59 items (Cercocebus atys) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC105600607	Uncharacterized protein. (267 aa)
	INHBB	Inhibin subunit beta B. (407 aa)
	ZFP36L1	ZFP36 ring finger protein like 1. (338 aa)
	ENSCATP00000041705	Uncharacterized protein. (296 aa)
	PKD2	Polycystin 2, transient receptor potential cation channel. (969 aa)
	IGFBP5	Insulin like growth factor binding protein 5. (272 aa)
	HCN1	Hyperpolarization activated cyclic nucleotide gated potassium channel 1. (885 aa)
	RAP1A	RAP1A, member of RAS oncogene family. (184 aa)
	CFTR	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1481 aa)
	RAP1B	Uncharacterized protein. (184 aa)
	AQP9	Aquaporin 9; Belongs to the MIP/aquaporin (TC 1.A.8) family. (295 aa)
	HCN4	Hyperpolarization activated cyclic nucleotide gated potassium channel 4. (1204 aa)
	ENSCATP00000031597	RL10P_insert domain-containing protein. (279 aa)
	SLC26A6	Solute carrier family 26 member 6. (759 aa)
	PIK3CG	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa)
	DMTN	Dematin actin binding protein. (406 aa)
	RAPGEF2	Rap guanine nucleotide exchange factor 2. (1591 aa)
	ADIPOQ	Adiponectin, C1Q and collagen domain containing. (274 aa)
	ENSCATP00000038880	RL10P_insert domain-containing protein. (171 aa)
	PDE2A	Phosphodiesterase. (942 aa)
	HCN2	Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2. (833 aa)
	WNT10B	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
	INPP5K	Inositol polyphosphate-5-phosphatase K. (448 aa)
	SLC26A3	Chloride anion exchanger; Chloride/bicarbonate exchanger. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (703 aa)
	SLC8A1	Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (973 aa)
	ITPR2	Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
	AKAP6	A-kinase anchoring protein 6. (2318 aa)
	KCNQ1	Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (676 aa)
	ENSCATP00000026831	Uncharacterized protein. (339 aa)
	ENSCATP00000026377	Uncharacterized protein. (170 aa)
	ENSCATP00000023477	Uncharacterized protein. (452 aa)
	KDM1A	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (876 aa)
	ENSCATP00000022589	RL10P_insert domain-containing protein. (275 aa)
	WT1	WT1 transcription factor. (518 aa)
	AANAT	Aralkylamine N-acetyltransferase. (246 aa)
	HCN3	Hyperpolarization activated cyclic nucleotide gated potassium channel 3. (777 aa)
	LOC105592159	proenkephalin-A. (267 aa)
	ENSCATP00000019334	Uncharacterized protein. (425 aa)
	CPS1	Carbamoyl-phosphate synthase 1. (1507 aa)
	RPLP0	Ribosomal protein lateral stalk subunit P0. (339 aa)
	CRHBP	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (322 aa)
	EEF2K	Eukaryotic elongation factor 2 kinase. (725 aa)
	EZR	Ezrin. (603 aa)
	FDX1	Ferredoxin 1. (172 aa)
	RAPGEF3	Rap guanine nucleotide exchange factor 3. (925 aa)
	PDE4D	Phosphodiesterase. (809 aa)
	AKAP7	A-kinase anchoring protein 7. (348 aa)
	AKAP9	A-kinase anchoring protein 9. (3802 aa)
	AQP8	Aquaporin 8; Belongs to the MIP/aquaporin (TC 1.A.8) family. (261 aa)
	STC1	Stanniocalcin 1. (247 aa)
	RAPGEF1	Rap guanine nucleotide exchange factor 1. (1303 aa)
	GATA1	GATA binding protein 1. (413 aa)
	GPD1	Glycerol-3-phosphate dehydrogenase [NAD(+)]. (349 aa)
	ENSCATP00000007363	Uncharacterized protein. (150 aa)
	ENSCATP00000004982	60S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10. (303 aa)
	AQP1	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (296 aa)
	CYP1B1	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (547 aa)
	ASS1	Uncharacterized protein. (412 aa)
	ENSCATP00000002723	RL10P_insert domain-containing protein. (234 aa)

Your Current Organism:

Cercocebus atys

NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AANAT	KDM1A	ENSCATP00000022398	ENSCATP00000023336	Aralkylamine N-acetyltransferase.	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	0.472
AKAP6	AKAP7	ENSCATP00000027726	ENSCATP00000010900	A-kinase anchoring protein 6.	A-kinase anchoring protein 7.	0.564
AKAP6	PDE4D	ENSCATP00000027726	ENSCATP00000010994	A-kinase anchoring protein 6.	Phosphodiesterase.	0.511
AKAP6	RAPGEF3	ENSCATP00000027726	ENSCATP00000011459	A-kinase anchoring protein 6.	Rap guanine nucleotide exchange factor 3.	0.563
AKAP7	AKAP6	ENSCATP00000010900	ENSCATP00000027726	A-kinase anchoring protein 7.	A-kinase anchoring protein 6.	0.564
AKAP7	PDE4D	ENSCATP00000010900	ENSCATP00000010994	A-kinase anchoring protein 7.	Phosphodiesterase.	0.482
AKAP9	KCNQ1	ENSCATP00000010642	ENSCATP00000027233	A-kinase anchoring protein 9.	Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family.	0.856
AQP1	AQP8	ENSCATP00000004617	ENSCATP00000009249	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Aquaporin 8; Belongs to the MIP/aquaporin (TC 1.A.8) family.	0.670
AQP1	AQP9	ENSCATP00000004617	ENSCATP00000042852	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Aquaporin 9; Belongs to the MIP/aquaporin (TC 1.A.8) family.	0.668
AQP8	AQP1	ENSCATP00000009249	ENSCATP00000004617	Aquaporin 8; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	0.670
AQP8	AQP9	ENSCATP00000009249	ENSCATP00000042852	Aquaporin 8; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Aquaporin 9; Belongs to the MIP/aquaporin (TC 1.A.8) family.	0.636
AQP9	AQP1	ENSCATP00000042852	ENSCATP00000004617	Aquaporin 9; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	0.668
AQP9	AQP8	ENSCATP00000042852	ENSCATP00000009249	Aquaporin 9; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Aquaporin 8; Belongs to the MIP/aquaporin (TC 1.A.8) family.	0.636
ASS1	CPS1	ENSCATP00000003412	ENSCATP00000019026	Uncharacterized protein.	Carbamoyl-phosphate synthase 1.	0.950
ASS1	ENSCATP00000023477	ENSCATP00000003412	ENSCATP00000023477	Uncharacterized protein.	Uncharacterized protein.	0.797
CFTR	EZR	ENSCATP00000045859	ENSCATP00000013065	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.	Ezrin.	0.442
CFTR	RAPGEF3	ENSCATP00000045859	ENSCATP00000011459	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.	Rap guanine nucleotide exchange factor 3.	0.438
CFTR	SLC26A3	ENSCATP00000045859	ENSCATP00000040525	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.	Chloride anion exchanger; Chloride/bicarbonate exchanger. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.	0.508
CFTR	SLC26A6	ENSCATP00000045859	ENSCATP00000032718	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.	Solute carrier family 26 member 6.	0.510
CPS1	ASS1	ENSCATP00000019026	ENSCATP00000003412	Carbamoyl-phosphate synthase 1.	Uncharacterized protein.	0.950