STRINGSTRING
HTR3A HTR3A OLFM3 OLFM3 TRAF2 TRAF2 AMHR2 AMHR2 GP9 GP9 CD8A CD8A CHRND CHRND TYK2 TYK2 ACVR1C ACVR1C CACNG5 CACNG5 ITGA5 ITGA5 DLG4 DLG4 VWC2 VWC2 GRIN2B GRIN2B SYK SYK PTPN6 PTPN6 ITGAM ITGAM CHRNB2 CHRNB2 CD79A CD79A GP1BB GP1BB ENSCATP00000003774 ENSCATP00000003774 CHRNA6 CHRNA6 GRM1 GRM1 CACNG4 CACNG4 PMP22 PMP22 RNF31 RNF31 TRAF3 TRAF3 TLR1 TLR1 PGBD4 PGBD4 CHRNA7 CHRNA7 CALCR CALCR ITGA3 ITGA3 INSR INSR ERBB2 ERBB2 CACNG8 CACNG8 JAK2 JAK2 TGFB3 TGFB3 GABBR1 GABBR1 CD40 CD40 IFNLR1 IFNLR1 LIME1 LIME1 IGF1R IGF1R TGFB1 TGFB1 INSRR INSRR CACNG7 CACNG7 RAMP3 RAMP3 BMPR1B BMPR1B TFR2 TFR2 ERBB3 ERBB3 ITGA4 ITGA4 TGFBR1 TGFBR1 IL23A IL23A GABBR2 GABBR2 GRIN2A GRIN2A SDCBP SDCBP ITGAL ITGAL ITGA9 ITGA9 RAMP2 RAMP2 IRS1 IRS1 LYN LYN GRIK5 GRIK5 B2M B2M OLFM2 OLFM2 TRAF6 TRAF6 CHRNA1 CHRNA1 ITGA11 ITGA11 GRIK2 GRIK2 DLG3 DLG3 CNIH2 CNIH2 IFNL1 IFNL1 ENSCATP00000015286 ENSCATP00000015286 IL10RB IL10RB ENSCATP00000015541 ENSCATP00000015541 CHRNA2 CHRNA2 ITGB3 ITGB3 IL18R1 IL18R1 ENSCATP00000016559 ENSCATP00000016559 ITGAX ITGAX STXBP5 STXBP5 PTK2B PTK2B TSPAN32 TSPAN32 GRIA2 GRIA2 IL12RB1 IL12RB1 IKBKB IKBKB BMPR1A BMPR1A GRID2 GRID2 ACVR2A ACVR2A ABHD12 ABHD12 CACNG2 CACNG2 IL13RA1 IL13RA1 ITGA2B ITGA2B SHISA9 SHISA9 TRAT1 TRAT1 SHISA6 SHISA6 TFRC TFRC GRIK4 GRIK4 IL6ST IL6ST ITGA1 ITGA1 CALCRL CALCRL GPR156 GPR156 EPS8 EPS8 ITGA2 ITGA2 ITGB5 ITGB5 GRIA3 GRIA3 ITGA10 ITGA10 ITGA6 ITGA6 CSF2RA CSF2RA ACVR2B ACVR2B ITGAV ITGAV HTRA2 HTRA2 ITGB6 ITGB6 CHRNB4 CHRNB4 ITGAD ITGAD ZAP70 ZAP70 RAMP1 RAMP1 ACVR1B ACVR1B ITGAE ITGAE ITGB1 ITGB1 GRIN2C GRIN2C ITGA8 ITGA8 GRIA1 GRIA1 HJV HJV CHRNA10 CHRNA10 CHRNA5 CHRNA5 GRIA4 GRIA4 HTR3D HTR3D GRIN2D GRIN2D BIRC2 BIRC2 VWC2L VWC2L TF TF ITGB2 ITGB2 CPT1C CPT1C ITGB7 ITGB7 TGFBR2 TGFBR2 ITGB4 ITGB4 CSF2RB CSF2RB CHRNG CHRNG CD79B CD79B PORCN PORCN GRIN3A GRIN3A ITGB8 ITGB8 CNTFR CNTFR OSMR OSMR CHRNB1 CHRNB1 APBB1IP APBB1IP CACNG3 CACNG3 IL18RAP IL18RAP IL6 IL6 TRAF5 TRAF5 FLNA FLNA IL27RA IL27RA GP1BA GP1BA GRIN1 GRIN1 CD3G CD3G CSF2 CSF2 CNIH3 CNIH3 GRIN3B GRIN3B CHRNE CHRNE ITGA7 ITGA7 IL23R IL23R HTR3C HTR3C ABHD6 ABHD6 CD3E CD3E ACVR1 ACVR1 CHUK CHUK IL6R IL6R HTR3E HTR3E SKAP1 SKAP1 CHRNA4 CHRNA4 HTR3B HTR3B CHRNA9 CHRNA9 EMILIN1 EMILIN1 CD247 CD247 CD3D CD3D SHISA7 SHISA7 HFE HFE BMP2 BMP2 SHISA8 SHISA8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HTR3A5-hydroxytryptamine receptor 3A; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (515 aa)
OLFM3Olfactomedin 3. (478 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
AMHR2Anti-Muellerian hormone type-2 receptor; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone. (573 aa)
GP9Glycoprotein IX platelet. (177 aa)
CD8ACD8a molecule. (276 aa)
CHRNDCholinergic receptor nicotinic delta subunit. (517 aa)
TYK2Tyrosine-protein kinase. (1164 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (445 aa)
CACNG5Calcium voltage-gated channel auxiliary subunit gamma 5. (275 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1051 aa)
DLG4Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (767 aa)
VWC2Von Willebrand factor C domain containing 2. (325 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1484 aa)
SYKNon-specific protein-tyrosine kinase. (637 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (623 aa)
ITGAMIntegrin subunit alpha M; Belongs to the integrin alpha chain family. (1152 aa)
CHRNB2Cholinergic receptor nicotinic beta 2 subunit. (502 aa)
CD79ACD79a molecule. (225 aa)
GP1BBGlycoprotein Ib platelet subunit beta. (208 aa)
ENSCATP00000003774Uncharacterized protein. (291 aa)
CHRNA6Cholinergic receptor nicotinic alpha 6 subunit. (494 aa)
GRM1Glutamate metabotropic receptor 1. (1195 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (327 aa)
PMP22Peripheral myelin protein 22; Might be involved in growth regulation, and in myelinization in the peripheral nervous system; Belongs to the PMP-22/EMP/MP20 family. (160 aa)
RNF31Uncharacterized protein. (1072 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (571 aa)
TLR1Toll-like receptor. (786 aa)
PGBD4PiggyBac transposable element derived 4. (585 aa)
CHRNA7Uncharacterized protein. (521 aa)
CALCRCalcitonin receptor; Belongs to the G-protein coupled receptor 2 family. (489 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1064 aa)
INSRTyrosine-protein kinase receptor. (1339 aa)
ERBB2Receptor protein-tyrosine kinase. (1399 aa)
CACNG8Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (464 aa)
JAK2Tyrosine-protein kinase. (1137 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
GABBR1Gamma-aminobutyric acid type B receptor subunit 1. (1007 aa)
CD40CD40 molecule. (278 aa)
IFNLR1Interferon lambda receptor 1. (522 aa)
LIME1Uncharacterized protein. (292 aa)
IGF1RTyrosine-protein kinase receptor. (1366 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
INSRRTyrosine-protein kinase receptor. (1296 aa)
CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa)
RAMP3Receptor activity modifying protein 3. (151 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
TFR2Transferrin receptor 2. (798 aa)
ERBB3Erb-b2 receptor tyrosine kinase 3. (1349 aa)
ITGA4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1032 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
IL23AInterleukin 23 subunit alpha. (189 aa)
GABBR2Gamma-aminobutyric acid type B receptor subunit 2. (941 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1464 aa)
SDCBPSyndecan binding protein. (318 aa)
ITGALIntegrin subunit alpha L; Belongs to the integrin alpha chain family. (1155 aa)
ITGA9Integrin subunit alpha 9; Belongs to the integrin alpha chain family. (1030 aa)
RAMP2Receptor activity modifying protein 2. (175 aa)
IRS1Insulin receptor substrate 1. (1241 aa)
LYNTyrosine-protein kinase. (507 aa)
GRIK5Glutamate ionotropic receptor kainate type subunit 5. (980 aa)
B2MBeta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (119 aa)
OLFM2Olfactomedin 2. (478 aa)
TRAF6TNF receptor-associated factor 6; E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, IRAK1, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. Mediates activation of NF-kappa-B and JUN. May be essential for the formation of functional osteoclasts. Seems to also play a role in dendritic cells (DCs) maturation and/or activation. Represses c-Myb-mediated transactivation, in B-lymphocytes. Adapter protein that seems to [...] (522 aa)
CHRNA1Cholinergic receptor nicotinic alpha 1 subunit. (502 aa)
ITGA11Integrin subunit alpha 11; Belongs to the integrin alpha chain family. (1188 aa)
GRIK2Glutamate ionotropic receptor kainate type subunit 2. (908 aa)
DLG3Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family. (863 aa)
CNIH2Cornichon family AMPA receptor auxiliary protein 2. (160 aa)
IFNL1Interferon lambda 1. (202 aa)
ENSCATP00000015286PDZ domain-containing protein. (251 aa)
IL10RBInterleukin 10 receptor subunit beta. (325 aa)
ENSCATP00000015541Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (462 aa)
CHRNA2Cholinergic receptor nicotinic alpha 2 subunit. (529 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (788 aa)
IL18R1Interleukin 18 receptor 1. (540 aa)
ENSCATP00000016559PDZ domain-containing protein. (294 aa)
ITGAXIntegrin subunit alpha X; Belongs to the integrin alpha chain family. (1156 aa)
STXBP5Syntaxin binding protein 5. (1152 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1018 aa)
TSPAN32Tetraspanin 32; Belongs to the tetraspanin (TM4SF) family. (320 aa)
GRIA2Glutamate ionotropic receptor AMPA type subunit 2. (883 aa)
IL12RB1Interleukin 12 receptor subunit beta 1. (629 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
GRID2Glutamate ionotropic receptor delta type subunit 2. (922 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (514 aa)
ABHD12Abhydrolase domain containing 12. (398 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
IL13RA1Interleukin 13 receptor subunit alpha 1. (425 aa)
ITGA2BIntegrin subunit alpha 2b; Belongs to the integrin alpha chain family. (1090 aa)
SHISA9Shisa family member 9. (424 aa)
TRAT1T cell receptor associated transmembrane adaptor 1. (187 aa)
SHISA6Shisa family member 6. (553 aa)
TFRCTransferrin receptor. (755 aa)
GRIK4Glutamate ionotropic receptor kainate type subunit 4. (959 aa)
IL6STInterleukin 6 signal transducer. (918 aa)
ITGA1Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1172 aa)
CALCRLCalcitonin receptor like receptor; Belongs to the G-protein coupled receptor 2 family. (472 aa)
GPR156G protein-coupled receptor 156. (814 aa)
EPS8Epidermal growth factor receptor pathway substrate 8. (842 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1180 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (799 aa)
GRIA3Glutamate ionotropic receptor AMPA type subunit 3. (894 aa)
ITGA10Integrin subunit alpha 10; Belongs to the integrin alpha chain family. (1168 aa)
ITGA6Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (1130 aa)
CSF2RAColony stimulating factor 2 receptor alpha subunit. (361 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (512 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1048 aa)
HTRA2HtrA serine peptidase 2. (458 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (788 aa)
CHRNB4Cholinergic receptor nicotinic beta 4 subunit. (492 aa)
ITGADIntegrin subunit alpha D; Belongs to the integrin alpha chain family. (1161 aa)
ZAP70Tyrosine-protein kinase. (619 aa)
RAMP1Receptor activity modifying protein 1. (148 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (505 aa)
ITGAEIntegrin subunit alpha E; Belongs to the integrin alpha chain family. (1192 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (801 aa)
GRIN2CGlutamate ionotropic receptor NMDA type subunit 2C. (1242 aa)
ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1063 aa)
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (916 aa)
HJVHemojuvelin BMP co-receptor. (426 aa)
CHRNA10Cholinergic receptor nicotinic alpha 10 subunit. (450 aa)
CHRNA5Cholinergic receptor nicotinic alpha 5 subunit. (468 aa)
GRIA4Glutamate ionotropic receptor AMPA type subunit 4. (902 aa)
HTR3D5-hydroxytryptamine receptor 3D. (447 aa)
GRIN2DGlutamate ionotropic receptor NMDA type subunit 2D. (1375 aa)
BIRC2Baculoviral IAP repeat containing 2. (618 aa)
VWC2LVon Willebrand factor C domain containing 2 like. (222 aa)
TFTransferrin; Belongs to the transferrin family. (698 aa)
ITGB2Integrin beta. (870 aa)
CPT1CCarnitine palmitoyltransferase 1C; Belongs to the carnitine/choline acetyltransferase family. (796 aa)
ITGB7Integrin beta; Belongs to the integrin beta chain family. (798 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
ITGB4Integrin beta. (1823 aa)
CSF2RBColony stimulating factor 2 receptor beta common subunit. (897 aa)
CHRNGCholinergic receptor nicotinic gamma subunit. (516 aa)
CD79BCD79b molecule. (231 aa)
PORCNPorcupine O-acyltransferase; Belongs to the membrane-bound acyltransferase family. (531 aa)
GRIN3AGlutamate ionotropic receptor NMDA type subunit 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1115 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (769 aa)
CNTFRCiliary neurotrophic factor receptor. (373 aa)
OSMROncostatin M receptor. (977 aa)
CHRNB1Cholinergic receptor nicotinic beta 1 subunit. (501 aa)
APBB1IPAmyloid beta precursor protein binding family B member 1 interacting protein. (665 aa)
CACNG3Calcium voltage-gated channel auxiliary subunit gamma 3. (315 aa)
IL18RAPInterleukin 18 receptor accessory protein. (598 aa)
IL6Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (214 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (557 aa)
FLNAFilamin A. (2647 aa)
IL27RAInterleukin 27 receptor subunit alpha. (636 aa)
GP1BAGlycoprotein Ib platelet subunit alpha. (638 aa)
GRIN1Glutamate ionotropic receptor NMDA type subunit 1. (960 aa)
CD3GCD3g molecule. (181 aa)
CSF2Colony stimulating factor 2. (144 aa)
CNIH3Cornichon family AMPA receptor auxiliary protein 3. (160 aa)
GRIN3BGlutamate ionotropic receptor NMDA type subunit 3B; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1040 aa)
CHRNECholinergic receptor nicotinic epsilon subunit. (493 aa)
ITGA7Integrin subunit alpha 7; Belongs to the integrin alpha chain family. (1181 aa)
IL23RInterleukin 23 receptor. (614 aa)
HTR3C5-hydroxytryptamine receptor 3C; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (442 aa)
ABHD6Abhydrolase domain containing 6. (337 aa)
CD3ECD3e molecule. (198 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
IL6RInterleukin 6 receptor. (452 aa)
HTR3E5-hydroxytryptamine receptor 3E; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (409 aa)
SKAP1Src kinase associated phosphoprotein 1. (359 aa)
CHRNA4Cholinergic receptor nicotinic alpha 4 subunit. (626 aa)
HTR3B5-hydroxytryptamine receptor 3B; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (441 aa)
CHRNA9Cholinergic receptor nicotinic alpha 9 subunit. (479 aa)
EMILIN1Elastin microfibril interfacer 1. (1016 aa)
CD247CD247 molecule. (165 aa)
CD3DCD3d molecule. (171 aa)
SHISA7Shisa family member 7. (538 aa)
HFEHomeostatic iron regulator; Belongs to the MHC class I family. (348 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
SHISA8Shisa family member 8. (398 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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