39 items (Cercocebus atys) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FBXW11	F-box and WD repeat domain containing 11. (563 aa)
	KIF13A	Kinesin family member 13A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1763 aa)
	KIF5B	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (964 aa)
	NDE1	NudE neurodevelopment protein 1. (368 aa)
	HAP1	Huntingtin associated protein 1. (507 aa)
	AP3M1	AP-3 complex subunit mu-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes; Belongs to the adaptor complexes medium subunit family. (418 aa)
	BLOC1S3	Biogenesis of lysosome-related organelles complex 1 subunit 3; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO). Belongs to the BLOC1S3 family. (200 aa)
	KIF3B	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (747 aa)
	BLOC1S4	Biogenesis of lysosomal organelles complex 1 subunit 4. (216 aa)
	TRAK1	Trafficking kinesin protein 1. (957 aa)
	ENSCATP00000011418	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (70 aa)
	RAB1A	Uncharacterized protein. (217 aa)
	AP3B2	AP-3 complex subunit beta. (1102 aa)
	AP3S1	Adaptor related protein complex 3 subunit sigma 1. (193 aa)
	TRIM46	Tripartite motif containing 46. (759 aa)
	FYCO1	FYVE and coiled-coil domain containing 1. (1498 aa)
	BICDL1	BICD family like cargo adaptor 1. (572 aa)
	DTNBP1	Dystrobrevin binding protein 1. (305 aa)
	DYNC1H1	Dynein cytoplasmic 1 heavy chain 1. (4673 aa)
	AP3D1	AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane. (1213 aa)
	BLOC1S2	Biogenesis of lysosomal organelles complex 1 subunit 2. (142 aa)
	KIF1C	Kinesin family member 1C; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1124 aa)
	TRAK2	Trafficking kinesin protein 2. (914 aa)
	PRKCZ	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa)
	DYNC1I1	Dynein cytoplasmic 1 intermediate chain 1. (628 aa)
	KIF1A	Kinesin family member 1A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1787 aa)
	AP3B1	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1094 aa)
	ENSCATP00000033638	Uncharacterized protein. (198 aa)
	BLOC1S6	Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...] (172 aa)
	ENSCATP00000034500	Uncharacterized protein. (464 aa)
	HTT	Huntingtin. (3113 aa)
	LOC105594535	Clat_adaptor_s domain-containing protein. (203 aa)
	KIFAP3	Kinesin associated protein 3. (734 aa)
	BICDL2	BICD family like cargo adaptor 2. (507 aa)
	AP3M2	AP-3 complex subunit mu-2. (418 aa)
	BLOC1S5	Biogenesis of lysosome-related organelles complex 1 subunit 5; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO). (187 aa)
	CLN3	Battenin. (439 aa)
	SNAPIN	SNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (136 aa)
	RASGRP1	RAS guanyl releasing protein 1. (837 aa)

Your Current Organism:

Cercocebus atys

NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AP3B1	AP3B2	ENSCATP00000029618	ENSCATP00000013958	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.	AP-3 complex subunit beta.	0.929
AP3B1	AP3D1	ENSCATP00000029618	ENSCATP00000019259	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.	AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane.	0.997
AP3B1	AP3M1	ENSCATP00000029618	ENSCATP00000003977	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.	AP-3 complex subunit mu-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes; Belongs to the adaptor complexes medium subunit family.	0.997
AP3B1	AP3M2	ENSCATP00000029618	ENSCATP00000038715	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.	AP-3 complex subunit mu-2.	0.992
AP3B1	AP3S1	ENSCATP00000029618	ENSCATP00000015103	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.	Adaptor related protein complex 3 subunit sigma 1.	0.983
AP3B1	BLOC1S3	ENSCATP00000029618	ENSCATP00000004129	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.	Biogenesis of lysosome-related organelles complex 1 subunit 3; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO). Belongs to the BLOC1S3 family.	0.550
AP3B1	BLOC1S6	ENSCATP00000029618	ENSCATP00000034303	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.	Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...]	0.468
AP3B1	DTNBP1	ENSCATP00000029618	ENSCATP00000018062	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.	Dystrobrevin binding protein 1.	0.491
AP3B1	LOC105594535	ENSCATP00000029618	ENSCATP00000035719	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.	Clat_adaptor_s domain-containing protein.	0.983
AP3B1	SNAPIN	ENSCATP00000029618	ENSCATP00000042938	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.	SNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...]	0.624
AP3B2	AP3B1	ENSCATP00000013958	ENSCATP00000029618	AP-3 complex subunit beta.	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.	0.929
AP3B2	AP3D1	ENSCATP00000013958	ENSCATP00000019259	AP-3 complex subunit beta.	AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane.	0.994
AP3B2	AP3M1	ENSCATP00000013958	ENSCATP00000003977	AP-3 complex subunit beta.	AP-3 complex subunit mu-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes; Belongs to the adaptor complexes medium subunit family.	0.990
AP3B2	AP3M2	ENSCATP00000013958	ENSCATP00000038715	AP-3 complex subunit beta.	AP-3 complex subunit mu-2.	0.990
AP3B2	AP3S1	ENSCATP00000013958	ENSCATP00000015103	AP-3 complex subunit beta.	Adaptor related protein complex 3 subunit sigma 1.	0.982
AP3B2	DTNBP1	ENSCATP00000013958	ENSCATP00000018062	AP-3 complex subunit beta.	Dystrobrevin binding protein 1.	0.484
AP3B2	LOC105594535	ENSCATP00000013958	ENSCATP00000035719	AP-3 complex subunit beta.	Clat_adaptor_s domain-containing protein.	0.982
AP3B2	SNAPIN	ENSCATP00000013958	ENSCATP00000042938	AP-3 complex subunit beta.	SNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...]	0.624
AP3D1	AP3B1	ENSCATP00000019259	ENSCATP00000029618	AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane.	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.	0.997
AP3D1	AP3B2	ENSCATP00000019259	ENSCATP00000013958	AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane.	AP-3 complex subunit beta.	0.994