42 items (Cercocebus atys) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MDK	Midkine. (143 aa)
	ENSCATP00000001531	Uncharacterized protein. (121 aa)
	ENSCATP00000001548	Protein kinase domain-containing protein. (250 aa)
	CSF1R	Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (975 aa)
	ENSCATP00000003424	HCLS1-associated protein X-1; Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools. (279 aa)
	ENSCATP00000003834	PTN_MK_N domain-containing protein. (60 aa)
	GMFG	Glia maturation factor; Belongs to the actin-binding proteins ADF family. GMF subfamily. (142 aa)
	NTF3	Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (278 aa)
	CCL27	C-C motif chemokine ligand 27. (112 aa)
	CD2AP	CD2 associated protein. (639 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
	IQGAP2	IQ motif containing GTPase activating protein 2. (1578 aa)
	PHPT1	Uncharacterized protein. (116 aa)
	RAPGEF3	Rap guanine nucleotide exchange factor 3. (925 aa)
	F11R	F11 receptor. (259 aa)
	CARMIL2	Capping protein regulator and myosin 1 linker 2. (1435 aa)
	HRAS	HRas proto-oncogene, GTPase. (189 aa)
	FES	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (856 aa)
	CARMIL3	Capping protein regulator and myosin 1 linker 3. (1372 aa)
	NTRK3	Tyrosine-protein kinase receptor. (866 aa)
	BCAS3	BCAS3 microtubule associated cell migration factor. (950 aa)
	CARMIL1	Capping protein regulator and myosin 1 linker 1. (1424 aa)
	ABI3	ABI family member 3. (366 aa)
	ABL1	Tyrosine-protein kinase. (1149 aa)
	PTK2B	Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1018 aa)
	BAIAP2L1	BAI1 associated protein 2 like 1. (511 aa)
	STAP1	Signal transducing adaptor family member 1. (295 aa)
	TEK	TEK receptor tyrosine kinase. (1124 aa)
	HCK	Tyrosine-protein kinase. (504 aa)
	TRPM2	Transient receptor potential cation channel subfamily M member 2. (1542 aa)
	CDK5	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
	CSF3	Colony stimulating factor 3. (204 aa)
	ABL2	Tyrosine-protein kinase. (1172 aa)
	TJP1	Tight junction protein 1; Belongs to the MAGUK family. (1742 aa)
	HAX1	HCLS1-associated protein X-1; Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools. (279 aa)
	SEMA3E	Semaphorin 3E; Belongs to the semaphorin family. (815 aa)
	NRP1	Neuropilin; Belongs to the neuropilin family. (926 aa)
	HCLS1	Hematopoietic cell-specific Lyn substrate 1. (476 aa)
	NOTCH2	Notch receptor 2. (2610 aa)
	DAPK3	Death associated protein kinase 3. (422 aa)
	BAIAP2L2	BAI1 associated protein 2 like 2. (529 aa)
	BAIAP2	BAI1 associated protein 2. (561 aa)

Your Current Organism:

Cercocebus atys

NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABI3	ABL1	ENSCATP00000044228	ENSCATP00000017539	ABI family member 3.	Tyrosine-protein kinase.	0.798
ABI3	ABL2	ENSCATP00000044228	ENSCATP00000022840	ABI family member 3.	Tyrosine-protein kinase.	0.798
ABI3	BAIAP2	ENSCATP00000044228	ENSCATP00000038672	ABI family member 3.	BAI1 associated protein 2.	0.461
ABI3	BAIAP2L1	ENSCATP00000044228	ENSCATP00000018985	ABI family member 3.	BAI1 associated protein 2 like 1.	0.461
ABI3	BAIAP2L2	ENSCATP00000044228	ENSCATP00000038392	ABI family member 3.	BAI1 associated protein 2 like 2.	0.412
ABL1	ABI3	ENSCATP00000017539	ENSCATP00000044228	Tyrosine-protein kinase.	ABI family member 3.	0.798
ABL1	ABL2	ENSCATP00000017539	ENSCATP00000022840	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.927
ABL1	BAIAP2	ENSCATP00000017539	ENSCATP00000038672	Tyrosine-protein kinase.	BAI1 associated protein 2.	0.524
ABL1	BAIAP2L1	ENSCATP00000017539	ENSCATP00000018985	Tyrosine-protein kinase.	BAI1 associated protein 2 like 1.	0.419
ABL1	CDK5	ENSCATP00000017539	ENSCATP00000021891	Tyrosine-protein kinase.	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily.	0.448
ABL1	ENSCATP00000001548	ENSCATP00000017539	ENSCATP00000001548	Tyrosine-protein kinase.	Protein kinase domain-containing protein.	0.448
ABL1	HRAS	ENSCATP00000017539	ENSCATP00000014290	Tyrosine-protein kinase.	HRas proto-oncogene, GTPase.	0.404
ABL1	NTRK3	ENSCATP00000017539	ENSCATP00000016306	Tyrosine-protein kinase.	Tyrosine-protein kinase receptor.	0.899
ABL2	ABI3	ENSCATP00000022840	ENSCATP00000044228	Tyrosine-protein kinase.	ABI family member 3.	0.798
ABL2	ABL1	ENSCATP00000022840	ENSCATP00000017539	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.927
ABL2	BAIAP2	ENSCATP00000022840	ENSCATP00000038672	Tyrosine-protein kinase.	BAI1 associated protein 2.	0.531
ABL2	BAIAP2L1	ENSCATP00000022840	ENSCATP00000018985	Tyrosine-protein kinase.	BAI1 associated protein 2 like 1.	0.419
ABL2	NTRK3	ENSCATP00000022840	ENSCATP00000016306	Tyrosine-protein kinase.	Tyrosine-protein kinase receptor.	0.769
BAIAP2	ABI3	ENSCATP00000038672	ENSCATP00000044228	BAI1 associated protein 2.	ABI family member 3.	0.461
BAIAP2	ABL1	ENSCATP00000038672	ENSCATP00000017539	BAI1 associated protein 2.	Tyrosine-protein kinase.	0.524