12 items (Cercocebus atys) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

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textmining

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protein homology

Your Input:
	POT1	Protection of telomeres 1. (634 aa)
	TINF2	TERF1 interacting nuclear factor 2. (439 aa)
	PINX1	PIN2 (TERF1) interacting telomerase inhibitor 1. (322 aa)
	ZNF827	Zinc finger protein 827. (1349 aa)
	XRCC5	X-ray repair cross complementing 5. (799 aa)
	TERF2	Telomeric repeat binding factor 2. (542 aa)
	TNKS	Poly [ADP-ribose] polymerase. (1327 aa)
	TERT	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1123 aa)
	TNKS2	Poly [ADP-ribose] polymerase. (1315 aa)
	ATR	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2573 aa)
	BRCA2	BRCA2 DNA repair associated. (3419 aa)
	NABP2	Nucleic acid binding protein 2. (211 aa)

Your Current Organism:

Cercocebus atys

NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATR	BRCA2	ENSCATP00000021242	ENSCATP00000015406	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	BRCA2 DNA repair associated.	0.532
ATR	TERT	ENSCATP00000021242	ENSCATP00000026361	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...]	0.512
ATR	XRCC5	ENSCATP00000021242	ENSCATP00000036422	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	X-ray repair cross complementing 5.	0.577
BRCA2	ATR	ENSCATP00000015406	ENSCATP00000021242	BRCA2 DNA repair associated.	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	0.532
BRCA2	XRCC5	ENSCATP00000015406	ENSCATP00000036422	BRCA2 DNA repair associated.	X-ray repair cross complementing 5.	0.656
PINX1	TERT	ENSCATP00000042141	ENSCATP00000026361	PIN2 (TERF1) interacting telomerase inhibitor 1.	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...]	0.621
POT1	TERF2	ENSCATP00000011062	ENSCATP00000031136	Protection of telomeres 1.	Telomeric repeat binding factor 2.	0.984
POT1	TERT	ENSCATP00000011062	ENSCATP00000026361	Protection of telomeres 1.	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...]	0.958
POT1	TINF2	ENSCATP00000011062	ENSCATP00000043038	Protection of telomeres 1.	TERF1 interacting nuclear factor 2.	0.994
POT1	TNKS	ENSCATP00000011062	ENSCATP00000028465	Protection of telomeres 1.	Poly [ADP-ribose] polymerase.	0.429
TERF2	POT1	ENSCATP00000031136	ENSCATP00000011062	Telomeric repeat binding factor 2.	Protection of telomeres 1.	0.984
TERF2	TERT	ENSCATP00000031136	ENSCATP00000026361	Telomeric repeat binding factor 2.	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...]	0.569
TERF2	TINF2	ENSCATP00000031136	ENSCATP00000043038	Telomeric repeat binding factor 2.	TERF1 interacting nuclear factor 2.	0.987
TERF2	TNKS	ENSCATP00000031136	ENSCATP00000028465	Telomeric repeat binding factor 2.	Poly [ADP-ribose] polymerase.	0.503
TERT	ATR	ENSCATP00000026361	ENSCATP00000021242	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...]	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	0.512
TERT	PINX1	ENSCATP00000026361	ENSCATP00000042141	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...]	PIN2 (TERF1) interacting telomerase inhibitor 1.	0.621
TERT	POT1	ENSCATP00000026361	ENSCATP00000011062	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...]	Protection of telomeres 1.	0.958
TERT	TERF2	ENSCATP00000026361	ENSCATP00000031136	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...]	Telomeric repeat binding factor 2.	0.569
TERT	TINF2	ENSCATP00000026361	ENSCATP00000043038	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...]	TERF1 interacting nuclear factor 2.	0.738
TERT	XRCC5	ENSCATP00000026361	ENSCATP00000036422	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...]	X-ray repair cross complementing 5.	0.915