(18 nodes) Proteasome binding network (Cercocebus atys)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	USP14	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (486 aa)
	RAD23A	RAD23 homolog A, nucleotide excision repair protein. (363 aa)
	WFS1	Wolframin ER transmembrane glycoprotein. (891 aa)
	UBD	Ubiquitin D. (165 aa)
	ID1	Inhibitor of DNA binding 1, HLH protein. (154 aa)
	USP13	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (863 aa)
	UCHL5	Ubiquitin carboxyl-terminal hydrolase. (368 aa)
	BAG6	BCL2 associated athanogene 6. (1126 aa)
	RAD23B	RAD23 homolog B, nucleotide excision repair protein. (409 aa)
	SACS	Sacsin molecular chaperone. (4568 aa)
	LOC105578309	Ubiquitin-like domain-containing protein. (342 aa)
	PSMG1	Proteasome assembly chaperone 1; Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with psmg2. (288 aa)
	PSMD14	Proteasome 26S subunit, non-ATPase 14. (315 aa)
	ADRM1	Adhesion regulating molecule 1. (407 aa)
	PSME4	Proteasome activator subunit 4. (1792 aa)
	DNAJB2	DnaJ heat shock protein family (Hsp40) member B2. (277 aa)
	PSMF1	Proteasome inhibitor subunit 1. (271 aa)
	ZFAND1	Zinc finger AN1-type containing 1. (268 aa)

Your Current Organism:

Cercocebus atys

NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADRM1	LOC105578309	ENSCATP00000039981	ENSCATP00000034739	Adhesion regulating molecule 1.	Ubiquitin-like domain-containing protein.	0.709
ADRM1	PSMD14	ENSCATP00000039981	ENSCATP00000039810	Adhesion regulating molecule 1.	Proteasome 26S subunit, non-ATPase 14.	0.968
ADRM1	PSME4	ENSCATP00000039981	ENSCATP00000045188	Adhesion regulating molecule 1.	Proteasome activator subunit 4.	0.893
ADRM1	PSMF1	ENSCATP00000039981	ENSCATP00000004933	Adhesion regulating molecule 1.	Proteasome inhibitor subunit 1.	0.704
ADRM1	RAD23A	ENSCATP00000039981	ENSCATP00000000965	Adhesion regulating molecule 1.	RAD23 homolog A, nucleotide excision repair protein.	0.709
ADRM1	RAD23B	ENSCATP00000039981	ENSCATP00000026554	Adhesion regulating molecule 1.	RAD23 homolog B, nucleotide excision repair protein.	0.709
ADRM1	UBD	ENSCATP00000039981	ENSCATP00000008115	Adhesion regulating molecule 1.	Ubiquitin D.	0.732
ADRM1	UCHL5	ENSCATP00000039981	ENSCATP00000023566	Adhesion regulating molecule 1.	Ubiquitin carboxyl-terminal hydrolase.	0.993
ADRM1	USP14	ENSCATP00000039981	ENSCATP00000003819	Adhesion regulating molecule 1.	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.	0.951
BAG6	PSMD14	ENSCATP00000024762	ENSCATP00000039810	BCL2 associated athanogene 6.	Proteasome 26S subunit, non-ATPase 14.	0.604
BAG6	UBD	ENSCATP00000024762	ENSCATP00000008115	BCL2 associated athanogene 6.	Ubiquitin D.	0.513
LOC105578309	ADRM1	ENSCATP00000034739	ENSCATP00000039981	Ubiquitin-like domain-containing protein.	Adhesion regulating molecule 1.	0.709
LOC105578309	PSMD14	ENSCATP00000034739	ENSCATP00000039810	Ubiquitin-like domain-containing protein.	Proteasome 26S subunit, non-ATPase 14.	0.875
LOC105578309	RAD23A	ENSCATP00000034739	ENSCATP00000000965	Ubiquitin-like domain-containing protein.	RAD23 homolog A, nucleotide excision repair protein.	0.657
LOC105578309	UBD	ENSCATP00000034739	ENSCATP00000008115	Ubiquitin-like domain-containing protein.	Ubiquitin D.	0.679
LOC105578309	UCHL5	ENSCATP00000034739	ENSCATP00000023566	Ubiquitin-like domain-containing protein.	Ubiquitin carboxyl-terminal hydrolase.	0.452
LOC105578309	USP13	ENSCATP00000034739	ENSCATP00000018208	Ubiquitin-like domain-containing protein.	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.	0.581
LOC105578309	USP14	ENSCATP00000034739	ENSCATP00000003819	Ubiquitin-like domain-containing protein.	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.	0.620
PSMD14	ADRM1	ENSCATP00000039810	ENSCATP00000039981	Proteasome 26S subunit, non-ATPase 14.	Adhesion regulating molecule 1.	0.968
PSMD14	BAG6	ENSCATP00000039810	ENSCATP00000024762	Proteasome 26S subunit, non-ATPase 14.	BCL2 associated athanogene 6.	0.604