SDF2L1 SDF2L1 CASP12 CASP12 PRKN PRKN DAB2IP DAB2IP PMP22 PMP22 ENSCATP00000004066 ENSCATP00000004066 OPTN OPTN ERLEC1 ERLEC1 FGF21 FGF21 VCP VCP BHLHA15 BHLHA15 VAPB VAPB MBTPS1 MBTPS1 TMTC4 TMTC4 OS9 OS9 RHBDD2 RHBDD2 UMOD UMOD TOR1A TOR1A UGGT1 UGGT1 HSPA5 HSPA5 RNF126 RNF126 ERMP1 ERMP1 EIF2S1 EIF2S1 ATF6 ATF6 CUL3 CUL3 BAK1 BAK1 DERL1 DERL1 CREB3 CREB3 HSPA2 HSPA2 TMED2 TMED2 XBP1 XBP1 ATF3 ATF3 ENSCATP00000028070 ENSCATP00000028070 CREB3L2 CREB3L2 TM7SF3 TM7SF3 HSF1 HSF1 BAG6 BAG6 ERN2 ERN2 CREB3L3 CREB3L3 PTPN1 PTPN1 ERN1 ERN1 AKIRIN2 AKIRIN2 ABCB10 ABCB10 UBE2W UBE2W HERPUD2 HERPUD2 KLHL15 KLHL15 CREB3L4 CREB3L4 EP300 EP300 PACRGL PACRGL BAG3 BAG3 HDAC6 HDAC6 RHBDD1 RHBDD1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
ATXN3Ataxin 3. (366 aa)
CREBZFCREB/ATF bZIP transcription factor. (358 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (606 aa)
DAXXDeath domain associated protein. (739 aa)
HSPB8Heat shock protein family B (small) member 8; Belongs to the small heat shock protein (HSP20) family. (196 aa)
EIF2AK2Eukaryotic translation initiation factor 2 alpha kinase 2. (551 aa)
DERL2Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (265 aa)
PACRGParkin coregulated. (295 aa)
DERL3Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (238 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (519 aa)
DNAJC18DnaJ heat shock protein family (Hsp40) member C18. (358 aa)
DNAJB12DnaJ heat shock protein family (Hsp40) member B12. (409 aa)
UFD1Uncharacterized protein. (309 aa)
AMFRAutocrine motility factor receptor. (603 aa)
ENSCATP00000041083Uncharacterized protein; Belongs to the heat shock protein 70 family. (625 aa)
AUP1AUP1 lipid droplet regulating VLDL assembly factor. (410 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (169 aa)
RNF5Ring finger protein 5. (180 aa)
UGGT2UDP-glucose glycoprotein glucosyltransferase 2. (1506 aa)
PARP16Poly [ADP-ribose] polymerase. (322 aa)
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (964 aa)
WFS1Wolframin ER transmembrane glycoprotein. (891 aa)
CDK5RAP3CDK5 regulatory subunit associated protein 3. (531 aa)
ENSCATP00000002949J domain-containing protein. (310 aa)
ATF4Activating transcription factor 4. (351 aa)
QRICH1Glutamine rich 1. (777 aa)
YOD1YOD1 deubiquitinase. (348 aa)
ATF6BActivating transcription factor 6 beta. (711 aa)
STUB1STIP1 homology and U-box containing protein 1. (303 aa)
ENSCATP00000013881GOLD domain-containing protein. (188 aa)
HSPA6Heat shock protein family A (Hsp70) member 6; Belongs to the heat shock protein 70 family. (605 aa)
TBL2Transducin beta like 2. (446 aa)
SELENOSSelenoprotein S. (190 aa)
ERO1AEndoplasmic reticulum oxidoreductase 1 alpha. (459 aa)
SERP1Stress-associated endoplasmic reticulum protein; May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation. Belongs to the RAMP4 family. (72 aa)
SDF2L1Stromal cell derived factor 2 like 1. (221 aa)
CASP12Caspase 12 (gene/pseudogene); Belongs to the peptidase C14A family. (408 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa)
DAB2IPDAB2 interacting protein. (1189 aa)
PMP22Peripheral myelin protein 22; Might be involved in growth regulation, and in myelinization in the peripheral nervous system; Belongs to the PMP-22/EMP/MP20 family. (160 aa)
ENSCATP00000004066Uncharacterized protein. (189 aa)
OPTNOptineurin. (571 aa)
ERLEC1Endoplasmic reticulum lectin 1. (472 aa)
FGF21Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (806 aa)
BHLHA15Basic helix-loop-helix family member a15. (191 aa)
VAPBVAMP associated protein B and C. (243 aa)
MBTPS1Membrane bound transcription factor peptidase, site 1. (1052 aa)
TMTC4Transmembrane O-mannosyltransferase targeting cadherins 4. (764 aa)
OS9OS9 endoplasmic reticulum lectin. (725 aa)
RHBDD2Rhomboid domain containing 2. (364 aa)
UMODUromodulin. (674 aa)
TOR1ATorsin. (332 aa)
UGGT1UDP-glucose glycoprotein glucosyltransferase 1. (1555 aa)
HSPA5Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (654 aa)
RNF126Ring finger protein 126. (311 aa)
ERMP1Endoplasmic reticulum metallopeptidase 1. (906 aa)
EIF2S1Eukaryotic translation initiation factor 2 subunit alpha. (315 aa)
ATF6Activating transcription factor 6. (669 aa)
CUL3Cullin 3; Belongs to the cullin family. (768 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
DERL1Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (251 aa)
CREB3cAMP responsive element binding protein 3. (372 aa)
HSPA2Heat shock protein family A (Hsp70) member 2; Belongs to the heat shock protein 70 family. (602 aa)
TMED2Transmembrane p24 trafficking protein 2. (208 aa)
XBP1BZIP domain-containing protein. (380 aa)
ATF3Activating transcription factor 3. (181 aa)
ENSCATP00000028070Uncharacterized protein. (293 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (520 aa)
TM7SF3Transmembrane 7 superfamily member 3. (585 aa)
HSF1Heat shock transcription factor 1. (532 aa)
BAG6BCL2 associated athanogene 6. (1126 aa)
ERN2Endoplasmic reticulum to nucleus signaling 2. (926 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (461 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type. (435 aa)
ERN1Endoplasmic reticulum to nucleus signaling 1. (977 aa)
AKIRIN2Akirin 2. (205 aa)
ABCB10ATP binding cassette subfamily B member 10. (738 aa)
UBE2WUBIQUITIN_CONJUGAT_2 domain-containing protein. (191 aa)
HERPUD2HERPUD family member 2. (406 aa)
KLHL15Kelch like family member 15. (604 aa)
CREB3L4cAMP responsive element binding protein 3 like 4. (422 aa)
EP300E1A binding protein p300. (2411 aa)
PACRGLParkin coregulated like. (248 aa)
BAG3BCL2 associated athanogene 3. (575 aa)
HDAC6Histone deacetylase 6. (1217 aa)
RHBDD1Rhomboid domain containing 1. (316 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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