9 items (Cercocebus atys) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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protein homology

Your Input:
	XRCC3	DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (381 aa)
	WRN	WRN RecQ like helicase. (1418 aa)
	TERF1	Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (437 aa)
	POT1	Protection of telomeres 1. (634 aa)
	RECQL4	RecQ like helicase 4. (1208 aa)
	TERF2	Telomeric repeat binding factor 2. (542 aa)
	BLM	BLM RecQ like helicase. (1416 aa)
	SLX1A	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products. (304 aa)
	SLX4	SLX4 structure-specific endonuclease subunit. (1813 aa)

Your Current Organism:

Cercocebus atys

NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BLM	POT1	ENSCATP00000035511	ENSCATP00000011062	BLM RecQ like helicase.	Protection of telomeres 1.	0.660
BLM	SLX1A	ENSCATP00000035511	ENSCATP00000036115	BLM RecQ like helicase.	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products.	0.937
BLM	SLX4	ENSCATP00000035511	ENSCATP00000043699	BLM RecQ like helicase.	SLX4 structure-specific endonuclease subunit.	0.707
BLM	TERF1	ENSCATP00000035511	ENSCATP00000008219	BLM RecQ like helicase.	Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.	0.592
BLM	TERF2	ENSCATP00000035511	ENSCATP00000031136	BLM RecQ like helicase.	Telomeric repeat binding factor 2.	0.599
BLM	WRN	ENSCATP00000035511	ENSCATP00000035398	BLM RecQ like helicase.	WRN RecQ like helicase.	0.684
BLM	XRCC3	ENSCATP00000035511	ENSCATP00000041441	BLM RecQ like helicase.	DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily.	0.956
POT1	BLM	ENSCATP00000011062	ENSCATP00000035511	Protection of telomeres 1.	BLM RecQ like helicase.	0.660
POT1	RECQL4	ENSCATP00000011062	ENSCATP00000013215	Protection of telomeres 1.	RecQ like helicase 4.	0.618
POT1	TERF1	ENSCATP00000011062	ENSCATP00000008219	Protection of telomeres 1.	Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.	0.980
POT1	TERF2	ENSCATP00000011062	ENSCATP00000031136	Protection of telomeres 1.	Telomeric repeat binding factor 2.	0.984
POT1	WRN	ENSCATP00000011062	ENSCATP00000035398	Protection of telomeres 1.	WRN RecQ like helicase.	0.981
RECQL4	POT1	ENSCATP00000013215	ENSCATP00000011062	RecQ like helicase 4.	Protection of telomeres 1.	0.618
RECQL4	SLX1A	ENSCATP00000013215	ENSCATP00000036115	RecQ like helicase 4.	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products.	0.915
RECQL4	SLX4	ENSCATP00000013215	ENSCATP00000043699	RecQ like helicase 4.	SLX4 structure-specific endonuclease subunit.	0.559
RECQL4	TERF1	ENSCATP00000013215	ENSCATP00000008219	RecQ like helicase 4.	Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.	0.486
RECQL4	TERF2	ENSCATP00000013215	ENSCATP00000031136	RecQ like helicase 4.	Telomeric repeat binding factor 2.	0.418
RECQL4	WRN	ENSCATP00000013215	ENSCATP00000035398	RecQ like helicase 4.	WRN RecQ like helicase.	0.593
RECQL4	XRCC3	ENSCATP00000013215	ENSCATP00000041441	RecQ like helicase 4.	DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily.	0.949
SLX1A	BLM	ENSCATP00000036115	ENSCATP00000035511	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products.	BLM RecQ like helicase.	0.937