STRINGSTRING
OSR2 OSR2 ENSCATP00000044320 ENSCATP00000044320 CD34 CD34 YTHDF2 YTHDF2 SFRP2 SFRP2 TIAL1 TIAL1 WNT10B WNT10B ELL3 ELL3 SART3 SART3 CD109 CD109 XRCC5 XRCC5 NR2E1 NR2E1 HOXB4 HOXB4 RUNX1 RUNX1 NF1 NF1 RARB RARB TRIM71 TRIM71 SFN SFN SIX2 SIX2 WNT2B WNT2B OVOL1 OVOL1 KDF1 KDF1 HMX2 HMX2 LIG4 LIG4 KDR KDR TGFB1 TGFB1 SNAI2 SNAI2 CDKN2C CDKN2C FGF9 FGF9 CEP120 CEP120 CTC1 CTC1 WNT1 WNT1 PRRX1 PRRX1 WNT3 WNT3 PBX1 PBX1 ENSCATP00000015198 ENSCATP00000015198 BRCA2 BRCA2 ENSCATP00000015497 ENSCATP00000015497 BABAM1 BABAM1 ENSCATP00000016207 ENSCATP00000016207 WNT5A WNT5A FGF8 FGF8 NES NES PTCH1 PTCH1 IFT20 IFT20 AXIN2 AXIN2 SCRG1 SCRG1 RNF43 RNF43 CTNNB1 CTNNB1 FGF4 FGF4 HOXA3 HOXA3 YAP1 YAP1 NFIB NFIB WNT11 WNT11 TP63 TP63 IRF6 IRF6 BYSL BYSL ID4 ID4 TP53 TP53 RARG RARG FGF10 FGF10 SHH SHH MECOM MECOM IRS2 IRS2 YJEFN3 YJEFN3 TBX3 TBX3 SHB SHB ETV6 ETV6 RUNX2 RUNX2 GLI3 GLI3 SHOX2 SHOX2 WNT7B WNT7B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
OSR2Odd-skipped related transciption factor 2. (401 aa)
ENSCATP00000044320HELICc2 domain-containing protein. (288 aa)
CD34CD34 molecule. (385 aa)
YTHDF2YTH N6-methyladenosine RNA binding protein 2. (583 aa)
SFRP2Secreted frizzled related protein 2. (295 aa)
TIAL1TIA1 cytotoxic granule associated RNA binding protein like 1. (392 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
ELL3Elongation factor for RNA polymerase II 3. (377 aa)
SART3Spliceosome associated factor 3, U4/U6 recycling protein. (981 aa)
CD109CD109 molecule. (1446 aa)
XRCC5X-ray repair cross complementing 5. (799 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (421 aa)
HOXB4Homeobox B4. (251 aa)
RUNX1Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa)
NF1Neurofibromin 1. (2839 aa)
RARBRetinoic acid receptor beta. (448 aa)
TRIM71Tripartite motif containing 71. (868 aa)
SFNStratifin; Belongs to the 14-3-3 family. (248 aa)
SIX2SIX homeobox 2. (290 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa)
OVOL1Ovo like transcriptional repressor 1. (267 aa)
KDF1Keratinocyte differentiation factor 1. (398 aa)
HMX2H6 family homeobox 2. (273 aa)
LIG4DNA ligase. (911 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
SNAI2Snail family transcriptional repressor 2. (268 aa)
CDKN2CCyclin dependent kinase inhibitor 2C. (168 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
CEP120Centrosomal protein 120. (1026 aa)
CTC1CST telomere replication complex component 1. (1217 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
PRRX1Paired related homeobox 1. (245 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
PBX1PBX homeobox 1. (430 aa)
ENSCATP00000015198Helicase ATP-binding domain-containing protein. (405 aa)
BRCA2BRCA2 DNA repair associated. (3419 aa)
ENSCATP00000015497RBR-type E3 ubiquitin transferase. (429 aa)
BABAM1BRISC and BRCA1 A complex member 1. (329 aa)
ENSCATP00000016207IBR domain-containing protein. (406 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (382 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
NESNestin; Belongs to the intermediate filament family. (1721 aa)
PTCH1Patched 1. (1452 aa)
IFT20Intraflagellar transport 20. (158 aa)
AXIN2Axin 2. (843 aa)
SCRG1Stimulator of chondrogenesis 1. (98 aa)
RNF43RING-type domain-containing protein. (783 aa)
CTNNB1Catenin beta 1. (781 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
HOXA3Homeobox A3. (443 aa)
YAP1Yes associated protein 1. (508 aa)
NFIBNuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (570 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (681 aa)
IRF6Interferon regulatory factor 6. (467 aa)
BYSLBystin like. (437 aa)
ID4Inhibitor of DNA binding 4, HLH protein. (161 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (402 aa)
RARGRetinoic acid receptor gamma. (463 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (462 aa)
MECOMMDS1 and EVI1 complex locus. (1230 aa)
IRS2Insulin receptor substrate 2. (1338 aa)
YJEFN3YjeF N-terminal domain containing 3. (291 aa)
TBX3T-box transcription factor 3. (743 aa)
SHBSH2 domain containing adaptor protein B. (509 aa)
ETV6ETS variant 6. (452 aa)
RUNX2RUNX family transcription factor 2. (635 aa)
GLI3GLI family zinc finger 3. (1580 aa)
SHOX2Short stature homeobox 2. (355 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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