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TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa) | ||||
PDGFA | Platelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (211 aa) | ||||
FZD5 | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa) | ||||
KIT | Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa) | ||||
TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) | ||||
FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (288 aa) | ||||
SYK | Non-specific protein-tyrosine kinase. (637 aa) | ||||
HTR2B | 5-hydroxytryptamine receptor 2B. (481 aa) | ||||
TENM1 | Teneurin transmembrane protein 1. (2732 aa) | ||||
P2RX7 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa) | ||||
LOC105584272 | KH type-2 domain-containing protein. (164 aa) | ||||
MAP2K7 | Mitogen-activated protein kinase kinase 7. (517 aa) | ||||
FZD4 | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa) | ||||
FLT3 | Fms related tyrosine kinase 3. (741 aa) | ||||
SRC | Tyrosine-protein kinase. (644 aa) | ||||
MST1R | Macrophage stimulating 1 receptor. (1426 aa) | ||||
ADAM8 | ADAM metallopeptidase domain 8. (939 aa) | ||||
ENSCATP00000005496 | Uncharacterized protein. (107 aa) | ||||
MAP3K5 | Mitogen-activated protein kinase kinase kinase 5. (1374 aa) | ||||
MIF | Macrophage migration inhibitory factor. (115 aa) | ||||
MAP4K2 | Mitogen-activated protein kinase kinase kinase kinase 2; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (825 aa) | ||||
LRRK2 | Leucine rich repeat kinase 2. (2527 aa) | ||||
KITLG | Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa) | ||||
FZD10 | Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa) | ||||
NTF3 | Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (278 aa) | ||||
INSR | Tyrosine-protein kinase receptor. (1339 aa) | ||||
ERBB2 | Receptor protein-tyrosine kinase. (1399 aa) | ||||
PTPRC | Protein tyrosine phosphatase receptor type C. (1310 aa) | ||||
TNFSF11 | TNF superfamily member 11; Belongs to the tumor necrosis factor family. (270 aa) | ||||
ENSCATP00000008398 | CFC domain-containing protein. (170 aa) | ||||
CD40 | CD40 molecule. (278 aa) | ||||
TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) | ||||
ROBO1 | Roundabout guidance receptor 1. (1684 aa) | ||||
TAOK3 | TAO kinase 3. (886 aa) | ||||
PDCD10 | Programmed cell death 10. (212 aa) | ||||
TRAF6 | TNF receptor-associated factor 6; E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, IRAK1, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. Mediates activation of NF-kappa-B and JUN. May be essential for the formation of functional osteoclasts. Seems to also play a role in dendritic cells (DCs) maturation and/or activation. Represses c-Myb-mediated transactivation, in B-lymphocytes. Adapter protein that seems to [...] (522 aa) | ||||
EDN1 | Endothelin 1. (211 aa) | ||||
PDE5A | Phosphodiesterase. (875 aa) | ||||
IL34 | Interleukin 34. (242 aa) | ||||
HRAS | HRas proto-oncogene, GTPase. (189 aa) | ||||
CSK | Tyrosine-protein kinase. (450 aa) | ||||
FZD8 | Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. (600 aa) | ||||
CD24 | CD24 molecule. (126 aa) | ||||
ENSCATP00000016044 | Protein kinase domain-containing protein. (357 aa) | ||||
WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (382 aa) | ||||
NTRK3 | Tyrosine-protein kinase receptor. (866 aa) | ||||
ERP29 | Endoplasmic reticulum resident protein 29; Does not seem to be a disulfide isomerase. (261 aa) | ||||
PAK1 | Non-specific serine/threonine protein kinase. (545 aa) | ||||
FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa) | ||||
AJUBA | Ajuba LIM protein. (538 aa) | ||||
THBS1 | Thrombospondin 1. (1170 aa) | ||||
NOD2 | Nucleotide binding oligomerization domain containing 2. (1044 aa) | ||||
IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (268 aa) | ||||
TDGF1 | Growth factor; Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family. (182 aa) | ||||
PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1018 aa) | ||||
DKK1 | Dickkopf WNT signaling pathway inhibitor 1. (266 aa) | ||||
ADAM9 | ADAM metallopeptidase domain 9. (743 aa) | ||||
TNFRSF11A | TNF receptor superfamily member 11a. (616 aa) | ||||
DAB2IP | DAB2 interacting protein. (1189 aa) | ||||
TPD52L1 | TPD52 like 1. (221 aa) | ||||
AKAP13 | A-kinase anchoring protein 13. (2816 aa) | ||||
ROR2 | Receptor tyrosine kinase like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (942 aa) | ||||
DUSP19 | Dual specificity phosphatase 19; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (217 aa) | ||||
FLT1 | Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1338 aa) | ||||
DRD4 | Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family. (415 aa) | ||||
RPS3 | Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (268 aa) | ||||
AGER | Advanced glycosylation end-product specific receptor. (403 aa) | ||||
ARHGEF5 | Rho guanine nucleotide exchange factor 5. (1597 aa) | ||||
EZH2 | Enhancer of zeste 2 polycomb repressive complex 2 subunit. (751 aa) | ||||
PDGFC | Platelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (345 aa) | ||||
EPGN | Epithelial mitogen. (154 aa) | ||||
MAGED1 | MAGE family member D1. (690 aa) | ||||
LOC105572493 | KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (242 aa) | ||||
MAP3K13 | Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (966 aa) | ||||
MAP3K4 | Mitogen-activated protein kinase kinase kinase 4. (1771 aa) | ||||
MAP3K12 | Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (890 aa) | ||||
EPHA4 | EPH receptor A4. (986 aa) | ||||
PSEN1 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa) | ||||
AXIN1 | Axin 1. (867 aa) | ||||
EGFR | Receptor protein-tyrosine kinase. (1210 aa) | ||||
DVL3 | Dishevelled segment polarity protein 3. (716 aa) | ||||
PIK3CG | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa) | ||||
FGD2 | FYVE, RhoGEF and PH domain containing 2. (655 aa) | ||||
ERN2 | Endoplasmic reticulum to nucleus signaling 2. (926 aa) | ||||
PTPN1 | Tyrosine-protein phosphatase non-receptor type. (435 aa) | ||||
PLA2G1B | Phospholipase A(2). (148 aa) | ||||
FGF18 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) | ||||
MAP2K5 | Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (472 aa) | ||||
ERN1 | Endoplasmic reticulum to nucleus signaling 1. (977 aa) | ||||
ENSCATP00000036412 | Uncharacterized protein. (144 aa) | ||||
ELANE | Elastase, neutrophil expressed; Belongs to the peptidase S1 family. (263 aa) | ||||
ENSCATP00000036866 | Uncharacterized protein. (55 aa) | ||||
EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1166 aa) | ||||
MEF2C | Myocyte enhancer factor 2C. (483 aa) | ||||
MAP3K10 | Mitogen-activated protein kinase kinase kinase. (952 aa) | ||||
MAP3K11 | Mitogen-activated protein kinase kinase kinase. (847 aa) | ||||
NEK10 | NIMA related kinase 10. (1173 aa) | ||||
ENSCATP00000038390 | Uncharacterized protein. (144 aa) | ||||
LOC105573172 | Uncharacterized protein. (906 aa) | ||||
PIK3R5 | Phosphoinositide-3-kinase regulatory subunit 5. (880 aa) | ||||
EDN3 | Endothelin 3. (230 aa) | ||||
PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa) | ||||
TGFA | Transforming growth factor alpha. (166 aa) | ||||
FGFR1 | Fibroblast growth factor receptor. (820 aa) | ||||
TLR4 | Toll like receptor 4; Belongs to the Toll-like receptor family. (843 aa) | ||||
MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (586 aa) | ||||
ENSCATP00000042935 | Ribosomal_S3_C domain-containing protein. (236 aa) | ||||
CCL19 | C-C motif chemokine. (123 aa) | ||||
RASGRP1 | RAS guanyl releasing protein 1. (837 aa) | ||||
MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa) | ||||
IRAK1 | Interleukin 1 receptor associated kinase 1. (721 aa) | ||||
DVL2 | Dishevelled segment polarity protein 2. (736 aa) | ||||
PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa) | ||||
S100A12 | S100 calcium binding protein A12; Belongs to the S-100 family. (90 aa) |