(12 nodes) Early phagosome network (Cercocebus atys)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SYT11	Synaptotagmin 11. (431 aa)
	ENSCATP00000030079	Uncharacterized protein. (211 aa)
	UNC93B1	Unc-93 homolog B1, TLR signaling regulator. (597 aa)
	PLA2G5	Phospholipase A(2). (138 aa)
	ENSCATP00000020353	Uncharacterized protein. (64 aa)
	RAB5A	Uncharacterized protein. (215 aa)
	RAB31	RAB31, member RAS oncogene family. (194 aa)
	ENSCATP00000007470	Uncharacterized protein. (174 aa)
	SYK	Non-specific protein-tyrosine kinase. (637 aa)
	TLR7	Toll-like receptor 7; Belongs to the Toll-like receptor family. (1049 aa)
	SYT7	Synaptotagmin 7. (686 aa)
	APPL2	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (664 aa)

Your Current Organism:

Cercocebus atys

NCBI taxonomy Id: 9531
Other names: C. atys, Cercocebus torquatus atys, sooty mangabey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APPL2	ENSCATP00000007470	ENSCATP00000034066	ENSCATP00000007470	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.	Uncharacterized protein.	0.857
APPL2	ENSCATP00000020353	ENSCATP00000034066	ENSCATP00000020353	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.	Uncharacterized protein.	0.857
APPL2	ENSCATP00000030079	ENSCATP00000034066	ENSCATP00000030079	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.	Uncharacterized protein.	0.857
APPL2	RAB31	ENSCATP00000034066	ENSCATP00000008134	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.	RAB31, member RAS oncogene family.	0.857
APPL2	RAB5A	ENSCATP00000034066	ENSCATP00000019580	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.	Uncharacterized protein.	0.857
ENSCATP00000007470	APPL2	ENSCATP00000007470	ENSCATP00000034066	Uncharacterized protein.	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.	0.857
ENSCATP00000020353	APPL2	ENSCATP00000020353	ENSCATP00000034066	Uncharacterized protein.	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.	0.857
ENSCATP00000030079	APPL2	ENSCATP00000030079	ENSCATP00000034066	Uncharacterized protein.	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.	0.857
RAB31	APPL2	ENSCATP00000008134	ENSCATP00000034066	RAB31, member RAS oncogene family.	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.	0.857
RAB5A	APPL2	ENSCATP00000019580	ENSCATP00000034066	Uncharacterized protein.	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.	0.857
TLR7	UNC93B1	ENSCATP00000042815	ENSCATP00000028100	Toll-like receptor 7; Belongs to the Toll-like receptor family.	Unc-93 homolog B1, TLR signaling regulator.	0.960
UNC93B1	TLR7	ENSCATP00000028100	ENSCATP00000042815	Unc-93 homolog B1, TLR signaling regulator.	Toll-like receptor 7; Belongs to the Toll-like receptor family.	0.960