STRINGSTRING
PTH PTH CREBL2 CREBL2 MEF2A MEF2A ENSCATP00000005869 ENSCATP00000005869 ITLN2 ITLN2 AKT1 AKT1 INSR INSR IRS1 IRS1 PRKCI PRKCI PTPN11 PTPN11 RHOQ RHOQ POU4F2 POU4F2 TERT TERT OSBPL8 OSBPL8 OCLN OCLN NFE2L2 NFE2L2 SORBS1 SORBS1 CAPN10 CAPN10 IRS2 IRS2 ITLN1 ITLN1 APPL1 APPL1 FGF19 FGF19 CLTCL1 CLTCL1 RNASEL RNASEL AKT2 AKT2 FGF21 FGF21 KLF15 KLF15 C1QTNF12 C1QTNF12 MAPK14 MAPK14 ADIPOQ ADIPOQ SLC1A2 SLC1A2 OPN3 OPN3 ARPP19 ARPP19 IGF1 IGF1 ENSCATP00000044421 ENSCATP00000044421 ERFE ERFE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PTHParathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (115 aa)
CREBL2cAMP responsive element binding protein like 2. (193 aa)
MEF2AMyocyte enhancer factor 2A. (504 aa)
ENSCATP00000005869Uncharacterized protein. (526 aa)
ITLN2Intelectin 2. (312 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
INSRTyrosine-protein kinase receptor. (1339 aa)
IRS1Insulin receptor substrate 1. (1241 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (690 aa)
PTPN11Protein tyrosine phosphatase non-receptor type 11. (552 aa)
RHOQRas homolog family member Q. (211 aa)
POU4F2POU domain protein. (408 aa)
TERTTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1123 aa)
OSBPL8Oxysterol-binding protein; Belongs to the OSBP family. (875 aa)
OCLNOccludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (505 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (606 aa)
SORBS1Sorbin and SH3 domain containing 1. (1295 aa)
CAPN10Calpain 10; Belongs to the peptidase C2 family. (672 aa)
IRS2Insulin receptor substrate 2. (1338 aa)
ITLN1Intelectin 1. (313 aa)
APPL1Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. (715 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
CLTCL1Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1640 aa)
RNASELRibonuclease L. (741 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
FGF21Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
KLF15Kruppel like factor 15. (416 aa)
C1QTNF12C1q and TNF related 12. (295 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (274 aa)
SLC1A2Amino acid transporter. (574 aa)
OPN3Opsin 3; Belongs to the G-protein coupled receptor 1 family. (402 aa)
ARPP19cAMP regulated phosphoprotein 19; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family. (131 aa)
IGF1Insulin like growth factor 1. (208 aa)
ENSCATP00000044421Uncharacterized protein. (441 aa)
ERFEErythroferrone. (354 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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