24 items (Cercocebus atys) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MAPK8	Mitogen-activated protein kinase. (384 aa)
	FCER1G	Fc fragment of IgE receptor Ig. (111 aa)
	ENSCATP00000000012	Protein kinase domain-containing protein. (231 aa)
	LOC105582717	Ig-like domain-containing protein. (598 aa)
	MAPK10	Mitogen-activated protein kinase. (474 aa)
	FER	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
	MAP2K4	Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (416 aa)
	MAP3K1	Mitogen-activated protein kinase kinase kinase 1. (1508 aa)
	LOC105595672	Ig-like domain-containing protein. (621 aa)
	VAV2	Vav guanine nucleotide exchange factor 2. (868 aa)
	PLCG1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa)
	PRKCQ	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
	BTK	Tyrosine-protein kinase. (659 aa)
	PLCG2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1236 aa)
	MAPK9	Mitogen-activated protein kinase. (424 aa)
	IKBKB	Inhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
	VAV1	Vav guanine nucleotide exchange factor 1. (856 aa)
	LYN	Tyrosine-protein kinase. (507 aa)
	MS4A2	Membrane spanning 4-domains A2. (235 aa)
	NR4A3	Nuclear receptor subfamily 4 group A member 3. (637 aa)
	SOS1	SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa)
	MAP2K7	Mitogen-activated protein kinase kinase 7. (517 aa)
	VAV3	Vav guanine nucleotide exchange factor 3. (875 aa)
	SYK	Non-specific protein-tyrosine kinase. (637 aa)

Your Current Organism:

Cercocebus atys

NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BTK	FCER1G	ENSCATP00000020405	ENSCATP00000000510	Tyrosine-protein kinase.	Fc fragment of IgE receptor Ig.	0.498
BTK	IKBKB	ENSCATP00000020405	ENSCATP00000018811	Tyrosine-protein kinase.	Inhibitor of nuclear factor kappa B kinase subunit beta.	0.904
BTK	LYN	ENSCATP00000020405	ENSCATP00000012161	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.954
BTK	PLCG1	ENSCATP00000020405	ENSCATP00000022385	Tyrosine-protein kinase.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.925
BTK	PLCG2	ENSCATP00000020405	ENSCATP00000020331	Tyrosine-protein kinase.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.962
BTK	SOS1	ENSCATP00000020405	ENSCATP00000004020	Tyrosine-protein kinase.	SOS Ras/Rac guanine nucleotide exchange factor 1.	0.483
BTK	SYK	ENSCATP00000020405	ENSCATP00000002131	Tyrosine-protein kinase.	Non-specific protein-tyrosine kinase.	0.959
BTK	VAV1	ENSCATP00000020405	ENSCATP00000018444	Tyrosine-protein kinase.	Vav guanine nucleotide exchange factor 1.	0.843
BTK	VAV2	ENSCATP00000020405	ENSCATP00000025843	Tyrosine-protein kinase.	Vav guanine nucleotide exchange factor 2.	0.637
BTK	VAV3	ENSCATP00000020405	ENSCATP00000002336	Tyrosine-protein kinase.	Vav guanine nucleotide exchange factor 3.	0.650
ENSCATP00000000012	MAP2K7	ENSCATP00000000012	ENSCATP00000002831	Protein kinase domain-containing protein.	Mitogen-activated protein kinase kinase 7.	0.909
ENSCATP00000000012	MAP3K1	ENSCATP00000000012	ENSCATP00000037335	Protein kinase domain-containing protein.	Mitogen-activated protein kinase kinase kinase 1.	0.967
ENSCATP00000000012	MAPK10	ENSCATP00000000012	ENSCATP00000042261	Protein kinase domain-containing protein.	Mitogen-activated protein kinase.	0.976
ENSCATP00000000012	MAPK8	ENSCATP00000000012	ENSCATP00000002330	Protein kinase domain-containing protein.	Mitogen-activated protein kinase.	0.974
ENSCATP00000000012	MAPK9	ENSCATP00000000012	ENSCATP00000019872	Protein kinase domain-containing protein.	Mitogen-activated protein kinase.	0.972
ENSCATP00000000012	SYK	ENSCATP00000000012	ENSCATP00000002131	Protein kinase domain-containing protein.	Non-specific protein-tyrosine kinase.	0.438
FCER1G	BTK	ENSCATP00000000510	ENSCATP00000020405	Fc fragment of IgE receptor Ig.	Tyrosine-protein kinase.	0.498
FCER1G	LOC105582717	ENSCATP00000000510	ENSCATP00000044827	Fc fragment of IgE receptor Ig.	Ig-like domain-containing protein.	0.718
FCER1G	LOC105595672	ENSCATP00000000510	ENSCATP00000037227	Fc fragment of IgE receptor Ig.	Ig-like domain-containing protein.	0.719
FCER1G	LYN	ENSCATP00000000510	ENSCATP00000012161	Fc fragment of IgE receptor Ig.	Tyrosine-protein kinase.	0.956