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| | LIAS | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (372 aa) |
| | MIF | Macrophage migration inhibitory factor. (115 aa) |
| | ALDH1A1 | Aldehyde dehydrogenase 1 family member A1; Belongs to the aldehyde dehydrogenase family. (501 aa) |
| | RBP1 | Retinol binding protein 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (197 aa) |
| | BHMT | Betaine--homocysteine S-methyltransferase. (470 aa) |
| | PCCB | Propionyl-CoA carboxylase subunit beta. (572 aa) |
| | ENSCATP00000005174 | Uncharacterized protein. (224 aa) |
| | ENSCATP00000005166 | Josephin domain-containing protein. (106 aa) |
| | OSBPL6 | Oxysterol-binding protein; Belongs to the OSBP family. (959 aa) |
| | SLC1A3 | Amino acid transporter. (542 aa) |
| | GOT1L1 | Glutamic-oxaloacetic transaminase 1 like 1. (415 aa) |
| | PAH | Phenylalanine hydroxylase. (452 aa) |
| | NOXRED1 | NADP dependent oxidoreductase domain containing 1. (293 aa) |
| | ENSCATP00000036069 | Uncharacterized protein. (416 aa) |
| | GAMT | Guanidinoacetate N-methyltransferase. (268 aa) |
| | PRKAA2 | Non-specific serine/threonine protein kinase. (552 aa) |
| | OTC | Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (321 aa) |
| | ENSCATP00000036574 | Aminotran_5 domain-containing protein. (134 aa) |
| | ELOVL5 | Elongation of very long chain fatty acids protein. (326 aa) |
| | LPL | Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (484 aa) |
| | MTAP | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (333 aa) |
| | ALOX15B | Arachidonate 15-lipoxygenase type B. (676 aa) |
| | SDS | Serine dehydratase. (328 aa) |
| | ENSCATP00000037326 | Uncharacterized protein. (270 aa) |
| | ENOPH1 | Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (261 aa) |
| | PLOD2 | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2. (758 aa) |
| | CD74 | CD74 molecule. (294 aa) |
| | ENSCATP00000037976 | Uncharacterized protein; Belongs to the fatty acid desaturase type 1 family. (321 aa) |
| | HSD17B8 | Hydroxysteroid 17-beta dehydrogenase 8. (261 aa) |
| | BHMT2 | Betaine--homocysteine S-methyltransferase 2; Involved in the regulation of homocysteine metabolism. (363 aa) |
| | PTGES2 | Prostaglandin E synthase 2. (377 aa) |
| | WDR37 | WD repeat domain 37. (482 aa) |
| | MTHFD1L | Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like. (927 aa) |
| | LOC105584566 | Uncharacterized protein. (659 aa) |
| | PRKAG2 | Protein kinase AMP-activated non-catalytic subunit gamma 2. (568 aa) |
| | DHFR | DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (187 aa) |
| | ENSCATP00000039623 | Thioesterase domain-containing protein. (126 aa) |
| | ABCD1 | ATP binding cassette subfamily D member 1. (740 aa) |
| | ACOT7 | Acyl-CoA thioesterase 7. (387 aa) |
| | FADS3 | Fatty acid desaturase 3. (445 aa) |
| | PRKAG3 | Protein kinase AMP-activated non-catalytic subunit gamma 3. (489 aa) |
| | TECR | S5A_REDUCTASE domain-containing protein. (315 aa) |
| | ALOXE3 | Arachidonate lipoxygenase 3. (711 aa) |
| | GSTM2 | Glutathione S-transferase. (222 aa) |
| | ELOVL6 | Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] (265 aa) |
| | ENSCATP00000041705 | Uncharacterized protein. (296 aa) |
| | HNF1A | HNF1 homeobox A. (662 aa) |
| | SHMT2 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (504 aa) |
| | CTH | Cystathionine gamma-lyase. (405 aa) |
| | FADS2 | Fatty acid desaturase 2. (444 aa) |
| | GAD2 | Glutamate decarboxylase 2. (585 aa) |
| | LTA4H | Leukotriene A4 hydrolase. (587 aa) |
| | MLYCD | Malonyl-CoA decarboxylase. (493 aa) |
| | OSBPL3 | Oxysterol-binding protein; Belongs to the OSBP family. (887 aa) |
| | ILVBL | IlvB acetolactate synthase like; Belongs to the TPP enzyme family. (635 aa) |
| | RGN | Regucalcin. (299 aa) |
| | MECR | Mitochondrial trans-2-enoyl-CoA reductase. (373 aa) |
| | OAT | Ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (439 aa) |
| | BCAT1 | Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (462 aa) |
| | DHRS9 | Dehydrogenase/reductase 9; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (377 aa) |
| | ENSCATP00000043788 | CS domain-containing protein. (127 aa) |
| | PECR | Peroxisomal trans-2-enoyl-CoA reductase. (310 aa) |
| | TMED8 | Transmembrane p24 trafficking protein family member 8. (326 aa) |
| | BRCA1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1871 aa) |
| | CBR4 | Carbonyl reductase 4. (237 aa) |
| | ABHD1 | Abhydrolase domain containing 1. (404 aa) |
| | PSAT1 | Phosphoserine aminotransferase. (370 aa) |
| | GLUD2 | Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (502 aa) |
| | NLRC4 | NLR family CARD domain containing 4. (1024 aa) |
| | MGST2 | Microsomal glutathione S-transferase 2. (147 aa) |
| | ABHD3 | Abhydrolase domain containing 3. (350 aa) |
| | DECR2 | 2,4-dienoyl-CoA reductase 2. (289 aa) |
| | ALDH18A1 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. (804 aa) |
| | MTRR | 5-methyltetrahydrofolate-homocysteine methyltransferase reductase. (698 aa) |
| | PYCR2 | Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (320 aa) |
| | HACD1 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (288 aa) |
| | ALDH8A1 | Aldehyde dehydrogenase 8 family member A1; Belongs to the aldehyde dehydrogenase family. (487 aa) |
| | MTHFD2L | Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like. (347 aa) |
| | DEGS1 | Delta 4-desaturase, sphingolipid 1. (323 aa) |
| | ALOX15 | Lipoxygenase domain-containing protein. (325 aa) |
| | CBS | PALP domain-containing protein. (548 aa) |
| | SLC27A2 | Solute carrier family 27 member 2. (620 aa) |
| | FADS1 | Fatty acid desaturase 1. (444 aa) |
| | XBP1 | BZIP domain-containing protein. (380 aa) |
| | QKI | QKI, KH domain containing RNA binding. (342 aa) |
| | PLA2G10 | Phospholipase A(2). (165 aa) |
| | GOT2 | Aspartate aminotransferase. (407 aa) |
| | KMO | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract. (470 aa) |
| | LOC105571706 | Uncharacterized protein. (455 aa) |
| | GPX4 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (233 aa) |
| | CYP7B1 | Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family. (505 aa) |
| | GOT1 | Aspartate aminotransferase. (413 aa) |
| | ELOVL7 | Elongation of very long chain fatty acids protein 7; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0 [...] (281 aa) |
| | LIPI | Lipase I. (480 aa) |
| | ENSCATP00000026831 | Uncharacterized protein. (339 aa) |
| | PLA2G4F | Phospholipase A2. (849 aa) |
| | SCP2 | Sterol carrier protein 2; Belongs to the thiolase-like superfamily. Thiolase family. (540 aa) |
| | FA2H | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (372 aa) |
| | FASN | Fatty acid synthase. (2511 aa) |
| | HTD2 | Hydroxyacyl-thioester dehydratase type 2. (162 aa) |
| | CYP8B1 | Cytochrome P450 family 8 subfamily B member 1; Belongs to the cytochrome P450 family. (495 aa) |
| | ABCD3 | ATP binding cassette subfamily D member 3. (659 aa) |
| | ACACA | Acetyl-CoA carboxylase alpha. (2389 aa) |
| | ENSCATP00000024985 | PNP_UDP_1 domain-containing protein. (241 aa) |
| | CYP7A1 | Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (504 aa) |
| | PLA2G5 | Phospholipase A(2). (138 aa) |
| | ENSCATP00000024192 | DJ-1_PfpI domain-containing protein. (150 aa) |
| | ELOVL4 | Elongation of very long chain fatty acids protein 4; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane [...] (314 aa) |
| | ACLY | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. (1155 aa) |
| | ASNSD1 | Glutamine amidotransferase type-2 domain-containing protein. (643 aa) |
| | AMACR | Alpha-methylacyl-CoA racemase. (382 aa) |
| | ALOX12B | Arachidonate 12-lipoxygenase, 12R type. (701 aa) |
| | ENSCATP00000023477 | Uncharacterized protein. (452 aa) |
| | PRKAG1 | Protein kinase AMP-activated non-catalytic subunit gamma 1. (333 aa) |
| | GLS | Glutaminase. (669 aa) |
| | ELOVL2 | Elongation of very long chain fatty acids protein 2; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate to the production [...] (296 aa) |
| | ASAH2 | Neutral ceramidase. (780 aa) |
| | MGLL | Monoglyceride lipase. (313 aa) |
| | CYP39A1 | Cytochrome P450 family 39 subfamily A member 1; Belongs to the cytochrome P450 family. (506 aa) |
| | ARMC7 | Armadillo repeat containing 7. (198 aa) |
| | HAO1 | Hydroxyacid oxidase 1. (409 aa) |
| | HSD17B10 | Hydroxysteroid 17-beta dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (261 aa) |
| | PHGDH | Phosphoglycerate dehydrogenase. (545 aa) |
| | LOC105573483 | Uncharacterized protein. (880 aa) |
| | SRR | Serine racemase. (339 aa) |
| | BAAT | Bile acid-CoA:amino acid N-acyltransferase. (418 aa) |
| | ENSCATP00000021931 | Uncharacterized protein. (68 aa) |
| | ENSCATP00000021591 | Uncharacterized protein; Belongs to the glutamine synthetase family. (225 aa) |
| | ACMSD | 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily. (336 aa) |
| | PKLR | Pyruvate kinase; Belongs to the pyruvate kinase family. (574 aa) |
| | PTGS2 | Prostaglandin-endoperoxide synthase 2. (604 aa) |
| | SCD | Uncharacterized protein; Belongs to the fatty acid desaturase type 1 family. (359 aa) |
| | PCBD1 | Pterin-4 alpha-carbinolamine dehydratase 1. (104 aa) |
| | DPYD | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. (1035 aa) |
| | EDN2 | Endothelin 2. (178 aa) |
| | ACSBG2 | Acyl-CoA synthetase bubblegum family member 2. (666 aa) |
| | GATD1 | Glutamine amidotransferase like class 1 domain containing 1. (234 aa) |
| | ENSCATP00000019895 | DHFR domain-containing protein. (132 aa) |
| | BCAT2 | Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (432 aa) |
| | OSBPL7 | Oxysterol-binding protein; Belongs to the OSBP family. (842 aa) |
| | LIPG | Lipase G, endothelial type. (500 aa) |
| | CRABP2 | Cellular retinoic acid binding protein 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (138 aa) |
| | UROS | Uroporphyrinogen III synthase. (236 aa) |
| | ENSCATP00000019334 | Uncharacterized protein. (425 aa) |
| | IDO1 | Indoleamine 2,3-dioxygenase 1. (403 aa) |
| | CPS1 | Carbamoyl-phosphate synthase 1. (1507 aa) |
| | OXSM | 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial; May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function. Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (460 aa) |
| | DAGLB | Diacylglycerol lipase beta. (711 aa) |
| | ABAT | 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (509 aa) |
| | LOC105576140 | Uncharacterized protein; Belongs to the cytochrome P450 family. (490 aa) |
| | GSTP1 | Glutathione S-transferase pi 1; Belongs to the GST superfamily. (210 aa) |
| | CARNS1 | Carnosine synthase 1. (950 aa) |
| | UPB1 | Beta-ureidopropionase 1. (386 aa) |
| | APIP | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death; Belongs to the aldolase class II family. MtnB subfamily. (249 aa) |
| | PTGES | Prostaglandin E synthase. (152 aa) |
| | ENSCATP00000017090 | DHFR domain-containing protein. (153 aa) |
| | HPGDS | Hematopoietic prostaglandin D synthase; Belongs to the GST superfamily. (199 aa) |
| | PARK7 | DJ-1_PfpI domain-containing protein. (198 aa) |
| | ASNS | Asparagine synthetase [glutamine-hydrolyzing]. (561 aa) |
| | PRXL2B | Peroxiredoxin like 2B. (198 aa) |
| | PLOD3 | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3. (737 aa) |
| | ACSF3 | Acyl-CoA synthetase family member 3. (576 aa) |
| | GSTM1 | Glutathione S-transferase mu 1; Belongs to the GST superfamily. (236 aa) |
| | ACSM1 | Acyl-CoA synthetase medium chain family member 1. (475 aa) |
| | KYNU | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity. Belongs to the kynureninase family. (440 aa) |
| | ACSS1 | Acetyl-coenzyme A synthetase. (688 aa) |
| | ACACB | Acetyl-CoA carboxylase beta. (2458 aa) |
| | PNPLA8 | Patatin like phospholipase domain containing 8. (782 aa) |
| | ENSCATP00000031469 | Uncharacterized protein. (230 aa) |
| | ENSCATP00000031549 | DJ-1_PfpI domain-containing protein. (131 aa) |
| | TMEM196 | Transmembrane protein 196. (185 aa) |
| | HSD17B12 | Hydroxysteroid 17-beta dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (312 aa) |
| | PLP1 | Proteolipid protein 1. (277 aa) |
| | OSBP | Oxysterol-binding protein; Belongs to the OSBP family. (682 aa) |
| | PYCARD | PYD and CARD domain containing. (195 aa) |
| | SUGCT | Succinyl-CoA:glutarate-CoA transferase. (391 aa) |
| | OSBPL1A | Oxysterol-binding protein; Belongs to the OSBP family. (949 aa) |
| | GLS2 | Glutaminase 2. (602 aa) |
| | ACOT8 | Acyl-CoA thioesterase 8. (319 aa) |
| | LIPC | Lipase C, hepatic type. (500 aa) |
| | AKR1D1 | Aldo-keto reductase family 1 member D1. (326 aa) |
| | AKR1A1 | Aldo-keto reductase family 1 member A1. (325 aa) |
| | PRKAA1 | Non-specific serine/threonine protein kinase. (574 aa) |
| | ACSM4 | Acyl-CoA synthetase medium chain family member 4. (557 aa) |
| | AGXT2 | Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (490 aa) |
| | ENSCATP00000033897 | Uncharacterized protein. (324 aa) |
| | LIPH | Lipase H. (451 aa) |
| | ASL | Argininosuccinate lyase. (494 aa) |
| | PLA2G1B | Phospholipase A(2). (148 aa) |
| | NDUFAB1 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (156 aa) |
| | LGSN | Lengsin, lens protein with glutamine synthetase domain; Belongs to the glutamine synthetase family. (507 aa) |
| | PRKAB2 | Protein kinase AMP-activated non-catalytic subunit beta 2. (272 aa) |
| | LOC105576414 | DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (187 aa) |
| | ENSCATP00000000373 | Thioesterase domain-containing protein. (116 aa) |
| | PTGS1 | Prostaglandin-endoperoxide synthase 1. (632 aa) |
| | HACD4 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (232 aa) |
| | SHMT1 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (483 aa) |
| | NAIP | NLR family apoptosis inhibitory protein. (1403 aa) |
| | LOC105599372 | Uncharacterized protein. (564 aa) |
| | SYK | Non-specific protein-tyrosine kinase. (637 aa) |
| | TBXAS1 | Thromboxane A synthase 1; Belongs to the cytochrome P450 family. (580 aa) |
| | SLC27A5 | Solute carrier family 27 member 5. (690 aa) |
| | TECRL | Trans-2,3-enoyl-CoA reductase like. (363 aa) |
| | PRG3 | Proteoglycan 3, pro eosinophil major basic protein 2. (225 aa) |
| | GATM | Glycine amidinotransferase. (423 aa) |
| | CYP46A1 | Cytochrome P450 family 46 subfamily A member 1; Belongs to the cytochrome P450 family. (500 aa) |
| | OSBPL2 | Oxysterol-binding protein; Belongs to the OSBP family. (480 aa) |
| | NAGS | N-acetylglutamate synthase. (534 aa) |
| | HSD3B7 | Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7; Belongs to the 3-beta-HSD family. (369 aa) |
| | ASS1 | Uncharacterized protein. (412 aa) |
| | LOC105600808 | Cytochrome b5 heme-binding domain-containing protein. (484 aa) |
| | PTGIS | Prostacyclin synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2); Belongs to the cytochrome P450 family. (500 aa) |
| | GLUL | Gln_synt_b-grasp domain-containing protein. (198 aa) |
| | ADI1 | 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Belongs to the acireductone dioxygenase (ARD) family. (179 aa) |
| | MTHFD1 | Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1. (978 aa) |
| | THNSL1 | Threonine synthase like 1. (743 aa) |
| | ENSCATP00000015130 | Lyase_1 domain-containing protein. (134 aa) |
| | MTR | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1268 aa) |
| | MCAT | Malonyl-CoA-acyl carrier protein transacylase. (390 aa) |
| | FADS6 | Fatty acid desaturase 6. (218 aa) |
| | PYCR3 | Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (278 aa) |
| | THNSL2 | Threonine synthase like 2. (458 aa) |
| | CASP1 | Caspase 1; Belongs to the peptidase C14A family. (441 aa) |
| | ACSM5 | Acyl-CoA synthetase medium chain family member 5. (580 aa) |
| | LOC105591424 | ELFV_dehydrog domain-containing protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (558 aa) |
| | LOC105579288 | Uncharacterized protein; Belongs to the cytochrome P450 family. (217 aa) |
| | EDN1 | Endothelin 1. (211 aa) |
| | PSPH | Phosphoserine phosphatase. (225 aa) |
| | ENSCATP00000012880 | DHFR domain-containing protein. (145 aa) |
| | ENSCATP00000012807 | DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (175 aa) |
| | ENSCATP00000012773 | DHFR domain-containing protein. (189 aa) |
| | HACD3 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (400 aa) |
| | HAAO | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. (286 aa) |
| | ENSCATP00000012114 | Aminotran_5 domain-containing protein. (341 aa) |
| | ABCB11 | ATP binding cassette subfamily B member 11. (1317 aa) |
| | ENSCATP00000011902 | Uncharacterized protein. (314 aa) |
| | HSDL1 | Hydroxysteroid dehydrogenase like 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (330 aa) |
| | ALOX5 | Arachidonate 5-lipoxygenase. (674 aa) |
| | ALOX5AP | Arachidonate 5-lipoxygenase activating protein. (218 aa) |
| | CAD | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. (2225 aa) |
| | UGDH | UDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (494 aa) |
| | ELOVL3 | Elongation of very long chain fatty acids protein 3; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precurs [...] (270 aa) |
| | ENSCATP00000011155 | S5A_REDUCTASE domain-containing protein. (273 aa) |
| | GGT6 | Gamma-glutamyltransferase 6. (499 aa) |
| | PER2 | Period circadian regulator 2. (1254 aa) |
| | MRI1 | Methylthioribose-1-phosphate isomerase 1; Belongs to the eIF-2B alpha/beta/delta subunits family. (324 aa) |
| | SCD5 | Stearoyl-CoA desaturase 5; Belongs to the fatty acid desaturase type 1 family. (330 aa) |
| | ENSCATP00000010880 | Uncharacterized protein. (333 aa) |
| | ALOX12 | Arachidonate 12-lipoxygenase, 12S type. (663 aa) |
| | PRKAB1 | Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa) |
| | LTC4S | Leukotriene C4 synthase. (150 aa) |
| | PCBD2 | Pterin-4 alpha-carbinolamine dehydratase 2. (130 aa) |
| | AKR1C3 | Aldo-keto reductase family 1 member C3. (274 aa) |
| | ALDH1A3 | Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family. (512 aa) |
| | GGT5 | Gamma-glutamyltransferase 5. (586 aa) |
| | HACD2 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (254 aa) |
| | ELOVL1 | Elongation of very long chain fatty acids protein. (286 aa) |
| | ACSM3 | Acyl-CoA synthetase medium chain family member 3. (586 aa) |
| | PYCR1 | Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (346 aa) |
| | GGT1 | Uncharacterized protein. (567 aa) |
| | MGST3 | Microsomal glutathione S-transferase 3. (166 aa) |
| | PLA2G4A | Phospholipase A2. (749 aa) |
| | AASS | Aminoadipate-semialdehyde synthase. (925 aa) |
| | ENSCATP00000007553 | DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (179 aa) |
| | LOC105576141 | Uncharacterized protein. (393 aa) |
| | LOC105586584 | Uncharacterized protein. (577 aa) |
| | ENSCATP00000007363 | Uncharacterized protein. (150 aa) |
| | RDH10 | Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa) |
| | SDSL | Serine dehydratase like. (329 aa) |
| | CYP27A1 | Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family. (531 aa) |
| | GAD1 | Glutamate decarboxylase 1. (594 aa) |
| | PTGDS | Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (190 aa) |
| | GGT7 | Gamma-glutamyltransferase 7. (664 aa) |
