STRINGSTRING
ULK2 ULK2 ATG7 ATG7 ATG2A ATG2A WIPI1 WIPI1 WIPI2 WIPI2 LOC105596945 LOC105596945 RB1CC1 RB1CC1 ULK1 ULK1 WDR45 WDR45 ATG2B ATG2B ATG3 ATG3 ATG9B ATG9B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ULK2Unc-51 like autophagy activating kinase 2. (931 aa)
ATG7Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (703 aa)
ATG2AAutophagy related 2A. (1932 aa)
WIPI1WD repeat domain, phosphoinositide interacting 1. (446 aa)
WIPI2WD repeat domain, phosphoinositide interacting 2. (456 aa)
LOC105596945Uncharacterized protein. (418 aa)
RB1CC1RB1 inducible coiled-coil 1. (1594 aa)
ULK1Unc-51 like autophagy activating kinase 1. (1038 aa)
WDR45Uncharacterized protein. (360 aa)
ATG2BAutophagy related 2B. (2079 aa)
ATG3Autophagy-related protein 3. (314 aa)
ATG9BAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (922 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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