31 items (Cercocebus atys) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HPSE	Heparanase. (539 aa)
	AFDN	Afadin, adherens junction formation factor. (1834 aa)
	MARVELD2	MARVEL domain containing 2. (559 aa)
	CLDN3	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa)
	RAPGEF1	Rap guanine nucleotide exchange factor 1. (1303 aa)
	PECAM1	Platelet and endothelial cell adhesion molecule 1. (721 aa)
	PDE4D	Phosphodiesterase. (809 aa)
	RAP2C	RAP2C, member of RAS oncogene family. (183 aa)
	RAPGEF3	Rap guanine nucleotide exchange factor 3. (925 aa)
	EDNRB	Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (507 aa)
	F11R	F11 receptor. (259 aa)
	EZR	Ezrin. (603 aa)
	PPP1R16B	Protein phosphatase 1 regulatory subunit 16B. (568 aa)
	MYADM	Myeloid associated differentiation marker. (325 aa)
	MSN	Moesin. (577 aa)
	TJP1	Tight junction protein 1; Belongs to the MAGUK family. (1742 aa)
	SOX18	SRY-box transcription factor 18. (376 aa)
	CLDN1	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
	FASN	Fatty acid synthase. (2511 aa)
	ENSCATP00000026377	Uncharacterized protein. (170 aa)
	TJP3	Tight junction protein 3; Belongs to the MAGUK family. (917 aa)
	RDX	FERM domain-containing protein. (604 aa)
	RAPGEF2	Rap guanine nucleotide exchange factor 2. (1591 aa)
	EDNRA	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
	PDE2A	Phosphodiesterase. (942 aa)
	ENSCATP00000040503	FERM domain-containing protein. (476 aa)
	PTPRS	Protein tyrosine phosphatase receptor type S. (1948 aa)
	MYD88	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes (By similarity). MyD88-mediated signaling in intestinal epithelial cells is cruc [...] (309 aa)
	ROBO4	Roundabout guidance receptor 4. (1007 aa)
	RAP1B	Uncharacterized protein. (184 aa)
	RAP1A	RAP1A, member of RAS oncogene family. (184 aa)

Your Current Organism:

Cercocebus atys

NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFDN	ENSCATP00000026377	ENSCATP00000002568	ENSCATP00000026377	Afadin, adherens junction formation factor.	Uncharacterized protein.	0.901
AFDN	F11R	ENSCATP00000002568	ENSCATP00000012814	Afadin, adherens junction formation factor.	F11 receptor.	0.954
AFDN	RAP1A	ENSCATP00000002568	ENSCATP00000044905	Afadin, adherens junction formation factor.	RAP1A, member of RAS oncogene family.	0.940
AFDN	RAP1B	ENSCATP00000002568	ENSCATP00000044290	Afadin, adherens junction formation factor.	Uncharacterized protein.	0.901
AFDN	RAP2C	ENSCATP00000002568	ENSCATP00000011424	Afadin, adherens junction formation factor.	RAP2C, member of RAS oncogene family.	0.580
AFDN	RAPGEF2	ENSCATP00000002568	ENSCATP00000038330	Afadin, adherens junction formation factor.	Rap guanine nucleotide exchange factor 2.	0.455
AFDN	TJP1	ENSCATP00000002568	ENSCATP00000023448	Afadin, adherens junction formation factor.	Tight junction protein 1; Belongs to the MAGUK family.	0.966
AFDN	TJP3	ENSCATP00000002568	ENSCATP00000030514	Afadin, adherens junction formation factor.	Tight junction protein 3; Belongs to the MAGUK family.	0.825
CLDN1	CLDN3	ENSCATP00000025662	ENSCATP00000006452	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.871
CLDN1	F11R	ENSCATP00000025662	ENSCATP00000012814	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	F11 receptor.	0.554
CLDN1	MARVELD2	ENSCATP00000025662	ENSCATP00000003168	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	MARVEL domain containing 2.	0.480
CLDN1	TJP1	ENSCATP00000025662	ENSCATP00000023448	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Tight junction protein 1; Belongs to the MAGUK family.	0.954
CLDN1	TJP3	ENSCATP00000025662	ENSCATP00000030514	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Tight junction protein 3; Belongs to the MAGUK family.	0.941
CLDN3	CLDN1	ENSCATP00000006452	ENSCATP00000025662	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.871
CLDN3	MARVELD2	ENSCATP00000006452	ENSCATP00000003168	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	MARVEL domain containing 2.	0.482
CLDN3	TJP1	ENSCATP00000006452	ENSCATP00000023448	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Tight junction protein 1; Belongs to the MAGUK family.	0.965
CLDN3	TJP3	ENSCATP00000006452	ENSCATP00000030514	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Tight junction protein 3; Belongs to the MAGUK family.	0.897
EDNRA	EDNRB	ENSCATP00000038523	ENSCATP00000011466	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family.	0.938
EDNRB	EDNRA	ENSCATP00000011466	ENSCATP00000038523	Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	0.938
ENSCATP00000026377	AFDN	ENSCATP00000026377	ENSCATP00000002568	Uncharacterized protein.	Afadin, adherens junction formation factor.	0.901