STRINGSTRING
CCL26 CCL26 LPAR1 LPAR1 CDC42EP5 CDC42EP5 PLEKHH2 PLEKHH2 C15orf62 C15orf62 FAM49A FAM49A CDC42EP2 CDC42EP2 CXCL12 CXCL12 VILL VILL GSN GSN SMAD3 SMAD3 TENM1 TENM1 ARF6 ARF6 ARHGEF10 ARHGEF10 SPTA1 SPTA1 TESK1 TESK1 ENSCATP00000003424 ENSCATP00000003424 ARHGAP28 ARHGAP28 PFN3 PFN3 ENSCATP00000003612 ENSCATP00000003612 PLEKHG2 PLEKHG2 LMOD3 LMOD3 PFN2 PFN2 ARHGAP18 ARHGAP18 LOC105574672 LOC105574672 ENSCATP00000004468 ENSCATP00000004468 GMFG GMFG RASA1 RASA1 ENSCATP00000005099 ENSCATP00000005099 DLG1 DLG1 GPR65 GPR65 LATS1 LATS1 RHOA RHOA TACSTD2 TACSTD2 WASHC1 WASHC1 CDC42EP3 CDC42EP3 FMN1 FMN1 ENSCATP00000006802 ENSCATP00000006802 ADD1 ADD1 CAPZA3 CAPZA3 SHANK3 SHANK3 BAG4 BAG4 C9orf72 C9orf72 LOC105596948 LOC105596948 NCKAP1 NCKAP1 SPTBN5 SPTBN5 LOC105596959 LOC105596959 SYNPO2 SYNPO2 ENSCATP00000008237 ENSCATP00000008237 TGFB3 TGFB3 ARHGAP35 ARHGAP35 LOC105574300 LOC105574300 MAGEL2 MAGEL2 WASF2 WASF2 PFN1 PFN1 RHPN2 RHPN2 TMOD3 TMOD3 KIRREL1 KIRREL1 WNT4 WNT4 TRIOBP TRIOBP ENSCATP00000009637 ENSCATP00000009637 AP1AR AP1AR WASF1 WASF1 GMFB GMFB TGFBR1 TGFBR1 DBNL DBNL RAPGEF3 RAPGEF3 ABITRAM ABITRAM MLST8 MLST8 IQANK1 IQANK1 F11R F11R WHAMM WHAMM NCK1 NCK1 HIP1R HIP1R ARAP1 ARAP1 ENSCATP00000013592 ENSCATP00000013592 CARMIL2 CARMIL2 SERPINF1 SERPINF1 ASAP3 ASAP3 ELN ELN BRK1 BRK1 WDR1 WDR1 ID1 ID1 ARHGEF15 ARHGEF15 CARMIL3 CARMIL3 MTPN MTPN MYADM MYADM MKKS MKKS CCDC88A CCDC88A SSH2 SSH2 GBA2 GBA2 PFN4 PFN4 PAK1 PAK1 CAPZB CAPZB TMOD4 TMOD4 ARFGEF1 ARFGEF1 BBS4 BBS4 SFRP1 SFRP1 WASHC3 WASHC3 LMOD2 LMOD2 ABL1 ABL1 TSC1 TSC1 CAPZA1 CAPZA1 LOC105571637 LOC105571637 ARPC2 ARPC2 TWF1 TWF1 DLC1 DLC1 TTC8 TTC8 PTK2B PTK2B WDR63 WDR63 SNX9 SNX9 PRKN PRKN NPHS1 NPHS1 BAIAP2L1 BAIAP2L1 MYOC MYOC CTNNA2 CTNNA2 SCIN SCIN SLC9A1 SLC9A1 ENSCATP00000019774 ENSCATP00000019774 ENSCATP00000019933 ENSCATP00000019933 COTL1 COTL1 PPM1F PPM1F PICK1 PICK1 SERPINF2 SERPINF2 ARHGAP40 ARHGAP40 ARF1 ARF1 FERMT2 FERMT2 ENSCATP00000021227 ENSCATP00000021227 BRAF BRAF ARPC1A ARPC1A CRACD CRACD LIMK1 LIMK1 CSF3 CSF3 PRKCD PRKCD ARFIP2 ARFIP2 TMSB15A TMSB15A TJP1 TJP1 TACR1 TACR1 LIMCH1 LIMCH1 ARPC4 ARPC4 PIK3R2 PIK3R2 SYNPO SYNPO CAPG CAPG BIN1 BIN1 CCN2 CCN2 EPHA1 EPHA1 ARHGEF5 ARHGEF5 RHPN1 RHPN1 AMOT AMOT WNT11 WNT11 SSH1 SSH1 PDXP PDXP ITGB1BP1 ITGB1BP1 VIL1 VIL1 CGNL1 CGNL1 FHOD1 FHOD1 EPS8 EPS8 SHROOM2 SHROOM2 KANK4 KANK4 SHANK1 SHANK1 ENSCATP00000026691 ENSCATP00000026691 ARFIP1 ARFIP1 ENSCATP00000026922 ENSCATP00000026922 PIK3CA PIK3CA EVL EVL HAX1 HAX1 PAK3 PAK3 ARPC1B ARPC1B PIK3R1 PIK3R1 ENSCATP00000027915 ENSCATP00000027915 ARPC5L ARPC5L SPTBN2 SPTBN2 CYFIP2 CYFIP2 SORBS3 SORBS3 WASF3 WASF3 CORO1A CORO1A PLEK PLEK PPM1E PPM1E MTSS1 MTSS1 LOC105575288 LOC105575288 LOC105592392 LOC105592392 ARPC5 ARPC5 ENSCATP00000029599 ENSCATP00000029599 ALOX15 ALOX15 CTTN CTTN S100A10 S100A10 ABI2 ABI2 SPTAN1 SPTAN1 ENSCATP00000030673 ENSCATP00000030673 NCK2 NCK2 TMOD2 TMOD2 TRIM27 TRIM27 WASHC4 WASHC4 LIMA1 LIMA1 NAA80 NAA80 CORO1B CORO1B FHOD3 FHOD3 LMOD1 LMOD1 SDC4 SDC4 PYCARD PYCARD PAK2 PAK2 SSH3 SSH3 NCKAP1L NCKAP1L WASL WASL CLASP1 CLASP1 ACTN2 ACTN2 NRP1 NRP1 TMSB10 TMSB10 ARPC3 ARPC3 CAPZA2 CAPZA2 ENSCATP00000034499 ENSCATP00000034499 ENSCATP00000034747 ENSCATP00000034747 CYFIP1 CYFIP1 SPTBN4 SPTBN4 SWAP70 SWAP70 MTOR MTOR ENSCATP00000035938 ENSCATP00000035938 PRKCE PRKCE CORO2B CORO2B DAAM2 DAAM2 ENSCATP00000036494 ENSCATP00000036494 CCL24 CCL24 HCLS1 HCLS1 CCR7 CCR7 DMTN DMTN FLNA FLNA FER FER SYNPO2L SYNPO2L BAIAP2L2 BAIAP2L2 ARHGAP6 ARHGAP6 BAIAP2 BAIAP2 KANK1 KANK1 PHLDB2 PHLDB2 FLII FLII SEMA5A SEMA5A TWF2 TWF2 DSTN DSTN CX3CL1 CX3CL1 CCL21 CCL21 INPP5K INPP5K ENSCATP00000040503 ENSCATP00000040503 VASP VASP ALMS1 ALMS1 DEF6 DEF6 RICTOR RICTOR MET MET AVIL AVIL ENSCATP00000041372 ENSCATP00000041372 TMOD1 TMOD1 FAM49B FAM49B S1PR1 S1PR1 LOC105576025 LOC105576025 ROCK2 ROCK2 CDC42EP1 CDC42EP1 FRMD7 FRMD7 ENSCATP00000042587 ENSCATP00000042587 GRB2 GRB2 PTGER4 PTGER4 SLIT2 SLIT2 TMEFF2 TMEFF2 KANK3 KANK3 ENSCATP00000043705 ENSCATP00000043705 FCHSD1 FCHSD1 SPTBN1 SPTBN1 NF2 NF2 PXN PXN ADD2 ADD2 WAS WAS ADD3 ADD3 SPTB SPTB FCHSD2 FCHSD2 RHOC RHOC CARMIL1 CARMIL1 DBN1 DBN1 RGCC RGCC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CCL26C-C motif chemokine. (94 aa)
LPAR1Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (364 aa)
CDC42EP5CDC42 effector protein 5. (148 aa)
PLEKHH2Pleckstrin homology, MyTH4 and FERM domain containing H2. (1493 aa)
C15orf62Chromosome 15 open reading frame 62. (175 aa)
FAM49AFamily with sequence similarity 49 member A. (323 aa)
CDC42EP2Cdc42 effector protein 2; Probably involved in the organization of the actin cytoskeleton; Belongs to the BORG/CEP family. (210 aa)
CXCL12C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (140 aa)
VILLVillin like. (855 aa)
GSNGelsolin. (809 aa)
SMAD3Mothers against decapentaplegic homolog. (429 aa)
TENM1Teneurin transmembrane protein 1. (2732 aa)
ARF6ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
ARHGEF10Rho guanine nucleotide exchange factor 10. (1345 aa)
SPTA1Spectrin alpha, erythrocytic 1. (2420 aa)
TESK1Testis associated actin remodelling kinase 1. (626 aa)
ENSCATP00000003424HCLS1-associated protein X-1; Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools. (279 aa)
ARHGAP28Rho GTPase activating protein 28. (729 aa)
PFN3Profilin; Belongs to the profilin family. (137 aa)
ENSCATP00000003612Uncharacterized protein. (380 aa)
PLEKHG2Pleckstrin homology and RhoGEF domain containing G2. (1388 aa)
LMOD3Leiomodin 3. (559 aa)
PFN2Profilin; Belongs to the profilin family. (191 aa)
ARHGAP18Rho GTPase activating protein 18. (663 aa)
LOC105574672S100 calcium binding protein A10; Belongs to the S-100 family. (97 aa)
ENSCATP00000004468ADF-H domain-containing protein. (153 aa)
GMFGGlia maturation factor; Belongs to the actin-binding proteins ADF family. GMF subfamily. (142 aa)
RASA1RAS p21 protein activator 1. (1051 aa)
ENSCATP00000005099Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (161 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (925 aa)
GPR65G protein-coupled receptor 65; Belongs to the G-protein coupled receptor 1 family. (337 aa)
LATS1Large tumor suppressor kinase 1. (1179 aa)
RHOARas homolog family member A. (193 aa)
TACSTD2Tumor associated calcium signal transducer 2. (323 aa)
WASHC1WASH complex subunit 1. (473 aa)
CDC42EP3CDC42 effector protein 3. (254 aa)
FMN1Formin 1. (1425 aa)
ENSCATP00000006802Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (162 aa)
ADD1Adducin 1. (768 aa)
CAPZA3F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (299 aa)
SHANK3SH3 and multiple ankyrin repeat domains 3. (1739 aa)
BAG4BCL2 associated athanogene 4. (457 aa)
C9orf72C9orf72-SMCR8 complex subunit. (481 aa)
LOC105596948Supervillin. (2177 aa)
NCKAP1NCK associated protein 1. (1134 aa)
SPTBN5Spectrin beta, non-erythrocytic 5. (3725 aa)
LOC105596959HP domain-containing protein. (81 aa)
SYNPO2Synaptopodin 2. (1261 aa)
ENSCATP00000008237Glia maturation factor; Belongs to the actin-binding proteins ADF family. GMF subfamily. (132 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
ARHGAP35Rho GTPase activating protein 35. (1499 aa)
LOC105574300Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. (45 aa)
MAGEL2MAGE family member L2. (1250 aa)
WASF2WASP family member 2. (498 aa)
PFN1Profilin; Belongs to the profilin family. (167 aa)
RHPN2Rhophilin Rho GTPase binding protein 2. (616 aa)
TMOD3Tropomodulin 3. (352 aa)
KIRREL1Kirre like nephrin family adhesion molecule 1. (757 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (374 aa)
TRIOBPTRIO and F-actin binding protein. (2270 aa)
ENSCATP00000009637Uncharacterized protein. (61 aa)
AP1ARAdaptor related protein complex 1 associated regulatory protein. (302 aa)
WASF1WASP family member 1. (559 aa)
GMFBGlia maturation factor; Belongs to the actin-binding proteins ADF family. GMF subfamily. (150 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
DBNLDrebrin like. (440 aa)
RAPGEF3Rap guanine nucleotide exchange factor 3. (925 aa)
ABITRAMActin binding transcription modulator. (180 aa)
MLST8MTOR associated protein, LST8 homolog. (335 aa)
IQANK1IQ motif and ankyrin repeat containing 1. (564 aa)
F11RF11 receptor. (259 aa)
WHAMMWASP homolog associated with actin, golgi membranes and microtubules. (808 aa)
NCK1Cytoplasmic protein. (377 aa)
HIP1RHuntingtin interacting protein 1 related. (1068 aa)
ARAP1ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1. (1453 aa)
ENSCATP00000013592Non-specific serine/threonine protein kinase. (480 aa)
CARMIL2Capping protein regulator and myosin 1 linker 2. (1435 aa)
SERPINF1Serpin family F member 1; Belongs to the serpin family. (396 aa)
ASAP3ArfGAP with SH3 domain, ankyrin repeat and PH domain 3. (903 aa)
ELNElastin. (667 aa)
BRK1BRICK1 subunit of SCAR/WAVE actin nucleating complex. (75 aa)
WDR1WD repeat domain 1. (609 aa)
ID1Inhibitor of DNA binding 1, HLH protein. (154 aa)
ARHGEF15Rho guanine nucleotide exchange factor 15. (841 aa)
CARMIL3Capping protein regulator and myosin 1 linker 3. (1372 aa)
MTPNMyotrophin. (118 aa)
MYADMMyeloid associated differentiation marker. (325 aa)
MKKSMcKusick-Kaufman syndrome. (570 aa)
CCDC88ACoiled-coil domain containing 88A. (1843 aa)
SSH2Slingshot protein phosphatase 2. (1450 aa)
GBA2Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide. (927 aa)
PFN4Profilin; Belongs to the profilin family. (129 aa)
PAK1Non-specific serine/threonine protein kinase. (545 aa)
CAPZBF-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (301 aa)
TMOD4Tropomodulin 4. (345 aa)
ARFGEF1ADP ribosylation factor guanine nucleotide exchange factor 1. (1852 aa)
BBS4Bardet-Biedl syndrome 4. (347 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
WASHC3WASH complex subunit 3. (194 aa)
LMOD2Leiomodin 2. (552 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
TSC1TSC complex subunit 1. (1167 aa)
CAPZA1F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (286 aa)
LOC105571637Thymosin beta-15A. (45 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (306 aa)
TWF1Twinfilin actin binding protein 1. (391 aa)
DLC1Uncharacterized protein. (498 aa)
TTC8Tetratricopeptide repeat domain 8. (531 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1018 aa)
WDR63WD repeat domain 63. (888 aa)
SNX9Sorting nexin. (596 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa)
NPHS1NPHS1 adhesion molecule, nephrin. (1226 aa)
BAIAP2L1BAI1 associated protein 2 like 1. (511 aa)
MYOCMyocilin. (491 aa)
CTNNA2Catenin alpha 2. (953 aa)
SCINScinderin. (706 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa)
ENSCATP00000019774Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (139 aa)
ENSCATP00000019933ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (141 aa)
COTL1Coactosin like F-actin binding protein 1. (142 aa)
PPM1FProtein phosphatase, Mg2+/Mn2+ dependent 1F. (386 aa)
PICK1Protein interacting with PRKCA 1. (449 aa)
SERPINF2Serpin family F member 2; Belongs to the serpin family. (491 aa)
ARHGAP40Rho GTPase activating protein 40. (567 aa)
ARF1Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (181 aa)
FERMT2Fermitin family member 2. (698 aa)
ENSCATP00000021227Uncharacterized protein. (212 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (762 aa)
ARPC1AActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (370 aa)
CRACDKIAA1211. (1226 aa)
LIMK1LIM domain kinase 1. (672 aa)
CSF3Colony stimulating factor 3. (204 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
ARFIP2ADP ribosylation factor interacting protein 2. (341 aa)
TMSB15AThymosin beta 15a. (45 aa)
TJP1Tight junction protein 1; Belongs to the MAGUK family. (1742 aa)
TACR1Tachykinin receptor 1; Belongs to the G-protein coupled receptor 1 family. (407 aa)
LIMCH1LIM and calponin homology domains 1. (1467 aa)
ARPC4Actin related protein 2/3 complex subunit 4. (290 aa)
PIK3R2Uncharacterized protein. (624 aa)
SYNPOSynaptopodin. (929 aa)
CAPGCapping actin protein, gelsolin like. (348 aa)
BIN1Bridging integrator 1. (608 aa)
CCN2Cellular communication network factor 2. (349 aa)
EPHA1EPH receptor A1. (976 aa)
ARHGEF5Rho guanine nucleotide exchange factor 5. (1597 aa)
RHPN1Rhophilin Rho GTPase binding protein 1. (670 aa)
AMOTAngiomotin. (1098 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
SSH1Slingshot protein phosphatase 1. (1122 aa)
PDXPPyridoxal phosphatase; Belongs to the HAD-like hydrolase superfamily. (300 aa)
ITGB1BP1Integrin subunit beta 1 binding protein 1. (200 aa)
VIL1Villin 1. (830 aa)
CGNL1Cingulin like 1. (1303 aa)
FHOD1Formin homology 2 domain containing 1. (1182 aa)
EPS8Epidermal growth factor receptor pathway substrate 8. (842 aa)
SHROOM2Shroom family member 2. (1610 aa)
KANK4KN motif and ankyrin repeat domains 4. (993 aa)
SHANK1SH3 and multiple ankyrin repeat domains 1. (2170 aa)
ENSCATP00000026691ADF-H domain-containing protein. (126 aa)
ARFIP1ADP ribosylation factor interacting protein 1. (373 aa)
ENSCATP00000026922Uncharacterized protein. (85 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
EVLEnah/Vasp-like; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (418 aa)
HAX1HCLS1-associated protein X-1; Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools. (279 aa)
PAK3P21 (RAC1) activated kinase 3. (580 aa)
ARPC1BActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (372 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
ENSCATP00000027915Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (143 aa)
ARPC5LActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (159 aa)
SPTBN2Spectrin beta chain; Belongs to the spectrin family. (2390 aa)
CYFIP2Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1278 aa)
SORBS3Sorbin and SH3 domain containing 3. (671 aa)
WASF3WASP family member 3. (502 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (519 aa)
PLEKPleckstrin. (350 aa)
PPM1EProtein phosphatase, Mg2+/Mn2+ dependent 1E. (761 aa)
MTSS1MTSS I-BAR domain containing 1. (799 aa)
LOC105575288Uncharacterized protein. (1383 aa)
LOC105592392Clat_adaptor_s domain-containing protein. (394 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (151 aa)
ENSCATP00000029599WD_REPEATS_REGION domain-containing protein. (334 aa)
ALOX15Lipoxygenase domain-containing protein. (325 aa)
CTTNCortactin. (550 aa)
S100A10S100 calcium binding protein A10. (97 aa)
ABI2Abl interactor 2. (513 aa)
SPTAN1Spectrin alpha, non-erythrocytic 1. (2498 aa)
ENSCATP00000030673Uncharacterized protein. (652 aa)
NCK2Cytoplasmic protein. (382 aa)
TMOD2Tropomodulin 2. (341 aa)
TRIM27Tripartite motif containing 27. (513 aa)
WASHC4WASH complex subunit 4. (1173 aa)
LIMA1LIM domain and actin binding 1. (761 aa)
NAA80N(alpha)-acetyltransferase 80, NatH catalytic subunit. (308 aa)
CORO1BCoronin; Belongs to the WD repeat coronin family. (489 aa)
FHOD3Formin homology 2 domain containing 3. (1622 aa)
LMOD1Leiomodin 1. (600 aa)
SDC4Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (198 aa)
PYCARDPYD and CARD domain containing. (195 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
SSH3Slingshot protein phosphatase 3. (657 aa)
NCKAP1LNCK associated protein 1 like. (1060 aa)
WASLWASP like actin nucleation promoting factor. (503 aa)
CLASP1Cytoplasmic linker associated protein 1. (1533 aa)
ACTN2Actinin alpha 2. (894 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (926 aa)
TMSB10Thymosin beta; Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Belongs to the thymosin beta family. (44 aa)
ARPC3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (182 aa)
CAPZA2F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (268 aa)
ENSCATP00000034499Uncharacterized protein. (159 aa)
ENSCATP00000034747Uncharacterized protein. (1170 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1239 aa)
SPTBN4Spectrin beta, non-erythrocytic 4. (2565 aa)
SWAP70Switching B cell complex subunit SWAP70. (585 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
ENSCATP00000035938Uncharacterized protein. (60 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (736 aa)
CORO2BCoronin 2B. (485 aa)
DAAM2Dishevelled associated activator of morphogenesis 2. (1077 aa)
ENSCATP00000036494F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (238 aa)
CCL24C-C motif chemokine ligand 24. (119 aa)
HCLS1Hematopoietic cell-specific Lyn substrate 1. (476 aa)
CCR7C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (378 aa)
DMTNDematin actin binding protein. (406 aa)
FLNAFilamin A. (2647 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
SYNPO2LSynaptopodin 2 like. (979 aa)
BAIAP2L2BAI1 associated protein 2 like 2. (529 aa)
ARHGAP6Rho GTPase activating protein 6. (977 aa)
BAIAP2BAI1 associated protein 2. (561 aa)
KANK1KN motif and ankyrin repeat domains 1. (1352 aa)
PHLDB2Pleckstrin homology like domain family B member 2. (1355 aa)
FLIIFLII actin remodeling protein. (1269 aa)
SEMA5ASemaphorin 5A. (1074 aa)
TWF2Twinfilin actin binding protein 2. (336 aa)
DSTNDestrin, actin depolymerizing factor; Belongs to the actin-binding proteins ADF family. (165 aa)
CX3CL1C-X3-C motif chemokine ligand 1. (406 aa)
CCL21C-C motif chemokine ligand 21. (131 aa)
INPP5KInositol polyphosphate-5-phosphatase K. (448 aa)
ENSCATP00000040503FERM domain-containing protein. (476 aa)
VASPVasodilator stimulated phosphoprotein. (431 aa)
ALMS1ALMS1 centrosome and basal body associated protein. (4262 aa)
DEF6DEF6 guanine nucleotide exchange factor. (631 aa)
RICTORRPTOR independent companion of MTOR complex 2. (1732 aa)
METMET proto-oncogene, receptor tyrosine kinase. (1404 aa)
AVILAdvillin. (819 aa)
ENSCATP00000041372Profilin; Belongs to the profilin family. (91 aa)
TMOD1Tropomodulin 1. (365 aa)
FAM49BFamily with sequence similarity 49 member B. (324 aa)
S1PR1Sphingosine-1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (382 aa)
LOC105576025F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (267 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1388 aa)
CDC42EP1CDC42 effector protein 1. (370 aa)
FRMD7FERM domain containing 7. (714 aa)
ENSCATP00000042587Uncharacterized protein. (62 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
PTGER4Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (490 aa)
SLIT2Slit guidance ligand 2. (1542 aa)
TMEFF2Transmembrane protein with EGF like and two follistatin like domains 2. (374 aa)
KANK3KN motif and ankyrin repeat domains 3. (830 aa)
ENSCATP00000043705Uncharacterized protein. (238 aa)
FCHSD1FCH and double SH3 domains 1. (722 aa)
SPTBN1Spectrin beta chain; Belongs to the spectrin family. (2366 aa)
NF2Neurofibromin 2. (595 aa)
PXNPaxillin. (1082 aa)
ADD2Adducin 2. (726 aa)
WASWASP actin nucleation promoting factor. (503 aa)
ADD3Adducin 3. (706 aa)
SPTBSpectrin beta chain; Belongs to the spectrin family. (2326 aa)
FCHSD2FCH and double SH3 domains 2. (764 aa)
RHOCRas homolog family member C. (193 aa)
CARMIL1Capping protein regulator and myosin 1 linker 1. (1424 aa)
DBN1Drebrin 1. (696 aa)
RGCCRegulator of cell cycle. (137 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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