20 items (Cercocebus atys) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GHSR	Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
	NRARP	NOTCH regulated ankyrin repeat protein. (114 aa)
	ENSCATP00000003834	PTN_MK_N domain-containing protein. (60 aa)
	DBH	Dopamine beta-hydroxylase. (620 aa)
	SP1	Sp1 transcription factor. (786 aa)
	ITGA4	Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1032 aa)
	GHRL	Ghrelin and obestatin prepropeptide. (117 aa)
	ENSCATP00000016044	Protein kinase domain-containing protein. (357 aa)
	STAT3	Signal transducer and activator of transcription. (777 aa)
	PDPK1	3-phosphoinositide dependent protein kinase 1. (534 aa)
	AKT3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	FLT1	Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1338 aa)
	PLCG1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa)
	COL4A3	Collagen type IV alpha 3 chain. (1670 aa)
	ADAM17	ADAM metallopeptidase domain 17. (824 aa)
	SIRT6	Sirtuin 6. (355 aa)
	MEF2C	Myocyte enhancer factor 2C. (483 aa)
	MDK	Midkine. (143 aa)
	IGF2	Insulin like growth factor 2. (236 aa)
	FGFR1	Fibroblast growth factor receptor. (820 aa)

Your Current Organism:

Cercocebus atys

NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT3	PDPK1	ENSCATP00000019579	ENSCATP00000018326	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	3-phosphoinositide dependent protein kinase 1.	0.977
COL4A3	ITGA4	ENSCATP00000022746	ENSCATP00000010756	Collagen type IV alpha 3 chain.	Integrin subunit alpha 4; Belongs to the integrin alpha chain family.	0.771
ENSCATP00000003834	PLCG1	ENSCATP00000003834	ENSCATP00000022385	PTN_MK_N domain-containing protein.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.472
ENSCATP00000003834	STAT3	ENSCATP00000003834	ENSCATP00000017410	PTN_MK_N domain-containing protein.	Signal transducer and activator of transcription.	0.583
ENSCATP00000016044	IGF2	ENSCATP00000016044	ENSCATP00000040418	Protein kinase domain-containing protein.	Insulin like growth factor 2.	0.642
ENSCATP00000016044	PLCG1	ENSCATP00000016044	ENSCATP00000022385	Protein kinase domain-containing protein.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.565
ENSCATP00000016044	STAT3	ENSCATP00000016044	ENSCATP00000017410	Protein kinase domain-containing protein.	Signal transducer and activator of transcription.	0.436
FGFR1	IGF2	ENSCATP00000041327	ENSCATP00000040418	Fibroblast growth factor receptor.	Insulin like growth factor 2.	0.768
FGFR1	PLCG1	ENSCATP00000041327	ENSCATP00000022385	Fibroblast growth factor receptor.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.990
FLT1	IGF2	ENSCATP00000021745	ENSCATP00000040418	Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Insulin like growth factor 2.	0.850
FLT1	PLCG1	ENSCATP00000021745	ENSCATP00000022385	Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.565
FLT1	STAT3	ENSCATP00000021745	ENSCATP00000017410	Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Signal transducer and activator of transcription.	0.497
GHRL	GHSR	ENSCATP00000011288	ENSCATP00000043148	Ghrelin and obestatin prepropeptide.	Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family.	0.996
GHSR	GHRL	ENSCATP00000043148	ENSCATP00000011288	Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family.	Ghrelin and obestatin prepropeptide.	0.996
GHSR	IGF2	ENSCATP00000043148	ENSCATP00000040418	Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family.	Insulin like growth factor 2.	0.426
IGF2	ENSCATP00000016044	ENSCATP00000040418	ENSCATP00000016044	Insulin like growth factor 2.	Protein kinase domain-containing protein.	0.642
IGF2	FGFR1	ENSCATP00000040418	ENSCATP00000041327	Insulin like growth factor 2.	Fibroblast growth factor receptor.	0.768
IGF2	FLT1	ENSCATP00000040418	ENSCATP00000021745	Insulin like growth factor 2.	Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.850
IGF2	GHSR	ENSCATP00000040418	ENSCATP00000043148	Insulin like growth factor 2.	Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family.	0.426
ITGA4	COL4A3	ENSCATP00000010756	ENSCATP00000022746	Integrin subunit alpha 4; Belongs to the integrin alpha chain family.	Collagen type IV alpha 3 chain.	0.771