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LOC105575603 | Ig-like domain-containing protein. (284 aa) | ||||
TYK2 | Tyrosine-protein kinase. (1164 aa) | ||||
ENSCATP00000001099 | Ig-like domain-containing protein. (272 aa) | ||||
ENSCATP00000001543 | Ig-like domain-containing protein. (271 aa) | ||||
SYK | Non-specific protein-tyrosine kinase. (637 aa) | ||||
SOCS1 | Suppressor of cytokine signaling 1. (213 aa) | ||||
STAT5B | Signal transducer and activator of transcription. (787 aa) | ||||
NFKBIZ | NFKB inhibitor zeta. (719 aa) | ||||
PTPN6 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (623 aa) | ||||
LOC105584272 | KH type-2 domain-containing protein. (164 aa) | ||||
FOXP3 | Forkhead box P3. (456 aa) | ||||
SPTA1 | Spectrin alpha, erythrocytic 1. (2420 aa) | ||||
IHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa) | ||||
SMARCD1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1. (515 aa) | ||||
TESPA1 | Thymocyte expressed, positive selection associated 1. (520 aa) | ||||
CD70 | TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (316 aa) | ||||
PPP3CA | Serine/threonine-protein phosphatase. (521 aa) | ||||
SOX4 | Transcription factor SOX. (475 aa) | ||||
ENSCATP00000003834 | PTN_MK_N domain-containing protein. (60 aa) | ||||
SRC | Tyrosine-protein kinase. (644 aa) | ||||
ADAM8 | ADAM metallopeptidase domain 8. (939 aa) | ||||
RUNX3 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (428 aa) | ||||
PDCD1LG2 | Programmed cell death 1 ligand 2. (273 aa) | ||||
RHOA | Ras homolog family member A. (193 aa) | ||||
SOCS5 | Suppressor of cytokine signaling 5. (536 aa) | ||||
ENSCATP00000005869 | Uncharacterized protein. (526 aa) | ||||
IL12RB2 | Interleukin 12 receptor subunit beta 2. (847 aa) | ||||
AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) | ||||
KITLG | Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa) | ||||
RHOH | Ras homolog family member H. (191 aa) | ||||
TNFRSF13C | TNF receptor superfamily member 13C. (157 aa) | ||||
PCK1 | Phosphoenolpyruvate carboxykinase 1. (622 aa) | ||||
SOX12 | Transcription factor SOX. (314 aa) | ||||
JAK3 | Tyrosine-protein kinase. (1124 aa) | ||||
ICOSLG | Uncharacterized protein. (302 aa) | ||||
LOC105575006 | Ig-like domain-containing protein. (263 aa) | ||||
EFNB2 | Ephrin B2; Belongs to the ephrin family. (333 aa) | ||||
HLA-DPA1 | Major histocompatibility complex, class II, DP alpha 1; Belongs to the MHC class II family. (260 aa) | ||||
PBRM1 | Polybromo 1. (1725 aa) | ||||
JAK2 | Tyrosine-protein kinase. (1137 aa) | ||||
PTPRC | Protein tyrosine phosphatase receptor type C. (1310 aa) | ||||
TNFSF11 | TNF superfamily member 11; Belongs to the tumor necrosis factor family. (270 aa) | ||||
ZP4 | Zona pellucida glycoprotein 4. (539 aa) | ||||
SLC7A1 | Solute carrier family 7 member 1. (629 aa) | ||||
ENSCATP00000009181 | HMG box domain-containing protein. (177 aa) | ||||
TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) | ||||
ENSCATP00000010103 | Ig-like domain-containing protein. (273 aa) | ||||
DPP4 | Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (770 aa) | ||||
NLRP3 | NLR family pyrin domain containing 3. (1035 aa) | ||||
SMARCB1 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (385 aa) | ||||
IL23A | Interleukin 23 subunit alpha. (189 aa) | ||||
ZBTB7B | Zinc finger and BTB domain containing 7B. (573 aa) | ||||
CD55 | Uncharacterized protein. (581 aa) | ||||
HLA-DQB1 | Major histocompatibility complex, class II, DQ beta 1. (284 aa) | ||||
LYN | Tyrosine-protein kinase. (507 aa) | ||||
SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1679 aa) | ||||
ENSCATP00000012914 | Tyrosine-protein kinase. (399 aa) | ||||
TRAF6 | TNF receptor-associated factor 6; E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, IRAK1, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. Mediates activation of NF-kappa-B and JUN. May be essential for the formation of functional osteoclasts. Seems to also play a role in dendritic cells (DCs) maturation and/or activation. Represses c-Myb-mediated transactivation, in B-lymphocytes. Adapter protein that seems to [...] (522 aa) | ||||
HLA-DMA | Major histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family. (290 aa) | ||||
NCK1 | Cytoplasmic protein. (377 aa) | ||||
MYB | MYB proto-oncogene, transcription factor. (761 aa) | ||||
HLX | H2.0 like homeobox. (494 aa) | ||||
TNFRSF14 | TNF receptor superfamily member 14. (281 aa) | ||||
CAV1 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa) | ||||
EGR3 | Early growth response 3. (387 aa) | ||||
CCDC88B | Coiled-coil domain containing 88B. (1476 aa) | ||||
LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa) | ||||
LOC105575604 | Ig-like domain-containing protein; Belongs to the MHC class II family. (255 aa) | ||||
LGALS1 | Galectin. (135 aa) | ||||
CSK | Tyrosine-protein kinase. (450 aa) | ||||
RASAL3 | RAS protein activator like 3. (1013 aa) | ||||
SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (575 aa) | ||||
ENSCATP00000014761 | Ig-like domain-containing protein. (262 aa) | ||||
CD24 | CD24 molecule. (126 aa) | ||||
CARD11 | Caspase recruitment domain family member 11. (1154 aa) | ||||
IL21 | Interleukin; Belongs to the IL-15/IL-21 family. (162 aa) | ||||
ITPKB | Kinase; Belongs to the inositol phosphokinase (IPK) family. (945 aa) | ||||
FCHO1 | FCH domain only 1. (882 aa) | ||||
THY1 | Thy-1 cell surface antigen. (161 aa) | ||||
HHLA2 | HERV-H LTR-associating 2. (429 aa) | ||||
TMIGD2 | Transmembrane and immunoglobulin domain containing 2. (302 aa) | ||||
FLOT2 | Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (505 aa) | ||||
IL2RG | Fibronectin type-III domain-containing protein. (369 aa) | ||||
SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2. (1576 aa) | ||||
CD6 | CD6 molecule. (682 aa) | ||||
TNFSF9 | TNF superfamily member 9; Belongs to the tumor necrosis factor family. (251 aa) | ||||
ZBTB1 | Zinc finger and BTB domain containing 1. (644 aa) | ||||
ABL1 | Tyrosine-protein kinase. (1149 aa) | ||||
TNFSF13B | TNF superfamily member 13b; Belongs to the tumor necrosis factor family. (285 aa) | ||||
CD83 | CD83 molecule. (205 aa) | ||||
ANXA1 | Annexin. (352 aa) | ||||
SMARCC2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2. (1271 aa) | ||||
IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (268 aa) | ||||
CD80 | CD80 molecule. (288 aa) | ||||
ENSCATP00000018187 | Ig-like domain-containing protein. (265 aa) | ||||
SIRPD | Signal regulatory protein delta. (198 aa) | ||||
SART1 | Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (800 aa) | ||||
PNP | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (289 aa) | ||||
VAV1 | Vav guanine nucleotide exchange factor 1. (856 aa) | ||||
RAG1 | V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1065 aa) | ||||
BAD | BCL2 associated agonist of cell death. (167 aa) | ||||
IL12RB1 | Interleukin 12 receptor subunit beta 1. (629 aa) | ||||
SASH3 | SAM and SH3 domain containing 3. (380 aa) | ||||
VNN1 | Vanin 1. (465 aa) | ||||
SMARCE1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1. (411 aa) | ||||
BCL10 | BCL10 immune signaling adaptor. (311 aa) | ||||
AP3D1 | AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane. (1213 aa) | ||||
LOC105575605 | Ig-like domain-containing protein. (263 aa) | ||||
LOC105576724 | Ig-like domain-containing protein. (283 aa) | ||||
PTPN11 | Protein tyrosine phosphatase non-receptor type 11. (552 aa) | ||||
CD86 | CD86 molecule. (329 aa) | ||||
CD5 | CD5 molecule. (499 aa) | ||||
LOC105576725 | Ig-like domain-containing protein. (283 aa) | ||||
GLI2 | GLI family zinc finger 2. (1586 aa) | ||||
IL2 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells; Belongs to the IL-2 family. (154 aa) | ||||
PRKCQ | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa) | ||||
TNFSF14 | TNF superfamily member 14; Belongs to the tumor necrosis factor family. (240 aa) | ||||
IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (165 aa) | ||||
LOC105600307 | Ig-like domain-containing protein. (268 aa) | ||||
TFRC | Transferrin receptor. (755 aa) | ||||
ABL2 | Tyrosine-protein kinase. (1172 aa) | ||||
LEF1 | Lymphoid enhancer binding factor 1. (399 aa) | ||||
FYN | Tyrosine-protein kinase. (537 aa) | ||||
CD27 | CD27 molecule. (260 aa) | ||||
IL6ST | Interleukin 6 signal transducer. (918 aa) | ||||
RPS3 | Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (268 aa) | ||||
HAVCR2 | Hepatitis A virus cellular receptor 2. (294 aa) | ||||
AGER | Advanced glycosylation end-product specific receptor. (403 aa) | ||||
IL7 | Interleukin 7. (184 aa) | ||||
ARID1A | AT-rich interaction domain 1A. (2286 aa) | ||||
FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa) | ||||
MAP3K8 | Mitogen-activated protein kinase kinase kinase 8. (572 aa) | ||||
VTCN1 | V-set domain containing T cell activation inhibitor 1. (285 aa) | ||||
IL7R | Interleukin 7 receptor. (459 aa) | ||||
HLA-DOA | Major histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family. (298 aa) | ||||
IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Belongs to the IL-12B family. (328 aa) | ||||
CD40LG | CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] (261 aa) | ||||
SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1. (1105 aa) | ||||
PRKCZ | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa) | ||||
CD276 | CD276 molecule. (534 aa) | ||||
GLI3 | GLI family zinc finger 3. (1580 aa) | ||||
YES1 | Tyrosine-protein kinase. (543 aa) | ||||
PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa) | ||||
ENSCATP00000027231 | Uncharacterized protein. (159 aa) | ||||
VNN3 | Vanin 3. (274 aa) | ||||
EPHB6 | EPH receptor B6. (1017 aa) | ||||
DOCK8 | Dedicator of cytokinesis 8; Belongs to the DOCK family. (2098 aa) | ||||
AMBRA1 | Autophagy and beclin 1 regulator 1. (1298 aa) | ||||
TNFSF4 | TNF superfamily member 4; Belongs to the tumor necrosis factor family. (183 aa) | ||||
DNAJA3 | DnaJ heat shock protein family (Hsp40) member A3. (480 aa) | ||||
LOC105576705 | Ig-like domain-containing protein; Belongs to the MHC class I family. (368 aa) | ||||
CLECL1 | Uncharacterized protein. (168 aa) | ||||
SHB | SH2 domain containing adaptor protein B. (509 aa) | ||||
ARID1B | AT-rich interaction domain 1B. (2293 aa) | ||||
ADA | A_deaminase domain-containing protein. (449 aa) | ||||
CORO1A | Coronin; Belongs to the WD repeat coronin family. (519 aa) | ||||
XBP1 | BZIP domain-containing protein. (380 aa) | ||||
BCL6 | BCL6 transcription repressor. (706 aa) | ||||
VCAM1 | Vascular cell adhesion molecule 1. (739 aa) | ||||
LOC105572493 | KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (242 aa) | ||||
AP3B1 | AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1094 aa) | ||||
IL4R | Interleukin 4 receptor. (825 aa) | ||||
HLA-DPB1 | Major histocompatibility complex, class II, DP beta 1. (258 aa) | ||||
DUSP10 | Dual specificity phosphatase 10. (505 aa) | ||||
ENSCATP00000030286 | Uncharacterized protein. (95 aa) | ||||
ZAP70 | Tyrosine-protein kinase. (619 aa) | ||||
KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (537 aa) | ||||
NCK2 | Cytoplasmic protein. (382 aa) | ||||
SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (462 aa) | ||||
EFNB1 | Ephrin B1; Belongs to the ephrin family. (346 aa) | ||||
GPAM | Glycerol-3-phosphate acyltransferase 1, mitochondrial. (815 aa) | ||||
PTPN22 | Protein tyrosine phosphatase non-receptor type 22. (812 aa) | ||||
ZBTB16 | Zinc finger and BTB domain containing 16. (673 aa) | ||||
PYCARD | PYD and CARD domain containing. (195 aa) | ||||
NCKAP1L | NCK associated protein 1 like. (1060 aa) | ||||
CD209 | CD209 molecule. (404 aa) | ||||
CD81 | Tetraspanin. (269 aa) | ||||
IGFBP2 | Insulin like growth factor binding protein 2. (325 aa) | ||||
LOC105600305 | Ig-like domain-containing protein; Belongs to the MHC class II family. (219 aa) | ||||
IL36B | Interleukin 36 beta. (164 aa) | ||||
TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa) | ||||
ARID2 | AT-rich interaction domain 2. (1836 aa) | ||||
MALT1 | MALT1 paracaspase. (824 aa) | ||||
SIRPG | Signal regulatory protein gamma. (394 aa) | ||||
ZMIZ1 | Zinc finger MIZ-type containing 1. (1073 aa) | ||||
ENSCATP00000034919 | Ig-like domain-containing protein. (264 aa) | ||||
ENSCATP00000035156 | IGc1 domain-containing protein. (178 aa) | ||||
RUNX1 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa) | ||||
EFNB3 | Ephrin B3; Belongs to the ephrin family. (340 aa) | ||||
LOC105583891 | Ig-like domain-containing protein. (339 aa) | ||||
ENSCATP00000036371 | A_deaminase domain-containing protein. (346 aa) | ||||
CD1D | CD1d molecule. (337 aa) | ||||
IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (214 aa) | ||||
SIRPB1 | Uncharacterized protein. (397 aa) | ||||
CCR7 | C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (378 aa) | ||||
IL12A | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (253 aa) | ||||
IL27RA | Interleukin 27 receptor subunit alpha. (636 aa) | ||||
ACTL6B | Actin like 6B; Belongs to the actin family. (426 aa) | ||||
CD74 | CD74 molecule. (294 aa) | ||||
PHF10 | PHD finger protein 10. (410 aa) | ||||
ENSCATP00000038390 | Uncharacterized protein. (144 aa) | ||||
NFKBID | NFKB inhibitor delta. (505 aa) | ||||
VSIR | V-set immunoregulatory receptor. (311 aa) | ||||
IL15 | Interleukin; Belongs to the IL-15/IL-21 family. (162 aa) | ||||
MDK | Midkine. (143 aa) | ||||
WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa) | ||||
CBFB | Core-binding factor subunit beta. (182 aa) | ||||
IGF2 | Insulin like growth factor 2. (236 aa) | ||||
RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa) | ||||
AIF1 | Allograft inflammatory factor 1. (147 aa) | ||||
IL4 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (153 aa) | ||||
SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2. (531 aa) | ||||
CD28 | CD28 molecule. (234 aa) | ||||
SLAMF1 | Signaling lymphocytic activation molecule family member 1. (356 aa) | ||||
IL23R | Interleukin 23 receptor. (614 aa) | ||||
FAM49B | Family with sequence similarity 49 member B. (324 aa) | ||||
IGF1 | Insulin like growth factor 1. (208 aa) | ||||
CD3E | CD3e molecule. (198 aa) | ||||
LOC105575013 | Ig-like domain-containing protein. (273 aa) | ||||
BTN2A2 | Uncharacterized protein. (519 aa) | ||||
ICOS | Inducible T cell costimulator. (199 aa) | ||||
HLA-E | Major histocompatibility complex, class I, E; Belongs to the MHC class I family. (356 aa) | ||||
IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa) | ||||
ENSCATP00000042935 | Ribosomal_S3_C domain-containing protein. (236 aa) | ||||
CCL19 | C-C motif chemokine. (123 aa) | ||||
RASGRP1 | RAS guanyl releasing protein 1. (837 aa) | ||||
IL1RL2 | Interleukin 1 receptor like 2. (575 aa) | ||||
SIRPA | Uncharacterized protein. (507 aa) | ||||
CD274 | CD274 molecule. (290 aa) | ||||
LCK | Tyrosine-protein kinase. (540 aa) | ||||
IL4I1 | Amine oxidase. (589 aa) | ||||
CD160 | CD160 molecule. (234 aa) | ||||
SOX13 | SRY-box transcription factor 13. (621 aa) | ||||
RARA | Retinoic acid receptor alpha. (478 aa) | ||||
ENSCATP00000044421 | Uncharacterized protein. (441 aa) | ||||
HLA-DRA | Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (254 aa) |