(14 nodes) Tetrahydrofolate interconversion network (Cercocebus atys)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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protein homology

Your Input:
	MTHFD2	Uncharacterized protein. (336 aa)
	FTCD	Formimidoyltransferase cyclodeaminase. (541 aa)
	SHMT1	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (483 aa)
	MTHFD1	Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1. (978 aa)
	ENSCATP00000005166	Josephin domain-containing protein. (106 aa)
	ENSCATP00000007813	Uncharacterized protein. (287 aa)
	MTHFD1L	Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like. (927 aa)
	SHMT2	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (504 aa)
	MTHFD2L	Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like. (347 aa)
	MTHFR	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (697 aa)
	ENSCATP00000010114	Uncharacterized protein. (248 aa)
	TYMS	Thymidylate synthetase. (308 aa)
	ST20-MTHFS	5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (231 aa)
	LOC105573483	Uncharacterized protein. (880 aa)

Your Current Organism:

Cercocebus atys

NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCATP00000005166	ENSCATP00000007813	ENSCATP00000005166	ENSCATP00000007813	Josephin domain-containing protein.	Uncharacterized protein.	0.865
ENSCATP00000005166	ENSCATP00000010114	ENSCATP00000005166	ENSCATP00000010114	Josephin domain-containing protein.	Uncharacterized protein.	0.865
ENSCATP00000005166	FTCD	ENSCATP00000005166	ENSCATP00000037967	Josephin domain-containing protein.	Formimidoyltransferase cyclodeaminase.	0.717
ENSCATP00000005166	LOC105573483	ENSCATP00000005166	ENSCATP00000029962	Josephin domain-containing protein.	Uncharacterized protein.	0.811
ENSCATP00000005166	MTHFD1	ENSCATP00000005166	ENSCATP00000004168	Josephin domain-containing protein.	Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1.	0.811
ENSCATP00000005166	MTHFD1L	ENSCATP00000005166	ENSCATP00000038825	Josephin domain-containing protein.	Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like.	0.813
ENSCATP00000005166	MTHFD2	ENSCATP00000005166	ENSCATP00000035848	Josephin domain-containing protein.	Uncharacterized protein.	0.865
ENSCATP00000005166	MTHFD2L	ENSCATP00000005166	ENSCATP00000045955	Josephin domain-containing protein.	Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like.	0.896
ENSCATP00000005166	MTHFR	ENSCATP00000005166	ENSCATP00000009025	Josephin domain-containing protein.	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	0.871
ENSCATP00000005166	SHMT2	ENSCATP00000005166	ENSCATP00000041828	Josephin domain-containing protein.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.641
ENSCATP00000005166	ST20-MTHFS	ENSCATP00000005166	ENSCATP00000016335	Josephin domain-containing protein.	5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.	0.732
ENSCATP00000005166	TYMS	ENSCATP00000005166	ENSCATP00000011882	Josephin domain-containing protein.	Thymidylate synthetase.	0.831
ENSCATP00000007813	ENSCATP00000005166	ENSCATP00000007813	ENSCATP00000005166	Uncharacterized protein.	Josephin domain-containing protein.	0.865
ENSCATP00000007813	FTCD	ENSCATP00000007813	ENSCATP00000037967	Uncharacterized protein.	Formimidoyltransferase cyclodeaminase.	0.792
ENSCATP00000007813	LOC105573483	ENSCATP00000007813	ENSCATP00000029962	Uncharacterized protein.	Uncharacterized protein.	0.676
ENSCATP00000007813	MTHFD1	ENSCATP00000007813	ENSCATP00000004168	Uncharacterized protein.	Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1.	0.676
ENSCATP00000007813	MTHFD1L	ENSCATP00000007813	ENSCATP00000038825	Uncharacterized protein.	Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like.	0.676
ENSCATP00000007813	MTHFD2L	ENSCATP00000007813	ENSCATP00000045955	Uncharacterized protein.	Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like.	0.716
ENSCATP00000007813	MTHFR	ENSCATP00000007813	ENSCATP00000009025	Uncharacterized protein.	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	0.792
ENSCATP00000007813	SHMT1	ENSCATP00000007813	ENSCATP00000001334	Uncharacterized protein.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.872