STRINGSTRING
PRKCQ PRKCQ PLCG1 PLCG1 VAV1 VAV1 ABL1 ABL1 PAK1 PAK1 MYO1G MYO1G ENSCATP00000012914 ENSCATP00000012914 LYN LYN MS4A2 MS4A2 NR4A3 NR4A3 PIGR PIGR PTK2 PTK2 SRC SRC SOS1 SOS1 MAP2K7 MAP2K7 VAV3 VAV3 MAPK8 MAPK8 SYK SYK PLPP4 PLPP4 KIT KIT FCER1G FCER1G ENSCATP00000000012 ENSCATP00000000012 PLA2G6 PLA2G6 PRKCD PRKCD FYN FYN VAV2 VAV2 LOC105592899 LOC105592899 YES1 YES1 FCAR FCAR PLD2 PLD2 PRKCE PRKCE LOC105595672 LOC105595672 MAP3K1 MAP3K1 MAP2K4 MAP2K4 FER FER MAPK10 MAPK10 IKBKB IKBKB LCK LCK FGR FGR LOC105582717 LOC105582717 CD247 CD247 CLEC4D CLEC4D LOC105589237 LOC105589237 MAPK9 MAPK9 CLEC4E CLEC4E PLCG2 PLCG2 BTK BTK LIMK1 LIMK1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa)
VAV1Vav guanine nucleotide exchange factor 1. (856 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
PAK1Non-specific serine/threonine protein kinase. (545 aa)
MYO1GMyosin IG; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1018 aa)
ENSCATP00000012914Tyrosine-protein kinase. (399 aa)
LYNTyrosine-protein kinase. (507 aa)
MS4A2Membrane spanning 4-domains A2. (235 aa)
NR4A3Nuclear receptor subfamily 4 group A member 3. (637 aa)
PIGRPolymeric immunoglobulin receptor. (760 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1068 aa)
SRCTyrosine-protein kinase. (644 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (517 aa)
VAV3Vav guanine nucleotide exchange factor 3. (875 aa)
MAPK8Mitogen-activated protein kinase. (384 aa)
SYKNon-specific protein-tyrosine kinase. (637 aa)
PLPP4Phospholipid phosphatase 4. (271 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa)
FCER1GFc fragment of IgE receptor Ig. (111 aa)
ENSCATP00000000012Protein kinase domain-containing protein. (231 aa)
PLA2G6Phospholipase A2 group VI. (784 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
FYNTyrosine-protein kinase. (537 aa)
VAV2Vav guanine nucleotide exchange factor 2. (868 aa)
LOC105592899Uncharacterized protein. (357 aa)
YES1Tyrosine-protein kinase. (543 aa)
FCARFc fragment of IgA receptor. (279 aa)
PLD2Phospholipase. (933 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (736 aa)
LOC105595672Ig-like domain-containing protein. (621 aa)
MAP3K1Mitogen-activated protein kinase kinase kinase 1. (1508 aa)
MAP2K4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (416 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
MAPK10Mitogen-activated protein kinase. (474 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
LCKTyrosine-protein kinase. (540 aa)
FGRTyrosine-protein kinase. (496 aa)
LOC105582717Ig-like domain-containing protein. (598 aa)
CD247CD247 molecule. (165 aa)
CLEC4DC-type lectin domain family 4 member D. (215 aa)
LOC105589237Low affinity immunoglobulin gamma Fc region receptor III; Receptor for the Fc region of complexed immunoglobulins gamma. Low affinity receptor (By similarity). Binds IgG1 and IgG2. (336 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
CLEC4EC-type lectin domain family 4 member E. (219 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1236 aa)
BTKTyrosine-protein kinase. (659 aa)
LIMK1LIM domain kinase 1. (672 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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