Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABL1 | ATM | ENSCATP00000017539 | ENSCATP00000032722 | Tyrosine-protein kinase. | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | 0.921 |
| ABL1 | BRCA1 | ENSCATP00000017539 | ENSCATP00000044041 | Tyrosine-protein kinase. | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | 0.688 |
| ABL1 | CCND1 | ENSCATP00000017539 | ENSCATP00000034707 | Tyrosine-protein kinase. | Cyclin D1; Belongs to the cyclin family. | 0.465 |
| ABL1 | CDKN1A | ENSCATP00000017539 | ENSCATP00000004883 | Tyrosine-protein kinase. | Cyclin dependent kinase inhibitor 1A. | 0.585 |
| ABL1 | CDKN1B | ENSCATP00000017539 | ENSCATP00000033041 | Tyrosine-protein kinase. | Cyclin dependent kinase inhibitor 1B. | 0.438 |
| ABL1 | GRB2 | ENSCATP00000017539 | ENSCATP00000042750 | Tyrosine-protein kinase. | Growth factor receptor bound protein 2. | 0.986 |
| ABL1 | MAPK14 | ENSCATP00000017539 | ENSCATP00000038594 | Tyrosine-protein kinase. | Mitogen-activated protein kinase. | 0.482 |
| ABL1 | PRKDC | ENSCATP00000017539 | ENSCATP00000023124 | Tyrosine-protein kinase. | Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. | 0.404 |
| ABL1 | TP53 | ENSCATP00000017539 | ENSCATP00000032045 | Tyrosine-protein kinase. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.557 |
| ABRAXAS1 | ATM | ENSCATP00000023359 | ENSCATP00000032722 | Abraxas 1, BRCA1 A complex subunit. | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] | 0.616 |
| ABRAXAS1 | BABAM1 | ENSCATP00000023359 | ENSCATP00000016123 | Abraxas 1, BRCA1 A complex subunit. | BRISC and BRCA1 A complex member 1. | 0.997 |
| ABRAXAS1 | BABAM2 | ENSCATP00000023359 | ENSCATP00000013946 | Abraxas 1, BRCA1 A complex subunit. | BRISC and BRCA1 A complex member 2. | 0.995 |
| ABRAXAS1 | BRCA1 | ENSCATP00000023359 | ENSCATP00000044041 | Abraxas 1, BRCA1 A complex subunit. | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | 0.997 |
| ABRAXAS1 | BRCC3 | ENSCATP00000023359 | ENSCATP00000007227 | Abraxas 1, BRCA1 A complex subunit. | MPN domain-containing protein. | 0.975 |
| ABRAXAS1 | CHEK2 | ENSCATP00000023359 | ENSCATP00000023161 | Abraxas 1, BRCA1 A complex subunit. | Checkpoint kinase 2. | 0.616 |
| ABRAXAS1 | ENSCATP00000018692 | ENSCATP00000023359 | ENSCATP00000018692 | Abraxas 1, BRCA1 A complex subunit. | MPN domain-containing protein. | 0.975 |
| ABRAXAS1 | NBN | ENSCATP00000023359 | ENSCATP00000018442 | Abraxas 1, BRCA1 A complex subunit. | Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. | 0.616 |
| ABRAXAS1 | PAXIP1 | ENSCATP00000023359 | ENSCATP00000012788 | Abraxas 1, BRCA1 A complex subunit. | PAX interacting protein 1. | 0.579 |
| ABRAXAS1 | TP53BP1 | ENSCATP00000023359 | ENSCATP00000018241 | Abraxas 1, BRCA1 A complex subunit. | Tumor protein p53 binding protein 1. | 0.604 |
| ABRAXAS1 | UIMC1 | ENSCATP00000023359 | ENSCATP00000035627 | Abraxas 1, BRCA1 A complex subunit. | Ubiquitin interaction motif containing 1. | 0.993 |
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