STRINGSTRING
SPRY2 SPRY2 BCCIP BCCIP LSM14A LSM14A CENPH CENPH KIFC1 KIFC1 KIF3B KIF3B DCTN1 DCTN1 PRC1 PRC1 RHOA RHOA MECP2 MECP2 ABRAXAS2 ABRAXAS2 ARHGEF10 ARHGEF10 GOLGA2 GOLGA2 NDE1 NDE1 NUF2 NUF2 NEK2 NEK2 TACC2 TACC2 FBXW11 FBXW11 SAPCD2 SAPCD2 MAP9 MAP9 NUMA1 NUMA1 PAFAH1B1 PAFAH1B1 TUBG2 TUBG2 NEK6 NEK6 SMC3 SMC3 AURKB AURKB ENSCATP00000042680 ENSCATP00000042680 MYBL2 MYBL2 AAAS AAAS SETD2 SETD2 KIF4A KIF4A SPRY1 SPRY1 PLK1 PLK1 CCNB1 CCNB1 ZCWPW2 ZCWPW2 FAM193B FAM193B DYNLT1 DYNLT1 DCTN2 DCTN2 WRAP73 WRAP73 SUN2 SUN2 MAPRE1 MAPRE1 NSFL1C NSFL1C FLNA FLNA KIF23 KIF23 AURKC AURKC MAD2L1 MAD2L1 PCNT PCNT HTT HTT GPSM1 GPSM1 ESPL1 ESPL1 ENSCATP00000034500 ENSCATP00000034500 KIF11 KIF11 DLGAP5 DLGAP5 CLASP1 CLASP1 LOC105575979 LOC105575979 PKHD1 PKHD1 LOC105573813 LOC105573813 SBDS SBDS FGF10 FGF10 DCTN6 DCTN6 SMC1A SMC1A GPSM2 GPSM2 CENPE CENPE KAT5 KAT5 EFHC1 EFHC1 LOC105575288 LOC105575288 CKAP5 CKAP5 TNKS TNKS CENPA CENPA KPNB1 KPNB1 INCENP INCENP ENSCATP00000027022 ENSCATP00000027022 ENSCATP00000026346 ENSCATP00000026346 PAX6 PAX6 UBXN2B UBXN2B WDR62 WDR62 STAG1 STAG1 TACC1 TACC1 INSC INSC MZT1 MZT1 POLDIP2 POLDIP2 CEP192 CEP192 ABRAXAS1 ABRAXAS1 CHEK2 CHEK2 TASOR TASOR INTS13 INTS13 EML1 EML1 STIL STIL NUSAP1 NUSAP1 RCC1 RCC1 SPDL1 SPDL1 TPX2 TPX2 AURKA AURKA PTPA PTPA CCDC61 CCDC61 DYNC1H1 DYNC1H1 MAP4 MAP4 BIRC5 BIRC5 ANKFN1 ANKFN1 ZNF207 ZNF207 MCPH1 MCPH1 PIBF1 PIBF1 ENSCATP00000014439 ENSCATP00000014439 ENSCATP00000014278 ENSCATP00000014278 MAP1S MAP1S PLK2 PLK2 TUBG1 TUBG1 NDC80 NDC80 LOC105579729 LOC105579729 SPC25 SPC25 KIFC2 KIFC2 EFHC2 EFHC2 ZW10 ZW10 MISP MISP ENSCATP00000010667 ENSCATP00000010667 STAG2 STAG2 TACC3 TACC3 CDK5RAP2 CDK5RAP2 ENSCATP00000009362 ENSCATP00000009362 CDC20 CDC20 CEP126 CEP126 TOGARAM2 TOGARAM2 TBCE TBCE SPICE1 SPICE1 VCP VCP RACGAP1 RACGAP1 TOGARAM1 TOGARAM1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SPRY2Sprouty RTK signaling antagonist 2. (338 aa)
BCCIPBRCA2 and CDKN1A interacting protein. (324 aa)
LSM14ALSM14A mRNA processing body assembly factor. (448 aa)
CENPHCentromere protein H. (247 aa)
KIFC1Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (849 aa)
KIF3BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (747 aa)
DCTN1CAP-Gly domain-containing protein. (1278 aa)
PRC1Protein regulator of cytokinesis 1. (620 aa)
RHOARas homolog family member A. (193 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (501 aa)
ABRAXAS2Abraxas 2, BRISC complex subunit. (404 aa)
ARHGEF10Rho guanine nucleotide exchange factor 10. (1345 aa)
GOLGA2Golgin A2. (1005 aa)
NDE1NudE neurodevelopment protein 1. (368 aa)
NUF2NUF2 component of NDC80 kinetochore complex. (450 aa)
NEK2NIMA related kinase 2. (445 aa)
TACC2Transforming acidic coiled-coil containing protein 2. (2850 aa)
FBXW11F-box and WD repeat domain containing 11. (563 aa)
SAPCD2Suppressor APC domain containing 2. (394 aa)
MAP9Microtubule associated protein 9. (647 aa)
NUMA1Nuclear mitotic apparatus protein 1. (2098 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (410 aa)
TUBG2Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. (466 aa)
NEK6NIMA related kinase 6; Belongs to the protein kinase superfamily. (347 aa)
SMC3Structural maintenance of chromosomes 3. (1007 aa)
AURKBAurora kinase B; Belongs to the protein kinase superfamily. (344 aa)
ENSCATP00000042680Uncharacterized protein. (400 aa)
MYBL2MYB proto-oncogene like 2. (700 aa)
AAASAladin WD repeat nucleoporin. (546 aa)
SETD2SET domain containing 2, histone lysine methyltransferase. (2529 aa)
KIF4AKinesin family member 4A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1234 aa)
SPRY1Sprouty RTK signaling antagonist 1. (319 aa)
PLK1Serine/threonine-protein kinase PLK. (603 aa)
CCNB1Cyclin B1; Belongs to the cyclin family. (433 aa)
ZCWPW2Zinc finger CW-type and PWWP domain containing 2. (362 aa)
FAM193BFamily with sequence similarity 193 member B. (822 aa)
DYNLT1Dynein light chain Tctex-type 1. (113 aa)
DCTN2Dynactin subunit 2. (427 aa)
WRAP73WD repeat containing, antisense to TP73. (454 aa)
SUN2Sad1 and UNC84 domain containing 2. (728 aa)
MAPRE1Microtubule associated protein RP/EB family member 1. (268 aa)
NSFL1CNSFL1 cofactor. (372 aa)
FLNAFilamin A. (2647 aa)
KIF23Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (974 aa)
AURKCAurora kinase C; Belongs to the protein kinase superfamily. (309 aa)
MAD2L1HORMA domain-containing protein. (206 aa)
PCNTPericentrin. (3251 aa)
HTTHuntingtin. (3113 aa)
GPSM1G protein signaling modulator 1. (704 aa)
ESPL1Extra spindle pole bodies like 1, separase. (2120 aa)
ENSCATP00000034500Uncharacterized protein. (464 aa)
KIF11Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1056 aa)
DLGAP5DLG associated protein 5. (851 aa)
CLASP1Cytoplasmic linker associated protein 1. (1533 aa)
LOC105575979CS domain-containing protein. (326 aa)
PKHD1PKHD1 ciliary IPT domain containing fibrocystin/polyductin. (4054 aa)
LOC105573813Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (394 aa)
SBDSSBDS ribosome maturation factor. (250 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
DCTN6Dynactin subunit 6. (192 aa)
SMC1AStructural maintenance of chromosomes protein. (1233 aa)
GPSM2G protein signaling modulator 2. (685 aa)
CENPECentromere protein E; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2701 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (537 aa)
EFHC1EF-hand domain containing 1. (641 aa)
LOC105575288Uncharacterized protein. (1383 aa)
CKAP5Cytoskeleton associated protein 5. (2032 aa)
TNKSPoly [ADP-ribose] polymerase. (1327 aa)
CENPACentromere protein A. (138 aa)
KPNB1Karyopherin subunit beta 1. (876 aa)
INCENPInner centromere protein. (768 aa)
ENSCATP00000027022HORMA domain-containing protein. (162 aa)
ENSCATP00000026346Uncharacterized protein. (164 aa)
PAX6Paired box 6. (493 aa)
UBXN2BUBX domain protein 2B. (331 aa)
WDR62WD repeat domain 62. (1523 aa)
STAG1Stromal antigen 1. (1291 aa)
TACC1Transforming acidic coiled-coil containing protein 1. (793 aa)
INSCINSC spindle orientation adaptor protein. (579 aa)
MZT1Mitotic spindle organizing protein 1. (82 aa)
POLDIP2DNA polymerase delta interacting protein 2. (408 aa)
CEP192Centrosomal protein 192. (2538 aa)
ABRAXAS1Abraxas 1, BRCA1 A complex subunit. (412 aa)
CHEK2Checkpoint kinase 2. (589 aa)
TASORTranscription activation suppressor. (1565 aa)
INTS13Integrator complex subunit 13. (706 aa)
EML1EMAP like 1. (853 aa)
STILSTIL centriolar assembly protein. (1236 aa)
NUSAP1Uncharacterized protein. (393 aa)
RCC1Regulator of chromosome condensation 1. (461 aa)
SPDL1Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. (605 aa)
TPX2TPX2 microtubule nucleation factor. (747 aa)
AURKAProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (403 aa)
PTPASerine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (358 aa)
CCDC61Coiled-coil domain containing 61. (512 aa)
DYNC1H1Dynein cytoplasmic 1 heavy chain 1. (4673 aa)
MAP4Microtubule-associated protein. (2255 aa)
BIRC5Uncharacterized protein. (147 aa)
ANKFN1Ankyrin repeat and fibronectin type III domain containing 1. (1149 aa)
ZNF207Zinc finger protein 207. (496 aa)
MCPH1Microcephalin 1. (891 aa)
PIBF1Progesterone immunomodulatory binding factor 1. (744 aa)
ENSCATP00000014439Uncharacterized protein. (106 aa)
ENSCATP00000014278Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. (419 aa)
MAP1SMicrotubule associated protein 1S. (1063 aa)
PLK2Serine/threonine-protein kinase PLK. (685 aa)
TUBG1Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. (451 aa)
NDC80NDC80 kinetochore complex component. (580 aa)
LOC105579729Nuclear distribution C, dynein complex regulator. (287 aa)
SPC25SPC25 component of NDC80 kinetochore complex. (235 aa)
KIFC2Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (819 aa)
EFHC2EF-hand domain containing 2. (749 aa)
ZW10Zw10 kinetochore protein. (778 aa)
MISPMitotic spindle positioning. (679 aa)
ENSCATP00000010667Uncharacterized protein. (119 aa)
STAG2Stromal antigen 2. (1268 aa)
TACC3Transforming acidic coiled-coil containing protein 3. (817 aa)
CDK5RAP2CDK5 regulatory subunit associated protein 2. (1924 aa)
ENSCATP00000009362BRCA2 and CDKN1A-interacting protein; May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ); Belongs to the BCP1 family. (293 aa)
CDC20Cell division cycle 20. (499 aa)
CEP126Centrosomal protein 126. (1116 aa)
TOGARAM2TOG array regulator of axonemal microtubules 2. (1015 aa)
TBCEUncharacterized protein. (555 aa)
SPICE1Uncharacterized protein. (856 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (806 aa)
RACGAP1Rac GTPase activating protein 1. (632 aa)
TOGARAM1TOG array regulator of axonemal microtubules 1. (1775 aa)
Your Current Organism:
Cercocebus atys
NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey
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