STRINGSTRING
RAB17 RAB17 APOD APOD PTPRJ PTPRJ LRTM2 LRTM2 SLIT1 SLIT1 MDGA1 MDGA1 RAP1A RAP1A MAP4K4 MAP4K4 STAU2 STAU2 SEMA4D SEMA4D NLGN2 NLGN2 RAP1B RAP1B ABI3 ABI3 NPTX1 NPTX1 ADNP ADNP FLOT1 FLOT1 COL16A1 COL16A1 GHSR GHSR NTRK1 NTRK1 ROCK2 ROCK2 WDPCP WDPCP ENSCATP00000041499 ENSCATP00000041499 BHLHB9 BHLHB9 BCAS3 BCAS3 LRRTM1 LRRTM1 PTPRS PTPRS SLITRK4 SLITRK4 LRRTM3 LRRTM3 LHFPL4 LHFPL4 LRRC24 LRRC24 MYO1C MYO1C APP APP CBLN1 CBLN1 PHLDB2 PHLDB2 ARHGAP6 ARHGAP6 PEAK1 PEAK1 RAPGEF2 RAPGEF2 DAPK3 DAPK3 NPHP1 NPHP1 DMTN DMTN SNAI1 SNAI1 MEF2C MEF2C LDB1 LDB1 ENSCATP00000036202 ENSCATP00000036202 CNTNAP2 CNTNAP2 HRG HRG MYCBP2 MYCBP2 SIX4 SIX4 NTRK2 NTRK2 LRRTM2 LRRTM2 VSTM5 VSTM5 EPB41L5 EPB41L5 NRP1 NRP1 MACF1 MACF1 IL1RAP IL1RAP CLASP1 CLASP1 ACVRL1 ACVRL1 OXT OXT SDC4 SDC4 EPHB3 EPHB3 SETD5 SETD5 NECTIN1 NECTIN1 S100A10 S100A10 CUX2 CUX2 LOC105575288 LOC105575288 LRFN1 LRFN1 ROBO2 ROBO2 IL17A IL17A AGT AGT CLSTN2 CLSTN2 NTNG2 NTNG2 EPHB2 EPHB2 ENSCATP00000026377 ENSCATP00000026377 EPHA3 EPHA3 CLDN1 CLDN1 CRB3 CRB3 SEMA4A SEMA4A CBLN2 CBLN2 ITGB1BP1 ITGB1BP1 IRX3 IRX3 ASIC2 ASIC2 POLDIP2 POLDIP2 LIMCH1 LIMCH1 TJP1 TJP1 LRFN5 LRFN5 MUSK MUSK LIMS1 LIMS1 SYNDIG1 SYNDIG1 COLQ COLQ FERMT2 FERMT2 EFNA5 EFNA5 RCC2 RCC2 VPS35 VPS35 PPM1F PPM1F TEK TEK WNT7A WNT7A SLC9A1 SLC9A1 GRID2 GRID2 MYOC MYOC LOC105575095 LOC105575095 THBS2 THBS2 IKBKB IKBKB DKK1 DKK1 IL1B IL1B DLC1 DLC1 HOPX HOPX LRFN3 LRFN3 TSC1 TSC1 ABL1 ABL1 DLG5 DLG5 SFRP1 SFRP1 THBS1 THBS1 BDNF BDNF WNT5A WNT5A AGRN AGRN ENSCATP00000016177 ENSCATP00000016177 EEF2K EEF2K ROCK1 ROCK1 SLK SLK THY1 THY1 TLN1 TLN1 ENSCATP00000014662 ENSCATP00000014662 NTN1 NTN1 CAV1 CAV1 PTEN PTEN DUSP22 DUSP22 F11R F11R TBX5 TBX5 EPHA2 EPHA2 ADGRB1 ADGRB1 VEGFA VEGFA GHRL GHRL NRXN1 NRXN1 WNT4 WNT4 SNAI2 SNAI2 LRFN4 LRFN4 NLGN1 NLGN1 RAPGEF1 RAPGEF1 KDR KDR CAMSAP3 CAMSAP3 CLSTN1 CLSTN1 WNT3A WNT3A PDLIM5 PDLIM5 LRRN1 LRRN1 AMIGO1 AMIGO1 SLITRK3 SLITRK3 LINGO2 LINGO2 LINGO4 LINGO4 FLRT3 FLRT3 CLDN3 CLDN3 FMN1 FMN1 AMIGO2 AMIGO2 SLITRK1 SLITRK1 CLDN5 CLDN5 NPHP4 NPHP4 IL1RAPL1 IL1RAPL1 LRRC4B LRRC4B EPHA7 EPHA7 TPBG TPBG PTK2 PTK2 SLITRK6 SLITRK6 SLITRK5 SLITRK5 FLRT2 FLRT2 PTPRA PTPRA CLDN19 CLDN19 LOC105574672 LOC105574672 VCL VCL SRC SRC SLITRK2 SLITRK2 ACE2 ACE2 AMIGO3 AMIGO3 CHRNB2 CHRNB2 PTPRD PTPRD LRRTM4 LRRTM4 ARF6 ARF6 TPBGL TPBGL SMAD3 SMAD3 EIF4G1 EIF4G1 EPHB1 EPHB1 FZD5 FZD5 GPC4 GPC4 GPBAR1 GPBAR1 IL1RAPL2 IL1RAPL2 CORO1C CORO1C SRPX2 SRPX2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RAB17RAB17, member RAS oncogene family. (212 aa)
APODApolipoprotein D. (189 aa)
PTPRJProtein tyrosine phosphatase receptor type J. (1337 aa)
LRTM2Leucine rich repeats and transmembrane domains 2. (430 aa)
SLIT1Slit guidance ligand 1. (1514 aa)
MDGA1MAM domain containing glycosylphosphatidylinositol anchor 1. (955 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
MAP4K4Mitogen-activated protein kinase kinase kinase kinase 4. (1351 aa)
STAU2Staufen double-stranded RNA binding protein 2. (617 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (862 aa)
NLGN2Neuroligin 2. (840 aa)
RAP1BUncharacterized protein. (184 aa)
ABI3ABI family member 3. (366 aa)
NPTX1Neuronal pentraxin 1. (432 aa)
ADNPActivity dependent neuroprotector homeobox. (1103 aa)
FLOT1Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (427 aa)
COL16A1Collagen type XVI alpha 1 chain. (1604 aa)
GHSRGrowth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
NTRK1Tyrosine-protein kinase receptor. (796 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1388 aa)
WDPCPWD repeat containing planar cell polarity effector. (711 aa)
ENSCATP00000041499Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (728 aa)
BHLHB9Arm_2 domain-containing protein. (547 aa)
BCAS3BCAS3 microtubule associated cell migration factor. (950 aa)
LRRTM1Leucine rich repeat transmembrane neuronal 1. (522 aa)
PTPRSProtein tyrosine phosphatase receptor type S. (1948 aa)
SLITRK4SLIT and NTRK like family member 4. (837 aa)
LRRTM3Leucine rich repeat transmembrane neuronal 3. (581 aa)
LHFPL4LHFPL tetraspan subfamily member 4. (247 aa)
LRRC24Leucine rich repeat containing 24. (514 aa)
MYO1CMyosin IC; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1034 aa)
APPAmyloid beta precursor protein. (770 aa)
CBLN1Cerebellin 1 precursor. (193 aa)
PHLDB2Pleckstrin homology like domain family B member 2. (1355 aa)
ARHGAP6Rho GTPase activating protein 6. (977 aa)
PEAK1Pseudopodium enriched atypical kinase 1. (1746 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2. (1591 aa)
DAPK3Death associated protein kinase 3. (422 aa)
NPHP1Nephrocystin 1. (693 aa)
DMTNDematin actin binding protein. (406 aa)
SNAI1Snail family transcriptional repressor 1. (264 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
LDB1LIM domain binding 1. (411 aa)
ENSCATP00000036202Arm_2 domain-containing protein. (446 aa)
CNTNAP2Contactin associated protein like 2. (1331 aa)
HRGHistidine rich glycoprotein. (521 aa)
MYCBP2MYC binding protein 2. (4751 aa)
SIX4SIX homeobox 4. (772 aa)
NTRK2Tyrosine-protein kinase receptor. (838 aa)
LRRTM2Leucine rich repeat transmembrane neuronal 2. (516 aa)
VSTM5V-set and transmembrane domain containing 5. (200 aa)
EPB41L5Erythrocyte membrane protein band 4.1 like 5. (733 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (926 aa)
MACF1Microtubule actin crosslinking factor 1. (7594 aa)
IL1RAPInterleukin 1 receptor accessory protein. (687 aa)
CLASP1Cytoplasmic linker associated protein 1. (1533 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (528 aa)
OXTOxytocin/neurophysin I prepropeptide; Belongs to the vasopressin/oxytocin family. (125 aa)
SDC4Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (198 aa)
EPHB3EPH receptor B3. (1008 aa)
SETD5SET domain containing 5. (1461 aa)
NECTIN1Nectin cell adhesion molecule 1. (519 aa)
S100A10S100 calcium binding protein A10. (97 aa)
CUX2Homeobox protein cut-like. (1486 aa)
LOC105575288Uncharacterized protein. (1383 aa)
LRFN1Leucine rich repeat and fibronectin type III domain containing 1. (767 aa)
ROBO2Roundabout guidance receptor 2. (1439 aa)
IL17AInterleukin 17A. (155 aa)
AGTAngiotensinogen; Belongs to the serpin family. (485 aa)
CLSTN2Calsyntenin 2. (955 aa)
NTNG2Netrin G2. (529 aa)
EPHB2EPH receptor B2. (1085 aa)
ENSCATP00000026377Uncharacterized protein. (170 aa)
EPHA3EPH receptor A3. (984 aa)
CLDN1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
CRB3Crumbs cell polarity complex component 3. (125 aa)
SEMA4ASemaphorin 4A; Belongs to the semaphorin family. (760 aa)
CBLN2Cerebellin 2 precursor. (224 aa)
ITGB1BP1Integrin subunit beta 1 binding protein 1. (200 aa)
IRX3Iroquois homeobox 3. (501 aa)
ASIC2Acid sensing ion channel subunit 2; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (512 aa)
POLDIP2DNA polymerase delta interacting protein 2. (408 aa)
LIMCH1LIM and calponin homology domains 1. (1467 aa)
TJP1Tight junction protein 1; Belongs to the MAGUK family. (1742 aa)
LRFN5Leucine rich repeat and fibronectin type III domain containing 5. (719 aa)
MUSKMuscle associated receptor tyrosine kinase. (881 aa)
LIMS1LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (398 aa)
SYNDIG1Synapse differentiation inducing 1. (258 aa)
COLQCollagen like tail subunit of asymmetric acetylcholinesterase. (458 aa)
FERMT2Fermitin family member 2. (698 aa)
EFNA5Ephrin A5; Belongs to the ephrin family. (228 aa)
RCC2Regulator of chromosome condensation 2. (522 aa)
VPS35Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (796 aa)
PPM1FProtein phosphatase, Mg2+/Mn2+ dependent 1F. (386 aa)
TEKTEK receptor tyrosine kinase. (1124 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa)
GRID2Glutamate ionotropic receptor delta type subunit 2. (922 aa)
MYOCMyocilin. (491 aa)
LOC105575095HOP homeobox. (73 aa)
THBS2Thrombospondin 2. (1172 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
DKK1Dickkopf WNT signaling pathway inhibitor 1. (266 aa)
IL1BInterleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (268 aa)
DLC1Uncharacterized protein. (498 aa)
HOPXHOP homeobox. (98 aa)
LRFN3Leucine rich repeat and fibronectin type III domain containing 3. (628 aa)
TSC1TSC complex subunit 1. (1167 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
DLG5Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1868 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
THBS1Thrombospondin 1. (1170 aa)
BDNFBrain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (312 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (382 aa)
AGRNAgrin. (2048 aa)
ENSCATP00000016177Uncharacterized protein. (501 aa)
EEF2KEukaryotic elongation factor 2 kinase. (725 aa)
ROCK1Rho associated coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1337 aa)
SLKSTE20 like kinase. (1236 aa)
THY1Thy-1 cell surface antigen. (161 aa)
TLN1Talin 1. (2546 aa)
ENSCATP00000014662Uncharacterized protein. (454 aa)
NTN1Netrin 1. (575 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
DUSP22Dual specificity phosphatase 22; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (184 aa)
F11RF11 receptor. (259 aa)
TBX5T-box transcription factor 5. (518 aa)
EPHA2EPH receptor A2. (1033 aa)
ADGRB1Adhesion G protein-coupled receptor B1; Belongs to the G-protein coupled receptor 2 family. (1581 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (409 aa)
GHRLGhrelin and obestatin prepropeptide. (117 aa)
NRXN1Neurexin 1. (1507 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (374 aa)
SNAI2Snail family transcriptional repressor 2. (268 aa)
LRFN4Leucine rich repeat and fibronectin type III domain containing 4. (635 aa)
NLGN1Neuroligin 1. (823 aa)
RAPGEF1Rap guanine nucleotide exchange factor 1. (1303 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
CAMSAP3Calmodulin regulated spectrin associated protein family member 3. (1276 aa)
CLSTN1Calsyntenin 1. (988 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
PDLIM5PDZ and LIM domain 5. (566 aa)
LRRN1Leucine rich repeat neuronal 1. (716 aa)
AMIGO1Adhesion molecule with Ig like domain 1. (493 aa)
SLITRK3SLIT and NTRK like family member 3. (979 aa)
LINGO2Leucine rich repeat and Ig domain containing 2. (606 aa)
LINGO4Leucine rich repeat and Ig domain containing 4. (593 aa)
FLRT3Fibronectin leucine rich transmembrane protein 3. (649 aa)
CLDN3Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa)
FMN1Formin 1. (1425 aa)
AMIGO2Adhesion molecule with Ig like domain 2. (521 aa)
SLITRK1SLIT and NTRK like family member 1. (696 aa)
CLDN5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa)
NPHP4Nephrocystin 4. (1426 aa)
IL1RAPL1Interleukin 1 receptor accessory protein like 1. (696 aa)
LRRC4BLeucine rich repeat containing 4B. (715 aa)
EPHA7EPH receptor A7. (998 aa)
TPBGTrophoblast glycoprotein. (420 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1068 aa)
SLITRK6SLIT and NTRK like family member 6. (841 aa)
SLITRK5SLIT and NTRK like family member 5. (958 aa)
FLRT2Fibronectin leucine rich transmembrane protein 2. (660 aa)
PTPRAReceptor-type tyrosine-protein phosphatase alpha. (802 aa)
CLDN19Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (224 aa)
LOC105574672S100 calcium binding protein A10; Belongs to the S-100 family. (97 aa)
VCLVinculin. (1134 aa)
SRCTyrosine-protein kinase. (644 aa)
SLITRK2SLIT and NTRK like family member 2. (845 aa)
ACE2Angiotensin-converting enzyme. (805 aa)
AMIGO3Adhesion molecule with Ig like domain 3. (504 aa)
CHRNB2Cholinergic receptor nicotinic beta 2 subunit. (502 aa)
PTPRDProtein tyrosine phosphatase receptor type D. (1749 aa)
LRRTM4Leucine rich repeat transmembrane neuronal 4. (564 aa)
ARF6ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
TPBGLTrophoblast glycoprotein like. (384 aa)
SMAD3Mothers against decapentaplegic homolog. (429 aa)
EIF4G1Eukaryotic translation initiation factor 4 gamma 1. (1604 aa)
EPHB1EPH receptor B1. (984 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
GPC4Glypican 4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (556 aa)
GPBAR1G protein-coupled bile acid receptor 1. (330 aa)
IL1RAPL2Interleukin 1 receptor accessory protein like 2. (686 aa)
CORO1CCoronin; Belongs to the WD repeat coronin family. (527 aa)
SRPX2Sushi repeat containing protein X-linked 2. (465 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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