STRINGSTRING
CLN3 CLN3 S1PR1 S1PR1 HDAC6 HDAC6 NTSR1 NTSR1 FAS FAS SYNJ2 SYNJ2 CAVIN2 CAVIN2 SELPLG SELPLG MYO1C MYO1C GP2 GP2 APP APP ENO2 ENO2 BST2 BST2 SLC1A2 SLC1A2 CRK CRK P2RX1 P2RX1 PRNP PRNP CBLC CBLC CDH1 CDH1 UNC5B UNC5B MYOF MYOF PLLP PLLP ADGRG1 ADGRG1 PRTN3 PRTN3 PRKAR2A PRKAR2A LIPE LIPE SLC2A4 SLC2A4 STAT6 STAT6 NOS3 NOS3 TGFBR2 TGFBR2 RFTN1 RFTN1 BAALC BAALC PDPN PDPN RTN4RL1 RTN4RL1 ENSCATP00000033643 ENSCATP00000033643 CTNNA1 CTNNA1 CD177 CD177 EGFR EGFR CXADR CXADR ITGB2 ITGB2 PPP2CA PPP2CA LOC105601220 LOC105601220 BIRC2 BIRC2 VDAC2 VDAC2 EFNB1 EFNB1 SLC1A1 SLC1A1 DLL1 DLL1 ENSCATP00000031549 ENSCATP00000031549 PLVAP PLVAP RGS19 RGS19 PSEN1 PSEN1 SHH SHH SPRED1 SPRED1 STOML2 STOML2 PACSIN2 PACSIN2 ITLN1 ITLN1 MME MME NOS1 NOS1 CD4 CD4 LAMTOR3 LAMTOR3 BVES BVES CNTN1 CNTN1 ADAM17 ADAM17 SULF1 SULF1 SORBS1 SORBS1 TNFRSF1B TNFRSF1B ENSCATP00000027912 ENSCATP00000027912 ABCG2 ABCG2 AKAP6 AKAP6 HTR2A HTR2A UNC5A UNC5A ENSCATP00000027386 ENSCATP00000027386 SMURF2 SMURF2 KCNQ1 KCNQ1 CASP8 CASP8 NPHS2 NPHS2 TNR TNR ARID3A ARID3A TPP1 TPP1 RET RET ATP1A4 ATP1A4 PRKCZ PRKCZ ENSCATP00000025523 ENSCATP00000025523 CLIP3 CLIP3 ADTRP ADTRP PI4K2A PI4K2A MAL MAL PPT1 PPT1 GLIPR1L1 GLIPR1L1 OLR1 OLR1 ITGA1 ITGA1 ENSCATP00000024323 ENSCATP00000024323 FADD FADD ENSCATP00000024192 ENSCATP00000024192 FAIM2 FAIM2 IL6ST IL6ST FYN FYN RGS7 RGS7 ANK2 ANK2 LRP4 LRP4 ENSCATP00000022493 ENSCATP00000022493 LAMTOR5 LAMTOR5 MALL MALL EMP2 EMP2 ABCA1 ABCA1 RHOQ RHOQ LAT LAT CD19 CD19 TRPC4 TRPC4 LAMTOR1 LAMTOR1 ADRA1A ADRA1A KCNMA1 KCNMA1 ADD2 ADD2 MAG MAG ORAI1 ORAI1 ENSCATP00000044372 ENSCATP00000044372 ERLIN2 ERLIN2 SKAP1 SKAP1 LCK LCK PRKAR2B PRKAR2B PLSCR1 PLSCR1 MYADM MYADM FLOT2 FLOT2 BACE1 BACE1 TEX101 TEX101 ENSCATP00000016559 ENSCATP00000016559 SLC2A1 SLC2A1 STX12 STX12 TRPM8 TRPM8 MS4A1 MS4A1 DLC1 DLC1 RIPK1 RIPK1 TDGF1 TDGF1 GP6 GP6 PTK2B PTK2B RGMB RGMB IKBKB IKBKB PTCH1 PTCH1 SLC6A4 SLC6A4 MYO1A MYO1A HAS2 HAS2 BCL10 BCL10 PIKFYVE PIKFYVE ADCYAP1R1 ADCYAP1R1 SLC9A1 SLC9A1 CAV3 CAV3 TEK TEK ATP2B2 ATP2B2 MLC1 MLC1 ADCY2 ADCY2 BTK BTK LYPD4 LYPD4 RIT2 RIT2 RANGRF RANGRF ARID3C ARID3C ADCY8 ADCY8 PTGS2 PTGS2 HCK HCK EFNA5 EFNA5 DAG1 DAG1 TNFRSF1A TNFRSF1A STOML3 STOML3 CTNNB1 CTNNB1 ENSCATP00000021635 ENSCATP00000021635 TRAF2 TRAF2 CBL CBL CORO1C CORO1C ANXA13 ANXA13 SCN5A SCN5A CAVIN1 CAVIN1 CLN6 CLN6 CD8A CD8A SLC6A3 SLC6A3 ADCY1 ADCY1 F2R F2R PLPP3 PLPP3 SGCA SGCA EPHB1 EPHB1 LOC105573067 LOC105573067 CD36 CD36 HPSE HPSE CBLB CBLB KCNA5 KCNA5 EFHD2 EFHD2 P2RX7 P2RX7 ITGAM ITGAM STOML1 STOML1 CHRNB2 CHRNB2 CD79A CD79A LOC105585318 LOC105585318 CAVIN3 CAVIN3 EHD2 EHD2 BSG BSG STOM STOM PTGIS PTGIS ENSCATP00000003774 ENSCATP00000003774 STIM1 STIM1 ATP7A ATP7A SRC SRC INPP5D INPP5D LCP2 LCP2 NPC1 NPC1 VCL VCL LOC105579730 LOC105579730 SMPD2 SMPD2 AQP1 AQP1 ENSCATP00000004823 ENSCATP00000004823 DLG1 DLG1 FXYD1 FXYD1 TREM2 TREM2 TLR1 TLR1 ENSCATP00000006124 ENSCATP00000006124 LRRK2 LRRK2 MAL2 MAL2 PAG1 PAG1 RAP2B RAP2B SELE SELE LRP8 LRP8 TLR2 TLR2 INSR INSR ARC ARC JAK2 JAK2 PTPRC PTPRC GABBR1 GABBR1 CAVIN4 CAVIN4 ENSCATP00000008398 ENSCATP00000008398 BIRC3 BIRC3 NOS1AP NOS1AP KDR KDR PECAM1 PECAM1 OPRD1 OPRD1 SCARB1 SCARB1 PPP2R1B PPP2R1B IGF1R IGF1R NFAM1 NFAM1 HYAL2 HYAL2 P2RX3 P2RX3 TNFRSF10A TNFRSF10A DPP4 DPP4 GASK1A GASK1A PLPP1 PLPP1 CD48 CD48 CDH15 CDH15 LAMTOR4 LAMTOR4 TGFBR1 TGFBR1 ATP2B1 ATP2B1 TRPC5 TRPC5 RTN4RL2 RTN4RL2 NEU3 NEU3 LRP6 LRP6 ANO1 ANO1 SDCBP SDCBP MAPK3 MAPK3 LAT2 LAT2 TRADD TRADD CD55 CD55 IRS1 IRS1 RTN4R RTN4R LYN LYN LAMTOR2 LAMTOR2 PODXL PODXL LYPD6 LYPD6 EZR EZR FYB2 FYB2 LOC105601221 LOC105601221 CD14 CD14 CAV1 CAV1 SLC34A1 SLC34A1 SLC6A2 SLC6A2 KIF18A KIF18A CSK CSK ENSCATP00000014557 ENSCATP00000014557 GPC1 GPC1 ENSCATP00000014897 ENSCATP00000014897 CD24 CD24 VDAC1 VDAC1 CARD11 CARD11 ENSCATP00000015286 ENSCATP00000015286 THY1 THY1 CAV2 CAV2 ANGPT1 ANGPT1 MAPK1 MAPK1 PARK7 PARK7 FURIN FURIN FLOT1 FLOT1 ATP2B4 ATP2B4 GHSR GHSR ADRA1B ADRA1B STAMBPL1 STAMBPL1 LY6K LY6K PLPP2 PLPP2 SERPINH1 SERPINH1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CLN3Battenin. (439 aa)
S1PR1Sphingosine-1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (382 aa)
HDAC6Histone deacetylase 6. (1217 aa)
NTSR1Neurotensin receptor 1; Belongs to the G-protein coupled receptor 1 family. (418 aa)
FASTumor necrosis factor receptor superfamily member 6; Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen- stimulated suicide of mature T-cells, or both (By similarity). (331 aa)
SYNJ2Synaptojanin 2. (1496 aa)
CAVIN2Caveolae associated protein 2. (425 aa)
SELPLGSelectin P ligand. (428 aa)
MYO1CMyosin IC; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1034 aa)
GP2Glycoprotein 2. (534 aa)
APPAmyloid beta precursor protein. (770 aa)
ENO2Enolase 2. (434 aa)
BST2Bone marrow stromal cell antigen 2. (182 aa)
SLC1A2Amino acid transporter. (574 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
PRNPMajor prion protein; Its primary physiological function is unclear. Has cytoprotective activity against internal or environmental stresses. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or ZN(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan s [...] (267 aa)
CBLCCbl proto-oncogene C. (571 aa)
CDH1Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (882 aa)
UNC5BUnc-5 netrin receptor B. (904 aa)
MYOFMyoferlin. (2061 aa)
PLLPPlasmolipin. (182 aa)
ADGRG1Adhesion G protein-coupled receptor G1; Belongs to the G-protein coupled receptor 2 family. (693 aa)
PRTN3Proteinase 3; Belongs to the peptidase S1 family. (258 aa)
PRKAR2AProtein kinase cAMP-dependent type II regulatory subunit alpha. (404 aa)
LIPELipase E, hormone sensitive type. (1051 aa)
SLC2A4Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (522 aa)
STAT6Signal transducer and activator of transcription. (737 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
RFTN1Raftlin, lipid raft linker 1. (579 aa)
BAALCBAALC binder of MAP3K1 and KLF4. (180 aa)
PDPNPodoplanin. (206 aa)
RTN4RL1Reticulon 4 receptor like 1. (445 aa)
ENSCATP00000033643MARVEL domain-containing protein. (172 aa)
CTNNA1Catenin alpha 1. (906 aa)
CD177CD177 molecule. (455 aa)
EGFRReceptor protein-tyrosine kinase. (1210 aa)
CXADRCXADR Ig-like cell adhesion molecule. (365 aa)
ITGB2Integrin beta. (870 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
LOC105601220Ig-like domain-containing protein. (327 aa)
BIRC2Baculoviral IAP repeat containing 2. (618 aa)
VDAC2Voltage dependent anion channel 2. (308 aa)
EFNB1Ephrin B1; Belongs to the ephrin family. (346 aa)
SLC1A1Solute carrier family 1 member 1. (524 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
ENSCATP00000031549DJ-1_PfpI domain-containing protein. (131 aa)
PLVAPPlasmalemma vesicle associated protein. (442 aa)
RGS19Regulator of G protein signaling 19. (217 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (462 aa)
SPRED1Sprouty related EVH1 domain containing 1. (444 aa)
STOML2Stomatin like 2. (361 aa)
PACSIN2Protein kinase C and casein kinase substrate in neurons 2. (486 aa)
ITLN1Intelectin 1. (313 aa)
MMEMembrane metalloendopeptidase. (750 aa)
NOS1Nitric oxide synthase 1. (1461 aa)
CD4T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] (462 aa)
LAMTOR3Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3. (124 aa)
BVESBlood vessel epicardial substance. (360 aa)
CNTN1Contactin 1. (843 aa)
ADAM17ADAM metallopeptidase domain 17. (824 aa)
SULF1Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (869 aa)
SORBS1Sorbin and SH3 domain containing 1. (1295 aa)
TNFRSF1BTNF receptor superfamily member 1B. (462 aa)
ENSCATP00000027912Uncharacterized protein. (90 aa)
ABCG2ABC transporter domain-containing protein. (655 aa)
AKAP6A-kinase anchoring protein 6. (2318 aa)
HTR2A5-hydroxytryptamine receptor 2A. (471 aa)
UNC5AUnc-5 netrin receptor A. (898 aa)
ENSCATP00000027386Uncharacterized protein. (109 aa)
SMURF2SMAD specific E3 ubiquitin protein ligase 2. (621 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (676 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (515 aa)
NPHS2NPHS2 stomatin family member, podocin. (383 aa)
TNRTenascin R. (1358 aa)
ARID3AAT-rich interaction domain 3A. (579 aa)
TPP1Tripeptidyl peptidase 1. (572 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1115 aa)
ATP1A4Sodium/potassium-transporting ATPase subunit alpha. (1029 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa)
ENSCATP00000025523Uncharacterized protein. (91 aa)
CLIP3CAP-Gly domain containing linker protein 3. (547 aa)
ADTRPAndrogen dependent TFPI regulating protein. (248 aa)
PI4K2APhosphatidylinositol 4-kinase type 2 alpha. (479 aa)
MALMal, T cell differentiation protein. (153 aa)
PPT1Palmitoyl-protein thioesterase 1. (336 aa)
GLIPR1L1GLIPR1 like 1; Belongs to the CRISP family. (240 aa)
OLR1Oxidized low density lipoprotein receptor 1. (269 aa)
ITGA1Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1172 aa)
ENSCATP00000024323Uncharacterized protein. (271 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
ENSCATP00000024192DJ-1_PfpI domain-containing protein. (150 aa)
FAIM2Fas apoptotic inhibitory molecule 2; Belongs to the BI1 family. (315 aa)
IL6STInterleukin 6 signal transducer. (918 aa)
FYNTyrosine-protein kinase. (537 aa)
RGS7Regulator of G protein signaling 7. (487 aa)
ANK2Ankyrin 2. (3938 aa)
LRP4LDL receptor related protein 4. (1913 aa)
ENSCATP00000022493SERPIN domain-containing protein; Belongs to the serpin family. (380 aa)
LAMTOR5Uncharacterized protein. (125 aa)
MALLMal, T cell differentiation protein like. (152 aa)
EMP2Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (167 aa)
ABCA1ATP binding cassette subfamily A member 1. (2258 aa)
RHOQRas homolog family member Q. (211 aa)
LATLinker for activation of T cells. (270 aa)
CD19CD19 molecule. (531 aa)
TRPC4Transient receptor potential cation channel subfamily C member 4; Belongs to the transient receptor (TC 1.A.4) family. (978 aa)
LAMTOR1Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (161 aa)
ADRA1AAdrenoceptor alpha 1A. (463 aa)
KCNMA1Potassium calcium-activated channel subfamily M alpha 1. (1118 aa)
ADD2Adducin 2. (726 aa)
MAGMyelin associated glycoprotein. (772 aa)
ORAI1ORAI calcium release-activated calcium modulator 1. (298 aa)
ENSCATP00000044372Uncharacterized protein. (731 aa)
ERLIN2ER lipid raft associated 2. (380 aa)
SKAP1Src kinase associated phosphoprotein 1. (359 aa)
LCKTyrosine-protein kinase. (540 aa)
PRKAR2BProtein kinase cAMP-dependent type II regulatory subunit beta. (421 aa)
PLSCR1Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (313 aa)
MYADMMyeloid associated differentiation marker. (325 aa)
FLOT2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (505 aa)
BACE1Beta-secretase 1; Belongs to the peptidase A1 family. (501 aa)
TEX101Testis expressed 101. (262 aa)
ENSCATP00000016559PDZ domain-containing protein. (294 aa)
SLC2A1Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (504 aa)
STX12Syntaxin 12; Belongs to the syntaxin family. (276 aa)
TRPM8Transient receptor potential cation channel subfamily M member 8. (1115 aa)
MS4A1Membrane spanning 4-domains A1. (297 aa)
DLC1Uncharacterized protein. (498 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (671 aa)
TDGF1Growth factor; Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family. (182 aa)
GP6Glycoprotein VI platelet. (563 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1018 aa)
RGMBRepulsive guidance molecule BMP co-receptor b. (479 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
PTCH1Patched 1. (1452 aa)
SLC6A4Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (630 aa)
MYO1AMyosin IA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1043 aa)
HAS2Hyaluronan synthase 2. (552 aa)
BCL10BCL10 immune signaling adaptor. (311 aa)
PIKFYVEPhosphoinositide kinase, FYVE-type zinc finger containing. (2098 aa)
ADCYAP1R1ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. (523 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
TEKTEK receptor tyrosine kinase. (1124 aa)
ATP2B2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1270 aa)
MLC1Modulator of VRAC current 1. (366 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1052 aa)
BTKTyrosine-protein kinase. (659 aa)
LYPD4LY6/PLAUR domain containing 4. (246 aa)
RIT2Ras like without CAAX 2. (217 aa)
RANGRFRAN guanine nucleotide release factor. (186 aa)
ARID3CAT-rich interaction domain 3C. (411 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1251 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
HCKTyrosine-protein kinase. (504 aa)
EFNA5Ephrin A5; Belongs to the ephrin family. (228 aa)
DAG1Dystroglycan 1. (894 aa)
TNFRSF1ATNF receptor superfamily member 1A. (455 aa)
STOML3Stomatin like 3. (280 aa)
CTNNB1Catenin beta 1. (781 aa)
ENSCATP00000021635Uncharacterized protein. (194 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
CBLCbl proto-oncogene. (907 aa)
CORO1CCoronin; Belongs to the WD repeat coronin family. (527 aa)
ANXA13Annexin. (357 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2017 aa)
CAVIN1Caveolae associated protein 1. (391 aa)
CLN6CLN6 transmembrane ER protein. (342 aa)
CD8ACD8a molecule. (276 aa)
SLC6A3Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (620 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1115 aa)
F2RCoagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (425 aa)
PLPP3acidPPc domain-containing protein. (311 aa)
SGCASarcoglycan alpha. (387 aa)
EPHB1EPH receptor B1. (984 aa)
LOC105573067Uncharacterized protein; Belongs to the BI1 family. (304 aa)
CD36CD36 molecule; Belongs to the CD36 family. (472 aa)
HPSEHeparanase. (539 aa)
CBLBCbl proto-oncogene B. (1027 aa)
KCNA5Potassium voltage-gated channel subfamily A member 5; Belongs to the potassium channel family. (605 aa)
EFHD2EF-hand domain family member D2. (240 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
ITGAMIntegrin subunit alpha M; Belongs to the integrin alpha chain family. (1152 aa)
STOML1Stomatin like 1. (392 aa)
CHRNB2Cholinergic receptor nicotinic beta 2 subunit. (502 aa)
CD79ACD79a molecule. (225 aa)
LOC105585318Uncharacterized protein. (246 aa)
CAVIN3Caveolae associated protein 3. (295 aa)
EHD2EH domain containing 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (538 aa)
BSGBasigin (Ok blood group). (346 aa)
STOMStomatin. (288 aa)
PTGISProstacyclin synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2); Belongs to the cytochrome P450 family. (500 aa)
ENSCATP00000003774Uncharacterized protein. (291 aa)
STIM1Stromal interaction molecule 1. (784 aa)
ATP7AATPase copper transporting alpha. (1500 aa)
SRCTyrosine-protein kinase. (644 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1184 aa)
LCP2Lymphocyte cytosolic protein 2. (533 aa)
NPC1NPC intracellular cholesterol transporter 1. (1277 aa)
VCLVinculin. (1134 aa)
LOC105579730Ig-like domain-containing protein. (325 aa)
SMPD2Sphingomyelin phosphodiesterase 2. (423 aa)
AQP1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (296 aa)
ENSCATP00000004823Uncharacterized protein. (91 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (925 aa)
FXYD1FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (92 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (230 aa)
TLR1Toll-like receptor. (786 aa)
ENSCATP00000006124Uncharacterized protein. (772 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
MAL2Mal, T cell differentiation protein 2 (gene/pseudogene). (176 aa)
PAG1Phosphoprotein membrane anchor with glycosphingolipid microdomains 1. (432 aa)
RAP2BRAP2B, member of RAS oncogene family. (183 aa)
SELESelectin E. (610 aa)
LRP8LDL receptor related protein 8. (960 aa)
TLR2Toll-like receptor. (784 aa)
INSRTyrosine-protein kinase receptor. (1339 aa)
ARCActivity regulated cytoskeleton associated protein. (396 aa)
JAK2Tyrosine-protein kinase. (1137 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1310 aa)
GABBR1Gamma-aminobutyric acid type B receptor subunit 1. (1007 aa)
CAVIN4Caveolae associated protein 4. (361 aa)
ENSCATP00000008398CFC domain-containing protein. (170 aa)
BIRC3Baculoviral IAP repeat containing 3. (604 aa)
NOS1APPID domain-containing protein. (690 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
PECAM1Platelet and endothelial cell adhesion molecule 1. (721 aa)
OPRD1Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family. (372 aa)
SCARB1Scavenger receptor class B member 1; Belongs to the CD36 family. (509 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (667 aa)
IGF1RTyrosine-protein kinase receptor. (1366 aa)
NFAM1NFAT activating protein with ITAM motif 1. (271 aa)
HYAL2Hyaluronidase. (473 aa)
P2RX3P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (397 aa)
TNFRSF10ATNF receptor superfamily member 10a. (471 aa)
DPP4Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (770 aa)
GASK1AGolgi associated kinase 1A. (575 aa)
PLPP1Phospholipid phosphatase 1. (285 aa)
CD48CD48 molecule. (259 aa)
CDH15Cadherin 15; Cadherins are calcium-dependent cell adhesion proteins. (813 aa)
LAMTOR4Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4. (99 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1249 aa)
TRPC5Transient receptor potential cation channel subfamily C member 5; Belongs to the transient receptor (TC 1.A.4) family. (974 aa)
RTN4RL2Reticulon 4 receptor like 2. (259 aa)
NEU3Neuraminidase 3. (461 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
ANO1Anoctamin. (1057 aa)
SDCBPSyndecan binding protein. (318 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (364 aa)
LAT2Linker for activation of T cells family member 2. (243 aa)
TRADDTNFRSF1A associated via death domain. (308 aa)
CD55Uncharacterized protein. (581 aa)
IRS1Insulin receptor substrate 1. (1241 aa)
RTN4RReticulon 4 receptor. (522 aa)
LYNTyrosine-protein kinase. (507 aa)
LAMTOR2Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2. (135 aa)
PODXLPodocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Belongs to the podocalyxin family. (522 aa)
LYPD6LY6/PLAUR domain containing 6. (171 aa)
EZREzrin. (603 aa)
FYB2FYN binding protein 2. (729 aa)
LOC105601221Ig-like domain-containing protein. (312 aa)
CD14Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] (374 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
SLC34A1Solute carrier family 34 member 1. (639 aa)
SLC6A2Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (628 aa)
KIF18AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (897 aa)
CSKTyrosine-protein kinase. (450 aa)
ENSCATP00000014557Uncharacterized protein. (288 aa)
GPC1Glypican 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (558 aa)
ENSCATP00000014897Uncharacterized protein. (280 aa)
CD24CD24 molecule. (126 aa)
VDAC1Uncharacterized protein. (279 aa)
CARD11Caspase recruitment domain family member 11. (1154 aa)
ENSCATP00000015286PDZ domain-containing protein. (251 aa)
THY1Thy-1 cell surface antigen. (161 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
ANGPT1Angiopoietin 1. (498 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
PARK7DJ-1_PfpI domain-containing protein. (198 aa)
FURINFurin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (794 aa)
FLOT1Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (427 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1205 aa)
GHSRGrowth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
ADRA1BAdrenoceptor alpha 1B. (518 aa)
STAMBPL1STAM binding protein like 1. (461 aa)
LY6KLymphocyte antigen 6 family member K. (165 aa)
PLPP2Phospholipid phosphatase 2. (303 aa)
SERPINH1Serpin family H member 1; Belongs to the serpin family. (418 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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