23 items (Cercocebus atys) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GSN	Gelsolin. (809 aa)
	SHTN1	Shootin 1. (636 aa)
	RUFY3	RUN and FYVE domain containing 3. (579 aa)
	FLOT2	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (505 aa)
	ANKFN1	Ankyrin repeat and fibronectin type III domain containing 1. (1149 aa)
	ARFGEF1	ADP ribosylation factor guanine nucleotide exchange factor 1. (1852 aa)
	ABL1	Tyrosine-protein kinase. (1149 aa)
	PTK2B	Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1018 aa)
	PLEKHG3	Pleckstrin homology and RhoGEF domain containing G3. (1367 aa)
	ABL2	Tyrosine-protein kinase. (1172 aa)
	KIF20B	Kinesin family member 20B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1823 aa)
	ENSCATP00000026377	Uncharacterized protein. (170 aa)
	DOCK8	Dedicator of cytokinesis 8; Belongs to the DOCK family. (2098 aa)
	CDH5	Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (785 aa)
	KRIT1	Uncharacterized protein. (736 aa)
	RACK1	Receptor for activated C kinase 1. (393 aa)
	KANK1	KN motif and ankyrin repeat domains 1. (1352 aa)
	RICTOR	RPTOR independent companion of MTOR complex 2. (1732 aa)
	BCAS3	BCAS3 microtubule associated cell migration factor. (950 aa)
	FAM49B	Family with sequence similarity 49 member B. (324 aa)
	WDPCP	WD repeat containing planar cell polarity effector. (711 aa)
	ROCK2	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1388 aa)
	RAP1B	Uncharacterized protein. (184 aa)

Your Current Organism:

Cercocebus atys

NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABL1	ABL2	ENSCATP00000017539	ENSCATP00000022840	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.927
ABL2	ABL1	ENSCATP00000022840	ENSCATP00000017539	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.927
DOCK8	KANK1	ENSCATP00000027858	ENSCATP00000038867	Dedicator of cytokinesis 8; Belongs to the DOCK family.	KN motif and ankyrin repeat domains 1.	0.485
ENSCATP00000026377	KRIT1	ENSCATP00000026377	ENSCATP00000028666	Uncharacterized protein.	Uncharacterized protein.	0.977
ENSCATP00000026377	PTK2B	ENSCATP00000026377	ENSCATP00000018439	Uncharacterized protein.	Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.429
FLOT2	ROCK2	ENSCATP00000016153	ENSCATP00000041767	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.418
KANK1	DOCK8	ENSCATP00000038867	ENSCATP00000027858	KN motif and ankyrin repeat domains 1.	Dedicator of cytokinesis 8; Belongs to the DOCK family.	0.485
KRIT1	ENSCATP00000026377	ENSCATP00000028666	ENSCATP00000026377	Uncharacterized protein.	Uncharacterized protein.	0.977
KRIT1	RAP1B	ENSCATP00000028666	ENSCATP00000044290	Uncharacterized protein.	Uncharacterized protein.	0.977
PTK2B	ENSCATP00000026377	ENSCATP00000018439	ENSCATP00000026377	Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Uncharacterized protein.	0.429
PTK2B	RAP1B	ENSCATP00000018439	ENSCATP00000044290	Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Uncharacterized protein.	0.429
PTK2B	ROCK2	ENSCATP00000018439	ENSCATP00000041767	Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.572
RAP1B	KRIT1	ENSCATP00000044290	ENSCATP00000028666	Uncharacterized protein.	Uncharacterized protein.	0.977
RAP1B	PTK2B	ENSCATP00000044290	ENSCATP00000018439	Uncharacterized protein.	Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.429
ROCK2	FLOT2	ENSCATP00000041767	ENSCATP00000016153	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.	0.418
ROCK2	PTK2B	ENSCATP00000041767	ENSCATP00000018439	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.572
RUFY3	SHTN1	ENSCATP00000006843	ENSCATP00000005690	RUN and FYVE domain containing 3.	Shootin 1.	0.540
SHTN1	RUFY3	ENSCATP00000005690	ENSCATP00000006843	Shootin 1.	RUN and FYVE domain containing 3.	0.540