STRINGSTRING
LOC105575603 LOC105575603 TYK2 TYK2 ENSCATP00000001099 ENSCATP00000001099 ENSCATP00000001543 ENSCATP00000001543 SYK SYK SOCS1 SOCS1 STAT5B STAT5B NFKBIZ NFKBIZ PTPN6 PTPN6 LOC105584272 LOC105584272 FOXP3 FOXP3 SPTA1 SPTA1 IHH IHH SMARCD1 SMARCD1 TESPA1 TESPA1 CD70 CD70 PPP3CA PPP3CA SOX4 SOX4 ENSCATP00000003834 ENSCATP00000003834 SRC SRC ADAM8 ADAM8 RUNX3 RUNX3 PDCD1LG2 PDCD1LG2 RHOA RHOA SOCS5 SOCS5 ENSCATP00000005869 ENSCATP00000005869 IL12RB2 IL12RB2 AKT1 AKT1 KITLG KITLG RHOH RHOH TNFRSF13C TNFRSF13C PCK1 PCK1 SOX12 SOX12 JAK3 JAK3 ICOSLG ICOSLG LOC105575006 LOC105575006 EFNB2 EFNB2 HLA-DPA1 HLA-DPA1 PBRM1 PBRM1 JAK2 JAK2 PTPRC PTPRC TNFSF11 TNFSF11 ZP4 ZP4 SLC7A1 SLC7A1 ENSCATP00000009181 ENSCATP00000009181 TGFB1 TGFB1 ENSCATP00000010103 ENSCATP00000010103 DPP4 DPP4 NLRP3 NLRP3 SMARCB1 SMARCB1 IL23A IL23A ZBTB7B ZBTB7B CD55 CD55 HLA-DQB1 HLA-DQB1 LYN LYN SMARCA4 SMARCA4 ENSCATP00000012914 ENSCATP00000012914 TRAF6 TRAF6 HLA-DMA HLA-DMA NCK1 NCK1 MYB MYB HLX HLX TNFRSF14 TNFRSF14 CAV1 CAV1 EGR3 EGR3 CCDC88B CCDC88B LEP LEP LOC105575604 LOC105575604 LGALS1 LGALS1 CSK CSK RASAL3 RASAL3 SMARCD3 SMARCD3 ENSCATP00000014761 ENSCATP00000014761 CD24 CD24 CARD11 CARD11 IL21 IL21 ITPKB ITPKB FCHO1 FCHO1 THY1 THY1 HHLA2 HHLA2 TMIGD2 TMIGD2 FLOT2 FLOT2 IL2RG IL2RG SMARCA2 SMARCA2 CD6 CD6 TNFSF9 TNFSF9 ZBTB1 ZBTB1 ABL1 ABL1 TNFSF13B TNFSF13B CD83 CD83 ANXA1 ANXA1 SMARCC2 SMARCC2 IL1B IL1B CD80 CD80 ENSCATP00000018187 ENSCATP00000018187 SIRPD SIRPD SART1 SART1 PNP PNP VAV1 VAV1 RAG1 RAG1 BAD BAD IL12RB1 IL12RB1 SASH3 SASH3 VNN1 VNN1 SMARCE1 SMARCE1 BCL10 BCL10 AP3D1 AP3D1 LOC105575605 LOC105575605 LOC105576724 LOC105576724 PTPN11 PTPN11 CD86 CD86 CD5 CD5 LOC105576725 LOC105576725 GLI2 GLI2 IL2 IL2 PRKCQ PRKCQ TNFSF14 TNFSF14 IFNG IFNG LOC105600307 LOC105600307 TFRC TFRC ABL2 ABL2 LEF1 LEF1 FYN FYN CD27 CD27 IL6ST IL6ST RPS3 RPS3 HAVCR2 HAVCR2 AGER AGER IL7 IL7 ARID1A ARID1A FADD FADD MAP3K8 MAP3K8 VTCN1 VTCN1 IL7R IL7R HLA-DOA HLA-DOA IL12B IL12B CD40LG CD40LG SMARCC1 SMARCC1 PRKCZ PRKCZ CD276 CD276 GLI3 GLI3 YES1 YES1 PIK3CA PIK3CA ENSCATP00000027231 ENSCATP00000027231 VNN3 VNN3 EPHB6 EPHB6 DOCK8 DOCK8 AMBRA1 AMBRA1 TNFSF4 TNFSF4 DNAJA3 DNAJA3 LOC105576705 LOC105576705 CLECL1 CLECL1 SHB SHB ARID1B ARID1B ADA ADA CORO1A CORO1A XBP1 XBP1 BCL6 BCL6 VCAM1 VCAM1 LOC105572493 LOC105572493 AP3B1 AP3B1 IL4R IL4R HLA-DPB1 HLA-DPB1 DUSP10 DUSP10 ENSCATP00000030286 ENSCATP00000030286 ZAP70 ZAP70 KAT5 KAT5 NCK2 NCK2 SHH SHH EFNB1 EFNB1 GPAM GPAM PTPN22 PTPN22 ZBTB16 ZBTB16 PYCARD PYCARD NCKAP1L NCKAP1L CD209 CD209 CD81 CD81 IGFBP2 IGFBP2 LOC105600305 LOC105600305 IL36B IL36B TGFBR2 TGFBR2 ARID2 ARID2 MALT1 MALT1 SIRPG SIRPG ZMIZ1 ZMIZ1 ENSCATP00000034919 ENSCATP00000034919 ENSCATP00000035156 ENSCATP00000035156 RUNX1 RUNX1 EFNB3 EFNB3 LOC105583891 LOC105583891 ENSCATP00000036371 ENSCATP00000036371 CD1D CD1D IL6 IL6 SIRPB1 SIRPB1 CCR7 CCR7 IL12A IL12A IL27RA IL27RA ACTL6B ACTL6B CD74 CD74 PHF10 PHF10 ENSCATP00000038390 ENSCATP00000038390 NFKBID NFKBID VSIR VSIR IL15 IL15 MDK MDK WNT10B WNT10B CBFB CBFB IGF2 IGF2 RIPK2 RIPK2 AIF1 AIF1 IL4 IL4 SMARCD2 SMARCD2 CD28 CD28 SLAMF1 SLAMF1 IL23R IL23R FAM49B FAM49B IGF1 IGF1 CD3E CD3E LOC105575013 LOC105575013 BTN2A2 BTN2A2 ICOS ICOS HLA-E HLA-E IL18 IL18 ENSCATP00000042935 ENSCATP00000042935 CCL19 CCL19 RASGRP1 RASGRP1 IL1RL2 IL1RL2 SIRPA SIRPA CD274 CD274 LCK LCK IL4I1 IL4I1 CD160 CD160 SOX13 SOX13 RARA RARA ENSCATP00000044421 ENSCATP00000044421 HLA-DRA HLA-DRA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC105575603Ig-like domain-containing protein. (284 aa)
TYK2Tyrosine-protein kinase. (1164 aa)
ENSCATP00000001099Ig-like domain-containing protein. (272 aa)
ENSCATP00000001543Ig-like domain-containing protein. (271 aa)
SYKNon-specific protein-tyrosine kinase. (637 aa)
SOCS1Suppressor of cytokine signaling 1. (213 aa)
STAT5BSignal transducer and activator of transcription. (787 aa)
NFKBIZNFKB inhibitor zeta. (719 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (623 aa)
LOC105584272KH type-2 domain-containing protein. (164 aa)
FOXP3Forkhead box P3. (456 aa)
SPTA1Spectrin alpha, erythrocytic 1. (2420 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa)
SMARCD1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1. (515 aa)
TESPA1Thymocyte expressed, positive selection associated 1. (520 aa)
CD70TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (316 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
SOX4Transcription factor SOX. (475 aa)
ENSCATP00000003834PTN_MK_N domain-containing protein. (60 aa)
SRCTyrosine-protein kinase. (644 aa)
ADAM8ADAM metallopeptidase domain 8. (939 aa)
RUNX3Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (428 aa)
PDCD1LG2Programmed cell death 1 ligand 2. (273 aa)
RHOARas homolog family member A. (193 aa)
SOCS5Suppressor of cytokine signaling 5. (536 aa)
ENSCATP00000005869Uncharacterized protein. (526 aa)
IL12RB2Interleukin 12 receptor subunit beta 2. (847 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa)
RHOHRas homolog family member H. (191 aa)
TNFRSF13CTNF receptor superfamily member 13C. (157 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
SOX12Transcription factor SOX. (314 aa)
JAK3Tyrosine-protein kinase. (1124 aa)
ICOSLGUncharacterized protein. (302 aa)
LOC105575006Ig-like domain-containing protein. (263 aa)
EFNB2Ephrin B2; Belongs to the ephrin family. (333 aa)
HLA-DPA1Major histocompatibility complex, class II, DP alpha 1; Belongs to the MHC class II family. (260 aa)
PBRM1Polybromo 1. (1725 aa)
JAK2Tyrosine-protein kinase. (1137 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1310 aa)
TNFSF11TNF superfamily member 11; Belongs to the tumor necrosis factor family. (270 aa)
ZP4Zona pellucida glycoprotein 4. (539 aa)
SLC7A1Solute carrier family 7 member 1. (629 aa)
ENSCATP00000009181HMG box domain-containing protein. (177 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
ENSCATP00000010103Ig-like domain-containing protein. (273 aa)
DPP4Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (770 aa)
NLRP3NLR family pyrin domain containing 3. (1035 aa)
SMARCB1SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (385 aa)
IL23AInterleukin 23 subunit alpha. (189 aa)
ZBTB7BZinc finger and BTB domain containing 7B. (573 aa)
CD55Uncharacterized protein. (581 aa)
HLA-DQB1Major histocompatibility complex, class II, DQ beta 1. (284 aa)
LYNTyrosine-protein kinase. (507 aa)
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1679 aa)
ENSCATP00000012914Tyrosine-protein kinase. (399 aa)
TRAF6TNF receptor-associated factor 6; E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, IRAK1, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. Mediates activation of NF-kappa-B and JUN. May be essential for the formation of functional osteoclasts. Seems to also play a role in dendritic cells (DCs) maturation and/or activation. Represses c-Myb-mediated transactivation, in B-lymphocytes. Adapter protein that seems to [...] (522 aa)
HLA-DMAMajor histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family. (290 aa)
NCK1Cytoplasmic protein. (377 aa)
MYBMYB proto-oncogene, transcription factor. (761 aa)
HLXH2.0 like homeobox. (494 aa)
TNFRSF14TNF receptor superfamily member 14. (281 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
EGR3Early growth response 3. (387 aa)
CCDC88BCoiled-coil domain containing 88B. (1476 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
LOC105575604Ig-like domain-containing protein; Belongs to the MHC class II family. (255 aa)
LGALS1Galectin. (135 aa)
CSKTyrosine-protein kinase. (450 aa)
RASAL3RAS protein activator like 3. (1013 aa)
SMARCD3SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (575 aa)
ENSCATP00000014761Ig-like domain-containing protein. (262 aa)
CD24CD24 molecule. (126 aa)
CARD11Caspase recruitment domain family member 11. (1154 aa)
IL21Interleukin; Belongs to the IL-15/IL-21 family. (162 aa)
ITPKBKinase; Belongs to the inositol phosphokinase (IPK) family. (945 aa)
FCHO1FCH domain only 1. (882 aa)
THY1Thy-1 cell surface antigen. (161 aa)
HHLA2HERV-H LTR-associating 2. (429 aa)
TMIGD2Transmembrane and immunoglobulin domain containing 2. (302 aa)
FLOT2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (505 aa)
IL2RGFibronectin type-III domain-containing protein. (369 aa)
SMARCA2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2. (1576 aa)
CD6CD6 molecule. (682 aa)
TNFSF9TNF superfamily member 9; Belongs to the tumor necrosis factor family. (251 aa)
ZBTB1Zinc finger and BTB domain containing 1. (644 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
TNFSF13BTNF superfamily member 13b; Belongs to the tumor necrosis factor family. (285 aa)
CD83CD83 molecule. (205 aa)
ANXA1Annexin. (352 aa)
SMARCC2SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2. (1271 aa)
IL1BInterleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (268 aa)
CD80CD80 molecule. (288 aa)
ENSCATP00000018187Ig-like domain-containing protein. (265 aa)
SIRPDSignal regulatory protein delta. (198 aa)
SART1Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (800 aa)
PNPPurine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (289 aa)
VAV1Vav guanine nucleotide exchange factor 1. (856 aa)
RAG1V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1065 aa)
BADBCL2 associated agonist of cell death. (167 aa)
IL12RB1Interleukin 12 receptor subunit beta 1. (629 aa)
SASH3SAM and SH3 domain containing 3. (380 aa)
VNN1Vanin 1. (465 aa)
SMARCE1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1. (411 aa)
BCL10BCL10 immune signaling adaptor. (311 aa)
AP3D1AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane. (1213 aa)
LOC105575605Ig-like domain-containing protein. (263 aa)
LOC105576724Ig-like domain-containing protein. (283 aa)
PTPN11Protein tyrosine phosphatase non-receptor type 11. (552 aa)
CD86CD86 molecule. (329 aa)
CD5CD5 molecule. (499 aa)
LOC105576725Ig-like domain-containing protein. (283 aa)
GLI2GLI family zinc finger 2. (1586 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells; Belongs to the IL-2 family. (154 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
TNFSF14TNF superfamily member 14; Belongs to the tumor necrosis factor family. (240 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (165 aa)
LOC105600307Ig-like domain-containing protein. (268 aa)
TFRCTransferrin receptor. (755 aa)
ABL2Tyrosine-protein kinase. (1172 aa)
LEF1Lymphoid enhancer binding factor 1. (399 aa)
FYNTyrosine-protein kinase. (537 aa)
CD27CD27 molecule. (260 aa)
IL6STInterleukin 6 signal transducer. (918 aa)
RPS3Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (268 aa)
HAVCR2Hepatitis A virus cellular receptor 2. (294 aa)
AGERAdvanced glycosylation end-product specific receptor. (403 aa)
IL7Interleukin 7. (184 aa)
ARID1AAT-rich interaction domain 1A. (2286 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
MAP3K8Mitogen-activated protein kinase kinase kinase 8. (572 aa)
VTCN1V-set domain containing T cell activation inhibitor 1. (285 aa)
IL7RInterleukin 7 receptor. (459 aa)
HLA-DOAMajor histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family. (298 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Belongs to the IL-12B family. (328 aa)
CD40LGCD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] (261 aa)
SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1. (1105 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa)
CD276CD276 molecule. (534 aa)
GLI3GLI family zinc finger 3. (1580 aa)
YES1Tyrosine-protein kinase. (543 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
ENSCATP00000027231Uncharacterized protein. (159 aa)
VNN3Vanin 3. (274 aa)
EPHB6EPH receptor B6. (1017 aa)
DOCK8Dedicator of cytokinesis 8; Belongs to the DOCK family. (2098 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1298 aa)
TNFSF4TNF superfamily member 4; Belongs to the tumor necrosis factor family. (183 aa)
DNAJA3DnaJ heat shock protein family (Hsp40) member A3. (480 aa)
LOC105576705Ig-like domain-containing protein; Belongs to the MHC class I family. (368 aa)
CLECL1Uncharacterized protein. (168 aa)
SHBSH2 domain containing adaptor protein B. (509 aa)
ARID1BAT-rich interaction domain 1B. (2293 aa)
ADAA_deaminase domain-containing protein. (449 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (519 aa)
XBP1BZIP domain-containing protein. (380 aa)
BCL6BCL6 transcription repressor. (706 aa)
VCAM1Vascular cell adhesion molecule 1. (739 aa)
LOC105572493KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (242 aa)
AP3B1AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1094 aa)
IL4RInterleukin 4 receptor. (825 aa)
HLA-DPB1Major histocompatibility complex, class II, DP beta 1. (258 aa)
DUSP10Dual specificity phosphatase 10. (505 aa)
ENSCATP00000030286Uncharacterized protein. (95 aa)
ZAP70Tyrosine-protein kinase. (619 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (537 aa)
NCK2Cytoplasmic protein. (382 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (462 aa)
EFNB1Ephrin B1; Belongs to the ephrin family. (346 aa)
GPAMGlycerol-3-phosphate acyltransferase 1, mitochondrial. (815 aa)
PTPN22Protein tyrosine phosphatase non-receptor type 22. (812 aa)
ZBTB16Zinc finger and BTB domain containing 16. (673 aa)
PYCARDPYD and CARD domain containing. (195 aa)
NCKAP1LNCK associated protein 1 like. (1060 aa)
CD209CD209 molecule. (404 aa)
CD81Tetraspanin. (269 aa)
IGFBP2Insulin like growth factor binding protein 2. (325 aa)
LOC105600305Ig-like domain-containing protein; Belongs to the MHC class II family. (219 aa)
IL36BInterleukin 36 beta. (164 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
ARID2AT-rich interaction domain 2. (1836 aa)
MALT1MALT1 paracaspase. (824 aa)
SIRPGSignal regulatory protein gamma. (394 aa)
ZMIZ1Zinc finger MIZ-type containing 1. (1073 aa)
ENSCATP00000034919Ig-like domain-containing protein. (264 aa)
ENSCATP00000035156IGc1 domain-containing protein. (178 aa)
RUNX1Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa)
EFNB3Ephrin B3; Belongs to the ephrin family. (340 aa)
LOC105583891Ig-like domain-containing protein. (339 aa)
ENSCATP00000036371A_deaminase domain-containing protein. (346 aa)
CD1DCD1d molecule. (337 aa)
IL6Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (214 aa)
SIRPB1Uncharacterized protein. (397 aa)
CCR7C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (378 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (253 aa)
IL27RAInterleukin 27 receptor subunit alpha. (636 aa)
ACTL6BActin like 6B; Belongs to the actin family. (426 aa)
CD74CD74 molecule. (294 aa)
PHF10PHD finger protein 10. (410 aa)
ENSCATP00000038390Uncharacterized protein. (144 aa)
NFKBIDNFKB inhibitor delta. (505 aa)
VSIRV-set immunoregulatory receptor. (311 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (162 aa)
MDKMidkine. (143 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
CBFBCore-binding factor subunit beta. (182 aa)
IGF2Insulin like growth factor 2. (236 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa)
AIF1Allograft inflammatory factor 1. (147 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (153 aa)
SMARCD2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2. (531 aa)
CD28CD28 molecule. (234 aa)
SLAMF1Signaling lymphocytic activation molecule family member 1. (356 aa)
IL23RInterleukin 23 receptor. (614 aa)
FAM49BFamily with sequence similarity 49 member B. (324 aa)
IGF1Insulin like growth factor 1. (208 aa)
CD3ECD3e molecule. (198 aa)
LOC105575013Ig-like domain-containing protein. (273 aa)
BTN2A2Uncharacterized protein. (519 aa)
ICOSInducible T cell costimulator. (199 aa)
HLA-EMajor histocompatibility complex, class I, E; Belongs to the MHC class I family. (356 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa)
ENSCATP00000042935Ribosomal_S3_C domain-containing protein. (236 aa)
CCL19C-C motif chemokine. (123 aa)
RASGRP1RAS guanyl releasing protein 1. (837 aa)
IL1RL2Interleukin 1 receptor like 2. (575 aa)
SIRPAUncharacterized protein. (507 aa)
CD274CD274 molecule. (290 aa)
LCKTyrosine-protein kinase. (540 aa)
IL4I1Amine oxidase. (589 aa)
CD160CD160 molecule. (234 aa)
SOX13SRY-box transcription factor 13. (621 aa)
RARARetinoic acid receptor alpha. (478 aa)
ENSCATP00000044421Uncharacterized protein. (441 aa)
HLA-DRAMajor histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (254 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
Server load: low (28%) [HD]