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FANCM | FA complementation group M. (2050 aa) | ||||
RAD51 | RAD51 recombinase; Belongs to the RecA family. (309 aa) | ||||
NEIL3 | Nei like DNA glycosylase 3. (602 aa) | ||||
ERCC4 | ERCC excision repair 4, endonuclease catalytic subunit. (916 aa) | ||||
ATR | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2573 aa) | ||||
FANCE | FA complementation group E. (536 aa) | ||||
FANCB | FA complementation group B. (858 aa) | ||||
HROB | Chromosome 17 open reading frame 53. (640 aa) | ||||
RAD51AP2 | RAD51 associated protein 2. (1159 aa) | ||||
RNF168 | E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recrui [...] (561 aa) | ||||
DCLRE1A | DNA cross-link repair 1A. (1040 aa) | ||||
CENPX | Centromere protein X. (133 aa) | ||||
FAAP24 | FA core complex associated protein 24. (215 aa) | ||||
FANCI | FA complementation group I. (1328 aa) | ||||
POLN | DNA polymerase nu. (869 aa) | ||||
FANCD2 | Uncharacterized protein. (1382 aa) | ||||
FANCL | FA complementation group L. (380 aa) | ||||
ERCC6L2 | Uncharacterized protein. (1455 aa) | ||||
MCM9 | Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1142 aa) | ||||
FAAP20 | Uncharacterized protein. (184 aa) | ||||
XPA | XPA, DNA damage recognition and repair factor. (273 aa) | ||||
XRCC3 | DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (381 aa) | ||||
SLX4 | SLX4 structure-specific endonuclease subunit. (1813 aa) | ||||
NUCKS1 | Nuclear casein kinase and cyclin dependent kinase substrate 1. (243 aa) | ||||
ENSCATP00000014233 | Uncharacterized protein. (276 aa) | ||||
FANCC | Fanconi anemia group C protein homolog; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1. (558 aa) | ||||
RFWD3 | Ring finger and WD repeat domain 3. (774 aa) | ||||
FANCG | FA complementation group G. (622 aa) | ||||
FANCA | FA complementation group A. (1430 aa) | ||||
FAAP100 | FA core complex associated protein 100. (881 aa) | ||||
VCP | Valosin containing protein; Belongs to the AAA ATPase family. (806 aa) | ||||
ERCC1 | ERCC excision repair 1, endonuclease non-catalytic subunit. (323 aa) | ||||
EXO5 | Exonuclease 5. (373 aa) | ||||
DCLRE1B | DNA cross-link repair 1B. (532 aa) | ||||
RAD51AP1 | RAD51 associated protein 1. (352 aa) | ||||
FAN1 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (1016 aa) |