44 items (Cercocebus atys) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ANAPC15	Anaphase promoting complex subunit 15. (190 aa)
	BIRC5	Uncharacterized protein. (147 aa)
	CCAR2	Cell cycle and apoptosis regulator 2. (923 aa)
	TELO2	Telomere maintenance 2. (808 aa)
	BRCA2	BRCA2 DNA repair associated. (3419 aa)
	RNASEH2B	Uncharacterized protein. (353 aa)
	TTI2	TELO2 interacting protein 2. (483 aa)
	CUL4A	Cullin 4A; Belongs to the cullin family. (759 aa)
	RFWD3	Ring finger and WD repeat domain 3. (774 aa)
	NDC80	NDC80 kinetochore complex component. (580 aa)
	THOC1	THO complex 1. (651 aa)
	CDK5RAP2	CDK5 regulatory subunit associated protein 2. (1924 aa)
	DUSP1	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (367 aa)
	PBK	PDZ binding kinase. (323 aa)
	PRAP1	Uncharacterized protein. (152 aa)
	BRD4	Bromodomain containing 4. (1217 aa)
	GEN1	GEN1 Holliday junction 5' flap endonuclease. (910 aa)
	DDX39B	DExD-box helicase 39B. (425 aa)
	AURKB	Aurora kinase B; Belongs to the protein kinase superfamily. (344 aa)
	CDT1	Chromatin licensing and DNA replication factor 1. (545 aa)
	FEM1B	Fem-1 homolog B. (627 aa)
	RAD51	RAD51 recombinase; Belongs to the RecA family. (309 aa)
	PCID2	PCI domain containing 2. (399 aa)
	CHEK2	Checkpoint kinase 2. (589 aa)
	USP44	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (713 aa)
	ETAA1	ETAA1 activator of ATR kinase. (898 aa)
	CRY1	Cryptochrome circadian regulator 1. (586 aa)
	ENSCATP00000027022	HORMA domain-containing protein. (162 aa)
	INCENP	Inner centromere protein. (768 aa)
	MAD1L1	Mitotic arrest deficient 1 like 1. (718 aa)
	LCMT1	Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family. (334 aa)
	TTI1	TELO2 interacting protein 1. (1089 aa)
	PROX1	Prospero homeobox 1. (737 aa)
	FBXO4	F-box protein 4. (387 aa)
	MAP3K20	Mitogen-activated protein kinase kinase kinase 20. (788 aa)
	PPP1R10	Protein phosphatase 1 regulatory subunit 10. (940 aa)
	TPR	Translocated promoter region, nuclear basket protein. (2439 aa)
	MAD2L1	HORMA domain-containing protein. (206 aa)
	DYNC1LI1	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (523 aa)
	MAD2L1BP	MAD2L1 binding protein. (306 aa)
	CCNB1	Cyclin B1; Belongs to the cyclin family. (433 aa)
	BARD1	BRCA1 associated RING domain 1. (777 aa)
	XRCC3	DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (381 aa)
	THOC5	THO complex 5. (686 aa)

Your Current Organism:

Cercocebus atys

NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANAPC15	AURKB	ENSCATP00000041904	ENSCATP00000043070	Anaphase promoting complex subunit 15.	Aurora kinase B; Belongs to the protein kinase superfamily.	0.475
ANAPC15	ENSCATP00000027022	ENSCATP00000041904	ENSCATP00000027022	Anaphase promoting complex subunit 15.	HORMA domain-containing protein.	0.801
ANAPC15	MAD2L1	ENSCATP00000041904	ENSCATP00000035663	Anaphase promoting complex subunit 15.	HORMA domain-containing protein.	0.801
AURKB	ANAPC15	ENSCATP00000043070	ENSCATP00000041904	Aurora kinase B; Belongs to the protein kinase superfamily.	Anaphase promoting complex subunit 15.	0.475
AURKB	BARD1	ENSCATP00000043070	ENSCATP00000040920	Aurora kinase B; Belongs to the protein kinase superfamily.	BRCA1 associated RING domain 1.	0.466
AURKB	BIRC5	ENSCATP00000043070	ENSCATP00000016566	Aurora kinase B; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.988
AURKB	CCNB1	ENSCATP00000043070	ENSCATP00000040244	Aurora kinase B; Belongs to the protein kinase superfamily.	Cyclin B1; Belongs to the cyclin family.	0.819
AURKB	CDT1	ENSCATP00000043070	ENSCATP00000043286	Aurora kinase B; Belongs to the protein kinase superfamily.	Chromatin licensing and DNA replication factor 1.	0.635
AURKB	ENSCATP00000027022	ENSCATP00000043070	ENSCATP00000027022	Aurora kinase B; Belongs to the protein kinase superfamily.	HORMA domain-containing protein.	0.798
AURKB	INCENP	ENSCATP00000043070	ENSCATP00000027414	Aurora kinase B; Belongs to the protein kinase superfamily.	Inner centromere protein.	0.994
AURKB	MAD2L1	ENSCATP00000043070	ENSCATP00000035663	Aurora kinase B; Belongs to the protein kinase superfamily.	HORMA domain-containing protein.	0.798
AURKB	NDC80	ENSCATP00000043070	ENSCATP00000012457	Aurora kinase B; Belongs to the protein kinase superfamily.	NDC80 kinetochore complex component.	0.896
AURKB	PBK	ENSCATP00000043070	ENSCATP00000007759	Aurora kinase B; Belongs to the protein kinase superfamily.	PDZ binding kinase.	0.799
AURKB	RAD51	ENSCATP00000043070	ENSCATP00000019738	Aurora kinase B; Belongs to the protein kinase superfamily.	RAD51 recombinase; Belongs to the RecA family.	0.514
BARD1	AURKB	ENSCATP00000040920	ENSCATP00000043070	BRCA1 associated RING domain 1.	Aurora kinase B; Belongs to the protein kinase superfamily.	0.466
BARD1	BRCA2	ENSCATP00000040920	ENSCATP00000015406	BRCA1 associated RING domain 1.	BRCA2 DNA repair associated.	0.979
BARD1	CHEK2	ENSCATP00000040920	ENSCATP00000023161	BRCA1 associated RING domain 1.	Checkpoint kinase 2.	0.904
BARD1	GEN1	ENSCATP00000040920	ENSCATP00000000478	BRCA1 associated RING domain 1.	GEN1 Holliday junction 5' flap endonuclease.	0.674
BARD1	RAD51	ENSCATP00000040920	ENSCATP00000019738	BRCA1 associated RING domain 1.	RAD51 recombinase; Belongs to the RecA family.	0.945
BARD1	TTI2	ENSCATP00000040920	ENSCATP00000014051	BRCA1 associated RING domain 1.	TELO2 interacting protein 2.	0.448